The effect of sleep-oriented non-pharmacological interventions in preventing delirium: a systematic review of randomized controlled trials.

Aim: To systematically review randomized controlled trials evaluating the efficacy of sleep-oriented non-pharmacological interventions for delirium prevention in intensive care units.

Methods: We searched PubMed, Web of Science, Scopus, and the Cochrane Library for randomized controlled trials evaluating the efficacy of sleep-oriented, non-pharmacological interventions for delirium prevention in intensive care units published in English between 2019 and 2024. The methodological quality of the included studies was independently evaluated by two researchers using the Joanna Briggs Institute tool.

Risk Factors Associated With Swallowing Complaints and Oral Sensory Problems in Children With a History of Preterm Birth.

Aim: Although previous studies have investigated feeding difficulties in preterm children, research exploring contextual risk factors within low- and middle-income countries like Turkey remains limited. This prospective cross-sectional study aims to identify factors associated with swallowing difficulties and oral sensory problems in children aged 3-10 years who were born preterm.

Method: A total of 158 parents of preterm children aged 3-10 years completed the Pediatric Eating Assessment Tool (PEDI-EAT-10) and the Oral Sensory Profile (Oral-SP).

RuBisCO-based protein and film from Rumex patience L.: Effects of green extraction and NADES plasticization on structural and functional properties.

Growing interest in sustainable food packaging has driven the development of bio-based films from underutilized plant proteins. Rumex patientia L. (edible dock), a perennial leafy plant rich in RuBisCO, represents a promising yet largely untapped source of functional film-forming proteins.

Experience of pregnant women living in temporary shelters post-earthquake: a phenomenological study.

Background: Continuing health services after disasters and ensuring that pregnant women receive antenatal care are important to protect the health of mothers and babies.This study aims to investigates the experiences of pregnant women living in temporary shelters cities post-earthquake.

Method: A qualitative approach was employed to explore pregnant women experiences during the earthquake, that hit the Pazarcık district of central Kahramanmaraş, Turkey, on February 6, 2023.

Key considerations and recommendations for recruiting older adults in physical activity studies.

Background: Despite substantial evidence supporting the benefits of physical activity (PA) for older adults, participation rates remain low due to physical, psychological, social, and institutional barriers. Recruiting older adults for PA studies thus presents significant challenges, particularly for socially vulnerable populations and those facing digital literacy limitations in technology-assisted PA interventions. The present study aimed to articulate and establish a consensus among multidisciplinary and multinational PA experts regarding key considerations and requirements for designing and implementing recruitment of older adults for PA studies.

Targeted Therapy for Glioblastoma: Synergistic Effects of GO/C-TMZ,@, PmAb and Magnetic Hyperthermia.

This study investigates the therapeutic potential of a nanohybrid structure, GO/C-TMZ@PmAb MNP, for targeted glioblastoma treatment by integrating chemotherapy with magnetic hyperthermia. Characterization of the nanohybrid confirmed successful conjugation of Panitumumab (PmAb) and effective loading of Temozolomide (TMZ), ensuring targeted delivery to glioblastoma cells. In vitro experiments demonstrated enhanced cytotoxicity and a significant increase in late-stage apoptosis in U-87 MG and U-251 MG glioblastoma cell lines, particularly when combined with an alternating magnetic field (AMF), highlighting the synergistic effect of combined therapy.

Reliability of Static and Dynamic Balance Tests and Their Interrelationships in Children With Cochlear Implants.

Background: Children with cochlear implants are at increased risk of vestibular dysfunction and balance impairments, yet the reliability of commonly used static and dynamic balance assessments has not been thoroughly evaluated in this population. This study aimed to assess the reliability of static balance tests (single-leg stance test [SLST] and tandem Romberg test [RT], performed with eyes open [EO] and eyes closed [EC]), dynamic balance tests (timed up and go test [TUG] and figure-of-eight walk test [F8WT]) and Paediatric Balance Scale (PBS), which includes both static and dynamic components, and to examine relationships among these tests in children with cochlear implants.

Methods: Sixty-two children with cochlear implants, aged 7-13 years, performed all the balance tests.

Skin in the game: a review of computational models of the skin.

With the vast advances in computing technology, computational (or in silico) modelling has emerged as a transformative tool in dermatology. These findings can provide novel insights into complex biological processes and aid in the development of innovative therapeutic and regenerative strategies for the skin. Modelling combines experimental data and knowledge across multiple disciplines, serving as a common framework to elucidate the workings of the skin.

Biomechanical determinants of high ball speed during instep soccer kick by prepubescent male athletes: the importance of muscle elasticity.

Background: The purpose of this study was to determine whether muscle viscoelastic properties, muscle activation and thigh rotational velocity and rotational acceleration are significantly associated with high ball speed during instep soccer kick by prepubescent male athletes.

Methodology: This study included 31 prepubescent male soccer players. Maximal ball speed during the instep kick was measured using a radar gun.

Strong polymer-cellulose interfacial engineering enables hydrogel-enhanced separators with multiscale networks for zinc-ion batteries.

Cellulose paper-based separators have attracted significant attention as promising materials for aqueous zinc ion batteries (ZIBs) owing to their excellent wettability, chemical stability, and environmental compatibility. However, water molecules penetrate into the amorphous regions of cellulose to induce plasticization, thus increasing the mobility of molecular chains and disrupting the intermolecular hydrogen bonding within cellulose. This degradation mechanism severely deteriorates battery cycling performance and capacity retention, thereby hindering the utility of cellulose paper-based separators in aqueous ZIBs.

Food Safety and Waste Management in TV Cooking Shows: A Comparative Study of Turkey and the UK.

This study examines food safety and waste behaviours depicted in the televised cooking competition , a globally franchised series that showcases diverse culinary traditions and influences viewers' practices. The research focuses on the editions aired in Turkey and the United Kingdom, two countries with distinctly different social and cultural contexts. Video content analysis, based on predefined criteria, was employed to assess observable behaviours related to food safety and waste.

Fucoidan-functionalized molybdenum carbide nanospheres for combined therapy: Photothermal, photodynamic, and chemotherapeutic effects on triple-negative breast cancer cell lines.

This study evaluates the therapeutic potential of fucoidan-functionalized molybdenum carbide (Mo₂C@C@Fuc) nanospheres and their combination with paclitaxel (PTX) for targeted cancer therapy, with a focus on triple-negative breast cancer (TNBC) cell lines. The nanospheres exhibited 85-90 % drug-loading efficiency and pH-responsive release, ensuring enhanced delivery in acidic tumor microenvironments. Reactive oxygen species (ROS) assays revealed significant ROS generation under near-infrared (NIR) irradiation, particularly in the PTX/Mo₂C@C@Fuc group, selectively inducing oxidative stress in TNBC cells (4T1 and MDA-MB-231) while sparing healthy fibroblasts (L929).

Evaluation of the type D personality and its association with cardiovascular risk and disease-related parameters in patients with systemic sclerosis.

Objective: The objective of the study was to assess the type D personality, social inhibition, and negative affectivity and their association with cardiovascular risk and disease-related parameters in patients with systemic sclerosis.

Materials And Methods: This cross-sectional study included patients with systemic sclerosis (n = 84) and controls (n = 74). We recorded the sociodemographic parameters, blood pressure (mmHg), and laboratory parameters (mg/dL) of the study groups, as well as disease-related parameters in patients with systemic sclerosis, along with the modified Rodnan skin score.

The effect of mechanical massage on labor pain, duration and maternal satisfaction: a randomized controlled trial.

Background: There are limited studies on the use of mechanical massage applications during labor, but its use is expected to increase with the changing technologies. This study was conducted to determine the effects of mechanical massage (controlled by the user) applied on pain during labor, labor duration, and maternal satisfaction.

Methods: One hundred and fifty-four primiparous pregnant women were included in the study.

Xanthan gum-based formulations for additive manufacturing: Scientific developments in drug delivery and biomedical applications.

The potential of three-dimensional (3D) printing as an approach for developing advanced, patient-specific, highly accurate, and customizable materials has captured the interest of the pharmaceutical and biomedical sciences sectors. The rheological and biodegradation characteristics of xanthan gum in 3D printed formulations make them an excellent platform technology for drug administration and biological applications, according to research. Applications for 3D printing platforms include transdermal, implantable, ophthalmic, and drug delivery.

Mobilization with movement plus exercise versus exercise alone for patients with central sensitization associated with chronic subacromial pain syndrome: a sham-controlled randomized clinical trial.

Background: The efficacy of mobilization with movement (MWM) in addressing central sensitization and widespread mechanical hyperalgesia in patients with subacromial pain syndrome (SPS) remains unclear. This study aimed to evaluate the efficacy of MWM combined with exercise in improving the Central Sensitization Inventory (CSI) score, widespread mechanical hyperalgesia, and functional disability in patients with central sensitization associated with SPS.

Methods: This study was designed as a single-blind, randomized, sham-controlled trial.

Application of tannic acid and Fe crosslinking-enhanced chitosan films for wax apple (Syzygium samarangense) preservation.

This study examines the effects of edible chitosan coatings reinforced with tannic acid (TA) and ferric iron (Fe) double crosslinking on the quality of wax apples stored at room temperature. The effects of chitosan (CS) and CS/TA/Fe coatings on wax apple weight loss, decay index, respiration rate, titratable acidity, total phenolics, and other quality parameters were investigated. The weight loss and decay index of wax apples increased over time, with the CS coating delaying both compared to untreated fruits.

Innovative oleogels: Developing sustainable bioactive delivery systems for healthier foods production.

Oleogels have emerged as an excellent medium for delivering bioactive compounds. This study highlights and discusses recent advances in developing, producing, characterizing, and applying oleogels for delivering functional and bioactive compounds in food products. The review revealed that oleogels present a promising opportunity to create healthier food products by enhancing their functional and nutritional profiles.

Ultrasound Evaluatıon of Muscle Movement During Swallowing Maneuvers: Trials on 3 Maneuvers.

Ultrasound (US), a technology extensively utilized and deemed safe for medical purposes, represents an innovative approach that has recently been applied in the evaluation of swallowing functions as well as in the rehabilitation processes. Therapeutic interventions often prioritize swallowing maneuvers as preferred options. Nevertheless, the current body of literature indicates that the application of ultrasound in the assessment and treatment of swallowing disorders remains limited, with a scarcity of studies investigating muscle activation and laryngeal elevation during these swallowing maneuvers.

Optimization of Ethanol Extraction Conditions From Sun-Dried Apricot and Prediction of Antioxidant, Phenolic, and Flavonoid Contents and Their Effects on HCT116 Cells Using Artificial Neural Networks.

This study aimed to optimize the ethanol extraction conditions of sun-dried apricot ( L.) and evaluate the antioxidant capacity, phenolic, and flavonoid contents of the obtained extracts. Response surface methodology (RSM) was applied to determine the optimal extraction conditions, which were identified as 60°C temperature, 34% ultrasonic power, 46 min sonication time, and a 4 g/mL solid-liquid ratio.

The relationship between care dependency and self-efficacy in older adult patients with chronic obstructive pulmonary disease.

Background: Chronic obstructive pulmonary disease is a chronic, progressive and irreversible disease and is an important health problem with significant effects on the life status of older adult patients. However, the effect of care dependency on self-efficacy in older adult patients with chronic obstructive pulmonary disease has not been sufficiently investigated in the literature.

Objectives: The purpose of this study was to investigate the association between care dependency and self-efficacy among older adults with chronic obstructive pulmonary disease.

Exploring plant-based approaches: A review of protein extraction, characterization, food and pharmacological application from fruit pulps.

Protein is an essential macronutrient for human growth and survival. As global demand rises, sustainable and unconventional protein sources with high nutritional and functional potential must be explored, though many remain underutilized and overlooked. Among them, fruit pulp proteins offer a promising and sustainable alternative with unique bioactive properties and diverse applications in the food industry.

Reconstructed Wood Carbon Aerogel with Single-Atom Sites for Flexible Zn-Air Batteries.

Single-atom catalysts (SACs) have become vital air cathodes for metal-air batteries, but fabricating monolithic SACs with high catalytic activity and mechanical strength is currently lacking. Herein, an all-natural wood carbon aerogel with single-atom sites is reconstructed via modulating the multi-interactions within lignocellulosic components. Cellulose nanofiber (CNF) constitutes an oriented scaffold via physical interweaving and strong electrostatic repulsion, while lignosulfonate, acting as a multifunctional bioligand, coordinates with metal ions and forms hydrogen bonds with CNF to prevent the agglomeration of adjacent metal atoms.

Impregnation of Melaleuca Family Essential Oil Nanoemulsions into Pectin:Polyvinyl Alcohol Patches to Provide an Antibacterial Environment for Infected Wounds.

Essential oils have long been utilized in food, cosmetic, and medicinal applications. Recently, their biomedical use for wound healing, skin repair, and tissue regeneration has gained considerable attention. In this study, tea tree oil (TTO) and niaouli oil (NIO) were formulated into aqueous nanoemulsions (NEs) and incorporated into pectin/polyvinyl alcohol (PP) thin films to develop antibacterial wound dressing patches.

Exploring the Properties of Carboxymethyl Cellulose Blended With Other Polymeric Compounds for the Formulation of Biodegradable Packaging Films and Edible Coatings: A Review.

Carboxymethyl cellulose (CMC) is a leading hydrocolloid for biodegradable packaging films and edible coatings due to its film-forming ability, biodegradability, and nontoxicity. However, its application is limited by moisture sensitivity, poor mechanical strength, flammability, and inadequate gas barrier properties. This review explores the formulation, structural properties, and practical applications of CMC when blended with other polymeric compounds such as cellulose, starch, alginate, chitosan, and polylactic acid to overcome these limitations.