Comparing EQ-5D-3L and EQ-5D-5L performance in common cancers: suggestions for instrument choosing.

Purpose: To compare the performance of three-level EuroQol five-dimensions (EQ-5D-3L) and five-level EuroQol five-dimensions (EQ-5D-5L) among common cancer patients in urban China.

Methods: A hospital-based cross-sectional survey was conducted in three provinces from 2016 to 2018 in urban China. Patients with breast cancer, colorectal cancer, or lung cancer were recruited to complete the EQ-5D-3L and EQ-5D-5L questionnaires.

Evaluation of the photodynamic efficacy and effects of haematoporphyrin monomethyl ether on Trichophyton rubrum microconidia in vitro.

Background: Current available treatment modes against dermatophytoses are often tedious and sometimes unsatisfactory. As an emerging and promising approach, antimicrobial photodynamic therapy (aPDT) attracts much attention in the treatment of superficial or localised infections.

Objectives: This work investigated the photodynamic efficacy and effects of haematoporphyrin monomethyl ether (HMME) on microconidia of Trichophyton rubrum in vitro.

Kohn-Luttinger Mechanism Driven Exotic Topological Superconductivity on the Penrose Lattice.

The Kohn-Luttinger mechanism for unconventional superconductivity (SC) driven by weak repulsive electron-electron interactions on a periodic lattice is generalized to the quasicrystal (QC) via a real-space perturbative approach. The repulsive Hubbard model on the Penrose lattice is studied as an example, on which a classification of the pairing symmetries is performed and a pairing phase diagram is obtained. Two remarkable properties of these pairing states are revealed, due to the combination of the presence of the point-group symmetry and the lack of translation symmetry on this lattice.

The diagnostic value of circulating miR-532-5p in patients with asymptomatic carotid artery stenosis and its predictive significance for the occurrence of cerebral ischaemic events.

Introduction: Circulating microRNAs (miRNAs) are widely identified as promising and novel biomarkers for the diagnosis of human diseases. This study investigated the clinical value of miR-532-5p for asymptomatic carotid artery stenosis (CAS) patients and detected its predictive value for the occurrence of future cerebral ischaemic events (CIE).

Material And Methods: Serum expression of miR-532-5p was measured using qRT-PCR.

[Characteristics of Cd, As, and Pb in Soil and Wheat Grains and Health Risk Assessment of Grain-Cd/As/Pb on the Field Scale].

In recent years, heavy metal pollution in farmlands has become increasingly serious because of human activities such as metal smelting, sewage irrigation, and road traffic in China. A field survey was conducted to investigate characteristics of Cd, As, and Pb in soil and wheat grains and assess the health risk of grain-Cd/As/Pb to humans on the fields scale. The farmland was influenced by smelter and sewage irrigation in the attitude and by road traffic in the horizon.

Facile synthesis of CoMnO/C nanocages as an efficient sulfur host for lithium-sulfur batteries with enhanced rate performance.

Capacity reduction mainly caused by the shuttle effect and low conductivity restricts the commercial application of lithium-sulfur batteries (LSBs). Herein, we developed a method to overcome these two obstacles synchronously by designing nitrogenous carbon decorated hollow Co3-xMnxO4/C nanocages as hosts of sulfur. These hosts were derived from manganese doped ZIF-67 by a facile sintering method, which provided polar surface to anchor lithium polysulfides and considerable electronic conductivity.

A Combined Ultrasonic Backscatter Parameter for Bone Status Evaluation in Neonates.

Metabolic bone disease (MBD) is one of the major complications of prematurity. Ultrasonic backscatter technique has the potential to be a portable and noninvasive method for early diagnosis of MBD. This study firstly applied CAS to neonates, which was defined as a linear combination of the apparent integrated backscatter coefficient (AIB) and spectral centroid shift (SCS).

LINC00460 accelerates progression of ovarian cancer by activating transcriptional factor ZNF703.

Potential function of LINC00460 in the progression of ovarian cancer (OC) and its underlying mechanism were studied. LINC00460 level in OC tissues and normal ovarian tissues was detected by quantitative real-time polymerase chain reaction (qRT-PCR). Correlation between LINC00460 level with tumor stage, tumor size and pathological subtypes of OC was analyzed.

Numerical Evaluation of the Influence of Skull Heterogeneity on Transcranial Ultrasonic Focusing.

In transcranial penetration, ultrasound undergoes refraction, diffraction, multi-reflection, and mode conversion. These factors lead to phase aberration and waveform distortion, which impede the realization of transcranial ultrasonic imaging and therapy. Ray tracing has been used to correct the phase aberration and is computationally more efficient than traditional full-wave simulation.

Comparative Evaluation of Participation and Diagnostic Yield of Colonoscopy vs Fecal Immunochemical Test vs Risk-Adapted Screening in Colorectal Cancer Screening: Interim Analysis of a Multicenter Randomized Controlled Trial (TARGET-C).

Introduction: In colorectal cancer screening, implementing risk-adapted screening might be more effective than traditional screening strategies. We aimed to compare the effectiveness of a risk-adapted screening strategy with colonoscopy and fecal immunochemical test (FIT) in colorectal cancer screening.

Methods: A randomized controlled trial was conducted in 6 centers in China since May 2018.

Mesoporous Cu-CuO@TiO heterojunction photocatalysts derived from metal-organic frameworks.

This study reveals a unique Cu-CuO@TiO heterojunction photocatalyst obtained with metal-organic framework as the precursor, which can be utilized in dye photodegradation under visible light irradiation. The composition, structure, morphology, porosity, optical properties and photocatalytic performance of the obtained catalysts were all investigated in detail. The Cu-CuO@TiO nanocomposite is composed of lamellar Cu-CuO microspheres embedded by numerous TiO nanoparticles.

The effects of aloe emodin-mediated antimicrobial photodynamic therapy on drug-sensitive and resistant Candida albicans.

The extensive and repetitive use of antifungal drugs has led to the development of drug-resistant Candida albicans. Antimicrobial photodynamic therapy (aPDT) has received considerable attention as an emerging and promising approach to combat drug-resistant microbes. This study evaluated the photodynamic effects mediated by aloe emodin (AE), a natural compound isolated from Aloe vera and Rheum palmatum, on azole-sensitive and azole-resistant C.

Extreme weather events recorded by daily to hourly resolution biogeochemical proxies of marine giant clam shells.

Paleoclimate research has built a framework for Earth's climate changes over the past 65 million years or even longer. However, our knowledge of weather-timescale extreme events (WEEs, also named paleoweather), which usually occur over several days or hours, under different climate regimes is almost blank because current paleoclimatic records rarely provide information with temporal resolution shorter than monthly scale. Here we show that giant clam shells ( spp.

Safety of OnabotulinumtoxinA with Concomitant Antithrombotic Therapy in Patients with Muscle Spasticity: A Retrospective Pooled Analysis of Randomized Double-Blind Studies.

Background: OnabotulinumtoxinA is approved as a treatment across multiple indications. For the treatment of spasticity, onabotulinumtoxinA is injected directly into affected muscles. Intramuscular injections may result in local bleeding and related complications, especially in patients receiving anticoagulant therapy.

compound heterozygous mutations associated with autophagic impairment cause cerebral infarction in Pompe disease.

Clinical manifestations of the late-onset adult Pompe disease (glycogen storage disease type II) are heterogeneous. To identify genetic defects of a special patient population with cerebrovascular involvement as the main symptom, we performed whole-genome sequencing (WGS) analysis on a consanguineous Chinese family of total eight members including two Pompe siblings both had cerebral infarction. Two novel compound heterozygous variants were found in GAA gene: c.

A Study on Prevalence and Characterization of in Ready-to-Eat Foods in China.

is widely distributed in different food products and can cause a variety of symptoms associated with food poisoning. Since ready-to-eat (RTE) foods are not commonly sterilized by heat treatment before consumption, contamination may cause severe food safety problems. In this study, we investigated the prevalence of in RTE food samples from different regions of China and evaluated the levels of bacterial contamination, antibiotic resistance, virulence gene distribution, and genetic polymorphisms of these isolates.

A novel control strategy for the partial nitrification and anammox process (PN/A) of immobilized particles: Using salinity as a factor.

The impact of the addition of salinity on partial nitrification and anammox (PN/A) was investigated in this study. The sludge was immobilized by polyethylene glycol (PEG)-modified polyvinyl alcohol (PVA)-sodium alginate (SA) immobilization technology, and the effective diffusion coefficient (D) of the immobilized particles was measured to be 0.313 × 10 m·s, indicating that the system has excellent mass transfer performance.

CD13-specific ligand facilitates Xanthatin nanomedicine targeting dendritic cells for therapy of refractory allergic rhinitis.

Relapse in Allergic Rhinitis (AR) is triggered by various unclear mechanisms. Xanthium strumarium L. as a traditional folk medicine can inhibit inflammatory responses through multiple mechanisms.

Nodal Line Spin-Gapless Semimetals and High-Quality Candidate Materials.

Spin-gapless semimetals (SGSMs), which generate 100% spin polarization, are viewed as promising semi-half-metals in spintronics with high speed and low consumption. We propose and characterize a new Z_{2} class of topological nodal line (TNL) in SGSMs. The proposed TNLSGSMs are protected by space-time inversion symmetry or glide mirror symmetry with two-dimensional (2D) fully spin-polarized nearly flat surface states.

Antimicrobial photodynamic therapy against multidrug-resistant Acinetobacter baumannii clinical isolates mediated by aloe-emodin: An in vitro study.

Background And Aim: Antimicrobial photodynamic therapy (aPDT) has received considerable attention as an emerging and promising approach for treating superficial infections. The aim of this study was to investigate aPDT mediated by aloe emodin (AE), a natural compound isolated from Aloe vera and Rheum palmatum, against multidrug-resistant (MDR) Acinetobacter baumannii clinical isolates in vitro.

Methods: The photodynamic inactivation (PDI) efficacies of AE on three MDR A.

[Rapid Cultivation of Anaerobic Ammonium Oxidation Granular Sludge and Inhibition Kinetics of Granular Sludge].

For the rapid cultivation of anaerobic ammonium oxidation (ANAMMOX) granular sludge (AGS), a small amount of flocculent ANAMMOX sludge (FAS) was taken as the research object, and a bio-flow separate ball was used as the filler in an up-flow anaerobic sludge bed (UASB) to rapidly begin ANAMMOX and to cultivate granular sludge. In addition, the substrate inhibition kinetic characteristics of the AGS were investigated by using the Haldane model. The results showed that start-up of the ANAMMOX was successfully achieved.

Spatiotemporal changes in vegetation coverage and its causes in China since the Chinese economic reform.

With the rapid development of the economy over 40 years since the initiation of Chinese economic reform, terrestrial ecosystems in China have undergone large-scale changes. In this study, we investigated vegetation dynamics in China and their relationships with climatic factors and anthropogenic drivers over 15 progressive periods of 18-32 years starting in 1982. This was accomplished by using the third-generation global satellite Advanced Very High Resolution Radiometer (AVHRR), Normalized Difference Vegetation Index (NDVI) dataset, night-time satellite data, and climate data.