Single Te Nanoribbon for Disrupting Conventional Sensitivity-Power Limits of Flexible Strain Sensors.

Flexible strain sensors are pivotal for the advancement of robotics, wearable healthcare, and human-machine interaction in the post-Moore era. However, conventional materials struggle to simultaneously achieve high sensitivity, a broad strain range, and low power consumption for cutting-edge applications. In this work, the issue is addressed through single crystal 1D tellurium nanoribbons (NRs), which are synthesized on SiO/Si substrate by hydrogen-assisted chemical vapor deposition (CVD) method.

Non-anticoagulant heparin alleviates myocardial ischemia-reperfusion injury through inhibiting GSDMD-mediated cardiomyocyte pyroptosis via the HMGB1/RAGE pathway.

Background: Heparin reduces myocardial ischemia-reperfusion (I/R) injury, which is associated with pyroptosis. As a derivative of heparin, non-anticoagulant heparin (NAH) is rarely researched in this field. This study aims to explore the mechanisms of NAH in myocardial I/R injury and pyroptosis.

Intrinsically Stretchable and Shape-Memory Phosphorescent Polymers by Atom Transfer Radical Polymerization.

Amorphous organic polymers with long-lived room-temperature phosphorescence (RTP) characteristics offer intriguing possibilities to advance information security, biological imaging, optoelectronic devices, and intelligent sensors. Despite the recent advances, access to phosphorescent polymers with excellent stretchability and shape memory performance remains a challenge. Herein, nanostructured RTP block copolymers biomimicking mussel cuticles were achieved by atom transfer radical polymerization (ATRP).

Obacunone ameliorates high-fat diet-induced MAFLD by regulating the PPARγ-FABP1/CD36 axis and the gut-liver crosstalk.

Background: Metabolic dysfunction-associated fatty liver disease (MAFLD) is a global health challenge with limited treatment options. Obacunone (Oba), a natural triterpenoid with anti-inflammatory and antioxidant properties, may address metabolic disorders, but its role in MAFLD is unclear.

Purpose: To investigate Oba's effects in high-fat diet (HFD)-induced MAFLD mice and free fatty acid (FFA)-stimulated HepG2 cells.

Association of the HDL lipidome with HDL traits before and after exercise training: HERITAGE family study.

Introduction: HDL particle functionality is influenced by its structure, including lipid composition. However, the effects of exercise training on the HDL lipidome and its relationship with HDL-related traits are largely unknown.

Objective: To investigate the HDL lipidome of 154 adults before and after 20 weeks of endurance exercise training in the HERITAGE Family Study.

Pulsed laser-assisted direct fabrication of MoWS alloy-based flexible strain sensors with superior performance for high-temperature applications.

Flexible strain sensors with high sensitivity and stability at high temperatures are significantly desirable for their accurate and long-term signal detection in wearable devices, environment monitoring, and aerospace electronics. Despite the considerable efforts in materials development and structural design, it remains a challenge to develop highly sensitive, flexible strain sensors operating at high temperatures due to the trade-off between sensitivity and stability for the representative sensing materials. Herein, we develop a high-temperature flexible sensor using MoWS alloy films.

[Research and clinical application progress of foot lengthening surgery].

Objective: To summarize the research and clinical application progress of foot lengthening surgery.

Methods: Relevant research literature on foot lengthening surgery in recent years at home and abroad was reviewed, and a summary was made from aspects such as the types of lengthening surgery, the types of foot diseases treated by clinical application, effectiveness, and complications.

Results: Bone defects and shortening deformities of the foot are relatively common clinically.

Supramalleolar osteotomy outcomes for post-traumatic fracture-related ankle arthritis: a retrospective analysis.

Background: This study aimed to investigate the early-to-mid-term efficacy of supramalleolar osteotomy (SMO) for the management of post-traumatic ankle arthritis resulting from previous fractures.

Methods: A retrospective analysis was conducted on the clinical data of 19 individuals with post-traumatic ankle arthritis secondary to old fractures treated with SMO between March 2018 and September 2022. The cohort included 6 males and 13 females, aged 15 to 59 years, with an average of 37.

Highly customizable, ultrawide-temperature free-form flexible sensing electronic systems based on medium-entropy alloy paintings.

High-performance flexible sensing electronics on complex surfaces operating across broad temperatures are critical for aerospace and industrial applications. However, existing flexible sensors and materials face limitations in sensitivity and thermal stability. Here, we report an ink-engineering strategy to directly print single-face MoWNb medium entropy alloy paints on arbitrary surfaces without complicated post-processing.

BiOIF Solid Solutions with Suitable Surface Halogen Vacancies for Comprehensive and Enhanced Photocatalytic Performance.

Bismuth oxyiodide (BiOI) is a highly promising material for photocatalytic degradation of pollutants, owing to its distinctive hierarchical and band structures. However, the poor photo-oxidation capability and fast recombination of photogenerated carriers constrain the application potential of BiOI. Introducing surface defects offers a compelling strategy for enhancing the photocatalytic performance.

A self-learning method with domain knowledge integration for intelligent welding sequence planning.

Due to the emergence of mass personalized production, intelligent welding systems must achieve high levels of productivity and flexibility. Therefore, a self-learning welding-task sequencing method that is driven by data and knowledge was developed during this study. First, a minimized dataset of welding sequences, which is required to predict the welding deformation, was designed according to the number and directions of the welds included in the welding tasks.

SRSF3 Inhibits High Glucose and Palmitic Acid-Induced Cardiomyocyte Apoptosis Through the PI3K/AKT and NF-κB Pathways.

Diabetic cardiomyopathy (DCM) has emerged as a leading cause of mortality among elderly patients with diabetes mellitus (DM). Currently, the pathogenic mechanisms underlying diabetic cardiomyopathy remain elusive. In the present study, we treated with H9C2 cells high glucose (Glu) and palmitic acid (PA) to establish an in vitro model, followed by proteomic profiling.

Fungal pathogen promotes caterpillar feeding and weight gain using a host-like trehalase.

Parasite-mediated extended phenotypes in hosts are of particular interest in biology. However, few parasite genes have been characterized for their selfish role in altering host behaviors to benefit parasite transmission or reproduction. The entomopathogenic fungus Cordyceps militaris infects caterpillar larvae without killing them until after pupation.

Femtosecond Laser-Induced Nanostructured Sacrificial Layer for Stable Zinc Metal Anode.

Aqueous zinc-ion batteries are a promising option for grid-scale energy storage owing to their cost-effectiveness and safety. The Zn metal anode with large gravimetric capacity and moderate redox potential can enable high-energy-density Zn batteries. However, the surface instability of commercial Zn metal foils leads to capacity degradation and limited cycle life of batteries.

First-principles investigations of electronic property modulation in the FeCl/MoSiN heterojunction by strain, interlayer distance and vertical electric field variation.

This study investigated the changes in the electronic properties of the FeCl/MoSiN heterostructure by modulating interlayer distance, in-plane strain, and external electric field. The results indicated that the FeCl/MoSiN van der Waals heterostructure (vdWH) is an indirect band gap semiconductor with a band gap of 1.21/2.

Early Detection of Hydrogen Leakage Using Fiber Optic Hydrogen Sensor Based on WO-PdPt-Pt Nanocomposite Films.

Quickly detecting hydrogen leakage is crucial to provide early warning for taking emergency measures to avoid personnel casualties and explosion accidents in hydrogen energy fields. Here, a compact optical fiber hydrogen sensing system with high sensitivity and quick response rate is proposed in this work. A laser diode (LD) and two photodetectors (PD) are employed as light source and optical signal transformation devices, respectively.

S1PR2 Mediates Smooth Muscle Cell Proliferation and Endothelial Cell Permeability via Akt/mTOR and RhoA/ROCK1 in Atherosclerosis.

Atherosclerosis is a complex disease involving a series of interrelated events, among which endothelial cell dysfunction and vascular smooth muscle cell proliferation play pivotal roles in the early formation of atherosclerotic plaques. Sphingosine 1-phosphate, a product of sphingomyelin metabolism, serves as a signaling molecule implicated in the pathogenesis of atherosclerosis and other conditions by binding to sphingosine 1-phosphate receptors (S1PRs). However, the precise mechanism by which S1PRs influence atherosclerosis remains incompletely understood.

Reconfigurable Artificial Synapses Based on Ambipolar Environmentally Stable Tellurium for Neuromorphic Computing.

Neuromorphic computing, a promising solution to the von Neumann bottleneck, is paving the way for next-generation computing and sensing systems. However, most studies of artificial synapses mimic only static plasticity, which is far from achieving the complex behaviors of the human brain. Here, we report a reliable neuromorphic computing system that integrates a top floating gate memory architecture and uses peculiar ambipolar tellurium (Te) as a channel material to fabricate reliable nonvolatile memory cells.

[Source Apportionment of Soil Heavy Metals in Moqi Area on the Northwest Edge of Songnen Plain Based on the PCA-PMF Model].

Black soil resources are widely distributed in Morin Dawa Daur Autonomous Banner （Moqi）, northwest margin of the Songnen Plain, which is an advanced county of grain production in China and an important agricultural producing area in the east of Hulunbuir City, Inner Mongolia. Carrying out research on distribution characteristics and source apportionment of heavy metals in soil is important for preventing and controlling ecological environmental risks and protecting black soil in the northwest margin of the Songnen Plain. A total of 161 surface soil sites were systematically collected from black soil in the Moqi area, and the contents and spatial distribution characteristics of eight heavy metals （Cu, Pb, Ni, Cd, Cr, Zn, As, and Hg） were analyzed.

Clinical Characteristics and Outcomes of Catheter Ablation in Young Patients With Atrial Fibrillation.

Background: Data concerning young patients with atrial fibrillation (AF) are currently limited.

Hypothesis: This study aimed to assess the clinical characteristics and risk factors for AF recurrence in young patients following catheter ablation (CA).

Methods: All AF patients aged ≤ 45 years who underwent CA were identified from the China Atrial Fibrillation Center database between September 2018 and September 2023.

Stretchable multifunctional wearable system for real-time and on-demand thermotherapy of arthritis.

Thermotherapy is a conventional and effective physiotherapy for arthritis. However, the current thermotherapy devices are often bulky and lack real-time temperature feedback and self-adjustment functions. Here, we developed a multifunctional wearable system for real-time thermotherapy of arthritic joints based on a multilayered flexible electronic device consisting of homomorphic hollow thin-film sensors and heater.

A cytokine receptor domeless restrains mud crab reovirus infection via JAK-STAT signaling pathway in mud crab (Scylla paramamosain).

JAK/STAT signaling pathways are associated with the innate immune system and play important roles in mediating immune responses to virus infection. Domeless is a unique receptor involved in invertebrate JAK/STAT pathway. In this study, a Domeless gene from Scylla paramamosain, named SpDOME, was cloned and characterized.

Linear Annulation Engineering of Indolocarbazole Multiple Resonance Emitter to Overcome Efficiency-Stability-Color Purity Trilemma in Deep-Blue OLEDs.

Deep-blue emitters for organic light-emitting diodes (OLEDs) still confront the critical challenge of balancing high efficiency, operational stability, and color purity, particularly for the ones with peak wavelengths (λ) ≤ 460 nm. Here, the study demonstrates deep-blue devices featuring ultrapure emission (λ = 458 nm, full-width at half-maximum = 19 nm), high maximum external quantum efficiency of 34.3% with small roll-off (26.

Sleep architecture and quality and pain experience in individuals with persistent low back pain and asymptomatic controls.

Introduction: Both pain and sleep have a broad impact on health and well-being. There is a bi-directional association between pain and sleep, but how sleep and pain are associated chronically remains unclear. This study examined the associations of sleep architecture and quality in relation to pain experience and its impact in individuals with persistent low back pain (pLBP) and asymptomatic controls.