Efficient Urea Oxidation on MnCO/Ni(OH) Nanoflower Arrays Via Interfacial Coupling.

The electrochemical urea oxidation reaction (UOR) presents an energy-efficient alternative to the sluggish oxygen evolution reaction (OER), operating at a substantially lower thermodynamic potential and thereby reducing the energy input for hydrogen production by approximately 70%. Simultaneously, UOR facilitates wastewater remediation, offering dual environmental and energy benefits. In this work, we report a MnCO/Ni(OH) heterostructured nanoflower array directly grown on conductive carbon cloth that exhibits outstanding UOR catalytic activity and stability.

Effects of Increased Calcium, Magnesium, and Potassium Ion Concentrations on Survival Conditions, Growth Performance, and Physiological Parameters in Sea Urchin ().

This study examined the effects of calcium, magnesium, and potassium ion concentrations on through seven experimental rearing groups: two calcium ion levels (550 mg/L and 733 mg/L), two magnesium ion levels (1727 mg/L and 2302 mg/L), two potassium ion levels (533 mg/L and 710 mg/L), and a control. After 45 days of cultivation, 733 mg/L of calcium ions significantly reduced the survival rate, while 550 mg/L of calcium ions had no significant adverse effects on survival, growth (SGR), the feed conversion ratio (FCR), gonad colour, or immune enzyme activity, and it significantly increased the gonad index (GI). Meanwhile, 2302 mg/L of magnesium ions caused 100% mortality within 2 days, and 1727 mg/L of magnesium ions significantly reduced the survival rate and SGR while increasing the FCR.

A Universal Voltage-Enhancement Strategy Based on Multifunctional Ligand-Mediated Modulation for Na-Layered Oxide Cathode.

Sodium-ion batteries (SIBs) have emerged as promising energy storage solutions due to resource abundance and low cost, yet their practical deployment is hindered by limited operating voltages of cathode materials. Herein, we propose a universal ligand-field engineering strategy to enhance voltage through electronic structure modulation in transition metal oxides. Using the NaMgMnO as a model system, weak-field ligands are introduced to alter the coordination environment of MnO octahedra.

Catalytic cooperation between Ru and Pd atoms on hierarchical porous Ce-based oxide for boosting engine exhaust purification.

Simultaneous oxidation of soot and CH emitted from natural gas-diesel dual fuel engine is a new challenge. Herein, a robust catalyst of binary Ru-Pd components supported on three-dimensional ordered macro-mesoporous cerium-zirconium oxide (RuPd/3DOMM-CZO) is elaborately constructed. Ordered macro-mesopore structure in novel hierarchical porous cerium-zirconium oxide can respectively enhance mass transfer of soot and gaseous reactants, and binary Ru-Pd active components can improve activation for NO and CH.

Characterization of BpLPMO10 from Bacillus paralicheniformis: A bi-functional AA10 LPMO with chitin-preferential activity and strong exo-enzyme synergy.

LPMOs are copper metalloenzymes that facilitate the conversion of challenging polysaccharides like cellulose and chitin. This study focuses on the AA10 family LPMO gene (BpLPMO10) cloned from the chitin-degrading bacterium Bacillus paralicheniformis and expressed in Escherichia coli. Using the 2,6-DMP assay, the optimal reaction conditions for BpLPMO10 were determined to be pH 8.

Diagnosis and treatment of Ascarial pancreatitis: a case report and literature review.

Background: The prevalence of diseases caused by parasites has decreased due to improved sanitary conditions. Acute pancreatitis caused by parasites, especially Ascaris lumbricoides worms, is relatively rare and difficult to diagnose. In some cases, it may even be misdiagnosed as idiopathic acute pancreatitis due to the difficulty of identifying the underlying cause.

Knowledge-based trade-off prediction for NSCLC treatment planning using multi-output regression.

Background: Knowledge-based planning (KBP) is a data-driven approach that utilizes the knowledge from previous high-quality treatment plans to predict dose-volume histogram (DVH) parameters for organs-at-risk (OARs) in new cases. Research has demonstrated that KBP enhances plan quality, minimizes inter-patient and inter-institution variability, and significantly boosts time efficiency. However, current state-of-the-art KBP approaches only generate one set of planning goals for one point on the Pareto optimal surface without considering potential planning trade-offs.

Association of ophthalmic origin aneurysms with abnormally-enhanced hemodynamic stresses at the arterial wall.

Purpose: To investigate hemodynamic parameters associated with ophthalmic aneurysms using computational fluid dynamic (CFD) analysis.

Materials And Methods: Sixty patients with or without ophthalmic origin aneurysms were enrolled, including 30 patients with and 30 patients without ophthalmic aneurysms. The demography, vascular diameter and angles, and hemodynamic parameters were analyzed.

The spatial distribution characteristics and influencing factors of key villages in rural tourism in China.

Rural tourism key villages in China serve as critical nodes driving the development of rural tourism. Based on a dataset of 1,195 key villages, this study employs Ripley's K-function and geographic detector methods to investigate their spatial distribution patterns and influencing factors. The findings reveal: ① The spatial distribution of rural tourism key villages demonstrates a strong directional alignment toward major cities and tourist attractions; ② Significant regional disparities exist in aggregation scales, with the eastern region exhibiting a substantially higher concentration than the central and western regions; ③ Both natural environmental factors and socio-economic factors influence rural tourism key villages, with road network density, river network density, and per capita disposable income exerting the most pronounced effects.

pH-regulated structural and interfacial properties of OSA starch/whey protein fiber complexes to improve the storage and digestive stability of citrus essential oil emulsions.

In this study, an emulsion delivery system for citrus essential oil (CEO) based on whey protein fiber (WPF) and OSA modified starch (OFE) was successfully developed, and the stability and bioaccessibility of the CEO emulsion were enhanced by pH regulation. The impact of pH-regulated and OFE modification on the structure, emulsification properties, and CEO release behavior of WPF-OFE was systematically examined. Fourier transform infrared spectroscopy (FTIR) and molecular docking analyses revealed that OFE provided the basis for the formation of the ordered structure, and the main interactions between WPF and OFE were hydrogen bonding and electrostatic interactions.

Delocalized electrolyte design enables 600 Wh kg lithium metal pouch cells.

The development of high-energy lithium metal batteries (LMBs) is essential for advances in next-generation energy storage and electric vehicle technologies. Nevertheless, the practical applications of LMBs are constrained by current electrolyte designs that inherently rely on dominant solvation structures, preventing transformative progress in performance optimization. Here, we address this limitation through a delocalized electrolyte design that fosters a more disordered solvation microenvironment, thereby mitigating dynamic barriers and stabilizing interphases.

Dynamic three-dimensional culture enhances tunneling nanotubes-mediated mitochondrial transfer in mesenchymal stromal cells to accelerate wound healing.

Mesenchymal stromal cells (MSCs) have shown promise in treating various diseases, and optimizing their therapeutic potential is a crucial objective in MSCs-based clinical applications. The microenvironment, particularly three-dimensional (3D) culture systems, plays a pivotal role in regulating the fate determination and enhancing the therapeutic potential of MSCs. Currently, the mechanisms governing the interactions between MSCs cultured in a dynamic 3D system and host recipient cells remain incompletely understood.

Resolving Hydraulic Resistances in Thin-Film Composite Polyamide Nanofiltration Membranes.

Thin-film composite (TFC) nanofiltration (NF) membranes are widely used in water treatment and resource recovery. Researchers generally take for granted that the dense polyamide rejection film dictates the overall hydraulic resistance of these membranes, neglecting the contributions of the substrate and the transverse transport of water to reach substrate pores. To address this critical gap, we developed a resistance-in-series model to quantify the resistances from the polyamide film, substrate, and transverse transport.

Risk factors and nomogram prediction model for recurrence after radiofrequency ablation in patients with persistent atrial fibrillation.

Background: Recurrence of atrial fibrillation (AF) after radiofrequency catheter ablation (RFA) remains a major clinical challenge in patients with persistent AF. This study aimed to identify independent risk factors for post-ablation recurrence and to develop a nomogram prediction model integrating clinical, laboratory, and echocardiographic parameters.

Methods: In this retrospective study, 306 patients with persistent AF who underwent first-time RFA between June 2021 and June 2024 were enrolled.

Multimodal sensing system based on phenylboric acid-COF/RhB ratio fluorescence: highly sensitive detection of ovarian cancer biomarker, smartphone-assisted field analysis and information encryption and anti-counterfeiting integration.

It is essential to develop an innovative technology with high sensitivity and real-time detection for the early diagnosis of ovarian cancer. The cross-disciplinary application of multifunctional materials represents a significant trend in contemporary sensing research. In this paper, a ratio-type fluorescence sensing platform RhB/TFBBPY-COF@PBA was constructed from the covalent organic framework (COF) co-functionalized by phenylboric acid and rhodamine B (RhB).

Identification of rs2036527 as a cis-regulatory variant for CHRNA3 and CHRNA5 by allele-specific expression and implications for nicotine dependence and lung cancer.

Background And Objectives: Numerous genome-wide association studies suggest that rs1051730 is significantly associated with nicotine dependence and further lung cancer in Caucasian. Since rs1051730 is a synonymous variant at CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit), it might be hypothesized that the causal variant might be other SNP(s) in strong linkage disequilibrium (LD).

Methods: LD analysis and functional genomics work, including chromosome conformation capture (3C), luciferase assay, and chromatin immunoprecipitation (ChIP), were performed.

Laser writing of spin defects in polymers.

Technologies based on quantum effects of spin defects, such as computation, communication, sensing, and anticounterfeiting, have developed rapidly. However, limited by specific crystal structure required for spin defects, wide extension of their application faces challenges. A notable challenge is fabricating spin defects in general-purpose, low-cost amorphous materials such as polymers.

Efficacy and safety of insulin sensitisers for treating type 2 diabetes: a network meta-analysis.

Purpose: Thiazolidinediones (TZDs), including pioglitazone and rosiglitazone, and non-TZD insulin sensitisers (chiglitazar sodium) demonstrate potential; however, their comparative efficacy and safety remain unclear. We aimed to analyse the efficacy and safety of commonly used insulin sensitisers, including chiglitazar sodium, sitagliptin, pioglitazone, and rosiglitazone for treating type 2 diabetes mellitus (T2DM).

Methods: A computer-based search was conducted in the China National Knowledge Infrastructure, Wanfang Data, the VIP database, PubMed, Embase, and Cochrane Library databases from the establishment date of each database to January 2025.

Development and Application of a Multiplex Real-Time TaqMan qPCR Assay for the Simultaneous Detection of African Swine Fever Virus, Classical Swine Fever Virus, Porcine Reproductive and Respiratory Syndrome Virus, Pseudorabies Virus, and Porcine Circovirus Type 2.

Since its emergence in China in 2018, African swine fever virus (ASFV) has posed a severe threat to the pig farming industry due to its high transmissibility and mortality rate. The clinical signs of ASFV infection often overlap with those caused by other swine viruses such as classical swine fever virus (CSFV), porcine reproductive and respiratory syndrome virus (PRRSV), pseudorabies virus (PRV), and porcine circovirus type 2 (PCV2), making timely and precise diagnosis a considerable challenge. To address this, we established a TaqMan-based multiplex real-time quantitative PCR (qPCR) assay capable of simultaneously detecting ASFV, CSFV, PRRSV, PRV, and PCV2.

The Influence of Parent Pairs with Different Genetic Distances on the Genetic Diversity of Offspring in .

To identify effective strategies for preserving the genetic diversity of populations, this study employed 15 SSR loci and SSR-seq technology to construct three parental mating groups based on different genetic distances: relatively distant (0.33640), relatively close (0.13051), and mixed (0.

Systemic immune-inflammation index and postoperative sleep disturbance in elderly patients with total joint arthroplasty: A prospective cohort study.

The systemic immune-inflammation index (SII) has been implicated in various pathological conditions; however, its role in postoperative sleep disturbance (PSD) remains unclear. This prospective cohort study aimed to investigate the association between SII and PSD in elderly patients undergoing total joint arthroplasty. A total of 500 patients (median age: 70 years, IQR: 67-75) were enrolled between August 2023 and October 2024.

Ultrasound-based radiomics combined with B3GALT4 level to predict sentinel lymph node metastasis in primary breast cancer.

Objective: To evaluate the value of the clinical model for predicting axillary lymph node metastasis (ALNM) of breast cancer before operation by integrating ultrasound (US) and β-1,3-galactosyltransferase-4 (B3GALT4) expression level of the primary tumor.

Methods: A total of 135 breast cancer patients who underwent US examination and axillary lymph nodes dissection (ALND) were enrolled. They were randomly divided into a training group (95 cases) and a verification group (40 cases).

Self-referenced ratiometric electrochemical biosensor based on covalent organic framework assembled MXene for stain-resistance and sensitive sensing of dopamine.

Dopamine (DA) is not only an important neurotransmitter involving in the regulation of life activities, but also a typical biomarker of neurodegenerative diseases. Accurate detection of DA content is of great significance for early diagnosis and treatment of related illness. Herein, a ratio electrochemical sensing platform was constructed based on covalent organic framework (COF) assembled MXene composite nanomaterials for sensitive, selective and accurate detection of DA.

Development and preliminary verification of the scale of care needs of family caregivers of patients with bladder cancer undergoing urostomy.

As the main undertakers of home care for urostomy patients after discharge, family caregivers play an important role in patients' postoperative recovery. Family caregivers of patients with urostomy may be under greater pressure than patients themselves, and there is a heavy burden on caregivers, and their care needs are complicated and urgent. However, there is a lack of research on the care needs of family caregivers of bladder cancer patients with urostomy, and tools to assess the specific needs of family caregivers of bladder cancer patients with urostomy are lacking.