An RFH-NPT-based nomogram for predicting the long-term survival of liver cirrhosis patients: a multicenter study.

Background And Aims: The Royal Free Hospital-Nutritional Prioritizing Tool (RFH-NPT) identifies nutritional risk in patients with liver disease, an important factor in cirrhosis outcomes. Recognizing the gap in existing prognostic models, which often overlook malnutrition, we developed and validated an RFH-NPT-based model for predicting outcomes of patients with cirrhosis.

Methods: This study included inpatients with cirrhosis from a single center between February and July 2016 (training cohort) and patients from six other medical centers admitted between December 2011 and May 2022 (validation cohort).

Association between albumin-bilirubin score and sarcopenia in middle-aged Americans: a cross-sectional study.

Background: The albumin-bilirubin (ALBI) score is a novel index for assessing liver function, integrating albumin and bilirubin levels to provide a comprehensive evaluation of a patient's overall health. Despite its utility, there is a paucity of research exploring the relationship between ALBI scores and sarcopenia in the existing literature, and studies on sarcopenia prevalence in middle-aged adults are also scarce. This study aims to investigate the association between ALBI scores and the prevalence of sarcopenia among middle-aged adults in the United States.

[Clinical efficacy of autologous apheresis platelet-rich plasma combined with adjustable titanium plate fixation in the treatment of Rockwood type â…¢ acromioclavicular joint dislocation].

Objective: To explore clinical efficacy of autologous platelet-rich plasma(PRP) in treating Rockwood type â…¢ acromioclavicular dislocation.

Methods: From January 2019 to July 2021, 32 patients with Rockwood type â…¢ acromioclavicular dislocation were treated with minimally invasive adjustable titanium plate internal fixation, and were divided into PRP group and control group according to whether PRP treatment was performed, with 16 patients in each group. In PRP group, there were 10 males and 6 females, aged from 28 to 47 years old with an average of (36.

Structural Optimization of Microfluidic Chips for Enhancing Droplet Manipulation and Observation via Electrodynamics Simulation.

Digital microfluidic chips (DMCs) have shown huge potential for biochemical analysis applications due to their excellent droplet manipulation capabilities. The driving force is a critical factor for characterizing and optimizing the performance of droplet manipulation. Conducting numerical analysis of the driving force is essential for DMC design, as it helps optimize the structural parameters.

Arched microfluidic channel for the promotion of axonal growth performance.

Uniformly distributed fluid shear stress can promote axonal growth, aiding in the efficient construction of functional neural interfaces. However, challenges remain in the construction of the micro-scale environment with a uniform fluidic stress distribution. In this study, we designed and fabricated a microfluidic chip with arched-section microfluidic channels (AMCs) to increase primary cortical neuron growth rate and terminal number by constructing a uniform-stress-distributed environment.

TPP-Based Microfluidic Chip Design and Fabrication Method for Optimized Nerve Cells Directed Growth.

Microfluidic chips offer high customizability and excellent biocompatibility, holding important promise for the precise control of biological growth at the microscale. However, the microfluidic chips employed in the studies of regulating cell growth are typically fabricated through 2D photolithography. This approach partially restricts the diversity of cell growth platform designs and manufacturing efficiency.

Enhancing the Electrical Conductivity and Strength of PET by Single-Wall Carbon Nanotube Film Coating.

Single-wall carbon nanotubes (SWCNTs) with excellent physicochemical properties are considered a promising candidate for the electrical and mechanical reinforcements of polymers. However, the poor dispersion of SWCNTs in plastics seriously limits their application and their achieved performance enhancement. Here, we coat a freestanding, highly conductive SWCNT film onto the surface of a polyethylene terephthalate (PET) film by a hot-pressing method.

Single-Walled Carbon Nanotube/Copper Core-Shell Fibers with a High Specific Electrical Conductivity.

Carbon nanotube (CNT)/Cu core-shell fibers are a promising material for lightweight conductors due to their higher conductivity than pure CNT fibers and lower density than traditional Cu wires. However, the electrical properties of the hybrid fiber have been unsatisfactory, mainly because of the weak CNT-Cu interfacial interaction. Here we report the fabrication of a single-walled CNT (SWCNT)/Cu core-shell fiber that outperforms commercial Cu wires in terms of specific electrical conductivity and current carrying capacity.

Defect-Induced Efficient Heteroepitaxial Growth of Single-Wall Carbon Nanotubes @ Hexagonal Boron Nitride Films.

Carbon nanotube-based derivatives have attracted considerable research interest due to their unique structure and fascinating physicochemical properties. However, the controlled growth mechanism of these derivatives remains unclear, and the synthesis efficiency is low. Herein, we proposed a defect-induced strategy for the efficient heteroepitaxial growth of single-wall carbon nanotubes (SWCNTs)@hexagonal boron nitride (h-BN) films.

The Effectiveness of Transcranial Stimulation in Improving Swallowing Outcomes in Adults with Poststroke Dysphagia: A Systematic Review and Meta-analysis.

Transcranial stimulation has been proposed as an alternative rehabilitation therapy for adults with post-stroke dysphagia (PSD). This systematic review sought to determine the effectiveness of transcranial stimulation in patients with post-stroke dysphagia to improve swallowing function. From inception to January 3, 2021, an extensive search was conducted in PubMed, EMBASE, Cochrane, CINAHL, and Scopus, Web of Science.

Rab21 Protein Is Degraded by Both the Ubiquitin-Proteasome Pathway and the Autophagy-Lysosome Pathway.

Rab21 is a GTPase protein that is functional in intracellular trafficking and involved in the pathologies of many diseases, such as Alzheimer's disease (AD), glioma, cancer, etc. Our previous work has reported its interaction with the catalytic subunit of gamma-secretase, PS1, and it regulates the activity of PS1 via transferring it from the early endosome to the late endosome/lysosome. However, it is still unknown how Rab21 protein itself is regulated.

High-efficient fabrication of core-shell-shell structured SiO@GdPO:Tb@SiO nanoparticles with improved luminescence.

SiO@GdPO:Tb@SiO nanoparticles with core-shell-shell structure were successfully synthesized by a cheap silane coupling agent grafting method at room temperature. This method not only homogeneously coated rare-earth phosphate nanoparticles on the surface of silica spheres but also saved the use of rare-earth resources. The obtained nanoparticles consisted of SiO core with a diameter of approximately 210 nm, GdPO:Tb intermediate shell with thickness of approximately 7 nm, and SiO outer shell with thickness of approximately 20 nm.

Socioeconomic factors of industrial air pollutants in Zhejiang Province, China: Decoupling and Decomposition analysis.

In order to analyze and control air pollutant emissions effectively, on the basis of comprehensive consideration of three different pollution sources of industrial sulfur dioxide, industrial nitrogen oxides, and industrial smoke and dust, the Tapio decoupling model and LMDI decomposition model with six decomposition variables are constructed to compare the effects of socioeconomic factors on industrial air pollutant emissions in 11 cities in Zhejiang Province during 2006-2017. Then, a decoupling effort model is developed to analyze the effectiveness of the decoupling efforts taken at city level. This study found that (1) during the period of 2006-2017, the air pollutant emission reduction work in Zhejiang Province achieved remarkable results.

Controlled synthesis and luminescence properties of core-shell-shell structured SiO@AIPA-S-Si-Eu@SiO and SiO@AIPA-S-Si-Eu-phen@SiO nanocomposites.

Two novel core-shell structured SiO@AIPA-S-Si-Eu and SiO@AIPA-S-Si-Eu-phen nanocomposites have been synthesized by a bifunctional organic ligands ((HOOC)CHNHCONH(CH)Si(OCHCH)) (defined as AIPA-S-Si) connected with Eu ions and silica via covalent bond. And the corresponding core-shell-shell structured SiO@AIPA-S-Si-Eu@SiO and SiO@AIPA-S-Si-Eu-phen@SiO nanocomposites with enhanced luminescence have been synthesized by tetraethyl orthosilicate (TEOS) hydrolysis co-deposition method. The composition and micromorphology of the nanocomposites were characterized by means of Fourier-transform infrared spectroscopy (FT-IR), thermal gravimetric analysis (TG), X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy-dispersive X-ray spectrometry (EDX) and X-ray photoelectron spectroscopy (XPS).

Synthesis and photoluminescence properties of silica-modified SiO@ANA-Si-Tb@SiO, SiO@ANA-Si-Tb-L@SiO core-shell-shell nanostructured composites.

Three novel core-shell nanostructured composites SiO@ANA-Si-Tb, SiO@ANA-Si-Tb-L (L = second ligand) with SiO as the core and terbium organic complex as the shell were successfully synthesized. The core and shell were connected together by covalent bonds. The terbium ion was coordinated with organic ligand-forming terbium organic complex in the shell layer.

Luminescence Studies and Judd-Ofelt Analysis on SiO@LaPO:Eu@SiO Submicro-spheres with Different Size of Intermediate Shells.

The novel submicro-spheres SiO@LaPO:Eu@SiO with core-shell-shell structures were prepared by connecting the SiO submicro-spheres and the rare earth ions through an organosilane HOOCCHN(CONH(CH)Si(OCHCH) (MABA-Si). The as-prepared products were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), and infrared spectroscopy (IR). It is found that the intermediate shell of the submicro-spheres was composed by LaPO:Eu nanoparticles with the size of about 4, 5-7, or 15-34 nm.

Synthesis and Luminescence Properties of Core-Shell-Shell Composites: SiOâ‚‚@PMDA-Si-Tb@SiOâ‚‚ and SiOâ‚‚@PMDA-Si-Tb-phen@SiOâ‚‚.

Two novel core-shell composites SiO₂@PMDA-Si-Tb, SiO₂@PMDA-Si-Tb-phen with SiO₂ as the core and terbium organic complex as the shell, were successfully synthesized. The terbium ion was coordinated with organic ligand forming terbium organic complex in the shell layer. The bi-functional organosilane ((HOOC)₂C₆H₂(CONH(CH₂)₃Si(OCH₂CH₃)₃)₂ (abbreviated as PMDA-Si) was used as the first ligand and phen as the second ligand.

Influence of citrate on phase transformation and photoluminescence properties in LaPO and LaPO:Eu.

The hexagonal and monoclinic phase LaPO and LaPO:Eu nanostructures have been controllably synthesized by a citrate-induced hydrothermal process at 100 °C. The crystal growth of LaPO nanostructures was investigated, and the phase transformation of nanostructured LaPO was systematically studied by varying the citrate concentration, pH value and reaction temperature. When 0.

Preparation, characterization and luminescence properties of core-shell ternary terbium composites SiO@Tb(MABA-Si)•L.

Two novel core-shell structure ternary terbium composites SiO@Tb(MABA-Si)·L(L:dipy/phen) nanometre luminescence materials were prepared by ternary terbium complexes Tb(MABA-Si)·L·(ClO)·2HO shell grafted onto the surface of SiO microspheres. And corresponding ternary terbium complexes were synthesized using (CONH(CH)Si(OCHCH)) (denoted as MABA-Si) as first ligand and L as second ligand coordinated with terbium perchlorate. The as-synthesized products were characterized by means of IR spectra, HNMR, element analysis, molar conductivity, SEM and TEM.

Toll-like receptor 4 signaling plays a role in triggering periodontal infection.

Toll-like receptors (TLRs) are a group of sensors on the surface of antigen-presenting cells, such as dendritic cells and macrophages, which recognize microbial pathogens and induce innate and adaptive immune responses. Periodontitis is an inflammatory disease characterized by the destruction of tooth-supporting structures. In order to address whether TLR4 signaling plays a role in periodontitis, we studied the gene expression change in human periodontal ligament cells (HPDLCs) in response to TLR4 ligand, lipopolysaccharide treatment by microarray analysis.

[Study of three-dimensional model on biomechanical characteristics of mandibular fractures in different site].

Objective: To determine the biomechanical characteristics of mandibular fractures in different site.

Methods: Nine adult mandibular specimens were measured precisely. The data was used to establish a three-dimensional model.

[Effect of yishenqinghuo recipe on periodontal inflammation and immunity of rats with experimental periodontitis].

Purpose: To evaluate the effect of Yishenqinghuo recipe on periodontal inflammation and immunity of rats with experimental periodontitis.

Methods: 12 months old Spague-Dawley rats were used in this study. 78 rats were randomly divided into 4 groups.

[Effects of aniline and phenol on freshwater algae growth].

By the methods of bioassay, this paper studied the effects of aniline or phenol on the growth of Chlorella pyrenoidosa and Scenedesmus obiquus. The results showed that these two compounds had evident effects on the growth of test algae species. For the same species, aniline was more toxic.