Comparative analysis of complete chloroplast genomes of and , two commonly used medicinal plants in southern China.

and , belonging to the genus , are ethnomedicinal plants that contain valuable medicinal and nutritional compounds. However, their medicinal materials are frequently confused in the Chinese medicinal materials market. Moreover, molecular genomic resources for this genus remain limited, which hinders phylogenetic studies.

Comparative Transcriptome and Metabolome Analyses Provide New Insights into the Molecular Mechanisms Underlying Taproot Development and Bioactive Compound Biosynthesis in vahl.

Background: vahl is a famous Chinese medicinal plant. The root is the main organ accumulating bioactive compounds, and its development is directly related to the yield and quality of the harvested However, the molecular mechanisms underlying the bioactive compound biosynthesis occurring during the root development of are unknown.

Method: Transcriptome and widely targeted metabolome analyses were performed to investigate gene expression and metabolite variation during the development of taproots.

Physiological, biochemical, and transcriptomic analyses reveal potential candidate genes of Platostoma palustre in response to salt stress.

Background: Salt stress poses a genuine threat to plants, impeding their growth, development, and yields. Platostoma palustre (Blume) A.J.

Genes involved in the regulation of alkaloid and flavonoid biosynthesis in different tissues of Sophora tonkinensis via transcriptomics and metabolomics.

Background: Sophora tonkinensis Gagnep is a significant Chinese herbal medicine, primarily composed of alkaloids and flavonoids, which are its key pharmacological components. Despite its importance, the metabolic pathways of these substances in S. tonkinensis remain inadequately explored.

Chemical and Mechanistic Prediction Analysis of Anti-obesity Properties of Guang Hawthorn (Malus doumeri) Leaves using Network Analysis.

Objective: This study aimed to characterize the bioactive compounds in Guang hawthorn (Malus doumeri) leaf extracts and evaluate their potential anti-obesity effects.

Methods: 70% Ethanol and ethyl acetate extracts from M. doumeri leaves were administered to high-fat diet-induced obese rats.

The Light-Regulated Transcription Factor Promotes Flavonoids in .

Dunn is rich in flavonoids, which were previously demonstrated to respond to changing light conditions. In this study, through weighted gene co-expression network analysis (WGCNA), genes were screened as the potential regulator for these light-intensity-induced changes. One gene, , was chosen for in-depth research.

Identification of key modules and genes in response to high-temperature stress in Platostoma palustre based on WGCNA.

Platostoma palustre (Blume) A. J. Paton is one of the important medicinal and edible plants in China, and it is widely cultivated in tropical and subtropical regions of southern China.

Genome-wide analysis of the bHLH gene family in Spatholobus suberectus identifies SsbHLH112 as a regulator of flavonoid biosynthesis.

Spatholobus suberectus Dunn (S. suberectus), a medicinal herb from the Leguminosae family, is widely utilized in traditional medicine. The dried stem of S.

Comprehensive analysis of the NAC transcription factor gene family in Sophora tonkinensis Gagnep.

Background: Sophora tonkinensis Gagnep. has long been utilized in the treatment of anti-inflammatory and pain-relieving, with its principal active compounds being alkaloids and flavonoids. NAC transcription factors, a large family of plant-specific regulators, play pivotal roles in growth, development, stress responses, and secondary metabolism.

Metabolomics Analysis of the Mechanism of Yuquan Capsules in the Treatment of T2DM Rats Using UPLC/MS.

Purpose: Yuquan capsule (YQC) is a well-known proprietary Chinese medicine used for the treatment of type 2 diabetes mellitus. The aim of this study was to investigate the potential mechanism and efficacy of YQC in the treatment of T2DM by means of metabolomics.

Methods: Thirty-two male SD rats were randomly divided into four groups of control, type 2 diabetic mellitus (T2DM), metformin (Met), and YQC.

Genome-wide identification and expression analysis of the WRKY gene family reveal essential roles in abiotic stress responses and polysaccharides and flavonoids biosynthesis in Platostoma palustre (Blume) A. J. Paton.

Background: Platostoma palustre (Blume) A. J. Paton is an economic crop with medicinal and edible properties.

Analysis of the Spatholobus suberectus full-length transcriptome identified an R2R3-MYB transcription factor-encoding gene SsMYB158 that regulates flavonoid biosynthesis.

Spatholobus suberectus Dunn (Leguminosae) has been used for medicinal purposes for a long period. Flavonoids are the major bioactive components of S. suberectus.

Widely targeted metabolomics reveals the phytoconstituent changes in leaves and stems at different growth stages.

is an important edible and medicinal plant. To gain a comprehensive and clear understanding of the variation patterns of metabolites in , we employed the UPLC-MS platform along with widely targeted metabolomics techniques to analyze the metabolites in the stems and leaves of at different stages. Our results revealed a total of 1228 detected metabolites, including 241 phenolic acids, 203 flavonoids, 152 lipids, 128 terpenes, 106 amino acids, 79 organic acids, 74 saccharides, 66 alkaloids, 44 lignans, etc.

3α-Hydroxybufadienolides in Bufo gallbladders: structural insights and biotransformation.

Bufadienolides, naturally occurring steroids primarily found in toads, have garnered attention for their pharmacological properties and ecological significance. In this study, we isolated and identified 21 bufadienolides from the gallbladders of Bufo gargarizans, comprising four new compounds and 17 known ones. Notably, the predominance of 15 bufadienolides with a 3α-OH configuration in toad bile differs significantly from the 3β-OH bufadienolides found in venom secreted by toad glands.

Effects of different colors of plastic-film mulching on soil temperature, yield, and metabolites in Platostoma palustre.

Platostoma palustre is an annual herb and an important medicinal and edible plant in southern China. Plastic-film mulching is an effective agronomic practice in the cultivation system of P. palustre, of which black-film mulching is the most common.

A Comprehensive Review of the Pharmacology, Chemistry, Traditional Uses and Quality Control of Star Anise ( Hook. F.): An Aromatic Medicinal Plant.

Hook. F., also known as star anise, is one of the most important plants of the genus Anise in the family Magnoliaceae.

Transcriptomics and metabolomics association analysis revealed the responses of to cadmium.

an important medicinal herb, can absorb high amounts of cadmium (Cd) which can lead to excessive Cd contamination during the production of medicines and tea. Hence, it is crucial to investigate the response mechanism of under Cd stress to develop varieties with low Cd accumulation and high tolerance. Physiological response analysis, transcriptomics and metabolomics were performed on seedlings exposed to Cd stress.