Comparison of short- and long-term outcomes among total laparoscopic, laparoscopic-assisted, and open total gastrectomies for advanced gastric cancer patients after neoadjuvant chemotherapy: a multicenter retrospective cohort study.

Objective: To evaluate the short- and long-term outcomes of totally laparoscopic, laparoscopic-assisted, and open total gastrectomy in gastric cancer patients after neoadjuvant therapy.

Methods: This multicenter retrospective cohort study was conducted to collect clinical data from 289 patients who underwent total radical gastrectomy after neoadjuvant therapy at five centers. The patients were divided into three groups according to the surgical method they received: totally laparoscopic, laparoscopic-assisted, and open groups.

Large-scale protein interactome reveals lineage-specific genes driving plant-parasitic nematode adaptive innovations.

Mounting evidence suggests that lineage-specific genes drive phenotype diversity. Plant-parasitic nematodes (PPNs), among the most destructive plant pathogens, have evolved innovated traits required for plant parasitism, yet the genetic basis remains unclear. Here, we identify PPN lineage-specific genes (PPNLSGs) and analyze the large-scale protein interactome of their encoded proteins (PPNLSPs).

Seasonality and Vertical Structure of Microbial Communities in Alpine Wetlands.

The soil microbial community plays a crucial role in the elemental cycling and energy flow within wetland ecosystems. The temporal dynamics and spatial distribution of soil microbial communities are central topics in ecology. While numerous studies have focused on wetland microbial community structures at low altitudes, microbial diversity across seasons and depths and their environmental determinants remain poorly understudied.

Acid-modified Cu-Ce/HZSM-5 adsorbent removes trace phosphorus impurities from recycled hydrogen during polysilicon production.

In this study, an acid-modified Cu-Ce/HZSM-5 bimetallic adsorbent was developed for the removal of trace PH impurities from simulated recycled hydrogen in a chemical vapor deposition furnace for polysilicon production. A systematic examination was subsequently conducted to examine the effects of acidic substance type and concentration, and the addition of Ce on the adsorbent's ability to remove PH. The results showed that the adsorbent, when treated with 13% HNO and an appropriate level of Ce (  :  = 1 : 40), exhibited superior adsorption performance, achieving a PH breakthrough adsorption capacity of 135.

Mycoidesin, a novel lantibiotic, exhibits potent bacteriostatic activity against and effectively controls its growth in beef.

Unlabelled: can cause severe listeriosis, with the consumption of contaminated food being an important route of its transmission. Biopreservatives can be used for the prevention and control of in food. In this study, we identified a novel lantibiotic, mycoidesin, with potent bacteriostatic activity against .

CXCL8 upregulation mediates inflammatory cell infiltration and accelerates abdominal aortic aneurysm progression.

Objective: To explore abdominal aortic aneurysm (AAA) pathogenesis and identify early diagnostic markers, providing a theoretical basis for novel preventive and therapeutic strategies.

Methods: Gene expression profiles were retrieved from the Gene Expression Omnibus database (datasets: GSE7084, GSE47472, and GSE57691) comprising messenger RNA data from the aortic samples of 69 patients with AAA and 25 non-AAA controls. Data were merged and normalized; bioinformatics analysis was conducted on upregulated differentially expressed genes.

Cryo-EM structure of a minimal reaction center-light-harvesting complex from the phototrophic bacterium Chloroflexus aurantiacus.

Photosynthetic organisms have developed various light-harvesting antenna systems to capture light and transfer energy to reaction centers (RCs). Simultaneous utilization of the integral membrane light-harvesting antenna (LH complex) and the extrinsic antenna (chlorosomes) makes the phototrophic bacterium Chloroflexus (Cfx.) aurantiacus an ideal model for studying filamentous anoxygenic phototrophs (FAPs).

Exercise Training After Myocardial Infarction Enhances Endothelial Progenitor Cells Function via NRG-1 Signaling.

Vascular regeneration after myocardial infarction (MI) is essential to improve myocardial ischemia, delay post-infarction ventricular remodeling, and improve the long-term prognosis of MI. Endothelial progenitor cells (EPCs) play important roles in the functional repair and homeostatic maintenance of the vascular endothelium. Exercise training stimulates EPC mobilization and increases the number of circulating EPCs, which has beneficial effects on the restoration of vascular integrity and hemodynamic reconstitution.

ABA-auxin cascade regulates crop root angle in response to drought.

Enhancing drought resistance through the manipulation of root system architecture (RSA) in crops represents a crucial strategy for addressing food insecurity challenges. Abscisic acid (ABA) plays important roles in drought tolerance; yet, its molecular mechanisms in regulating RSA, especially in cereal crops, remain unclear. In this study, we report a new mechanism whereby ABA mediates local auxin biosynthesis to regulate root gravitropic response, thereby controlling the alteration of RSA in response to drought in cereal crops.

Efficacy and safety of a dedicated venous stent for the treatment of iliofemoral venous obstruction: A single center experience.

Background: Endovascular recanalization with venous stenting is the preferred treatment for iliofemoral venous obstruction. We reviewed our institutional experience and mid-term outcomes with endovascular therapy for iliofemoral venous obstruction using the Venovo Self-expanding Venous Stent (BARD Peripheral Vascular, Inc., Tempe, AZ, USA).

Coexpression Regulation of New and Ancient Genes in the Dynamic Transcriptome Landscape of Stem and Rhizome Development in "Bainianzhe"-An Ancient Chinese Sugarcane Variety Ratooned for Nearly 300 Years.

The sucrose yield in sugarcane largely depends on stem morphology, including length, diameter and sugar content, making sugarcane stem a key trait in breeding. The "Bainianzhe" variety from Songxi County, Fujian Province, possesses both aerial stems and rhizomes, providing a unique model for studying stem development. We performed a spatiotemporal transcriptomic analysis of the base, middle and apical sections of both aerial stems and rhizomes.

Benzoic acid facilitates ANF in monocot crops by recruiting nitrogen-fixing Paraburkholderia.

Associative nitrogen fixation contributes large portion of N input to agro-ecosystems through monocot-diazotrophic associations. However, the contribution of associative nitrogen fixation is usually neglected in modern agriculture, and the underlying mechanisms of association between monocot and diazotrophs remain elusive. Here, we demonstrated that monocot crops employ mucilage and associated benzoic acid to specially enrich diazotrophic partners in response to nitrogen deficiency, which could be used for enhancing associative nitrogen fixation in monocot crops.

Millmerranones G, a meroterpene isolated from a mangrove-derived fungus sp. GXIMD 03004.

One new meroterpene derivative, millmerranones G (), and three known analogues (-) were identified from the mangrove-derived fungus sp. GXIMD 03004, which was isolated from the leaves of mangrove L. collected from Beibu Gulf in China.

Transfer learning enables identification of multiple types of RNA modifications using nanopore direct RNA sequencing.

Nanopore direct RNA sequencing (DRS) has emerged as a powerful tool for RNA modification identification. However, concurrently detecting multiple types of modifications in a single DRS sample remains a challenge. Here, we develop TandemMod, a transferable deep learning framework capable of detecting multiple types of RNA modifications in single DRS data.

Chromosomal-level genome assembly and annotation of the tropical sea cucumber Holothuria scabra.

Holothuria scabra, a commercially valuable yet ecologically vulnerable tropical holothuroid, has experienced a severe decline in its wild populations, especially in China. Genomic resources are crucial for the development of effective genomic breeding projects and stock conservation strategies to restore these natural populations. Until now, a high-quality, chromosome-level reference genome for H.

Silencing Ditylenchus destructor cathepsin L-like cysteine protease has negative pleiotropic effect on nematode ontogenesis.

Ditylenchus destructor is a migratory plant-parasitic nematode that severely harms many agriculturally important crops. The control of this pest is difficult, thus efficient strategies for its management in agricultural production are urgently required. Cathepsin L-like cysteine protease (CPL) is one important protease that has been shown to participate in various physiological and pathological processes.

Root hairs facilitate rice root penetration into compacted layers.

Compacted soil layers adversely affect rooting depth and access to deeper nutrient and water resources, thereby impacting climate resilience of crop production and global food security. Root hair plays well-known roles in facilitating water and nutrient acquisition. Here, we report that root hair also contributes to root penetration into compacted layers.

Long-term outcomes of endovascular therapy for right subclavian artery occlusive lesions: A multi-center experience.

ObjectiveTo review our multi-institutional experience with endovascular therapy for right subclavian artery occlusive disease and to evaluate the long-term outcomes.MethodsWe retrospectively evaluated all patients with right subclavian artery stenosis and occlusive disease who underwent endovascular therapy between March 2014 and September 2022 at two institutions. Patient baseline demographics, lesion characteristics, treatment strategies, and in-hospital and follow-up outcomes were prospectively collected and retrospectively analyzed.

Identification and characterization of the gene family in and the involvement of ScREM1.5e-1/-2 in SCMV infection on sugarcane.

Introduction: Remorins (REMs) are plant-specific membrane-associated proteins that play important roles in plant-pathogen interactions and environmental adaptations. Group I REMs are extensively involved in virus infection. However, little is known about the gene family in sugarcane ( spp.

Ethylene regulates auxin-mediated root gravitropic machinery and controls root angle in cereal crops.

Root angle is a critical factor in optimizing the acquisition of essential resources from different soil depths. The regulation of root angle relies on the auxin-mediated root gravitropism machinery. While the influence of ethylene on auxin levels is known, its specific role in governing root gravitropism and angle remains uncertain, particularly when Arabidopsis (Arabidopsis thaliana) core ethylene signaling mutants show no gravitropic defects.

MicroRNA sequencing analysis reveals immune responses in hepatopancreas of Fenneropenaeus penicillatus under white spot syndrome virus infection.

White Spot Disease is one of the most harmful diseases of the red tail shrimp, which can cause devastating economic losses due to the highest mortality up to 100% within a few days. MicroRNAs (miRNAs) are large class of small noncoding RNAs with the ability to post-transcriptionally repress the translation of target mRNAs. MiRNAs are considered to have a significant role in the innate immune response of crustaceans, particularly in relation to antiviral defense mechanisms.