Intermittent fasting produces antidepressant-like effects by modulating dopamine D1 receptors in the medial prefrontal cortex.

Nutritional psychiatry has gained increasing attention, particularly in exploring dietary interventions for depression treatment. As a potential non-drug intervention, intermittent fasting (IF) has gradually attracted the interest of researchers, but its specific neurobiological mechanisms in depression remain unclear. The medial prefrontal cortex (mPFC) dopamine D1 receptors (Drd1) are significant in stress response and serve as a molecular target for rapid-acting antidepressants.

Research on underwater air layer retention and antifouling ability of Salvinia-inspired biomimetic materials.

Marine biofouling not only increases the navigation resistance of ships, accelerates the corrosion of metal substrates, but also hinders the healthy development of the marine economy. Inspired by the unique structure and function of Salvinia, we designed and fabricated biomimetic surfaces with superhydrophobic hairs and hydrophilic patches (SHHPs) using silicone rubber-graphene (SR-GN) and SR modified with polyacrylic acid (SR-PAA) composites. SHHPs can generate pinning effects underwater, forming an air layer as an environmentally friendly physical antifouling barrier.

Ring opening of donor-acceptor-type cyclopropene unveils electrophilic ketene with vinylogous [4 C + n] periselective cyclization mode.

Since its advent 120 years ago, the [2+n] coupling cyclization of ketene has been prevalently used for the synthesis of N- and O-heterocycles. In contrast, its vinylogous version, i.e.

HFKG-RFE: An algorithm for heterogeneous federated knowledge graph.

Federated learning ensures that data can be trained globally across clients without leaving the local environment, making it suitable for fields involving privacy data such as healthcare and finance. The knowledge graph technology provides a way to express the knowledge of the Internet into a form more similar to the human cognitive world. The training of the knowledge graph embedding model is similar to that of many models, which requires a large amount of data for learning to achieve the purpose of model development.

Semantics-Assisted Training Graph Convolution Network for Skeleton-Based Action Recognition.

The skeleton-based action recognition networks often focus on extracting features such as joints from samples, while neglecting the semantic relationships inherent in actions, which also contain valuable information. To address the lack of utilization of semantic information, this paper proposes a semantics-assisted training graph convolution network (SAT-GCN). By dividing the features outputted by the skeleton encoder into four parts and contrasting them with the text features generated by the text encoder, the obtained contrastive loss is used to guide the overall network training.

Microporous poly(aryl piperidinium) hydroxide exchange membranes with multi-directional branched structure for high performance fuel cells.

Hydroxide exchange membranes (HEMs) are important materials for energy conversion devices in hydroxide exchange membrane fuel cells (HEMFCs). This study details a series of multi-directional branched HEMs containing octaphenylcyclotetrasiloxane (OCSi). The OCSi structure allows for the establishment of continuous OH conducting channels within the membrane while addressing the prevailing trade-off between ionic conductivity and size/mechanical stability.

Study on Material Removal Mechanism of Non-Resonant Vibration-Assisted Scratching High-Volume Fraction SiCp/Al.

Aluminum-based silicon carbide (SiCp/Al) is a hard-to-process material. SiC particles are randomly distributed and have a unique structure, thus posing challenges during processing. These distinctions considerably affect the overall quality of machining.

Ionic liquid-assisted stabilization of MXene in polysaccharide-chitosan hydrogels with mechanical enhancement for catalytic and sensor applications.

In this study, a novel composite functional hydrogel was developed, integrating outstanding mechanical properties, remarkable catalytic activity, and highly sensitive sensing performance. Here, the dispersion behavior of TiCT(MXene) via ionic liquids was examined, focusing on the interplay between surface functional groups of MXene and IL. The study aims to elucidate the mechanisms governing dispersion stability.

Dual-channel fluorescent probe for simultaneously visualizing ONOO and viscosity in epilepsy, non-alcoholic fatty liver and tumoral ferroptosis models.

Intracellular peroxynitrite anion (ONOO) and viscosity play a major part in sustaining redox homeostasis, modulating substance transport and signal transduction. Abnormalities in these factors are closely associated with multiple physiological and pathological processes. Nevertheless, due to the absence of appropriate multifunctional fluorescent sensors, concurrent identification of ONOO and viscosity has not been achieved in many diseases, such as epilepsy and tumoral ferroptosis models.

A dual-path convolutional neural network combined with an attention-based bidirectional long short-term memory network for stock price prediction.

The complexities of stock price data, characterized by its nonlinearity, non-stationarity, and intricate spatiotemporal patterns, make accurate prediction a substantial challenge. To address this, we propose the DCA-BiLSTM model, which combines dual-path convolutional neural networks with an attention mechanism (DCA) and bidirectional long short-term memory networks (BiLSTM). This model captures deep information and complex dependencies within time-series data.

Therapeutic Potential of the Novel GLP-1 Receptor Agonist Semaglutide in Alcohol Use Disorder.

Alcohol use disorder (AUD) is a prevalent neuropsychiatric disorder with serious health and social consequences. However, few licensed and successful pharmacotherapies exist for heterogeneous and complex disorders such as AUD, and these are poorly utilized. Preclinical and clinical findings suggest that the glucagon-like peptide-1 (GLP-1) system, a gut-brain peptide, is involved in the neurobiology of addictive behaviors.

Structurally Engineering Multi-Shell Hollow Zeolite Single Crystals via Defect-Directed Oriented-Kinetics Transformation and Their Heterostructures for Hydrodeoxygenation Reaction.

Single-crystalline multi-shell hollow porous materials with high compartment capacity, large active surface area, and superior structural stability are expected to unlock tremendous potential across diverse critical applications. However, their synthetic methodology has not yet been well established. Here, we develop a defect-directed oriented-kinetics transformation approach to prepare multi-shell hollow aluminosilicate ZSM-5 zeolite (MFI) crystals with single-crystalline feature, hierarchical macro-/mesoporosity, controllable shell number, and high structural stability.

Waterborne Polyurethane-Stabilized Hydrogel Coating with Lubrication and Antibacterial Properties on Medical Catheters.

Medical catheters require lubrication and antimicrobial properties to reduce complications, such as tissue trauma and bacterial infections. Coating hydrogel on the catheter surface is a promising strategy; however, it usually faces the challenge of weak interfacial adhesion, thus leading to coating delamination or fracture and failure. Here, a waterborne polyurethane (WPU)-triggered surface bonding strategy was presented to construct hydrogel coatings, which involved two key steps: (i) coating a sticky WPU layer on the catheter surface and (ii) dip-coating the WPU-coated catheter with a monomer solution consisting of quaternary ammonium chitosan (QCS), sulfobetaine methacrylate (SBMA), -vinylpyrrolidone (NVP), and zinc sulfate heptahydrate (ZnSO·7HO) for growing the hydrogel layer by ultraviolet initiation.

Fe intercalated hierarchical structured hydrated vanadate cathode for flexible iron ion hybrid supercapacitor.

Energy storage devices are the core hub in constructing the modern energy system and have become an indispensable factor in driving the development of new electronic devices. In this work, we synthesized a flexible cathode of Fe intercalated VO·3HO (VOH) on carbon cloth (FeVOH@CC) and explored an advanced iron ion hybrid supercapacitor (IIHS). The presence of V/V electrons in FeVOH@CC enhances the material's conductivity, while Fe acts as a stabilizing pillar to accommodate structural expansion and contraction, thereby ensuring improved ion diffusion dynamics and cycling stability.

Research on Algorithm for Feature Extraction of Laryngoscope Image Distribution and Texture Fusion.

Purpose: In the context of rapid development of modern medical technology, the explosive growth of medical data has imposed a heavy diagnostic burden on professional physicians. Especially in the field of computer-assisted treatment research on laryngoscope imaging data, existing studies are still insufficient, which prompts this study to develop a new feature extraction and classification method. The purpose of this study is to improve the accuracy and efficiency of diagnosis for laryngopharyngeal reflux disease by using computer-assisted treatment technology and laryngoscope imaging data and drug treatment results.

Nickel-Catalyzed 1,1-Carboboration of Polysubstituted Internal Alkenes.

Herein, we report a nickel-catalyzed 1,1-carboboration of di- and trisubstituted alkenyl boronates through a chain-walking strategy. This reaction effectively addresses the polarity-mismatch problem via ligand control, enabling the coupling of various carbon-based electrophiles while accommodating a broad range of functional groups. The approach yields diverse tetrasubstituted carbon -diboronate derivatives with exceptional regioselectivity.

Calcium alginate aerogels doped with polypyrrole/titanium dioxide nanoparticles for photodegradation of congo red dye.

Generally, semiconductor photocatalyst can only absorbed ultraviolet light and easily reunited in the using process, which affected their catalytic efficiency. In this work, the calcium alginate/polypyrrole/titanium dioxide (CA/PPy/TiO) aerogel was prepared to photodegrade Congo red (CR) dye. The sensitization of TiO with PPy enabled energy absorption in visible light.

Emerging Multifunctional Wearable Sensors: Integrating Multimodal Sweat Analysis and Advanced Material Technologies for Next-Generation Health Monitoring.

Sweat, a noninvasive and readily accessible biofluid, offers significant potential in health monitoring through its diverse biomarker profile, including electrolytes, metabolites, and hormones, which reflect physiological states in real time. Multimodal wearable sensors, integrating chemical, physical, and thermal sensing capabilities, have emerged as transformative tools for capturing these biomarkers alongside additional physiological signals. By combining advanced materials such as hydrogels, MXenes, and graphene with innovative structural designs, these sensors enable simultaneous monitoring of biomarkers (e.

Mechanistic and adsorption kinetics study of sulfonated activated carbon enhanced starch-based aerogel for high efficient adsorption of cationic and anionic dyes.

Starch-based aerogels, with their low density, high porosity, and high specific surface area, show potential for application in dye adsorption. However, most of the current starch-based aerogels exhibited limitations, such as limited adsorption capacity and poor ability to selective treatment in complex dye wastewater. In this study, acrylic acid (AA) and allyl sulfonic acid sodium salt (AS) were grafted onto the carboxymethyl starch sodium (CMS) backbone via UV-induced radical polymerization, and combined with sulfonated activated carbon (SAC) to prepare a CAA/SAC starch-based aerogel with low density (0.

Oxygen-Sensitive Nanomaterials Synthesized in an Open System: Water-Triggered Nucleation and Its Controllability in the Growth Process.

A novel method has been developed for synthesizing the oxygen-sensitive nanomaterial WO, utilizing 1,3-propanediol as a solvent, with water-triggered nucleation and controllable crystal growth in an open system. The amount of water addition was precisely investigated for the effect of the crystal growth process. Furthermore, the incorporation of 2,5-furandicarboxylic acid into the process led to the successful preparation of a functionalized nanocomposite polyester, WO/poly(propylene 2,5-furandicarboxylate) (PTF), through in situ polymerization, exhibiting superior thermal insulation properties.

Psychological Fatigue or Satisfaction? The Impact of Online Office App Use on Job Performance: Differentiating Work-Related and Non-Work-Related Contexts.

Media psychological fatigue, a common negative behavior among employees using online office applications (apps), has a significant impact on job satisfaction and performance. This study explores the influence of online office app use on job performance, differentiating between work-related and non-work-related contexts, based on the Uses and Gratifications Theory and the Stimulus-Organism-Response Theory. Data were collected from 418 employees in 11 enterprises in mainland China through random sampling.

Carboxymethyl cellulose sodium modified poly(acrylic acid) and organic montmorillonite nanocomposite hydrogels with excellent purification ability for cationic dye wastewater.

Poly(acrylic acid) (PAA) based hydrogels have attracted substantial attention in water treatment due to their adsorption character, but their loose internal structure and lack of adsorption sites limit their application. Organic montmorillonite (OMMT) has a high specific surface area, but its dispersion is inadequate, making it difficult to apply in composite materials. Therefore, this study uses sodium carboxymethyl cellulose (CMCNa) as a modifier to improve the dispersion of OMMT in the hydrogel system, thereby enhancing the adsorption performance of the nanocomposite hydrogels.

Anion-Vacancy Activated Vanadium Sulfoselenide With In-Plane Heterostructure Enabling Durable and Wide-Temperature Zinc-Ion Batteries.

Zinc-ion batteries (ZIBs) represent a promising energy-storage device, which has remarkable merits in terms of cost-effectiveness, high safety, and environmental sustainability. Transition metal chalcogenides are emerging cathode materials for ZIBs due to their high theoretical capacity and large interlayer spacing. Nevertheless, their application faces critical challenges of sluggish reaction kinetics and huge volume variation.

The natural variation allele OsGSW3.2 in Oryza rufipogon is involved in brassinosteroid signaling and influences grain size and weight.

Oryza rufipogon is the ancestor of cultivated rice and harbors many elite genes; thus, this plant is an important germplasm for improving rice varieties. Grain size is an important factor in determining rice yield and quality. In this study, we identified a natural variation allele from the O.

Edible ginseng-derived exosomes as drug delivery vehicles reduce the dose and improve the anti-cancer effect of CDDP.

Nanotechnology and nanomaterials have emerged as promising tools for the delivery of anti-tumor drug cisplatin (CDDP). However, concerns exist regarding potential toxicity and cost-effectiveness, limiting their clinical applications. In contrast, plant-derived exosomes (PDEs), as natural nanovesicles, offer significant advantages as drug delivery carriers due to their large-scale production, biocompatibility, and ability to efficiently transport therapeutic drug across cellular barriers.