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By the methods of bioassay, this paper studied the effects of aniline or phenol on the growth of Chlorella pyrenoidosa and Scenedesmus obiquus. The results showed that these two compounds had evident effects on the growth of test algae species. For the same species, aniline was more toxic. Under the same concentration of the compounds, S. obiquus was more sensitive than C. pyrenoidosa. These two algae species could degrade or absorb parts of the compounds, and phenol in particular, when their concentrations were lower.
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Environ Int
August 2025
Eawag: Swiss Federal Institute of Aquatic Science and Technology, Ueberlandstrasse 133, 8600, Duebendorf, Switzerland; Institute of Biogeochemistry and Pollutant Dynamics, Universitaetstrasse 16, 8092, Zurich, Switzerland. Electronic address:
Synthetic antioxidants (SAOs) are widely used additives in industrial and consumer products, yet their human exposure and fate throughout wastewater treatment remain poorly understood. This study investigates the occurrence of SAOs and their human metabolites in wastewater influent as well as their abatement in three wastewater treatment plants (WWTPs) employing both conventional and advanced treatment technologies. In vitro human liver S9 assays were performed to generate a SAO metabolite MS2 library containing over 2500 potential metabolites, which was matched against wastewater influent data.
View Article and Find Full Text PDFClin Transl Sci
September 2025
Division of Allergy, Asthma and Clinical Immunology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, South Korea.
Nonsteroidal anti-inflammatory drug (NSAID) hypersensitivity reactions are commonly reported but often overestimated due to reliance on clinical history alone. Accurate diagnosis and identification of safe alternative medications are essential for appropriate management. This retrospective study aimed to evaluate the clinical manifestations of NSAID hypersensitivity, assess the diagnostic value and safety of aspirin oral provocation testing, and investigate the tolerability of alternative medications, including acetaminophen, meloxicam, and celecoxib.
View Article and Find Full Text PDFNutrients
August 2025
School of Basic Medical Science, Health Science Center, Ningbo University, Ningbo 315211, China.
: Obesity is clinically known to be associated with an increased risk and aggravated pathology of Alzheimer's disease (AD). A high-fat diet (HFD), the major contributor to obesity, induces neuroinflammation and central insulin resistance, both of which are linked to synaptic dysfunction. Our previous studies demonstrated that avenanthramide-C (Avn-C), a natural oat-derived phenolic compound, exerts anti-inflammatory effects and alleviates synaptic dysfunction in conventional AD models.
View Article and Find Full Text PDFAnal Bioanal Chem
August 2025
Department of Chemistry, Faculty of Science, Dicle University, Diyarbakir, 21000, Turkey.
Mixed-mode chromatography is increasingly valued for retaining analytes with diverse polarity and charge by integrating hydrophilic interaction (HILIC), reversed-phase (RPLC), and ion-exchange mechanisms. However, designing stationary phases that are both easy to synthesize and chromatographically versatile remains challenging. This study presents DEA-Mix-SP, a novel silica-based stationary phase functionalized with diethanolamine via [2-(3,4-epoxycyclohexyl)ethyl]trimethoxysilane, offering a simple synthetic route for broad-spectrum separation.
View Article and Find Full Text PDFBiosensors (Basel)
August 2025
Laboratory of Process Engineering and Environment, Faculty of Sciences and Techniques, Hassan II University of Casablanca, P.A. 146, Mohammedia 28806, Morocco.
The demand for rapid, energy-efficient, and low-toxicity methods for synthesizing molecularly imprinted polymers (MIPs) is increasing, particularly for applications in environmental monitoring and green chemistry. In this context, the present work focuses on the development of a novel laser-assisted method for MIP synthesis, employing a visible laser (450 nm) and erythrosine B as a green photoinitiator. This visible-light approach enables fast and spatially controlled polymerization while avoiding the drawbacks of conventional methods (thermal heating, UV synthesis), such as the use of toxic initiators like AIBN and the need for UV shielding.
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