Application of stereotactic radiotherapy in the treatment of cardiovascular diseases through sympathectomy.

Sympathectomy, as an emerging treatment method for cardiovascular diseases, has received extensive attention in recent years. Stereotactic radiotherapy (SRT), a precise and noninvasive therapeutic technique, has gradually been introduced into interventions targeting the sympathetic nervous system and has shown promising prospects in the management of cardiovascular conditions. Using three-dimensional imaging, SRT can accurately localize sympathetic ganglia and deliver high-energy radiation to disrupt nerve fibers, thereby achieving effects similar to conventional sympathectomy while reducing surgery-related complications and shortening recovery time.

Path analysis of medication adherence in schizophrenia patients based on the extended theory of planned behavior: A cross-sectional study.

Background: Medication adherence is a significant challenge among community-dwelling patients with schizophrenia. Understanding the influencing factors through the lens of behavioral theory can provide valuable guidance for designing effective interventions to improve medication adherence.

Objectives: This study aimed to identify the factors associated with medication adherence and the underlying mechanisms, based on the extended Theory of Planned Behavior (TPB), among community-dwelling patients with schizophrenia in China.

Method and application of stability prediction model for rock slope.

Slope instability is a prevalent dynamic disaster encountered in the construction of geotechnical engineering projects. Intelligent detection and early warning systems serve as crucial measures for preventing and controlling slope instability. To accurately and efficiently predict the stability state of slopes, we propose a combined model that integrates the Newton-Raphson optimization algorithm (NRBO) with an optimized extreme gradient boosting tree (XGBoost).

Thermally Activated Delayed Fluorescence-Guided Photodynamic Therapy Through Skeleton-Homologous Nanoparticles: a Rational Material Design for High-Efficient and High-Contrast Theranostics.

Although photoluminescence imaging-guided photodynamic therapy (PDT) is promising for theranostics, it easily suffers from tissue autofluorescence and PDT photoproducts. To develop time-resolved imaging (TRI)-guided PDT with long-lived emission pathways, like thermally activated delayed fluorescence (TADF), is urgent but challenging, because of the triplet competition between radiative transition and reactive oxygen species (ROS) production. Herein, skeleton-homologous nanoparticles are designed and constructed to address this dilemma, thereby achieving in vivo TRI-guided PDT for the first time.

The role of family caregiving in the management of individuals with mental illnesses and the outcome of family-based interventions for mental illnesses in China: a scoping review.

The effects of China's rapid economic development and urbanisation on family caregivers' responsibilities for providing essential practical, social, and psychological support to family members with mental illnesses are unclear. This scoping review identified 176 relevant studies published from 1 January 2000 to 31 December 2023 in six English-language and three Chinese-language databases. Most studies focus on family caregiving for individuals with schizophrenia (63 studies), autism (40 studies), or dementia (39 studies).

Prediction model of water inrush risk level of coal seam floor based on KPCA-DBO-SVM.

To predict the risk of water inrush from coal seam floor more effectively, a prediction model of water inrush risk level of coal seam floor based on KPCA-DBO-SVM is proposed. Firstly, the risk level of water inrush of coal seam floor is graded based on the influencing factors of water inrush from coal seam floor which are determined by data of water inrush accident and related literature, and probability of water inrush in working face. Secondly, Kernel Principal Component Analysis (KPCA) is used to reduce the dimension of high-dimensional features of the influencing factors, Then, results of feature extraction are input into the DBO-SVM model.

Tragus Nerve Stimulation Attenuates Postural Orthostatic Tachycardia Syndrome in Post COVID-19 Infection.

Background: Postural orthostatic tachycardia syndrome (POTS) is characterized by symptoms of orthostatic intolerance and is frequently observed in post-COVID conditions.

Objectives: We conducted controlled, prospective, and randomized clinical trials to explore the potential therapeutic benefits of low-level tragus stimulation (LL-TS) in patients with POTS following COVID-19 infection.

Methods: This study enrolled 57 participants with confirmed post-acute COVID-19 who had been diagnosed with POTS.

Sulfur Lone Pairs Open Avenues for π* → n Orange-to-Red TADF and OLEDs.

It is always important and fascinating to explore new organic emitters that exploit unconventional pathways to unveil their emission with unique properties, such as thermally activated delayed fluorescence (TADF). In this study, we report that the rarely explored sulfur lone pair (n) is a promising alternative, where the correlated π* → n emission can be used to attain strong TADF and thus practical OLEDs. The designed strategy incorporates several key concepts (Figure 1a), in which the persulfide aromatic spirocycle enhances spin-orbit coupling, thereby increasing the intersystem crossing rate.

Medication adherence and needs among patients with schizophrenia in China: a qualitative study.

Objectives: To explore the factors influencing medication adherence and the medication needs of patients with schizophrenia when living in a community in China.

Design: A qualitative study.

Setting: Community and psychiatric ward in Zhuhai city, Guangdong province.

Case Report: Left ventricular assist device implantation combined with cryoballoon ablation for ventricular tachycardia.

We report a case of a patient with dilated cardiomyopathy who experienced recurrent ventricular tachycardia (VT) and multiple defibrillations following CRT-D implantation. Due to worsening cardiac function, the patient required surgical implantation of a left ventricular assist device (LVAD) as a bridge to heart transplantation. During the procedure, we used the Ensite three-dimensional mapping system to perform activation and substrate mapping of the VT targets, followed by endocardial and epicardial cryoballoon ablation of clinical VT.

Association between workplace violence from patients and the mental health status of healthcare workers in Zhuhai China: a cross-sectional study.

Objective: Workplace violence (WPV) poses a serious occupational risk. This study aims to explore the association between WPV from patients and the occurrence of insomnia, depression, and anxiety among healthcare workers.

Methods: Information about the WPV from patients was collected by a self-designed questionnaire.

Intracardiac Echocardiography and Ablation of Atrial Fibrillation in Dextrocardia.

Background: Dextrocardia with atrial fibrillation (AF) complicates radiofrequency ablation treatment.

Methods: A case of successful AF ablation in dextrocardia, guided by intracardiac echocardiography (ICE) and the Carto 3 high-density mapping system, is reported.

Results: ICE-guided transseptal puncture and three-dimensional mapping facilitated successful pulmonary vein isolation (PVI).

Atrial tachycardia originating from a right atrial free wall diverticulum: case report.

Background: Atrial tachycardia (AT) is an arrhythmic disorder originating from the atrium, independent of the atrioventricular node, and includes various types based on different mechanisms such as abnormal automaticity, triggered activity, and re-entry. These mechanisms are often related to specific anatomical structures. Focal AT, though relatively rare, typically arises from well-known locations in the left and right atria, such as the pulmonary veins, mitral valve annulus, crista terminalis, and coronary sinus ostium.

Alcohol imagery in popular films in China, 2001-2020.

This study aims to identify the level and trend of alcohol imagery in popular films in China from 2001 to 2020. We divided the running time of the annual 20 top-grossing films in China into 5-min intervals and coded those containing alcohol imagery, the presence of warnings, whether the imagery was related to minors and alcohol brands. Results showed that alcohol imagery occurred in 90.

Reproductive concerns and its correlation with fear of recurrence and level of family support in patients of childbearing age with gynecologic malignancies.

Background: To discuss the current status of reproductive concerns and its correlation with fear of recurrence and level of family support in patients of childbearing age with gynecologic malignancies.

Methods: A convenient sampling method was used to enroll 188 patients with gynecologic malignancies in Nanjing Maternity and Child Health Care Hospital, Nanjing Drum Tower Hospital, General Hospital of Ningxia Medical University, and Haian Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Chinese Medicine from September 2022 to April 2023. Patients were assessed using general information questionnaire, Reproductive Concerns After Cancer Scale (RCAC), Fear of Cancer Recurrence Inventory (FCRI) questionnaire, and Perceived Social Support-Family (PSS-FA) Scale.

When radiation meets the heart: Future of stereotactic body radiation therapy for hypertrophic obstructive cardiomyopathy.

Hypertrophic obstructive cardiomyopathy (HOCM) is a hereditary cardiac disorder characterized primarily by septal hypertrophy and left ventricular outflow tract obstruction. Traditional therapeutic modalities, such as medications and surgeries, do not yield satisfactory outcomes in a subset of patients. The advancements have been made in novel treatments, including new drugs and percutaneous intramyocardial septal radiofrequency ablation (PIMSRA), still need further observation to obtain long-term efficacy and safety.