Effect of Family Function-Based Adherence on Supportive Periodontal Care Prognosis: A Retrospective Analysis.

Introduction: Adherence to supportive periodontal care (SPC) is essential for preventing disease recurrence and maintaining oral health. Psychological and emotional support from family members may play a vital role in sustaining long-term adherence, yet the influence of family function on SPC adherence and outcomes remains underexplored.

Objective: To evaluate the impact of family function on adherence to SPC and its subsequent effect on periodontal prognosis.

, a new species of Gesneriaceae in Vietnam.

Based on morphological comparisons, literature reviews, and molecular systematic studies, a new species from South Vietnam, F.Wen, T.V.

[Machine Learning-based Prediction of Carbon Fluxes in Terrestrial Ecosystems in China and Its Response to Land Use Change].

Current carbon flux data for China's terrestrial ecosystems have limitations, such as short time series and low resolution. Generating longer time series and higher-resolution carbon flux data for these ecosystems is crucial for studying their temporal and spatial variation characteristics and for analyzing the impact of land use changes on carbon fluxes. This study constructed four machine learning models using flux data from Chinese sites and relevant predictor variables, identifying the random forest model as the best predictive model.

Effect of Hyperperfusion on Successful Collection of Arterial Blood Gas Specimens in Patients With Acute Heart Failure.

Background: This study aimed to explore the effect of radial artery flow hyperperfusion on the successful collection of radial artery blood gas specimens in patients with acute heart failure.

Methods: From February 2023 to December 2024, 548 patients with acute heart failure in the database of the emergency rescue room of our hospital were divided into two groups: non-hyperperfusion group and hyperperfusion group. In the hyperperfusion group, arterial blood gas was collected using the radial artery hyperinfusion method (improving radial artery perfusion by blocking arteries other than the radial artery in the forearm using a customized sphygmomanometer with a double-airbag hollow cuff).

Gut microbiota and breast cancer risk: a Mendelian randomization study stratified by ER status.

Background: The potential causal relationship between gut microbiota (GM) and breast cancer (BC), particularly its estrogen receptor (ER)-positive (ER+) and ER-negative (ER-) subtypes, remains insufficiently characterized.

Method: We conducted a two-sample Mendelian randomization (MR) analysis to examine genetically predicted causal associations between 473 GM features (abundance in stool) and BC, including overall BC (Ncase = 24,270, Ncontrol = 222,078), ER+ BC (Ncase = 14,540, Ncontrol = 221,705) and ER- BC (Ncase = 9,724, Ncontrol = 221,705).

Result: The MR results demonstrated differential causal associations between GM and BC subtypes: For overall BC risk, lower Barnesiella abundance (OR = 0.

 (Gesneriaceae), a new species identified by both morphological and molecular evidence from limestone caves in Guangxi, China.

, a new species of Gesneriaceae, is a typically cave-dwelling species from the limestone region in Guangxi, China. Morphologically, this new species resembles , but can be readily distinguished by differences in corolla limb lobe shape, calyx lobe surface texture, pistil style length, and central staminode length. Molecular evidence supports its close phylogenetic relationship with despite their morphological distinctness.

Association between the urine tobacco metabolite levels and physical health in Chinese primary school students with secondhand smoke exposure.

Background: There is limited epidemiological evidence on the association between secondhand smoke exposure and growth and developmental problems in children and adolescents. This study aimed to explore the relationship between urinary levels of nicotine, cotinine, and trans-3'-hydroxycotinine and physical health outcomes in Chinese children.

Methods: This cross-sectional study included 491 children aged 8 to 12 years from a primary school in 2023.

Dihydroartemisinin targets the miR-497-5p/SOX5 axis to suppress tumor progression in non-small cell lung cancer.

Introduction: Non-small cell lung cancer (NSCLC) remains a lethal malignancy with limited therapeutic options. Although dihydroartemisinin (DHA) exhibits anticancer properties, its mechanisms in NSCLC are incompletely understood. This study investigated the role of the miR-497-5p/SOX5 axis in mediating DHA's effects on NSCLC.

Combining multiple high-resolution in-situ techniques to understand the metals mobilization at anoxic-oxic interfaces in flooded industrial soils.

Industrial sites in coastal cities experience fluctuating redox conditions driven by climate change, forming anoxic-oxic interfaces and influencing the availability of heavy metals (HMs). What remains elusive is how oxygen contents influence the formation of anoxic-oxic interfaces and HMs mobilization in industrial soils with varying physicochemical properties. Here we investigated the mobilization mechanisms of HMs (Fe, Mn, Cu, Ni, and Zn) at anoxic-oxic interfaces in different depths soils at a historical industrial site using high-resolution in-situ techniques, including planar optodes (PO) and diffusive gradients in thin-films (DGT).

Global, Regional and National Burden of Chronic Hepatitis C, 1990-2021: A Systematic Analysis for the GBD Study 2021.

Chronic hepatitis C (CHC) remains a major global health burden, disproportionately affecting low-resource regions. Despite direct-acting antiviral (DAA) advancements, persistent liver complications and socioeconomic disparities hinder progress. This study aims to analyse CHC burden trends (1990-2021) across sociodemographic index (SDI), age, gender and geography using Global Burden of Disease (GBD) 2021 data.

Right C7 neurotomy at the intervertebral foramen plus intensive speech and language therapy versus intensive speech and language therapy alone for chronic post-stroke aphasia: multicentre, randomised controlled trial.

Objective: To evaluate whether right neurotomy of the seventh cervical nerve (C7) at the intervertebral foramen plus intensive speech and language therapy (SLT) improves language function compared intensive SLT alone in patients with chronic aphasia after stroke.

Design: Multicentre, assessor blinded, randomised controlled trial.

Setting: Four centres in mainland China.

 (Gesneriaceae), a new species from Guangxi Zhuang Autonomous Region, China.

, endemic to the limestone area in Dahua County, Guangxi Zhuang Autonomous Region, China, is described and illustrated here. This species is distinguished from by leaves sessile or with indistinct short petioles ( distinctly petiolate, 21-42 mm long in , the following comparisons are in the same order) and blades oblanceolate, narrowly obovate to obovate ( ovate to broadly ovate); bracts smaller, lanceolate (3-4× ca. 1 mm) ( ovate to narrowly ovate, 18-25 × 9-14 mm); filaments glabrous and ca.

Quercetin ameliorates hyperuricemic nephropathy through improving gut dysfunctions and decreasing gut bacteria-derived uremic toxins.

Background: Hyperuricemia (HUA) is closely associated with gut dysbiosis, yet the role of microbial metabolism in hyperuricemic nephropathy (HN) remains poorly understood. Quercetin has shown urate-lowering and nephroprotective effects, but its therapeutic mechanisms, particularly in modulating the gut microbiome and microbial metabolism, remain elusive.

Purpose: This study investigates the therapeutic effects of quercetin on HN and explores its role in regulating host-microbial co-metabolism.

Monitoring the trends of Angiostrongylus cantonensis infection in humans and Pomacea spp. Snails in Dali, Yunnan, China, 2007-2021.

We summarize historical events related to angiostrongyliasis and analyze surveys of clinically diagnosed and suspected cases of angiostrongyliasis in Dali from 2007 to 2021. We also randomly tested market sold Pomacea spp. snails to detect whether Angiostrongylus cantonensis was present in Dali market stalls from 2008 to 2021.

Mapping the Water-Economic Cascading Risks within a Multilayer Network of Supply Chains in China.

Local water scarcity shocks can threaten supply chains by triggering cascading economic risks embedded in the flow of goods and services. However, the lack of cascading risk modeling techniques makes it challenging to determine how disruptions in one economic sector propagate to others through the supply chain. In this study, we construct a national multilayer cascading risk model using 2017 multiregional input-output data from China and simulate shock propagation.

Reduction of antimony bioavailability with the application of stable exogenous organic matter: a comparative study between rice straw and manure compost.

Considering the widespread use of organic amendments to improve soil quality and enhance soil carbon sequestration, it is crucial to understand their impact on the bioavailability of metalloids in soils. Antimony (Sb), a priority pollutant, is particularly impacted by organic matter, yet the effects of different organic amendments-varying in stability and composition-on Sb bioavailability remain unclear. This study investigates the influence of different organic amendments, rice straw and compost, on Sb bioavailability in the rice-soil system, with rice ingestion being a major Sb exposure pathway in humans.

A better balance: Energy transition and industrial restructuring for a sustainable economy-climate-environment pathway.

Promoting socioeconomic development while curbing carbon emission and pollutants necessitates a balance among multiple conflicting objectives. Structural adjustments to industrial production and energy consumption can better balance the economy, climate and environment systems and achieve balanced development of multiple objectives. In this study, we propose a novel optimization method by integrating the coupling coordination degree model into traditional multi-objective optimization model and apply it to Jiangsu Province, China.

Evaluating the Mechanism Underlying Multi-Compound Synergy of Banxia Decoction in the Treatment of Hashimoto's Thyroiditis Based on Network Pharmacology and Molecular Docking.

Objective: We aimed to utilize network pharmacological analysis and molecular docking to elucidate the potential mechanisms of Banxia Decoction (BD) action in the treatment of Hashimoto's thyroiditis (HT).

Materials And Methods: Active compounds and HT-related targets were predicted using databases and the intersection of the results was taken. STRING and DAVID 6.

Investigation of Solution Microstructure in Ferric Sulfate Coagulation-Assisted Precipitation of Fluoride Ions.

The solution microstructure during the ferric sulfate-assisted precipitation of calcium fluoride was systematically investigated using molecular dynamics simulations and DFT methods. The microscopic behavior of various ions in a calcium fluoride box in the presence of ferric sulfate was simulated using MD. The corresponding hydrated cluster structures were extracted from the MD trajectory; then, the structure was optimized and the frequency was calculated at the B3LYP/6-311++G(d, p) level.

Oscillatory control over representational geometry of sequence working memory in macaque frontal cortex.

To process sequential streams of information, e.g., language, the brain must encode multiple items in sequence working memory (SWM) according to their ordinal relationship.

Relationship between dietary intake and growth and development in Chinese pupils.

Background: A nutritional diet is essential for children's growth and development. This study aimed to investigate the relationship between dietary intake and growth and development of pupils to provide more specific nutritional recommendations for their healthy growth.

Methods: This cross-sectional study included 592 pupils, and standardized questionnaires were used to collect information on students' sociodemographic characteristics, lifestyle habits and dietary intake.

Successful conversion surgery following tislelizumab with chemotherapy in a patient with stage IIIC lung adenocarcinoma harboring RET fusions: A case report and review of the literature.

Immune checkpoint inhibitors (ICIs) have emerged as a beacon of hope for most patients with stage III non-small cell lung cancer (NSCLC) who are no longer surgical candidates. However, the literature on the use of immunotherapy in patients with NSCLC with rearranged during transfection (RET) gene fusions is scant. The present study reports the case of a 61-year-old female patient, diagnosed with stage IIIC lung adenocarcinoma, exhibiting two RET gene fusions and high programmed death-ligand 1 expression.

Hsp70 incompletely disaggregates misfolded K488X-menin to promote tumourigenesis in a family with multiple endocrine neoplasia type 1.

Multiple endocrine neoplasia type 1 (MEN1) is caused by germline mutations in the MEN1 gene, including nonsense mutations and missense variants, which result in the formation of truncated inactive menin protein and some of which cause degradation of mutant menin proteins. Here, we describe a c.1462 A > T (p.

Acute Moderate Hemodynamic Stroke Secondary to Large Vessel Stenosis: A Case Series Exploring Imaging Characteristics and Endovascular Treatment Outcomes.

Background: This study aimed to characterize the imaging features and the outcomes of endovascular treatment (EVT) in patients with moderate hemodynamic stroke due to large vessel stenosis.

Methods: Data from patients with moderate hemodynamic stroke due to large vessel stenosis who underwent EVT at a single center between January 2021 and June 2024 were retrospectively analyzed. Hemodynamic stroke was defined as infarction in the watershed area on diffusion-weighted imaging and hypoperfusion on perfusion-weighted imaging.

A cost-effective strategy for identifying Angiostrongylus spp. larvae in Achatina fulica: combined morphological and molecular biology.

Background: The detection of Angiostrongylus spp. larvae in intermediate host snails is a critical epidemiological investigation, essential for the effective control of disease outbreaks. Compared to molecular biological detection methods, lung microscopy, a traditional pathogen morphological detection approach, is susceptible to oversights and exhibits relatively lower sensitivity.