Advances in the application of stress-resilient and growth-enhancing seed coating and pelleting technology for ecological restoration.

The core mechanism of stress-resilient and growth-enhancing seed coating and pelleting technology involves applying a multifunctional protective layer to seeds with liquid or powder coating agents. This layer enhances seed resilience to environmental stressors, making the technology a promising tool for ecological restoration. We reviewed the theoretical basis and development of the technology, including seed coating principles, the selection and optimization of active and inert materials, and composite coatings, and advances in pelleting techniques.

Inflammation-nutrition biomarker model for survival prediction in lung cancer patients with concurrent tuberculosis.

Objectives: To explore the prognostic value of eight inflammation-nutrition biomarkers in patients with lung cancer and tuberculosis as no multidimensional prognostic models for this comorbid population are available currently.

Methodology: A retrospective study included 100 patients with lung cancer and tuberculosis admitted to a tertiary hospital from October 2019 to October 2024. Eight inflammation-nutrition markers (NLR, PLR, SII, LMR, PNI, HALP, HRR, ALB/GLB) were chosen as predictors while overall survival (OS) was the major event.

Glycosidic acids with α-glucosidase inhibitory activity as the alkaline hydrolysis products of resin glycoside fractions from Convolvulus tricolor and Ipomoea biflora.

Alkaline hydrolysis of the resin glycoside fractions of Convolvulus tricolor and Ipomoea biflora yielded three glycosidic acids (1-3). Contrilic acid A (1), a hexasaccharide glycosidic acid with a 3S,11S-dihydroxytetradecanoic acid as the aglycone, was isolated from Convolvulus tricolor, while a tetrasaccharide ipomofic acid A (2) and pentasaccharide operculinic acid A (3) were obtained from Ipomoea biflora, and were identified to possess a 11S-hydroxyhexadecanoic acid as the aglycone. Their structures were thoroughly established by the spectroscopic data and chemical evidences.

Identification of Immune Hub Genes in Obese Postmenopausal Women Using Microarray and Single-Cell RNA Seq Data.

Obesity is characterized by a chronic state of low-grade inflammation. Investigating immune-critical genes and their biological functions in the adipose tissue of postmenopausal obese women is crucial for elucidating the underlying mechanisms of immune dysregulation associated with obesity. In this study, microarray (GSE151839) and single-cell RNA-seq (GSE176171) datasets were obtained from the Gene Expression Omnibus (GEO).

[Application of mixed methods systematic review in the evidence-based evaluation of acupuncture and moxibustion].

The meta-analysis is generally employed to synthesize data in the conventional systematic review of acupuncture and moxibustion, in which, the quantitative analysis is predominant. Mixed methods systematic reviews of acupuncture (MMSR-A) adopts PICOS and SPIDER to formulate the questions; the research objects are expanded to qualitative and mixed studies. This mixed methods use the mixed methods appraisal tool (MMAT) for the methodology quality evaluation or the quality assessment tool of the Joanna Briggs Institue (JBI), and a variety of mixed analytic methods.

Further new resin glycosides from Convolvulus tricolor seeds and their neuroprotective activities.

Resin glycosides, the characteristic constituents of family Convolvulaceae, are a kind of new and complex glycolipids with diversified biological activities. In the present study, the ethanolic extract of Convolvulus tricolor seeds were purified by various separation methods, leading to the isolation of seven new resin glycosides (1-7). Their structures were established as glycosidic acids methyl esters by extensive spectroscopic analyses and chemical evidences, and were considered to be generated via methyl esterification of natural resin glycosides during the NH silica gel chromatography.

Safety and Efficacy of Grapefruit Juice Combined With Low-Dose Venetoclax in AML Patients Ineligible for Intensive Chemotherapy.

Purpose: Venetoclax in combination with hypomethylating agents (HMAs) has become the standard treatment for acute myeloid leukemia (AML) patients ineligible for intensive chemotherapy. However, its high cost limits its accessibility in low- and middle-income countries. This study aims to evaluate the efficacy and safety of grapefruit juice combined with low-dose venetoclax and azacitidine as a feasible cost-reduction strategy.

Choroid plexus enlargement correlates with subcortical tau deposition in progressive supranuclear palsy.

Objective: The choroid plexus (CP) has gained renewed attention for its role in waste clearance in neurodegenerative disorders. However, its involvement in progressive supranuclear palsy (PSP) remains unclear. This study aimed to investigate CP volume changes in patients with PSP compared to Parkinson's disease (PD), and explore its relationship with tau deposition in PSP patients.

A novel radiation protection method for miniaturized MIMO mobile terminal antenna design based on metamaterials.

In this article, we propose an innovative approach to reduce radiation dose absorption inside human head tissues by shrinking the multiple-input multiple-output (MIMO) terminal geometric area. Initially, we employ COMSOL software to design a MIMO mobile terminal antenna that meets 2G, 3G, 4G, and 5G communication requirements. Through adding the decoupling unit, its geometric area reduces from 58 × 120 mm² to 44 × 80 mm², and its simulations and measurements indicate that the miniaturized MIMO mobile terminal antenna exhibits good radiation performance.

Hippocampal Subfield Vulnerability and Functional Connectivity in Cognitive Decline: a Comparison Between Parkinson's Disease and Mild Cognitive Impairment.

Purpose: To investigate the shared and distinct alterations in hippocampal subfield atrophy and functional connectivity (FC) in Parkinson's disease (PD) with normal cognition (PD-NC), PD with mild cognitive impairment (PD-MCI) and unspecified MCI (U-MCI).

Methods: A total of 294 participants were included from two centers (30 PD-NC, 86 PD-MCI, 76 U-MCI, and 102 healthy controls (HC)). Comparisons of hippocampal subfield volumes were conducted among groups.

Interconnected Pathways of Alzheimer's Disease and Osteoporosis: A Review of Genetic, Hormonal, and Environmental Influences.

Alzheimer's disease (AD) and osteoporosis (OP) are both age-related multifactorial degenerative diseases that share overlapping pathogenic mechanisms. While genetic factors contribute significantly to their onset and progression, environmental influences also play a crucial role. However, identifying the shared environmental factors and genetic architecture underlying the co-pathogenesis of AD and OP remains a significant challenge.

Prognostic potential of neutrophil-to-lymphocyte ratio for adverse outcomes in dilated cardiomyopathy: a retrospective cohort study.

Neutrophil-to-lymphocyte ratio (NLR), as a novel inflammatory marker, has been shown to be associated with the severity and prognosis of various cardiovascular diseases. The aim of this study was to investigate whether NLR can serve as a biomarker for adverse outcomes and prognostic value in patients with dilated cardiomyopathy (DCM). This was a retrospective analysis of 666 consecutive patients with DCM who were admitted to our center for the first time.

Controlins I-X, Resin Glycosides from the Seeds of and Their Biological Activities.

Ten new resin glycosides, controlins I-X (-), were isolated from the seeds of . Their structures were established by spectroscopic analysis as well as by chemical means. Compounds were identified as glycosidic acid methyl esters, considered as artifacts generated via transesterification with MeOH from natural resin glycosides.

Cross-sectional and longitudinal association of sleep patterns and aneurysmal vulnerability biomarkers on high-resolution magnetic resonance vessel wall imaging.

Background: Aneurysm wall enhancement (AWE) on vessel wall imaging (VWI) scans is a robust biomarker for aneurysmal vulnerability. This study aimed to explore the association of different sleep patterns with AWE and other vulnerability features.

Methods: Patients with unruptured intracranial aneurysms were prospectively recruited.

Structure-based development of N-Arylindole derivatives as Pks13 inhibitors against Mycobacterium tuberculosis.

Targeting the biosynthetic pathway of mycolic acid is highly attractive to researchers in the field of novel anti-tubercular drug development. Pks13-TE is an essential catalytic component in the last assembling step of mycolic acid, and the co-crystal structures of the Pks13-TE-inhibitor complex provide insight into ligand recognition. Based on a structure-guided strategy, N-aryl indole derivatives were designed, synthesized, and evaluated for their antitubercular activities.

The value of D-dimer in the prognosis of dilated cardiomyopathy: a retrospective cohort study.

D-dimer is a biomarker of coagulation and fibrinolytic system activation in response to the hypercoagulable state of the body. The research aimed to analyze the value of D-dimer in the prognosis of patients with dilated cardiomyopathy (DCM). Patients admitted to our center for the first time with DCM were enrolled consecutively.

[Characteristics of Phytoplankton Community Structure in Lakes of Wetlands Dominated by Different Aquatic Plants and Its Driving Factors].

In wetland ecosystems, small shallow lakes are critical transition zones of land and water, which are usually dominated by aquatic plants with different growth forms. However, the differences and key influencing factors of phytoplankton communities in shallow lakes dominated by different aquatic plants are unclear. On this basis, nine surveys were conducted at five sampling sites of three lakes in Zhangye National Wetland Park from June to November in 2022, which were respectively dominated by the emergent （LL）, the submerged （CL）, and the floating-leaved （SL）.

Two-dimensional viologen-based lanthanide coordination polymers as multi-stimuli responsive materials to light and amines with a fluorescence response.

Integrating multi-stimuli response properties in one molecule is challenging. This study presents two 2D polymers, [(Bpydp)Ln(HO)(BDC)]·NO·2HO (Ln = Eu(1), Tb(2)), exhibiting rapid photo-responsiveness and the ability to detect specific small-molecule amines. In particular, complex 1 combines the functions of inkless printing, amine detection, anti-counterfeiting, and fluorescence recognition.

On-demand removable hydrogel film derived from gallic acid-phycocyanin and polyvinyl alcohol for fruit preservation.

Postharvest spoilage of fruits accounts for significant losses ranging between 20 %-30 %, leading to considerable resource wastage and economic downturns. The development of an effective fresh-keeping packaging material is of paramount importance. This study introduces an innovative on-demand removable active fruit fresh-keeping film (GPP), created by embedding a GP (gallic acid-phycocyanin) fiber mesh hydrogel with functional properties into a polyvinyl alcohol (PVA) matrix.

[Advances in Research of the Effects and Mechanisms of Polyethylene Microplastics on Soil Nitrogen Transformation].

In the agricultural lands of China, polyethylene is the main component of microplastics （MPs）, with characteristics such as small size, wide distribution, easy accumulation, and difficult degradation. Therefore, it may have an impact on the elemental cycling process of the soil. On the basis of reviewing the key literatures in the past few years, this study systematically analyzed and summarized the key factors and processes of the polyethylene microplastics （PE-MPs） affecting soil nitrogen transformation.

Current research of Assisted Reproductive Technology for women with early endometrial cancer and atypical endometrial hyperplasia after conservative treatment.

As the incidence of endometrial cancer (EC) and atypical endometrial hyperplasia (AEH) has been increasing, and has shown young trend. It is crucial to study the fertility-preserving treatment of endometrial lesions and fertility-promoting protocols. Age, obesity, and irregular ovulation are not only high-risk factors for endometrial lesions but also key factors affecting female fertility.

Marital concerns of long-term hospitalised patients with diagnosed schizophrenia: A descriptive phenomenological study.

Marital concerns can trigger emotional stress, especially among long-term hospitalised individuals diagnosed with schizophrenia, significantly affecting their treatment and recovery. Unfortunately, rehabilitation programs tend to overlook the marital needs of individuals with diagnosed schizophrenia. This research aimed to investigate the content related to marital concerns of Chinese individuals diagnosed with schizophrenia who were undergoing extended hospitalisation.

Development and validation of a risk model for intracardiac thrombosis in patients with dilated cardiomyopathy: a retrospective study.

Intracardiac thrombosis is a severe complication in patients with non-ischemic dilated cardiomyopathy. This study aims to develop and validate an individualized nomogram to evaluate the risk of intracardiac thrombosis in patients with non-ischemic dilated cardiomyopathy. This retrospective study included patients diagnosed with dilated cardiomyopathy at first admission.