Factors Influencing an Early Career Choice of Child and Adolescent Psychiatry Among Chinese Medical Students: An Exploratory Survey.

Objective: The study aimed to explore factors influencing Chinese medical students' career choices, especially in choosing child and adolescent psychiatry (CAP) as their specialty.

Method: A 23-item online survey was conducted among third-year medical students at Peking University Health Science Center to explore the factors currently influencing their career choices, as well as their preferences and factors that influence the choice of CAP as a career specialty. Their preferences for CAP-focused curricula were also surveyed.

Strategic implementation of child and adolescent psychiatry training in Chinese residency programs: an exploratory survey.

Background: The workforce shortage in child and adolescent psychiatry (CAP) in China greatly restricts patients' access to child and adolescent mental health services (CAMHS). Implementing CAP training within general or adult psychiatry programs may offer a viable solution; however, such programs are underdeveloped in China. The aim of this study was to gather empirical evidence regarding CAP training needs within Chinese psychiatry residency programs.

Manipulating perovskite structural asymmetry for high-performing self-powered full-stokes polarimetry.

Developing direct full-stokes imaging polarimetry is essential for various applications but remains challenging. Perovskites have superior optoelectronic properties and structural diversity, making them ideal candidates for high-performing direct full-stokes polarimetry. However, perovskite suffers low chiroptical activity due to inefficient chiral transfer, which greatly limits its circular-polarization-vector discrimination.

Managing Edge States in Reduced-Dimensional Perovskites for Highly Efficient Deep-Blue LEDs.

Pure-halide reduced-dimensional perovskites, featuring large exciton binding energy and tunable bandgap, show great potential for high-efficiency deep-blue perovskite light-emitting diodes (PeLEDs). However, their efficiency, particularly in the low n-value phase domain ("n" represents the number of octahedral sheets), lags behind analogous perovskite emitters. Herein, it is demonstrated that the vibration of edge-dangling octahedra in the low n-value phase activates notorious exciton-phonon (EP) coupling, thereby deteriorating efficiency.

Efficacy of a self-made tracheostomy oxygen delivery device for oxygen therapy during postoperative anesthesia recovery.

Background: Patients with tracheotomy are often monitored in the anesthesia recovery room after reoperation. During this period, oxygen therapy is necessary, and the existing tracheostomy oxygen supply device has many defects.

Objective: To evaluate the efficacy of a self-made tracheostomy oxygen delivery device on oxygen therapy during postoperative anesthesia recovery.

Iron deficiency at birth and risk of hidden hearing loss in infants modification by socioeconomic status: mother-newborn cohort in Shenyang, China.

Objective: The diagnosis of hidden hearing loss (HHL) in calm state has not yet been determined, while the nutritional status is not involved in its pathogenic risk factors. In utero iron deficiency (ID) may delay auditory neural maturation in infants. We evaluated the association between ID and HHL as well as the modification effect of socioeconomic status (SES) on this association in newborns.

Directly seeding epitaxial growth of tungsten oxides/tungsten diselenide mixed-dimensional heterostructures with excellent optical properties.

Mixed-dimensional heterostructures have drawn significant attention due to their intriguing physical properties and potential applications in electronic and optoelectronic nanodevices. However, limited by the lattice matching, the preparation of heterostructures is experimentally difficult and the underlying growth mechanism has not been well established. Here, we report a three-step seeding epitaxial growth strategy for synthesizing mixed-dimensional heterostructures of one-dimensional microwire (MW) and two-dimensional atomic thin film.

Astragalus polysaccharide ameliorates insulin resistance in HepG2 cells through activating the STAT5/IGF-1 pathway.

Background: Insulin resistance (IR) is considered as a major factor initiating type 2 diabetes mellitus and can lead to a reduction in glucose uptake that mainly occurs in the liver. Astragalus polysaccharide (APC), extracted from the traditional Chinese medicine, has been recorded to suppress IR. However, the underlying mechanism remains inadequately explored.

The Clinical Manifestation, Executive Dysfunction, and Caregiver Strain in Subthreshold Attention-Deficit/Hyperactivity Disorder.

Objective: Subthreshold attention-deficit/hyperactivity disorder (ADHD) has been suggested to be a "morbid condition" which also needs medical attention.

Methods: The present study recruited 89 children with subthreshold ADHD (sADHD), 115 children with diagnosed ADHD (cADHD), and 79 healthy controls (HC) to explore the clinical manifestation, executive functions (EFs) of sADHD, and the caregiver strain. The clinical manifestation was evaluated through clinical interviews and parent-reports.

Prediction and Global Sensitivity Analysis of Long-Term Deflections in Reinforced Concrete Flexural Structures Using Surrogate Models.

Reinforced concrete (RC) is the result of a combination of steel reinforcing rods (which have high tensile) and concrete (which has high compressive strength). Additionally, the prediction of long-term deformations of RC flexural structures and the magnitude of the influence of the relevant material and geometric parameters are important for evaluating their serviceability and safety throughout their life cycles. Empirical methods for predicting the long-term deformation of RC structures are limited due to the difficulty of considering all the influencing factors.

A completely digital workflow aided by cone beam computed tomography scanning to maintain jaw relationships for implant-supported fixed complete dentures: A clinical study.

Statement Of Problem: The conventional workflow for the fabrication of implant-supported fixed complete dentures (IFCDs) is complex and makes it impossible to maintain jaw relationships. A fully digital workflow might solve this problem.

Purpose: The purpose of this clinical study was to develop a completely digital workflow aided by a cone beam computed tomography (CBCT) scan for the fabrication of IFCDs and to evaluate the accuracy of this workflow with regard to the maintenance of jaw relationships.

Designing a multi-epitope vaccine against coxsackievirus B based on immunoinformatics approaches.

Coxsackievirus B (CVB) is one of the major viral pathogens of human myocarditis and cardiomyopathy without any effective preventive measures; therefore, it is necessary to develop a safe and efficacious vaccine against CVB. Immunoinformatics methods are both economical and convenient as simulations can shorten the development time. Herein, we design a novel multi-epitope vaccine for the prevention of CVB by using immunoinformatics methods.

Effect of comprehensive nursing intervention for congenital heart disease in children: A meta-analysis.

Objectives: This meta-analysis aimed to assess the impact of nursing interventions (e.g., educational and empathic interviewing, motor exercise, therapeutic play interventions) on the perioperative outcome of children with congenital heart disease (CHD).

Circular RNA circ_0076631 promotes coxsackievirus B3 infection through modulating viral translation by sponging miR-214-3p.

Coxsackievirus B (CVB), a member of genus of , is the leading pathogen of viral myocarditis and dilated cardiomyopathy. The pathogenesis of CVB-induced myocarditis has not been completely elucidated, and no specific antiviral measurement is available presently. Circular RNAs (circRNAs) have been reported to be able to modulate viral replication and infection through bridging over non-coding RNAs (ncRNAs) and coding messenger RNAs (mRNAs).

Accuracy of 2 direct digital scanning techniques-intraoral scanning and stereophotogrammetry-for complete arch implant-supported fixed prostheses: A prospective study.

Statement Of Problem: Conventional impression techniques for complete arch implant-supported prostheses are technique-sensitive. Stereophotogrammetry (SPG) and intraoral scanning (IOS) may offer an alternative to conventional impression making.

Purpose: The purpose of this prospective study was to compare the accuracy of IOS and SPG for complete arch implant scans and to evaluate the passive fit of frameworks fabricated with SPG.

Affective-cognitive-behavioral heterogeneity of Attention-Deficit/Hyperactivity Disorder (ADHD): Emotional dysregulation as a sentinel symptom differentiating "ADHD-simplex" and "ADHD-complex" syndromes?

Background: Current DSM and ICD classifications of Attention-Deficit/Hyperactivity Disorder (ADHD) exclude emotional dysregulation (ED) in their diagnostic criteria, despite ED symptoms frequently co-occurring in ADHD and likely sharing common neurobiological substrates. In this study, we examined whether consideration of ED symptoms could delineate more informative "ADHD+ED" subphenotypes.

Method: 4106 children with ADHD were recruited.

Accuracy of photogrammetry, intraoral scanning, and conventional impression techniques for complete-arch implant rehabilitation: an in vitro comparative study.

Background: To compare the accuracy of photogrammetry, intraoral scanning and conventional impression techniques for complete-arch implant rehabilitation.

Methods: A master cast containing 6 implant abutment replicas was fabricated. Group PG: digital impressions were taken 10 times using a photogrammetry system; Group IOS: intraoral scanning was performed to fabricate 10 digital impressions; Group CNV: splinted open-tray impression technique was used to fabricate 10 definitive casts.

Co-Delivery of Curcumin and Capsaicin by Dual-Targeting Liposomes for Inhibition of aHSC-Induced Drug Resistance and Metastasis.

Recent research studies have shown that the low survival rate of liver cancer is due to drug resistance and metastasis. In the tumor microenvironment (TME), activated hepatic stellate cells (aHSCs) have been proven to favor the development of liver cancer. Hence, the combination therapy dual-targeting aHSCs and tumor cells might be an effective strategy for treatment of liver cancer.

Marginal Bone Loss around Machined Smooth Neck Implants Compared to Rough Threaded Neck Implants: A Systematic Review and Meta-Analysis.

Purpose: The purpose of this meta-analysis was to assess the effect of rough threaded neck implants on marginal bone loss, compared to machined smooth neck implants.

Materials And Methods: Literature searches were performed in the Cochrane Central Register of Controlled Trials (The Cochrane Library) (up to March 04, 2020), MEDLINE (PubMed) (1966 to March 04, 2020), and EMBASE (1980 to March 04, 2020), and reference lists of relevant manuscripts and relevant systematic reviews. Grey literature was sought using Grey Literature Net-Work Service (www.

SHP2 knockdown ameliorates liver insulin resistance by activating IRS-2 phosphorylation through the AKT and ERK1/2 signaling pathways.

Diabetes is a chronic metabolic disease characterized by insulin resistance (IR). SHP2 has previously been identified as a potential target to reduce IR in diabetes. Here, we examined the effects of SHP2 on glucose consumption (GC), IR level and the expression of insulin receptor substrate (IRS), AKT and extracellular signal-regulated kinase (ERK)1/2 proteins in a cellular and animal model of diabetes.

Classifying major depression patients and healthy controls using EEG, eye tracking and galvanic skin response data.

Objective: Major depression disorder (MDD) is one of the most prevalent mental disorders worldwide. Diagnosing depression in the early stage is crucial to treatment process. However, due to depression's comorbid nature and the subjectivity in diagnosis, an early diagnosis could be challenging.

Preparation of Efficient BiOBr/MIL-88B(Fe) Composites with Enhanced Photocatalytic Activities.

  In this study, a novel composite containing an iron based metal-organic framework (MOF) and BiOBr was successfully synthesized by a simple method, and was fully characterized by X-ray diffraction patterns, Fourier transform infrared spectra, UV-vis diffuse reflectance spectra, and transmission electron microscopy. Moreover, the photocatalytic activities of BiOBr/MIL-88B(Fe) composites and the pure materials were evaluated by measuring the degradation of Rhodamine B under visible light. The results show that the composite exhibits better photocatalytic activities than pure materials, which can be ascribed to the high adsorption capacity of MIL-88B(Fe) and the enhanced separation of photogenerated charge carriers from assembly of MIL-88B(Fe) on BiOBr.

Core-shell Fe3O4@MIL-101(Fe) composites as heterogeneous catalysts of persulfate activation for the removal of Acid Orange 7.

In this study, a novel core-shell Fe3O4@MIL-101 (MIL stands for Materials of Institute Lavoisier) composite was successfully synthesized by hydrothermal method and was fully characterized by X-ray diffraction, transmission electron microscopy, Fourier-transform infrared spectra, and X-ray photoelectron spectroscopy. The composite was introduced as a catalyst to generate powerful radicals from persulfate for the removal of Acid Orange 7 in an aqueous solution. Effects of the central metal ions of MIL-101, amino group content of MIL-101, and pH were evaluated in batch experiments.

In vivo evaluation of a simvastatin-loaded nanostructured lipid carrier for bone tissue regeneration.

Alveolar bone loss has long been a challenge in clinical dental implant therapy. Simvastatin (SV) has been demonstrated to exert excellent anabolic effects on bone. However, the successful use of SV to increase bone formation in vivo largely depends on the local concentration of SV at the site of action, and there have been continuing efforts to develop an appropriate delivery system.

Degradation of Acid Orange 7 in aqueous solution by dioxygen activation in a pyrite/H₂O/O₂ system.

Increasing attention has been paid to pyrite due to its ability to generate hydroxyl radicals in air-saturated solutions. In this study, the mineral pyrite was studied as a catalyst to activate molecular oxygen to degrade Acid Orange 7 (AO7) in aqueous solution. A complete set of control experiments were conducted to optimize the reaction conditions, including the dosage of pyrite, the AO7 concentration, as well as the initial pH value.