The Relationship Between Religious Attachment and Spiritual Care Competencies in Nursing Students: a Cross-Sectional Study in Turkey.

In this study, it was aimed to determine the effect of religious attachment in nursing students on their spiritual care competence levels. This cross-sectional study was conducted with Turkish nursing students in 2022 (n = 348). The sociodemographic information form, spiritual health scale-short form (SHS-SF), and spiritual care competence scale (SCCS-T) were used for data collection.

Psychiatrists' mental health and coping strategies: Does the shoemaker's son always go barefoot?

Objectives: It would be prudent to consider the mental health of psychiatrists, who are entrusted with the responsibility of caring for our mental well-being. This study aimed to examine psychiatrists' mental health and coping strategies.

Methods: The study was conducted among 217 psychiatry residents and specialists in Turkey.

Artificial intelligence meets HIV education: Comparing three large language models on accuracy, readability, and reliability.

BackgroundThis study compares three large language models (LLMs) in answering common HIV questions, given ongoing concerns about their accuracy and reliability in patient education.MethodsModels answered 63 HIV questions. Accuracy (5-point Likert), readability (Flesch-Kincaid, Gunning Fog, Coleman-Liau), and reliability (DISCERN, EQIP) were assessed.

Comparison of the efficacy of mFOLFOX-6 and mDCF regimens in the treatment of metastatic gastric cancer: a multicenter retrospective study.

Background: Metastatic gastric cancer (GC) and gastroesophageal junction (GEJ) cancer are associated with a poor prognosis. Recent advancements in treatment have incorporated trastuzumab, anti-PD-1 agents, and anti-claudin therapies alongside chemotherapy (ChT), significantly improving outcomes. Contemporary studies predominantly employ doublet ChT as the backbone for these regimens, although historically triplet ChT regimens have been favored, particularly in younger patients requiring rapid tumor shrinkage.

Synthesis, Characterization, and Comprehensive In Vitro and In Silico Evaluation of the Anti-Inflammatory Potential of Novel 1,2,3-Triazole-Arylidenehydrazide/Thiazolidinone Hybrids.

Five novel 1,2,3-triazole/arylidenehydrazide/thiazolidinone hybrid compounds (7-11) were synthesized and characterized using NMR, HRMS, IR, and HPLC purity analysis. The cytotoxicity of these compounds was evaluated on fibroblasts and THP-1 cells, showing that all compounds were nontoxic at the tested concentrations. The wound healing assay revealed that compounds 7, 9, and 10 significantly enhanced wound closure, with a 7.

Four-week remotely supervised aerobic exercise during the COVID-19 era: Exploring physical performance and psychosocial health in adults without COVID-19 living in rural settings.

Rationale: Aggressive osteoblastoma (AO) is an extremely rare cancer that mainly affects the spine and long bones and is less frequent in craniofacial bones. Cases involving the skull are even rarer, and the low incidence rates limit our understanding of the distribution and treatment strategies of AO. The aim of this study was to explore the clinical features, imaging findings, pathological characteristics, diagnoses, treatment, and prognosis of AO involving the skull.

Perceived social support and self-compassion as serial mediators of relationship between childhood maltreatment and psychological distress.

Background: Previous studies have consistently found a robust relationship between childhood maltreatment and psychological distress. Despite the increasing number of studies in recent years that have identified social support or self-compassion as potential mechanisms in this relationship, no study examines the mediating role of both social support and self-compassion in adults.

Aim: This study aimed to investigate social support and self-compassion as potential mediators in the relationship between childhood maltreatment and psychological distress using a serial mediation model.

Temporal Variation of Biochemical Markers and Adenoma Predictors in Normocalcemic Primary Hyperparathyroidism: A Multicenter Retrospective Analysis.

Objective: This study aimed to evaluate the diagnostic performance of biochemical markers in normocalcemic primary hyperparathyroidism (nPHPT), analyse their temporal variations, and assess their correlation with adenoma localisation and size.

Methods: In this multicenter retrospective study-the largest patient cohort reported in the literature to date (n = 474) we comprehensively profiled normocalcemic patients diagnosed with primary hyperparathyroidism nPHPT was diagnosed based on persistently elevated PTH levels with normal serum calcium after excluding secondary causes such as vitamin D deficiency, renal impairment, and other conditions. This retrospective multicenter study included a large cohort of patients whose biochemical markers-including serum calcium, phosphorus, magnesium, vitamin D, parathyroid hormone (PTH), and glomerular filtration rate (GFR)-were measured at three time points, using standardised laboratory protocols.

Evaluating the impact of altitudinal variations on COVID-19 mortality rates: a comprehensive analysis.

Background: High altitude, known for its effects on respiratory diseases, was analyzed for its potential protective role. Data from the New York Times COVID-19 repository, U.S.

Anomalous D₀ → F₄ transition induced by alkali ion co-doping in Eu-activated K₇SrY₂(BO) borates: A Judd-Ofelt and photoluminescence analysis for pc-WLEDs.

In this study, red-emitting K₇SrY₂(BO):Eu phosphors were synthesized via high-temperature solid-state reaction. The effects of Li and Na co-doping on structural and photoluminescent properties were investigated. XRD and Rietveld refinement confirmed a phase-pure trigonal structure.

Ultrasonographic and CBCT analysis of foreign bodies and dental materials.

Background: To reveal the radiodensity and sonographic characteristics of various foreign bodies and dental materials to aid in the diagnosis of these materials.

Methods: The study included 41 objects consisting of various foreign bodies and dental materials. The objects were examined by embedding them in bovine gelatin, an in vitro environment and their radiodensity was evaluated using cone-beam computed tomography (CBCT).

Management and Outcomes of Urinary Tract Involvement in Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy (CRS/HIPEC): A Retrospective Cohort Study.

: The combined use of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is employed for the treatment of peritoneal carcinomatosis (PC). To achieve optimal cytoreduction, there may be a need for extensive resection and subsequent reconstruction of urologic structures. This study was designed to evaluate the outcomes of urinary tract resection or repair performed in CRS/HIPEC in terms of operative and oncological outcomes.

Disruption of consciousness depends on insight in obsessive-compulsive disorder and on positive symptoms in schizophrenia.

Disruption of conscious access contributes to the advent of psychotic symptoms in schizophrenia and could also explain lack of insight in other psychiatric disorders. In this study, we explored how insight and psychotic symptoms related to disruption of consciousness in obsessive-compulsive disorder (OCD) and schizophrenia, respectively. Patients with schizophrenia, and patients with OCD with good versus poor insight and matched controls underwent clinical assessments and performed a visual masking task.

Breast Cancer Awareness Scale: Turkish Validity and Reliability Study Among Adult Women.

Aim: This study aimed to assess the validity and reliability of the Turkish version of the Breast Cancer Awareness Scale (BCAS-TR) for assessing breast cancer awareness among Turkish women.

Methods: The data of this methodological study were collected by face-to-face interview technique from 352 women over 18 years of age at a family health centre in Ankara, Türkiye. The BCAS-TR, adapted from the original 35-item scale, assessed knowledge, attitudes and behaviours related to breast cancer.

The effects of particle size, morphology and performance of antibacterial nanocomposites on sustainable lyocell fabrics coated by the combined pad-dry-cure and sol-gel methods.

The demand for safe, comfortable and sustainable materials in antibacterial textile production has led to the research of the new alternative materials and methods. This study focuses on the use of lyocell that is one of the promising regenerated cellulosic fiber as an alternative material and the application of the silver and zinc oxide nanoparticles by the combined pad-dry-cure and sol-gel methods to obtain durable performance. In addition, the dependence of the antibacterial properties of the coatings on the particle size and morphology of the nanocomposites and the performance of zinc oxide nanoparticles in the nanocomposite form with silver nanoparticles on lyocell fabrics have been comparatively and comprehensively investigated.

Enhanced OH Transport Properties of Bio-Based Anion-Exchange Membranes for Different Applications.

The demand for anion exchange membranes (AEMs) is growing due to their applications in water electrolysis, CO reduction conversion and fuel cells, as well as water treatment, driven by the increasing energy demand and the need for a sustainable future. However, current AEMs still face challenges, such as insufficient permeability and stability in strongly acidic or alkaline media, which limit their durability and the sustainability of membrane fabrication. In this study, polyvinyl alcohol (PVA) and chitosan (CS) biopolymers are selected for membrane preparation.

Targeted Therapy for Glioblastoma: Synergistic Effects of GO/C-TMZ,@, PmAb and Magnetic Hyperthermia.

This study investigates the therapeutic potential of a nanohybrid structure, GO/C-TMZ@PmAb MNP, for targeted glioblastoma treatment by integrating chemotherapy with magnetic hyperthermia. Characterization of the nanohybrid confirmed successful conjugation of Panitumumab (PmAb) and effective loading of Temozolomide (TMZ), ensuring targeted delivery to glioblastoma cells. In vitro experiments demonstrated enhanced cytotoxicity and a significant increase in late-stage apoptosis in U-87 MG and U-251 MG glioblastoma cell lines, particularly when combined with an alternating magnetic field (AMF), highlighting the synergistic effect of combined therapy.

A rare manifestation of Henoch-Schoenlein purpura: haemoptysis secondary to pulmonary involvement - a case report.

Henoch-Schoenlein purpura (HSP) in children is the most prevalent form of vasculitis. While the lungs are recognised as potential target organs in several vasculitides during childhood, pulmonary involvement in HSP is exceptionally rare. A 5-year-old girl presented with haemoptysis during week 3 of HSP vasculitis.

When smartphones take over: a mixed methods study of phubbing in child and adolescent psychiatry.

Introduction: The recent term phubbing is the amalgamation of the words phone and snubbing, and refers to those phone-related behaviors through which we ignore, dismiss, or otherwise eschew social interactions. Little is known about phubbing among child and adolescent psychiatrists (CAPs), a group often called upon to provide direction on how to guide children in their rapidly evolving cybernetic contexts.

Methods: We conducted a mixed methods study of trainees in CAP (n = 73; 68% women), recruited in the US (6 training programs; n = 35) and Türkiye (5 programs; n = 38).

Novel thiazolidinedione hybrids as cholinesterase inhibitors and targeting neuroblastoma: design, synthesis, in vitro and in silico biological evaluations.

In this study, a novel series of eleven 3,5-disubstituted thiazolidine-2,4-dione (TZD) derivatives were rationally designed and synthesized, incorporating tertiary amine moieties to enhance cholinesterase binding. The acetamide-linked TZD scaffold was selected for its potential dual functionality: cholinesterase inhibition and cytotoxicity against neuronal cells. All compounds were evaluated for their inhibitory activities against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), alongside cytotoxicity assays on SH-SY5Y cancerous neuroblastoma and HEK-293 healthy cells.

The Role of Lurasidone in Early-Onset Schizophrenia and Obsessive-Compulsive Disorder: A Case Report.

The comorbidity of schizophrenia and obsessive-compulsive disorder (OCD) has been demonstrated to result in more severe symptoms and a worse prognosis for patients, as well as a more challenging treatment process for clinicians. Lurasidone is a second-generation atypical antipsychotic approved for the treatment of schizophrenia. This case report aims to share the use and treatment process of lurasidone in a 28-year-old male patient with a history of OCD and schizophrenia since childhood.

Comprehensive immunohistochemical analysis associated with the tumor microenvironment including monocarboxylate transporters in pancreatic ductal adenocarcinoma.

Background/aims: Pancreatic ductal adenocarcinoma is an aggressive neoplasm with poor prognosis. The metabolic properties of its desmoplastic stroma are hypothesized to contribute to disease progression. Aberrant metabolism in tumor cells and desmoplastic stroma results in the accumulation of metabolic by-products, with lactate being the most important, released into the extracellular space by monocarboxylate transporters (MCTs).

Emergency radiology in displaced populations: imaging and practical challenges.

Migrants and refugees tend to use emergency departments as their primary source of care, leading to a substantial increase in emergency radiological imaging. Migrants and refugees have risk factors, such as low vaccination rates, poor hygiene, malnutrition, and inadequate self-care, which increase their risk of contracting infectious diseases. For example, the prevalence of tuberculosis among refugee populations in host countries is increasing, and imaging findings related to tuberculosis are frequently observed by radiologists.