Amino-Functionalized Lanthanide Metal-Organic Frameworks for Ratiometric Detection of Perfluorooctanoic Acid.

Perfluorooctanoic acid (PFOA) is a persistent organic pollutant with a global presence in water, air, and soil resources. Herein, a water-stable amine-functionalized lanthanide metal-organic framework () is utilized for ratiometric luminescence detection of PFOA. In the presence of PFOA, there is an increase in the emission intensity of the organic ligand, while the characteristic luminescence intensity of Eu ions decreases, accompanied by a distinct emission color change from red to blue.

Yttrium-90 selective internal radiation therapy for right hepatic malignancies: a clinical outcome study.

Background: Surgical resection offers long-term survival for liver malignancies, but insufficient future liver remnant (FLR) volume often precludes operability. This study evaluated yttrium-90 selective internal radiation therapy (Y-SIRT) for controlling right-liver tumors and inducing compensatory left-lobe hyperplasia.

Results: Thirty-seven patients (29 hepatocellular carcinomas, 2 intrahepatic cholangiocarcinoma, 6 liver metastasis of colorectal cancer) with right-liver tumors underwent Y-SIRT.

The coupling of methylation-sensitive restriction enzyme with recombinant polymerase amplification and lateral flow dipstick for the detection of (menstrual) blood stains.

Blood is a critical and frequently encountered type of evidence at forensic crime scenes. Its detection can provide valuable insights into the nature of a case and help refine investigative focus. The blood test strip is the most commonly used method for blood detection.

Observation of Coherent Perfect Acoustic Absorption at an Exceptional Point.

Non-Hermitian systems have recently shown new possibilities to manipulate wave scattering by exploiting loss, yet coherent perfect absorption at an exceptional point (CPA EP) remains elusive in acoustics. Here, we demonstrate it based on a two-channel waveguide with compact lossy resonators. We realize imbalanced losses crucial for CPA EP by using active components to independently modulate the non-Hermiticity.

Evaluative performance of TyG-ABSI versus traditional indices in relation to cardiovascular disease and mortality: evidence from the U.S. NHANES.

Background: Metabolic Syndrome (MetS) significantly increases the risk of cardiovascular disease (CVD), with central obesity and insulin resistance as major contributors. The TyG-ABSI index is a newly proposed composite measure that combines the TyG index and ABSI, aiming to assess both insulin resistance and central obesity simultaneously. Previous studies have shown that TyG-ABSI has potential in predicting cardiovascular mortality, but its applicability in MetS populations remains unclear.

Spatial distribution, speciation, and release behavior of exogenous copper in soil aggregates: The role of aggregate structural reorganization.

Copper (Cu) contamination in soil poses serious environmental risks, impacting ecosystem health and groundwater quality. This study explored how soil aggregate structural reorganization influences the spatial distribution, chemical speciation, and release behavior of exogenous Cu. Aggregates with and without structural reorganization were prepared.

Global trends of early-onset Parkinson's disease from 1990 to 2021, and projections until to 2030: a systematic analysis of the global burden of disease study 2021.

Background: This study aims to evaluate the global, regional, and national trends in prevalence, incidence, mortality, and DALYs for early-onset Parkinson's disease (EOPD) from 1990 to 2021.

Methods: All data from the Global Burden of Diseases (GBD) 2021 were stratified by age, sex, location, and socio-demographic index (SDI). We performed comprehensive analysis to reveal trends for EOPD, utilizing average annual percentage change (AAPC), joinpoint regression analysis, health inequality analysis, frontier analysis, and Bayesian age-period-cohort (BAPC) models.

Ecological functions coupled with plasmid and phage-mediated dissemination drive the global prevalence of high-risk antimicrobial resistance genes in influent.

Antibiotic resistance genes (ARGs) in wastewater treatment plant (WWTP) influent pose potential global risk to public health. However, the spatiotemporal distribution of global influent ARGs, the highly prevalent core ARGs components, and their transmission mechanisms remain unclear. The resistance risk ranking integrating abundance, mobility, and pathogenicity in actual influent samples is still undefined.

A novel CO foam stabilizer based on natural polysaccharide psyllium seed gum: Experimental and molecular dynamics analysis.

The development of eco-friendly polymer foam stabilizers represents an emerging frontier in sustainable oil recovery, addressing the performance limitations and environmental persistence of traditional foam stabilizers under high-temperature and high-salinity conditions. This study proposes a novel use of natural psyllium seed gum (PG) as a foam stabilizer for CO foam flooding technology. A comparative analysis with polyacrylamide and xanthan gum demonstrates the effectiveness of PG in improving foam performance while elucidating its stabilization mechanism.

Prenatal genetic findings using karyotyping and chromosomal microarray analysis in the first-occurrence typical orofacial clefts.

Background: Orofacial clefts (OFCs), including cleft lip (CL), cleft palate (CP), and cleft lip and palate (CLP), are among the most common congenital anomalies. Prenatal genetic evaluation plays a critical role in guiding pregnancy management. This study aimed to evaluate genetic findings and pregnancy outcomes in first-occurrence fetal OFCs using conventional karyotyping and SNP array analysis.

Preferred screw placement area identified by imaging based quadrant and heatmap analysis for long screw fixation in Ogawa I coracoid process fractures.

Ogawa I coracoid process fractures are relatively rare. Surgical fixation requires precise determination of the screw length and direction to avoid iatrogenic injuries. Identifying the preferred screw placement area (PSPA) through imaging techniques is crucial for enhancing surgical safety and stability.

Genes associated with calcium signaling have promising diagnostic potential for gastric cancer.

Background: Gastric cancer (GC) represents a considerable health risk, characterized by a poor 5-year survival rate of approximately 8%. Using data from The Cancer Genome Atlas (TCGA), this study investigated the function of calcium signaling-related genes in the context of GC.

Methods: The RNA sequencing data and clinical characteristic data of GC patients were retrieved from TCGA database.

Effects of blood flow restriction combined with high-load training on muscle strength and sports performance in athletes: a systematic review and meta-analysis.

Objective: This study aims to present updated convergent analyses and data following systematic review and meta-analysis protocols to determine the effects of high-load resistance training (HL-RT) combined with blood flow restriction (BFR) on athletes' physiological adaptations (muscle strength and body composition) and athletic performance (power, speed, and endurance).

Methods: A systematic literature search was conducted using Boolean operators with keyword combinations in PubMed, Web of Science, and Embase for studies published up to February 2025. Methodological quality was assessed via the Cochrane Risk of Bias tool.

Redox regulation for sustainable water purification and risk management.

Sustainable detoxification and advanced treatment of toxic organic pollutants (TOPs) in wastewater are essential for water reclamation and ecosystem security. Although biological treatment is a low-carbon and eco-friendly approach for TOPs degradation, its effectiveness is often limited by the high toxicity and recalcitrance of TOPs. Oxidative and reductive reactions can degrade TOPs according to their intrinsic redox potentials.

MLAD: A Multi-Task Learning Framework for Anomaly Detection.

Anomaly detection in multivariate time series is a critical task across a range of real-world domains, such as industrial automation and the internet of things. These environments are generally monitored by various types of sensors that produce complex, high-dimensional time-series data with intricate cross-sensor dependencies. While existing methods often utilize sequence modeling or graph neural networks to capture global sensor relationships, they typically treat all sensors uniformly-potentially overlooking the benefit of grouping sensors with similar temporal patterns.

Defining Multi-Trait Breeding Objectives and Selection Indexes to Develop More Efficient Breeding Programs for Superfine Wool Sheep.

This study aimed to develop an optimized breeding program for the Alpine Merino sheep superfine strain by defining breeding objectives and establishing a multi-trait selection index. Using phenotypic and genetic (co)variance components of wool and growth traits, we identified six key breeding objectives: average fiber diameter (AFD), clean fleece weight (CFW), staple strength (SS), staple length (YSL), yearling weight (YWT), and weaning weight (WWT), with economic weights of 48, 48.5, 2, 12, 2.

Utilizing Distillation Curve and Refractive Index to Predict Property of Hydrocarbon Mixtures.

In this study, the property prediction models for density, surface tension, kinematic viscosity, dynamic viscosity, and flash point of diesel were developed by the feedforward neural network method utilizing the fuel distillation curve (T-T) as light and heavy composition distribution characteristics and the refractive index as the average composition characteristic. The applicability of the method across hydrocarbon mixtures of diesel and gasoline-kerosene-diesel fractions was explored. 92 surrogate diesel samples, ranging from binary to septenary mixtures, were prepared, and their refractive index, distillation curve, density, flash point, and surface tension were measured.

Regulating community redox metabolism for systematic mitigation of antibiotic chemical and biological risks.

The evolution of antimicrobial resistance (AMR) during antibiotic biological treatment is an unavoidable focus. However, little is known about how to regulate the systematic mitigation pathways for antibiotic chemical and biological risks. Here, we explore micro-aeration coupled with electrostimulation to regulate community redox metabolism, ultimately enhancing both the biodegradation of sulfamethoxazole (SMX) and the mitigation of antibiotic resistance genes (ARGs).

Prenucleation Cluster Effects on Colloidal CdSe Semiconductor Samples in Dispersion at Room Temperature.

The possible presence of prenucleation clusters (PNCs) in samples of colloidal semiconductor quantum dots (QDs) remains largely unknown. Using CdSe QDs as a model system, It is shown for the first time that samples from both heating-up and hot-injection approaches may contain the PNC. When a sample is dispersed in cyclohexane (CH) or toluene (Tol) at 25 °C, the nucleation and growth (N/G) of small QDs takes place.

Feasibility, efficacy, and safety of ventral caudal artery access for transarterial chemoembolization in a rat hepatocellular carcinoma model.

Purpose: Investigate the feasibility, efficacy, and safety of ventral caudal artery (VCA) approach for transarterial chemoembolization (TACE) in an orthotopic hepatocellular carcinoma (HCC) rat model.

Methods: Sixteen orthotopically established tumor-bearing Sprague-Dawley rats were divided into two groups of eight each: drug-eluting bead transarterial chemoembolization (DEB-TACE) group and normal saline (NS) group. VCA was approached for transarterial procedures.

SREBP-2 promotes cancer progression through the mevalonate-Akt pathway in non-small cell lung cancer.

Sterol regulatory element-binding protein-2 (SREBP-2) is a transcriptional factor, which mainly regulates cholesterogenesis-associated genes. The metabolism of cholesterol was found to be abnormal in non-small cell lung cancer (NSCLC). However, the clinical relevance of SREBP-2 in NSCLC has yet to be elucidated.

Laparoscopic liver parenchymal transection using CUSA versus harmonic scalpel: a protocol for a prospective randomized controlled trial.

Background: The harmonic scalpel (HS) and cavitron ultrasonic surgical aspirator (CUSA) are two common techniques for liver parenchymal transection (LPT). The second International Consensus Conference on laparoscopic liver resection (LLR) recommended the utilization of the HS for superficial layer LPT and the CUSA for deep layer LPT. Some centers currently employ the HS for deep-layer LPT.

Research on mechanical characteristics and key technology of integral intelligent lifting construction of large-span heavy steel box girder.

This paper aims to address the problems of aerial orientation control and safety in sudden extreme working conditions during the integral intelligent lifting of large-span heavy steel box girder. Based on the project of Xiaotun Bridge of Fuyi Expressway, a new integral lifting system and control method were proposed. To prevent extreme conditions during the lifting process, the mechanical properties of steel box girders in both synchronous and asynchronous integral lifting states were investigated using the finite element method.

Hepatic Artery Infusion Chemotherapy for Hepatocellular Carcinoma: Clinical Advancements.

Intermediate- and advanced-stage hepatocellular carcinoma (HCC) continues to present significant therapeutic challenges. Hepatic artery infusion chemotherapy (HAIC), a well-established locoregional treatment for unresectable HCC, has recently demonstrated promising clinical outcomes both as monotherapy and in combination with systemic therapies. This comprehensive review examines recent clinical advances in HAIC for HCC, with particular emphasis on evolving treatment regimens and their therapeutic efficacy.