Unveiling the diagnostic power of lncRNAs in colorectal cancer: a meta-analysis.

Background: Colorectal cancer (CRC) is a highly aggressive and extensive malignancy. Although long noncoding RNAs (lncRNAs) are often used as diagnostic biomarkers, their diagnostic effectiveness in CRC remains uncertain.

Methods: From January 1, 2015, to April 1, 2024, we conducted a comprehensive search of Embase, China National Knowledge Infrastructure (CNKI), Wanfang, PubMed, Cochrane Library, and Web of Science (WoS).

Manual Delineation of the Region of Interest Combined With Clinical Image Analysis to Predict the Ki-67 Expression Level in Non-small Cell Lung Cancer.

Background: The Ki-67 antigen, a marker of cell proliferation, serves as a biomarker for assessing tumor malignancy. However, measuring Ki-67 levels through immunohistochemistry is often challenging due to difficulties in specimen collection and individual health issues. Radiological analysis has emerged as a potential alternative for predicting Ki-67 levels, although its accuracy has been limited.

Comparative Analysis of Long-Term Outcomes Between Near-Infrared Fluorescence Imaging with Indocyanine Green-Guided Mediastinal Lymphadenectomy and Conventional Surgery for Esophageal Cancer.

Background: This study aimed to compare the long-term oncologic outcomes of NIRF-guided mediastinal lymphadenectomy during esophagectomy with those of conventional surgery.

Methods: The study enrolled consecutive patients who underwent esophagectomy for esophageal cancer by a single surgical team between September 2017 and July 2021. Patients treated after September 2019 received NIRF-guided mediastinal lymphadenectomy (NIRF group) and were compared with the earlier cohort (historical control group).

Three new species from the Middle Jurassic of China provide insights on wing spots diversity of Bittacidae (Insecta: Mecoptera).

Three new species, Antiquanabittacus punctatus Yu, Ren, Lin and Yang sp. nov., Composibittacus retroflexus Yu, Ren, Lin and Yang sp.

Spread Spectrum Image Watermarking Through Latent Diffusion Model.

The rapid development of diffusion models in image generation and processing has led to significant security concerns. Diffusion models are capable of producing highly realistic images that are indistinguishable from real ones. Although deploying a watermarking system can be a countermeasure to verify the ownership or the origin of images, the regeneration attacks arising from diffusion models can easily remove the embedded watermark from the images, without compromising their perceptual quality.

Analysis of the Correlation between Frailty Index, Clinical Characteristics, Use of Anti-Epileptic Drug, and Prognosis in Elderly Patients with Epilepsy.

Background: Epilepsy is a common neurological disorder among the elderly, often leading to significant morbidity. Therefore, it is necessary to study the correlation between the frailty index, clinical characteristics of epilepsy, use of anti-epileptic drug, and the prognosis of elderly patients with epilepsy.

Methods: This retrospective study included 106 elderly patients with epilepsy who were treated at the Affiliated Mindong Hospital, Fujian Medical University, China, between January 2018 and December 2022.

Improved CNN Prediction Based Reversible Data Hiding for Images.

This paper proposes a reversible data hiding (RDH) scheme for images with an improved convolutional neural network (CNN) predictor (ICNNP) that consists of three modules for feature extraction, pixel prediction, and complexity prediction, respectively. Due to predicting the complexity of each pixel with the ICNNP during the embedding process, the proposed scheme can achieve superior performance compared to a CNNP-based scheme. Specifically, an input image is first split into two sub-images, i.

Ocular hypertension after silicone oil filling surgery for high myopia: a case-control study.

Purpose: This study aims to examine the correlation between specific clinical parameters, such as axial eye length, and the onset of ocular hypertension "OH" following the use of silicone oil filling in patients with high myopia.

Method: In this retrospective analysis, we reviewed 214 eyes from 432 patients diagnosed with severe myopia, all of whom underwent vitrectomy and were treated with silicone oil filling. The study aimed to document the incidence and timing of postoperative ocular hypertension "OH" while assessing various factors, including demographic details, medical history, additional surgical interventions, and findings from supplementary examinations (such as axial length, silicone oil emulsification, and anterior chamber penetration).

Age at onset mediates genetic impact on disease severity in facioscapulohumeral muscular dystrophy.

Facioscapulohumeral muscular dystrophy type 1 (FSHD1) patients exhibit marked variability in both age at onset (AAO) and disease severity. Early onset FSHD1 patients are at an increased risk of severe weakness, and early onset has been tentatively linked to the length of D4Z4 repeat units (RUs) and methylation levels. The present study explored potential relationships among genetic characteristics, AAO and disease severity in FSHD1.

Research and design of multiple gas mixing system in modified atmosphere packaging.

Despite the abundant production of fruits and vegetables in Xinjiang, there is an increasing trend in waste rates. Gas-controlled packaging techniques are employed post-harvest to enhance freshness and extend shelf life. However, the multi-gas mixing system at the core of this equipment often encounters challenges such as insufficient stability, limited precision, high costs, and inadequate intelligence.

Effect of cervical pillow in phacoemulsification surgery for age-related cataract patients: a prospective randomized controlled study.

Purpose: To explore the application effect of cervical pillow in phacoemulsification surgery for age-related cataract patients.

Methods: 104 cases of age-related cataract patients admitted to our hospital in June 2023 were enrolled and divided into the control group (traditional supine position) and the experimental group (the cervical pillow supine position) by the digital parity method (52 cases per group). The two groups were evaluated for the discomfort score, the satisfaction of patients and doctors, the head displacement rate, the number of displacement, the operation time and the time of body position during the operation and after the operation.

Laparoscopic liver resection is superior to radiofrequency ablation for small hepatocellular carcinoma: a systematic review and meta-analysis of propensity score-matched studies.

Background: The approach in small hepatocellular carcinoma (HCC) is controversial, no prospective randomized trials to compare ablative or surgical approaches. We compared the surgical and oncological outcomes after laparoscopic hepatectomy (LH) and radiofrequency ablation (RFA) in small HCC patients based on matched cohort studies that performed propensity score matching (PSM).

Methods: We systemically searched the PubMed, Cochrane Library, Embase, Web of Science, and the Chinese BioMedical Literature (CBM) databases.

Association between C677T polymorphism and cognitive impairment in patients with cerebral small vessel disease: a cross-sectional study.

Objective: Cerebral small vessel disease (CSVD) is the most common vascular cause of cognitive impairment. This study aimed to explore the association between C677T polymorphism and cognitive impairment in CSVD patients.

Methods: Demographic, medical, laboratory, cognitive evaluation, and C677T polymorphism data were collected from CSVD patients admitted to our hospital between January 2019 and July 2023.

Existential distress and associated factors in advanced cancer patients: A cross-sectional study.

Background: Advanced cancer patients often experience existential distress (ED). However, the factors associated with ED remain unclear. This study investigated the current state of ED and identified the associated factors in Chinese patients with advanced cancer.

Insights into the Superrosids phylogeny and flavonoid synthesis from the telomere-to-telomere gap-free genome assembly of Pursh.

The completion of the first telomere-to-telomere (T2T) genome assembly of Pursh (PC), a prominent medicinal plant in China, represents a significant achievement. This assembly spans a length of 257.5 Mb and consists of nine chromosomes.

Comparison of Postoperative Outcomes Between Near-Infrared Fluorescent Imaging-Guided Mediastinal Lymphadenectomy and Conventional Surgery for Esophageal Cancer.

Background: The study aimed to evaluate the efficacy of using near-infrared fluorescent imaging (NIRF) imaging with indocyanine green as an intraoperative tool for achieving complete mediastinal lymph node (LN) resection.

Patients And Methods: Between September 2019 and July 2021, patients with potential for esophagectomy due to middle and lower thoracic esophageal cancer were enrolled in this study. All patients were scheduled for NIRF-guided mediastinal lymphadenectomy during esophageal cancer surgery and were appropriately assigned to the NIRF group.

Concurrent chemoradiotherapy versus radiotherapy alone in older patients with stage II nasopharyngeal carcinoma after intensity-modulated radiotherapy: A propensity score-matched cohort study.

Background And Purpose: Whether concurrent chemoradiotherapy (CCRT) benefits the older (age ≥ 60 years) patients with stage II nasopharyngeal carcinoma (NPC) has not been determined. This study aimed to compare the outcomes and toxicities of CCRT with Intensity-Modulated Radiotherapy (IMRT) alone in older patients with stage II NPC.

Materials And Methods: Between January 2010 and December 2017, 220 older (age ≥ 60 years) patients with stage II NPC were analyzed.

A new method for examining the co-occurrence network of fossil assemblages.

Currently, studies of ancient faunal community networks have been based mostly on uniformitarian and functional morphological evidence. As an important source of data, taphonomic evidence offers the opportunity to provide a broader scope for understanding palaeoecology. However, palaeoecological research methods based on taphonomic evidence are relatively rare, especially for body fossils in lacustrine sediments.

The effect of body mass index on quality of life in modified single stoma cutaneous ureterostomy or ileal conduit after radical cystectomy.

Objective: To explore the influence of postoperative body mass index (BMI) change on postoperative quality of life (QOL) in patients undergoing radical cystectomy (RC) plus modified single stoma cutaneous ureterostomy (MSSCU) or ileal conduit (IC).

Methods: Patients were divided into two groups according to different BMI change patterns: patients experiencing an elevated postoperative BMI level, along with a clinically significant increase in their BMI (an increase of more than 10%) were categorized as Group 1, while patients experiencing a decrease postoperative BMI level, along with a clinically significant reduction in their BMI (a decrease of more than 5%) were categorized as Group 2. Spearman correlation analysis was used to examine the correlations between quality-of-life scores and postoperative clinical parameters.