Discordance between knee and hand-wrist bone age in adolescents: implications for skeletal maturity assessment and its association with thyroid-stimulating hormone levels.

Background: Hand-wrist radiographs may not fully reflect skeletal bone age (BA) during mid-to-late puberty. Knee magnetic resonance imaging (MRI), a non-radiative imaging technique, may provide detailed evaluation of the lower limbs.

Objective: To validate the San Diego MRI-based knee BA atlas in a Chinese adolescent cohort presenting with growth deceleration, evaluate the concordance between knee and hand-wrist BA, and explore factors influencing potential discrepancies.

Growth plate continuity on knee MRI predicts growth hormone effect in mid-to-late puberty with idiopathic short stature.

Purpose: To evaluate the efficacy and cost-effectiveness of recombinant human growth hormone (rhGH) therapy in adolescents with idiopathic short stature during mid-to-late puberty, using knee MRI to predict therapeutic response.

Methods: This one-year prospective cohort study included 50 idiopathic short stature adolescents and 100 healthy controls. Participants underwent knee MRI to classify growth plates into "continuous" and "discontinuous" subgroups.

Global, regional, and national burden and trends of eating disorders among women of childbearing age from 1990 to 2021: Insights from the global burden of disease study 2021.

Objective: Eating disorders (ED) pose a significant global health challenge for women of childbearing age (WCBA). This study aims to systematically evaluate the global disease burden and temporal trends of eating disorders in this vulnerable population.

Methods: This study utilized Global Burden of Diseases (GBD) data to assess the burden and trends in prevalence, incidence, and Disability-Adjusted Life Years (DALYs) rates of eating disorders, estimating percentage changes and annual percentage changes (EAPC).

24-Hour Physical Activity Intensity and Energy Intake Trajectories and Their Associations with All-Cause Mortality: A Population-Based Cohort Study.

Diet and physical activity together affect health as important components of energy intake and energy expenditure, but few studies have considered the temporal interaction effect between them. Therefore, this study aimed to identify real-world 24-h physical activity intensity and energy intake trajectories and explore their associations with all-cause mortality. A total of 6389 participants from the 2003-2006 annual survey of the National Health and Nutrition Examination Survey (NHANES) were involved as baseline data in this study.

The Association of Healthy Eating Index and Sleep Disorders: A Meta-Analysis.

Background: Sleep disorders are problems that include both the quality and the time of sleep. It is related to overall diet quality, and dietary patterns also affect the quantity and quality of sleep in humans. The Healthy Eating Index (HEI) is widely used to assess the quality of diet.

Association of weekend catch-up sleep, sleep durations and cardiometabolic multimorbidity: Based on NHANES.

Background: Cardiometabolic multimorbidity (CMM) is defined as the coexistence of two or more cardiometabolic diseases, including hypertension, diabetes, stroke, and cardiovascular disease. Weekend catch-up sleep (WCS) is an effective repayment of sleep debt, and the association between WCS and CMM, and between WCS and CMM under the influence of average sleep duration, weekday sleep duration, and weekend sleep duration is unknown. The aim of this study was to determine the association between WCS and CMM and their association under different sleep durations.

Deep Anatomical Federated Network (Dafne): An Open Client-Server Framework for Continuous, Collaborative Improvement of Deep Learning-based Medical Image Segmentation.

Purpose To present and evaluate Dafne (deep anatomical federated network), a freely available decentralized, collaborative deep learning system for the semantic segmentation of radiologic images through federated incremental learning. Materials and Methods Dafne is free software with a client-server architecture. The client side is an advanced user interface that applies the deep learning models stored on the server to the user's data and allows the user to check and refine the prediction.

Muscle mass mediates the association between dietary diversity and mortality among the older adults: A prospective cohort study.

Aims: The association between dietary diversity and increased mortality risk is well-documented. However, it remains unclear whether and to what extent dietary diversity affects mortality through appendicular skeletal muscle mass (ASM). Therefore, we assessed whether ASM mediated the association between dietary diversity and mortality.

Arbuscular mycorrhizal fungi communities and promoting the growth of alfalfa in saline ecosystems of northern China.

Arbuscular mycorrhizal fungi (AMF) are universally distributed in soils, including saline soils, and can form mycorrhizal symbiosis with the vast majority of higher plants. This symbiosis can reduce soil salinity and influence plant growth and development by improving nutrient uptake, increasing plant antioxidant enzyme activity, and regulating hormone levels. In this study, rhizosphere soil from eight plants in the Songnen saline-alkaline grassland was used to isolate, characterize, and screen the indigenous advantageous AMF.

Clinical characteristics and biomarkers feature analysis using a proteomics platform in young patients with acute coronary syndrome.

Background: Acute coronary syndrome (ACS) is a leading cause of morbidity and mortality worldwide. In recent years, ACS has been reported to be associated with age, and the incidence has become more common in younger patients. Previous studies have identified various risk factors that contribute to the stratification of ACS patients.

Children's bone age development is delayed with increasing altitude: a multicentre study.

Objectives: To investigate the bone age (BA) characteristics of children living in high-altitude regions and determine the impact of altitude on the development of BA.

Methods: From June 2014 to July 2022, 1318 children with left-hand-wrist radiographs were retrospectively enrolled from 3 different geographical altitudes (Beijing 43.5 m above sea level [asl], Lhasa 3650 m asl, and Nagqu 4500 m asl).

Body mass index mediates the association between four dietary indices and phenotypic age acceleration in adults: a cross-sectional study.

: Diet and body mass index (BMI) are widely recognized as being closely associated with aging. However, it remains unclear which dietary indices are associated with aging, and the extent to which BMI mediates the relationship between diet and aging. Therefore, this study investigates the mediating role of BMI in the association between various dietary indices and phenotypic age acceleration (PhenoAgeAccel).

Effects of the fermentation quality and microbial community of waxy maize mixed with fodder soybean silage.

Waxy maize ( L. sinensis Kulesh) is highly regarded for its high nutritional content and unique taste. Although the stalks and leaves contain high carbohydrate levels after ear harvesting, inadequate crude protein (CP) limits the utilization and promotion of waxy maize silage in animal husbandry.

The association between multiple trajectories of macronutrient intake and the risk of new-onset diabetes in Chinese adults.

Background: The association between macronutrient intake and diabetes is unclear. We used data from the China Health and Nutrition Survey to explore the association between macronutrient intake trajectories and diabetes risk in this study.

Methods: We included 6755 participants who did not have diabetes at baseline and participated in at least three surveys.

LINC317.5 as a novel biomarker for hypertriglyceridemia in normal glucose metabolism.

The global rise in prediabetes and diabetes, with type 2 diabetes (T2DM) being predominant, highlights the association between T2DM and hypertriglyceridemia (HTG). Patients with both abnormal glucose levels and HTG require increased attention due to higher risks of complications and mortality. Therefore, this study aimed to find the key long non-coding RNA (lncRNA) of HTG in the abnormal glucose metabolism patients.

The association between oxidative balance score and frailty in adults across a wide age spectrum: NHANES 2007-2018.

: Frailty has been one of the most serious global public health challenges we will ever face. Oxidative stress is associated with the pathogenesis of frailty, and may be accurately reflected by the oxidative balance score (OBS). However, there have been no studies examining the effect of OBS on frailty.

Association of Physical Activity with Phenotypic Age among Populations with Different Breakfast Habits.

Background: The global aging situation has reached a serious stage, and healthy lifestyles, like regular physical activity and eating breakfast, could slow the process. Phenotypic age (PhenoAge) is regarded as a novel measure of aging. Therefore, our study aimed to quantify the impact of physical activity and eating breakfast on aging via PhenoAge and phenotypic age acceleration (PhenoAgeAccel).

An artificial intelligence-based bone age assessment model for Han and Tibetan children.

Manual bone age assessment (BAA) is associated with longer interpretation time and higher cost and variability, thus posing challenges in areas with restricted medical facilities, such as the high-altitude Tibetan Plateau. The application of artificial intelligence (AI) for automating BAA could facilitate resolving this issue. This study aimed to develop an AI-based BAA model for Han and Tibetan children.

The association between vitamin K intake and dyslipidemia in US adults: the mediating effect of insulin resistance.

: Dyslipidemia is one of the most common chronic diseases, and is associated with insulin resistance (IR) and inadequate vitamin K intake. We aimed to explore the association between IR, vitamin K intake, and dyslipidemia, and further to explore the mediating role of IR. : 12 860 participants from the National Health and Nutrition Examination Survey (NHANES) from 2001 to 2018 were included in this study.