pH-dependent response of soil microbial community and multifunctionality to long-term low and moderate mercury pollution.

Low and moderate concentrations represent the predominant forms of mercury pollution in contaminated regions. Nevertheless, the responses of soil microbial communities to these pollution levels are still poorly understood. Here, under field conditions, we evaluated the impact of long-term exposure to low and moderate Hg pollution (0.

Recent Progress of 2D Conductive Metal-Organic Frameworks in Advanced Energy Storage.

Advanced energy storage systems play a critical role in energy capture, storage, and release across applications like smart devices, electrified transportation, renewable energy, and green power grids. However, the development of energy storage devices with large capacity, long lifespan, and high power density is hindered by challenges related to electrochemically active materials. Traditional electrode materials-such as graphite, metal oxides, polymers, and simple composites-suffer from poor electrical conductivity, unstable structures, slow ionic diffusion, and limited active site utilization during charge-discharge cycles.

Real-time prediction of HFNC treatment failure in acute hypoxemic respiratory failure using machine learning.

Accurate and timely prediction of high-flow nasal cannula (HFNC) treatment failure in patients with acute hypoxemic respiratory failure (AHRF) can lower patient mortality. Previous studies have highlighted inconsistencies in the predictive performance of existing indices, such as ROX and mROX, which are limited by their reliance on oxygenation parameters alone. To address this, we developed a machine learning-based predictive model using temporal data from AHRF patients, aimed at facilitating quicker development of individualized treatment plans and intervention strategies for healthcare professionals.

Multiscale structure, physicochemical properties, and in vitro digestibility on complex of static magnetic field modified rice starch with quercetin.

This study investigated the effects of static magnetic field-quercetin synergistic modification on the multiscale structure (morphological, crystalline, short-range, and long-range ordered structure), physicochemical properties, and in vitro digestibility of rice starch. The results demonstrated that the synergistic treatment significantly improved starch solubility while reducing swelling power and viscosity. SEM revealed enhanced surface porosity, fissures, and decreased particle size.

Method for evaluating the stray-light suppression performance of an internally occulted reflecting coronagraph in the Lyman alpha band.

The Lyman alpha (Lyman- or ) radiation emitted by hydrogen is the strongest ultraviolet spectral line on the corona, which can provide important coronal information that is difficult to obtain at other wavelengths and of great significance to comprehensively study the origin of the corona. In order to observe the corona and provide space weather warning in time, the stray-light suppression performance with a field-of-view (FOV) of 2.5 ( stands for the mean solar radius) for coronagraphs should be suppressed to 10 ( is the mean brightness of the solar disk).

Soybean 7S globulin and rice proteins form network structures: A comprehensive study of rice dough and rice bread.

The lack of network structure in rice dough imposes limitations on the production of corresponding gluten-free (GF) food. This study investigated and evaluated the network structure constructed by the interaction of soybean 7S globulin (7S) with rice proteins (RPs), and the improvement of dough. These structural modifications were fully validated by the rice bread system.

Recent Advances in Processing Methods and Utilization of Hulless Barley and Its Nutritional Components: A Review.

As a dominant crop in the plateau, hulless barley (HB) occupies an important position in traditional diets due to its unique growth adaptability and nutrition characteristics. It has attracted increasing attention due to its excellent health characteristics, including antioxidant activity, blood glucose regulation, gastrointestinal health improvement, prevention of chronic diseases, and anti-fatigue effects. However, due to structural defects or substantial nutrient loss during processing and poor palatability of HB products, it is urgent to enhance the functional characteristics by modification methods.

Bone Regeneration and Morphologic Changes in Pediatric Iliac Donor Sites After Alveolar Cleft Bone Grafting: A 3D Digital Analysis.

Introduction: Autogenous iliac bone grafting is the gold standard for alveolar cleft repair, yet comprehensive studies on donor site regeneration remain limited. This study aimed to objectively evaluate iliac bone regeneration, volumetric changes, and patient outcomes using 3D digital technology.

Materials And Methods: A retrospective analysis included 16 pediatric patients (8-12 y) undergoing unilateral alveolar cleft repair.

Three-dimensional morphometric analysis of alar asymmetry in unilateral secondary cleft nasal deformity: implications for non-cleft alar reduction in surgical planning.

Preoperative surgical planning for alar reduction remains challenging due to the lack of objective references in traditional measurements. Therefore, this study aimed to objectively quantify preoperative bilateral alar symmetry using 3D best-fit alignment analysis, and to establish an evidence-based threshold for alar morphological deviation for alar reduction in secondary cleft rhinoplasty. 26 patients with unilateral secondary cleft nasal deformity were retrospectively assessed: 13 underwent secondary cleft rhinoplasty alone and 13 received concurrent alar reduction.

Identification of staphylococcus aureus spondylitis in patients with spinal infections using machine learning based on routine laboratory tests: a multicenter retrospective study.

Rapid etiological identification of Staphylococcus aureus (S. aureus) in spinal infections can be challenging, often delaying targeted therapy. We developed a machine learning model leveraging XGBoost to predict S.

Mining and characterization of novel peptides from soy protein hydrolysates that ameliorate insulin resistance based on molecular docking, molecular dynamics simulations and mechanism validation.

Inhibition of protein tyrosine phosphatase 1B (PTP1B) holds promise for ameliorating insulin resistance (IR). Through enzymatic bioconversion of soy protein-a major agro-industrial byproduct-we identified four PTP1B-inhibitory peptides (D-8-N, K-8-F, K-11-M, D-10-E) using cell hypoglycemic activity-guided purification and in silico screening. Molecular dynamics and docking suggested allosteric inhibition via hydrogen bonding, electrostatic interactions, and hydrophobic forces.

Osteogenesis rate and success of secondary alveolar bone grafting: A 3D volumetric prognostic value.

Background: Secondary alveolar bone grafting (SABG) is a critical intervention for restoring anatomical integrity and functional capacity in patients with alveolar clefts. Despite advancements in surgical techniques and imaging, the optimal indicator for postoperative outcome evaluation remains undefined.

Methods: In this retrospective study, 126 patients with unilateral alveolar clefts who underwent SABG between 2016 and 2023 were analyzed.

Research progress on rice starch retrogradation: Insights into mechanism, influencing factors, detection technology and regulatory approaches.

Rice is a vital staple food, with starch as its primary component, providing essential energy. However, starch retrogradation negatively impacts the sensory and storage quality of rice starch and its products, limiting their use and development. Although various factors influencing starch retrogradation are well-documented, there has been limited systematic research on its mechanism and detection techniques.

Soliton wall and Au adatom-induced-to-isomerization promoting the formation of multiple pairs of chiral isomers of methylcyano-functionalized molecules.

The modulation of molecular adsorption configurations on surfaces, particularly regarding chirality and-isomerization, holds significant importance for interfacial molecular science and the construction of functional nanostructures. However, limited studies have focused on the formation of multiple chiral isomer pairs from monomolecular species and the exploration of more strategies for stimulating-isomerization. Herein, we characterize chiral behavior of methylcyano-functionalized molecules upon adsorption on Au(111) and elucidate theirtoisomerization.

Colon Dialysis with Yishen Decoction Improves Autophagy Disorder in Intestinal Mucosal Epithelial Cells of Chronic Renal Failure by Regulating SIRT1 Pathway.

Objective: To explore the mechanism of colon dialysis with Yishen Decoction (YS) in improving the autophagy disorder of intestinal epithelial cells in chronic renal failure (CRF) in vivo and in vitro.

Methods: Thirty male SD rats were randomly divided into normal, CRF, and colonic dialysis with YS groups by a random number table method (n=10). The CRF model was established by orally gavage of adenine 200 mg/(kg•d) for 4 weeks.

Spatiotemporal variations in Pearl River plume dispersion over the last decade based on VIIRS-derived sea surface salinity.

A river plume indicates the dispersion and transport path of pollutants from runoff, monitoring the spatiotemporal variation of river plume distribution from space is crucial for marine environmental governance. This study focuses on the Pearl River Plume (PRP), and takes the Pearl River Delta coastal waters, China as study area. We developed a machine learning-based sea surface salinity (SSS) estimation algorithm for the Visible Infrared Imaging Radiometer Suite (VIIRS) on-board the Suomi National Polar-orbiting Partnership satellite (SNPP), leveraging extensive field-measured SSS data from the study area.

Polyamine Metabolism Promotes the Progression of Thyroid Carcinoma by Regulating the Immune Phenotype of Tumor Associated Macrophages.

Polyamine metabolism is a key regulator of cellular proliferation and immune modulation, and its dysregulation is implicated in multiple carcinoma pathogenesis. Macrophages also greatly influence tumor progression by regulating the immune microenvironment. However, the role of polyamine metabolism in thyroid cancer macrophages remains understudied.

Experimental Study on the Effects of Thermal Cycling and Ultraviolet Irradiation on Stable Characteristics of Carbon Fiber/Bismaleimide Polymer Composite Shells.

Carbon fiber/epoxy composites are widely used in aerospace due to their strength and ease of fab weatherrication, but they suffer from glass transition at high temperatures. In contrast, carbon fiber/bismaleimide composites exhibit superior thermal stability, irradiation resistance, and toughness. This study investigates the effects of thermal cycling and UV irradiation on carbon fiber/bismaleimide composite shells.

Development of a 5-Year Risk Prediction Model for Transition From Prediabetes to Diabetes Using Machine Learning: Retrospective Cohort Study.

Background: Diabetes has emerged as a critical global public health crisis. Prediabetes, as the transitional phase with 5%-10% annual progression to diabetes, offers a critical window for intervention. The lack of a 5-year risk prediction model for diabetes progression among Chinese individuals with prediabetes limits clinical decision-making support.

Direct mechanical thrombectomy vs. intravenous alteplase plus mechanical thrombectomy in acute ischemic stroke with anterior circulation tandem occlusions.

Background And Purpose: Tandem occlusion is a significant risk factor for poor outcomes following intravenous thrombolysis. The necessity of bridging therapy [intravenous thrombolysis prior to mechanical thrombectomy (MT)] for patients with tandem occlusion remains controversial. This study assessed the safety and efficacy of direct MT vs.

Human umbilical cord mesenchymal stem cells improve the pregnancy outcomes of preeclampsia rats via inducing placental angiogenesis.

Background: Preeclampsia is considered to be a serious complication unique to pregnancy caused by placental dysplasia. Although interventions such as antihypertensive drugs and magnesium sulfate can partially mitigate maternal risk, the ultimate remedy remains delivery. In recent years, mesenchymal stem cells (MSCs) have become promising therapeutic approach in the treatment of ischemic diseases.

Secondary Alveolar Bone Grafting in the Mixed Dentition Phase: Patients of Younger Age Associated With Enhanced Osteogenesis and Midfacial Skeletal Symmetry.

Introduction: Alveolar bone grafting during the mixed dentition period is a common treatment, but the optimal surgical timing remains unclear. This study aims to evaluate how age influences the outcomes of secondary alveolar cleft repair, focusing on bone formation and midfacial symmetry.

Materials And Methods: This study retrospectively analyzed patients who underwent autologous iliac cancellous bone grafting for alveolar cleft repair from January 2019 to August 2023.

Transport of Volatiles in Agglutinates from Lunar Regolith of Chang'e-5 Mission.

Agglutinate particles, an important component resulting from micrometeoroids impacts, account for about 13.4% to 84.7% of the volume of lunar regolith depending on its maturity.