Effects of Scalable, Wordless, Short, Animated Storytelling Videos on Flu Vaccine Hesitancy in China: Nationwide, Single-Blind, Parallel-Group, Randomized Controlled Trial.

Background: Low influenza vaccination rates in China pose a serious public health threat. The vaccination prevents infection, but widespread vaccine hesitancy remains a significant barrier. Short, animated storytelling videos may help by conveying health messages in an engaging, culturally neutral format that transcends literacy barriers.

Faster, safer, better recovery: a modified robotic-assisted segmentectomy versus conventional approaches in early stage lung cancer.

The aim of this study is to evaluate the perioperative results of patients who receive robot-assisted thoracoscopic (RATS) modified segmentectomy and to compare the effectiveness and safety of this approach with those of traditional segmentectomy methods. A retrospective analysis was conducted on perioperative data from 587 consecutive patients diagnosed with early stage lung cancer who underwent robot-assisted thoracoscopic segmentectomy between January 2020 and September 2024. Using a 1:1 propensity score matching approach, 326 patients were paired based on clinical variables, such as age, sex, body weight, height, pulmonary function test results, and tumor size as measured by CT.

CircPhc3 promotes the repair of intestinal mucosa after burn injury through the TRIM28-mediated hnRNPK SUMOylation stability modification mechanism.

This paper investigates the mechanism of action of circPhc3 in the repair of intestinal mucosa in mice with severe burn injuries. The expression of circPhc3 is decreased in the intestinal mucosal tissue of these mice, and its overexpression may aid in the reconstruction of the damaged mucosa. The effects of circPhc3 on cell proliferation and migration were studied in MC38 cells, with an initial assessment of its repair function in mouse intestinal mucosa.

The global burden of disease attributable to suboptimal fruit and vegetable intake, 1990-2021: a systematic analysis of the global burden of disease study.

Background: Suboptimal fruit and vegetable intake remains a significant global public health concern. This study aimed to estimate the global intake and the disease burden attributable to suboptimal fruit and vegetable intake.

Methods: In this Global Burden of Disease (GBD) Study 2021, we evaluated the number, age-standardized rates (ASRs), and estimated annual percentage changes (EAPCs) in deaths and disability-adjusted life years (DALYs) attributable to suboptimal fruit and vegetable intake among adults aged over 25 years, across 21 regions and 204 countries and territories, from 1990 to 2021.

Burden of chronic respiratory diseases and their attributable risk factors in 204 countries and territories, 1990-2021: Results from the global burden of disease study 2021.

Background: Chronic respiratory diseases (CRDs) remain a substantial global public health challenge, contributing significantly to morbidity and mortality worldwide. This study aimed to comprehensively characterize trends in CRD burden across various populations by examining differences by sex, age, and sociodemographic index (SDI).

Methods: We performed a systematic analysis using data from the Global Burden of Disease (GBD) 2021 study, covering the period from 1990 to 2021 across 204 countries and territories.

Effects of generative artificial intelligence on cognitive effort and task performance: study protocol for a randomized controlled experiment among college students.

Background: The advancement of generative artificial intelligence (AI) has shown great potential to enhance productivity in many cognitive tasks. However, concerns are raised that the use of generative AI may erode human cognition due to over-reliance. Conversely, others argue that generative AI holds the promise to augment human cognition by automating menial tasks and offering insights that extend one's cognitive abilities.

Effects of scalable, wordless, short, animated storytelling videos on hope in China: a nationwide, single-blind, parallel-group, randomised controlled trial.

Background: People with higher levels of hope are more likely to be vaccinated. Short, animated story (SAS) videos have shown promise for communicating health messages and boosting hope in certain populations. We explored the potential of scalable SAS vaccine promotion videos for boosting hope levels among Chinese adults.

Effects of Dietary Net Energy/Lysine Ratio and Sex on Growth Performance, Digestive Organ Development, and Cecal Microbiota of Broiler Chickens.

This study aimed to investigate the effects of the net energy (NE) and lysine ratio in low-protein diets on growth performance, intestinal development, and cecal microbiota of male and female broilers. A 4 × 2 factorial design was used with lysine levels at 1% and 1.5%, and net energy levels at 8.

Optimizing hypertension management in China: care cascade insights and individual determinants from a national survey.

Objectives: Hypertension is common in China, and its prevalence has been increasing. However, it remains inadequately controlled. This study examined patterns of patient attrition across the stages of hypertension management in the general population and their variations across subpopulations, and assessed the role of individual-level determinants of hypertension management.

Intestinal inflammation disrupts energy metabolism in layer pullets: insights into energy partitioning and intestinal metabolomic profiling.

Background: Intestinal inflammation is an energy-consuming process that may alter energy supply and demand in poultry. During inflammation, the intestinal energy metabolic profile and the patterns of energy partitioning remain unclear. This study investigated the effects of intestinal inflammation on energy intake, heat production (HP), retained energy (RE) and intestinal energy metabolites in layer pullets.

Regional mobility and COVID-19 vaccine hesitancy: Evidence from China.

China's Zero-COVID Policy imposed stringent restrictions on citizens' mobility to curb the spread of COVID-19. While effective in reducing viral transmission, these measures may have inadvertently delayed or deterred vaccine uptake by fostering a heightened sense of security. This study examines the relationships between intra- and inter-regional travel mobility and individual hesitancy towards COVID-19 vaccines (HCV), leveraging the Baidu Mobility Index and data from a cross-sectional survey of 12,000 participants.

Estimated glucose processing rates and the association of chronic kidney disease and proteinuria in non-diabetic adults.

The study, which was based on NHANES data (1999-2018), included 21,234 nondiabetic individuals aged 20 years and older to investigate the associations between the estimated glucose disposal rate (eGDR) and the risk of chronic kidney disease (CKD) and proteinuria. CKD was defined as an estimated glomerular filtration rate (eGFR) less than 60 mL/min/1.73 m, and proteinuria was defined as a urinary albumin-to-creatinine ratio (UACR) exceeding 30 mg/g.

Estimates and projections in the economic impacts of fifteen dietary risk factors for two hundred four countries and territories from 2020 to 2050: A health-augmented macroeconomic modeling study.

Background: Suboptimal diet results in significant health and economic burdens. However, the global economic costs of dietary risks remain unclear.

Objectives: This study aimed to estimate the macroeconomic burden of 15 dietary risk factors in 204 countries and territories from 2020 to 2050.

Corrigendum to "Epidemiology of pulmonary embolism in China, 2021: a nationwide hospital-based study", [The Lancet Regional Health - Western Pacific, Volume 54, January 2025, 101258].

[This corrects the article DOI: 10.1016/j.lanwpc.

Disulfiram-Loaded PLGA nanoparticles modified with a Phenyl borate chitosan Conjugate enhance hepatic carcinoma treatment.

Disulfiram (DSF), which has been traditionally used to treat alcoholism, has been shown to inhibit tumor growth, indicating its potential as an anticancer agent. However, its development and application are hindered by its poor water solubility, instability in physiological environments, and low bioavailability. In this study, phenylboronic acid-chitosan (PBA-CS) grafts were synthesized using the carbodiimide method.

Sparse loudspeaker array design for wideband frequency-invariant beamforming with multiple targets.

Beamforming technology using loudspeaker arrays is widely used in sound applications, but current sparse array design methods focus on optimizing a single beam for a single target direction, limiting their applicability to multi-channel sound systems. This paper presents a design method for sparse loudspeaker line arrays to generate wideband frequency-invariant beams in multiple target directions. A model based on tapped delay lines is developed and a two-stage design approach is proposed.

Epidemiology of pulmonary embolism in China, 2021: a nationwide hospital-based study.

Background: Pulmonary embolism (PE) as a preventable and potentially fatal noncommunicable disease was believed to have a lower incidence in Asian populations compared to Western populations. However, the incidence and mortality rates of PE in China and the impact of venous thromboembolism (VTE) prevention system constructions on PE still lack nationwide evidence.

Methods: For this nationwide hospital-based observational study, we used data from the National Hospital Quality Monitoring System (HQMS) and public database in China.

Functional dependency and cardiometabolic multimorbidity in older people: pooled analysis of individual-level data from 20 countries.

Background: The impact of cardiometabolic multimorbidity (CMM) on functional dependency (FD) is well established, but the temporal effect of FD on CMM and its mechanisms remain underexplored.

Design: A multicohort study pooled data from three international cohorts.

Setting: Data were sourced from the Health and Retirement Study (USA), the China Health and Retirement Longitudinal Study (China) and the Survey of Health, Ageing and Retirement in 18 European countries.

Neutrophil-based single-cell sequencing combined with transcriptome sequencing to explore a prognostic model of sepsis.

Sepsis is a life-threatening condition influenced by various factors. Although gene expression profiling has offered new insights, accurately assessing patient risk and prognosis remains challenging. We utilized single-cell and gene expression data of sepsis patients from public databases.

Effects of comprehensive smoke-free legislation on smoking behaviours and macroeconomic outcomes in Shanghai, China: a difference-in-differences analysis and modelling study.

Background: China has one of the highest levels of tobacco consumption globally, and there is no national smoke-free legislation. Although more than 20 Chinese cities have passed local smoke-free laws since 2008, evidence on their effectiveness in reducing smoking behaviours and their economic benefits is scarce. By exploiting a natural quasi-experiment, whereby a comprehensive public smoking ban was implemented in Shanghai in March, 2017, this study aims to assess the impact of the policy on individual smoking behaviours and quantify its effect on macroeconomic outcomes.

HPV vaccination is highly effective and cost-effective for cervical cancer prevention in women living with HIV in China: A cost-effectiveness analysis.

The presence of human immunodeficiency virus (HIV) infection increases the risk of acquiring human papillomavirus (HPV) infection and developing HPV-related adversities. We aimed to estimate the cost-effectiveness of HPV vaccination for women living with HIV in a Chinese setting. A decision-analysis Markov model was developed to estimate the cost-effectiveness of 36 HPV vaccination strategies for women living with HIV aged 18-45 years, from the healthcare system perspective.

The acceptance of COVID-19 vaccines in Rwanda: a cross-sectional study.

The first reported case of Coronavirus Disease 2019 (COVID-19) in Rwanda occurred on March 14 2020. By the end of July 2024, a total of 133,518 individuals had tested positive for the infection, resulting in 1,468 deaths and 132,039 had fully recovered. The success of COVID-19 elimination in Rwanda hinges on the public's level of acceptance of the COVID-19 vaccination.

Global health 2050: the path to halving premature death by mid-century.

Global health 2050 (GH2050), a new report from the Lancet Commission on Investing in Health, finds that dramatic improvements in human welfare are achievable by mid-century with focused health investments. By 2050, countries that choose to do so can halve their probability of premature death (PPD)—the probability of dying before age 70—from their pre-pandemic level in 2019. We call this goal “50 by 50”: a 50% reduction in PPD by 2050.

"Not Only a Matter of Personal Interest"-Vaccination Narratives and the Model of Moral Motives in China and Germany.

Understanding vaccination decision-making processes is vital for guiding vaccine promotion within pandemic contexts and for routine immunization efforts. Vaccine-related attitudes influencing individual decision-making can be affected by broader cultural and normative contexts. We conducted 73 qualitative interviews with adults in China ( = 40) and Germany ( = 33) between December 2020 and April 2021 to understand COVID-19 vaccination intentions and preferences, and we analyzed transcripts using a five-step framework approach.