Publications by authors named "Zi-Xiang Li"

Strange-metal behavior has been observed in superconductors ranging from cuprates to pressurized nickelates, but its relationship to unconventional superconductivity remains elusive. Here, we perform operando superfluid density measurements on ion-gated FeSe films. We observe a synchronized evolution of the superconducting condensate and the strange-metal phase with electron doping, from which a linear scaling between zero-temperature superfluid density and strange-metal resistivity coefficient is further established.

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A quantum spin liquid (QSL) is an exotic insulating phase with emergent gauge fields and fractionalized excitations. However, the unambiguous demonstration of the existence of a QSL in a "nonengineered" microscopic model (or in any material) remains challenging. Here, using numerically exact sign-problem-free quantum Monte Carlo simulations, we show that a QSL arises in a nonengineered electron-phonon model.

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In unconventional superconductors such as cuprates and iron pnictides and chalcogenides, phase stiffness-a measure of the energy cost associated with superconducting phase variations-governs the formation of superconductivity. Here we demonstrate a vector current technique enabling in-situ angle-resolved transport measurements to reveal anisotropic phase stiffness in infinite-layer nickelate superconductors. Pronounced anisotropy of in-plane resistance manifests itself in both normal and superconducting transition states, indicating crystal symmetry breaking.

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The conventional Kibble-Zurek mechanism and the finite-time scaling provide universal descriptions of the driven critical dynamics from gapped initial states based on the adiabatic-impulse scenario. Here we investigate the driven critical dynamics in two-dimensional Dirac systems, which harbor semimetal and Mott insulator phases separated by the quantum critical point triggered by the interplay between fluctuations of gapless Dirac fermions and order parameter bosons. We find that despite the existence of the gapless initial phase, the driven dynamics can still be captured by the finite-time scaling form.

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The exotic quantum states emerging in the quasicrystal (QC) have attracted extensive interest because of various properties absent in the crystal. In this Letter, we systematically study the Holstein model at half filling on a prototypical structure of QC, namely rhombic Penrose lattice, aiming at investigating the superconductivity (SC) and other intertwined ordering arising from the interplay between quasiperiodicity and electron-phonon interaction. Through unbiased sign-problem-free determinant quantum Monte Carlo simulations, we reveal the salient features of the ground state phase diagram.

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In the zoo of emergent symmetries in quantum many-body physics, the previously unrealized emergent spacetime supersymmetry (SUSY) is particularly intriguing. Although it was known that spacetime SUSY could emerge at the (1+1)d tricritical Ising transition, an experimental realization is still absent. In this Letter, we propose to realize emergent spacetime SUSY using reconfigurable Rydberg atom arrays featuring two distinct sets of Rydberg excitations, tailored for implementation on dual-species platforms.

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Article Synopsis
  • - The disappearance of superconductivity in overdoped cuprates is debated, and this study uses scanning tunneling spectroscopy to explore quasiparticle interference in BiSrCuO at varying hole densities.
  • - As doping increases, a unique arc-like quasiparticle interference pattern develops, even at zero bias, indicating a shift in behavior incompatible with traditional models of d-wave superconductivity.
  • - The findings suggest that a new type of normal fluid arises from particle interactions, leading to a decrease in superfluid density and a suppression of superconductivity in overdoped cuprates.
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Objective: We aimed to investigate the effect of Lycium barbarum polysaccharide (LBP) on the proliferation and differentiation of osteoblasts in postmenopausal individuals with osteoporosis using in vitro cell experiments.

Methods: We assessed the effect of long-term LBP consumption on the intestinal metabolites of individuals using a simulation of the human intestinal microbiota ecosystem. We also tested the capacity of LBP in proliferating MC3T3-E1 cells using the cell counting kit-8 (CCK-8) method and analyzed the effect of intestinal metabolites on the osteogenic differentiation of MC3T3-E1 cells by testing bone metabolism viability with relevant indicators.

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Exotic quantum phases and phase transition in the strongly interacting Dirac systems have attracted tremendous interests. On the other hand, non-Hermitian physics, usually associated with dissipation arising from the coupling to environment, emerges as a frontier of modern physics in recent years. In this Letter, we investigate the interplay between non-Hermitian physics and strong correlation in Dirac-fermion systems.

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  • Researchers are exploring complex physics in strongly correlated systems using advanced quantum Monte Carlo simulations to understand different phases that emerge based on interaction strength and the number of components (N) in an SU(N) fermionic model.
  • The study found that for small N values (like 2 and 3), the system displays antiferromagnetic order, while for large N, staggered valence bond solid order becomes significant.
  • The research also uncovers a Mott insulating phase characterized by the competition between staggered and columnar orders, without spontaneous symmetry breaking, suggesting potential pathways to identify exotic states like quantum spin liquids in real materials.
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Understanding strongly correlated quantum materials, such as high-T_{c} superconductors, iron-based superconductors, and twisted bilayer graphene systems, remains as one of the outstanding challenges in condensed matter physics. Quantum simulation with ultracold atoms in particular optical lattices, which provide orbital degrees of freedom, is a powerful tool to contribute new insights to this endeavor. Here, we report the experimental realization of an unconventional Bose-Einstein condensate of ^{87}Rb atoms populating degenerate p orbitals in a triangular optical lattice, exhibiting remarkably long coherence times.

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  • (-)-Adenophorone (1) is a unique tricyclic compound derived from the plant Eupatorium adenopharum, and its structure was confirmed through advanced analytical techniques including X-ray crystallography.* -
  • A total synthesis of (-)-Adenophorone was performed, efficiently synthesizing the related compound (+)-euptox A (2) in just eight steps using commercially available materials and demonstrating effective control over molecule orientation.* -
  • The synthesized (-)-Adenophorone exhibited significant neuroprotective properties in tested cell lines, supporting its potential therapeutic application and providing insights into its biosynthetic pathway.*
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  • Beta-amyloid protein (Aβ) plays a crucial role in Alzheimer's disease, and N-linoleyltyrosine (NITyr) shows promise as a neuroprotective agent against Aβ-induced damage in neurons.
  • NITyr effectively reduces cell death, enhances BDNF protein levels, activates autophagy-related proteins, and promotes a beneficial signaling pathway involving p-CREB and protein expressions related to neuron survival.
  • The neuroprotective effects of NITyr are dependent on its ability to induce autophagy, which is mediated through the CB/AMPK/mTOR/ULK1 signaling pathway, as blocking these pathways diminishes its protective benefits.
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Antiferromagnetism (AFM) such as Néel ordering is often closely related to Coulomb interactions such as Hubbard repulsion in two-dimensional (2D) systems. Whether Néel AFM ordering in two dimensions can be dominantly induced by electron-phonon couplings (EPC) has not been completely understood. Here, by employing numerically exact sign-problem-free quantum Monte Carlo (QMC) simulations, we show that bond Su-Schrieffer-Heeger (SSH) phonons with frequency ω and EPC constant λ can induce AFM ordering for a wide range of phonon frequency ω>ω_{c}.

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Osteoarthritis (OA), characterized by chondrocyte apoptosis and disturbance of the balance between catabolism and anabolism of the extracellular matrix (ECM), is the most common age-related degenerative joint disease worldwide. As sleep has been found to be beneficial for cartilage repair, and circular RNAs (circRNAs) have been demonstrated to be involved in the pathogenesis of OA, we performed RNA sequencing (RNA-seq), and found circRNA3503 was significantly increased after melatonin (MT)-induced cell sleep. Upregulation of circRNA3503 expression completely rescued the effects of interleukin-1β (IL-1β), which was used to simulate OA, on apoptosis, ECM degradation- and synthesis-related genes.

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Functional healing of tendon injuries remains a great challenge. Small extracellular vesicles (sEVs) have received attention as pro-regenerative agents. H19 overexpression could bring tendon regenerative ability, but the mechanism is still not fully elucidated, and reliable method for delivery of long non-coding RNAs (LncRNAs) was demanded.

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The prognosis for osteosarcoma (OS) continues to be unsatisfactory due to tumor recurrence as a result of metastasis and drug resistance. Several studies have shown that Ewing sarcoma associated transcript 1 (EWSAT1) plays an important role in the progression of OS. Exosomes (Exos) act as important carriers in intercellular communication and play an important role in the tumor microenvironment, especially in tumor-induced angiogenesis.

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Background: The treatment outcome of transarterial chemoembolization (TACE) in unresectable hepatocellular carcinoma (HCC) varies greatly due to the clinical heterogeneity of the patients. Therefore, several prognostic systems have been proposed for risk stratification and candidate identification for first TACE and repeated TACE (re-TACE).

Aim: To investigate the correlations between prognostic systems and radiological response, compare the predictive abilities, and integrate them in sequence for outcome prediction.

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The recent discovery of the interfacial superconductivity (SC) of the BiTe/FeTe heterostructure has attracted extensive studies due to its potential as a novel platform for trapping and controlling Majorana fermions. Here we present studies of another topological insulator (TI)/FeTe heterostructure, SbTe/FeTe, which also has an interfacial 2-dimensional SC. The results of transport measurements support that reduction of the excess Fe concentration of the FeTe layer not only increases the fluctuation of its antiferromagnetic (AFM) order but also enhances the quality of the SC of this heterostructure system.

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Background: To investigate the feasibility and safety of computed tomography-magnetic resonance imaging (CT-MRI) fusion-guided iodine-125 seed implantation for a single malignant brain tumor.

Methods: From November 2015 to October 2016, 12 patients with a single malignant brain tumor were treated with permanent iodine-125 seeds implantation. CT-MRI fusion images were used to make the preoperative treatment plan, intraoperative dose optimization, postoperative verification, and tumor response follow-up.

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In this paper, we apply the K-theory to classify topological trivial fermionic phases which, nonetheless, host symmetry-protected non-trivial defects. An important implication of our work is that the existence of Majorana zero mode in the vortex core is neither a necessary nor a sufficient condition for the superconductor in question being topologically non-trivial.

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No definitive evidence of spacetime supersymmetry (SUSY) that transmutes fermions into bosons and vice versa has been revealed in nature so far. Moreover, the question of whether spacetime SUSY in 2 + 1 and higher dimensions can emerge in generic lattice microscopic models remains open. Here, we introduce a lattice realization of a single Dirac fermion in 2 + 1 dimensions with attractive interactions that preserves both time-reversal and chiral symmetries.

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Article Synopsis
  • A doped spin-1/2 ladder with specific magnetic couplings behaves as a unique topological Luttinger liquid, distinct from standard models.
  • Turning on spin anisotropy can shift the system to a simpler, trivial Luttinger liquid phase, while both phases still show superconducting pair correlations.
  • The transition between these two phases is marked by a closing spin gap and has potential implications for understanding superconductivity in certain metallic systems.
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Proposed as a fundamental symmetry describing our Universe, spacetime supersymmetry (SUSY) has not been discovered yet in nature. Nonetheless, it has been predicted that SUSY may emerge in low-energy physics of quantum materials such as topological superconductors and Weyl semimetals. Here, by performing state-of-the-art sign-problem-free quantum Monte Carlo simulations of an interacting two-dimensional topological superconductor, we show convincing evidence that the N=1 SUSY emerges at its edge quantum critical point (EQCP) while its bulk remains gapped and topologically nontrivial.

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Forkhead box protein M1 (FoxM1) is aberrantly expressed in several types of human malignancy, and serves an important role in tumor metastasis. Epithelial‑mesenchymal transition (EMT) of cancer cells has been associated cancer metastasis; however, the implication of FoxM1 in EMT and its putative roles in the regulation of cancer metastasis remain to be elucidated. In the present study, the expression of FoxM1, Snai1 and E‑cadherin in hepatocellular carcinoma (HCC) cell lines with various metastatic potentials, and in normal liver cells, was investigated using western blot analysis and reverse transcription‑quantitative polymerase chain reaction.

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Synopsis of recent research by authors named "Zi-Xiang Li"

  • - Zi-Xiang Li's recent research spans multiple interdisciplinary fields, focusing on quantum physics, materials science, and biological applications, with significant contributions such as the exploration of exotic quantum phases in strongly interacting Dirac fermion systems and the emergence of competing orders in SU(N) fermions.
  • - In the realm of condensed matter physics, his studies demonstrate innovative insights into superconductivity in overdoped cuprates through quasiparticle interference patterns, and the experimental realization of a Bose-Einstein condensate, shedding light on complex quantum materials.
  • - Additionally, Li has made impactful advancements in biomedical research, investigating the effects of natural compounds like Lycium barbarum polysaccharide on osteoporosis and neuroprotective agents against Alzheimer’s disease, highlighting the convergence of physicochemical principles and health sciences.