MXene/PANI/SnO electrochemical sensor for the determination of 4-aminophenol.

An electrochemical sensor based on MXene/PANI/SnO nanomaterials was developed for the detection of 4-aminophenol (4-AP). In situ oxidative growth of PANI on the MXene surface effectively hindered the stacking of the lamellae and increased the specific surface area of the composites. Further complexation of tin dioxide with swelling properties of the structure provided adsorption and catalytic sites for 4-AP.

Jahn-Teller Distortion Enables Enhanced Piezoelectric Energy Harvesting Properties of a Metal-Pyrazolylborate Complex.

Molecular piezoelectrics have garnered significant attention in energy harvesting and sensing fields due to their high intrinsic piezoelectricity, low elastic properties, and excellent solution processability. Recent efforts have primarily focused on rationally tuning the piezoelectric performance of these materials through the molecular predesign of organic components. However, the regulation of piezoelectric properties via the central metal ion has remained relatively underexplored.

DNA Nanocage-Based Artificial Receptor Generator for Hydrophobic Interaction-Based Specific Membrane Anchoring.

Membrane receptor recognition is a specific biotargeting strategy for disease diagnosis and treatment, but it suffers from insufficient receptor expression levels. Hydrophobic interaction-based membrane anchoring strategy allows high anchoring density, but it lacks specificity. In this study, we present a DNA nanocage-based artificial receptor generator (DNARG) that combines the advantages of high specificity of receptor recognition and high density of hydrophobic membrane anchoring.

Contrastive Study on Substitution of the Bulky Phosphanide [P(SiPr)] toward Heavier Tetrylenes.

The super bulky sodium phosphanide, NaP(SiPr), was reacted with amidinatotetrylenes LECl (L = PhC(NBu), E = Si, Ge), resulting in the formation of phosphasilene LSi(SiPr) = PSiPr () and phosphanido germylene LGeP(SiPr) (), respectively. Investigation on the reactivity of and toward elemental sulfur was carried out, where a stepwise reaction yielding the silanethione LSi(=S)SiPr () and the silicon thioester analogue LSi(=S)SSiPr () was observed in the case of , while the treatment of with sulfur exclusively afforded the germanium thioester analogue. In addition, the reactions of with Fe(CO) and GeCl·1,4-dioxane led to the germylene-coordinated iron carbonyl and the asymmetric Ge-Ge-bonded complex, respectively, exhibiting the reactivity of the lone pair as well as a weak Ge-P bond.

Diverse Perovskite Solar Cells: Progress, Challenges, and Perspectives.

Perovskite materials have revolutionized optoelectronics by virtue of their tunable bandgaps, exceptional optoelectronic properties, and structural flexibility. Notably, the state-of-the-art performance of perovskite solar cells has reached 27%, making perovskite materials a promising candidate for next-generation photovoltaic technology. Although numerous reviews regarding perovskite materials have been published, the existing reviews generally focus on individual material systems (e.

Machine Learning-Enhanced Design of 2D TM(HXBHYB)@MOF-Based Single-Atom Catalysts for Efficient Oxygen Electrocatalysis.

This study integrates machine learning (ML) and density functional theory (DFT) to systematically investigate the oxygen electrocatalytic activity of two-dimensional (2D) TM(HXBHYB) (HX/YB = HIB (hexaaminobenzene), HHB (hexahydroxybenzene), HTB (hexathiolbenzene), and HSB (hexaselenolbenzene)) metal-organic frameworks (MOFs). By coupling transition metals (TM) with the above ligands, stable 2D TM(HXBHYB)@MOF systems were constructed. The Random Forest Regression (RFR) model outperformed the others, revealing the intrinsic relationship between the physicochemical properties of 2D TM(HXBHYB)@MOF and their ORR/OER overpotentials.

Slide-Ring Based Hydrogel Sensors with Extreme Wide Temperature Adaptability Toward Winter Swimming Sensing Application.

Conductive hydrogels have significant application prospects in the field of flexible wearable sensors. However, there are still challenges to stably apply conductive hydrogels in extreme environments and various aqueous conditions. To enable the application of conductive hydrogels across a wide temperature range and in multiple environments, it is necessary to consider comprehensive properties such as anti-swelling ability, flexibility, self-adhesiveness, stable linear sensing, and certain durability.

Defect engineering in cobalt-doped prussian blue to enhance sonocatalytic activities for anticancer treatment.

The effect of sonocatalysis on anticancer treatment is always restricted by rapid recombination of charge and low utilization of the ultrasonic cavitation effect. Herein, cobalt-doped prussian blue (PB) nanocubes were synthesized, and then they were etched by acidic solution to obtain amorphous Co-FePB@1h with abundant defects including: Fe/Co defects, Fe-(CN) vacancies, and dangling bonds. Both doping and defect engineering contribute to decreasing the band gap and promoting charge separation.

Calibration Transfer of Deep Learning Models among Multiple Raman Spectrometers via Low-Rank Adaptation.

While deep learning-enhanced Raman spectroscopy enables rapid sample analysis, model portability among spectrometers remains hindered by systematic interdevice variations. In this study, a Low-Rank Adaptation-based Calibration Transfer method (LoRA-CT) is proposed to perform parameter-efficient fine-tuning of deep learning models across spectrometers. By decomposing weight updates into low-rank matrices, LoRA-CT achieves superior calibration transfer with minimal samples, reducing trainable parameters by 600× compared to full parameter fine-tuning.

Foam separation of whey soybean protein with "microflower-templated" temperature-responsive Janus sheets as an efficient and recyclable foam stabilizer.

For recovering whey soybean protein (WSP) from soybean whey wastewater (SWW) in food industry, a foam separation method for separating WSP by using temperature-responsive Janus sheets (MF-JNSs-PN) as foam stabilizer was established. MF-JNSs-PN was prepared by grafting the temperature-responsive polymer PNIPAM onto one side of the sheet inorganic material using BSA@Cu(PO)-MF as the template. MF-JNSs-PN has a good ability to stabilize the foam due to inducing the hydrophilicity and hydrophobicity transition by adjusting the temperature.

Molecular basis and detection technologies of sweetness.

Enhancing food taste remains a pivotal focus of modern food science research and has drawn increasing attention in recent years. Among the fundamental components of food flavor, sweetness holds a position of utmost importance and its impact on consumers' sensory experiences is profound, which has driven extensive use of sweeteners as food additives for sweetness regulation in contemporary food industry. However, its underlying mechanisms are not yet fully understood, presenting numerous questions that warrant further investigation.

Iodine Enabled Mild 1,3-Hydroxyiodation of Arylcyclopropanes.

1,3-difunctionalized skeletons are important feedstocks and frequently appear in pharmaceuticals. However, effective and straightforward approaches to these scaffolds remain challenging. Herein, we reported a mild and efficient strategy for 1,3-hydroxyiodation, employing molecular iodine as both the promoter and iodinating agent.

Design and Fabrication of Flexible Silk Fibroin/Lanthanide Ion Membranes with Multifunctional Properties of Fluorescence, Humidity Sensitivity, and Conductivity.

Silk fibroin (SF)-based flexible electronic/photonic materials have gained great attention in wearable devices and soft sensors. However, it remains challenging to understand the molecular interaction mechanisms and subsequently fabricate SF-based flexible materials that exhibit fluorescence, humidity sensitivity, and conductivity properties. In this study, by incorporating lanthanide europium ion (Eu), the design and fabrication of a flexible, fluorescent, and conductive SF membrane was proposed.

Machine learning-guided design of a supramolecular armor for stable and functional perovskite quantum dots.

A machine learning-designed "supramolecular armor" imparts exceptional stability to perovskite quantum dots. A guanidinium crosslinker reinforces a β-cyclodextrin layer, creating a robust yet permeable interface that enables direct contact sensing in challenging aqueous environments.

Progress and Perspective on Heterogeneous Catalysis of Liquid Formic Acid Dehydrogenation: Coordination Structure Design, Activity Improvement, and Mechanism Insights.

Formic acid (FA) has attracted significant interest as a renewable liquid-phase hydrogen carrier. Hydrogen generation from FA decomposition is essential for the development of hydrogen economy. Designing highly efficient catalysts with different coordination environments for FA dehydrogenation is crucial for fuel-cell applications.

A Design for Achieving Robustness in Molecular Machines Based on Self-Assembled Pyrene Cavitands.

We designed a molecular switch based on a cavitand and pyrene. The controllable switching properties of the cavitand paired with flexible chains are some of the best combinations for achieving robustness in complex environments. A rigid chain cavitand was also synthesized as a control, and its single crystals with high molecular weights were obtained.

Additive-controlled chemodivergent multi-component domino reaction between salicylaldehydes and Morita-Baylis-Hillman (MBH) carbonates.

An unexpected additive-controlled chemodivergent multi-component domino reaction of salicylaldehydes with MBH carbonates has been skillfully developed. Interestingly, acid additives regulate the reaction to form functionalized cyclohexenes or natural coumarin derivatives. Notably, the coumarins were produced a novel phosphine-mediated α-umpolung/Wittig olefination/cycloaddition/lactonization/elimination cascade.

Measurement of protein non-covalent interactions in buffer and cells.

Nuclear magnetic resonance (NMR) serves as a powerful tool for studying both the structure and dynamics of proteins. The NOE method, alongside residual dipolar; coupling, paramagnetic effects, -coupling, and other related techniques, has reached a level of maturity that allows for the determination of protein structures. Furthermore, NMR relaxation methods prove to be highly effective in characterizing protein dynamics across various timescales.

An amphiphilic peptide with unnatural amino acids as an alignment medium for RDC measurements.

The multiple oligopeptides have been regarded as promising alignment media due to their structural diverseness and tendency for self-assembly in solution. Herein, an assembled amphiphilic peptide alignment medium, i.e.

Is high specific surface area essential for anode catalyst supports in proton exchange membrane water electrolysis?

Dispersing iridium onto high-specific-surface-area supports is a widely adopted strategy to maximize iridium utilization in anode catalysts of proton exchange membrane water electrolysis (PEMWE). However, here we demonstrate that the overall cell performance, including initial efficiency and long-term stability, does not benefit from the typical high specific surface area of catalyst supports. The conventional understanding that high iridium utilization on high-specific-surface-area supports increases activity holds only in aqueous electrolytes, while under the typical working conditions of PEMWE, the mass transport within the anode catalyst layers plays a more significant role in the overall performance.

Correction: Dual drug-loaded metal-phenolic networks for targeted magnetic resonance imaging and synergistic chemo-chemodynamic therapy of breast cancer.

Correction for 'Dual drug-loaded metal-phenolic networks for targeted magnetic resonance imaging and synergistic chemo-chemodynamic therapy of breast cancer' by Li Xia , , 2024, , 6480-6491, https://doi.org/10.1039/D4TB00462K.

Molecular engineering based on four-arm perylene diimide chromophores toward hypoxia-induced specific photothermal therapy.

Perylene diimide (PDI) radical anions have attracted increasing attention as hypoxia-responsive photothermal agents due to their strong near-infrared (NIR) absorption and efficient photothermal conversion. However, their biomedical application is often limited by aggregation-induced quenching and poor structural tunability. In this work, we report a rationally engineered four-arm PDI derivative (PDI-4Alky·4Cl) bearing terminal alkyne groups, which not only suppresses π-π stacking steric and electrostatic repulsion, but also serves as a versatile molecular scaffold for further functionalization.

Ni-Catalyzed and Pentafluorobenzoate-Leaving-Group-Enabled Stereoselective -Aryl Glycosylation.

Inspired by the excellent stereoinduction of palladium catalytic glycosylation with glycals via an inner-sphere pathway, a nickel-catalyzed, stereoselective -aryl glycosylation has been developed for glucals bearing a pentafluorobenzoate (PFB) group at the C3 position. The extremely electron-deficient nature of PFB not only endows stronger activity compared to the traditional leaving groups but also functions as an orientation group, presumably through the strong π-π interactions with the bipyridine ligand coordinated to the nickel center, thereby enabling the β-selective formation of a -aryl glycosidic bond with aryl iodides as glycosyl acceptors under mild conditions. This method features a broad substrate scope, high efficiency, and scalability, providing a general solution to the synthesis of challenging β--glycosides.

Polymer-based gene-drug co-delivery system effectively inhibits pathologic retinal neovascularization through dual anti-inflammatory and anti-neovascular actions.

Retinal neovascularization is one of the most prevalent fundus neovascular diseases, affecting vision and potentially leading to severe complications, such as retinal detachment or irreversible blindness. Current treatments primarily involve intravitreal injections (IVT) of anti-vascular endothelial growth factor (anti-VEGF) agents. However, such treatment often requires repeated injections, develop incomplete responses, and are associated with adverse effects.

A CuBiO/TiO p-n Heterojunction for Enhancing the Barrier Protection of a Nickel-Based Layer on the Magnesium Alloy.

Herein, CuBiO microspheres were first deposited on TiO nanotube arrays to develop a p-n CuBiO/TiO heterojunction by a facile hydrothermal protocol. The variations in the photoinduced open-circuit potential, photocurrent, and electrochemical parameters of the nickel-plated magnesium alloy (Mg/Ni) demonstrated the remarkably strengthened photoelectrochemical efficiency and photocathodic protection (PCP) capability caused by the CuBiO modification. This enhancement is attributed to establishing a built-in electric field and intensified light absorption in a broadened wavelength spectrum, confirmed by the valence band XPS and ultraviolet-visible spectra.