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Article Abstract

SiO@GdPO:Tb@SiO nanoparticles with core-shell-shell structure were successfully synthesized by a cheap silane coupling agent grafting method at room temperature. This method not only homogeneously coated rare-earth phosphate nanoparticles on the surface of silica spheres but also saved the use of rare-earth resources. The obtained nanoparticles consisted of SiO core with a diameter of approximately 210 nm, GdPO:Tb intermediate shell with thickness of approximately 7 nm, and SiO outer shell with thickness of approximately 20 nm. This unique core-shell-shell structured nanoparticles exhibited strong luminescence properties compared with GdPO:Tb nanoparticles. The core-shell-shell structured nanoparticles can effectively quench the intrinsic fluorescence of bovine serum albumin through a static quenching mode. The as-synthesized nanoparticles show great potential in biological cell imaging and cancer treatment.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277279PMC
http://dx.doi.org/10.1098/rsos.192235DOI Listing

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