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The aim of this study is to evaluate the perioperative results of patients who receive robot-assisted thoracoscopic (RATS) modified segmentectomy and to compare the effectiveness and safety of this approach with those of traditional segmentectomy methods. A retrospective analysis was conducted on perioperative data from 587 consecutive patients diagnosed with early stage lung cancer who underwent robot-assisted thoracoscopic segmentectomy between January 2020 and September 2024. Using a 1:1 propensity score matching approach, 326 patients were paired based on clinical variables, such as age, sex, body weight, height, pulmonary function test results, and tumor size as measured by CT. Comparative assessments of perioperative outcomes and oncological parameters were performed between the matched groups. Of the 587 individuals included in the study, 178 underwent conventional segmentectomy (CS), while 409 received modified segmentectomy (MS). After applying propensity score matching, a total of 328 patients were retained for the final comparative analysis. The MS group demonstrated a significantly shorter operative time (83.72 ± 25.46 min vs. 121.01 ± 35.74 min, P < 0.001), lower total postoperative drainage volume (359.66 ± 413.70 ml vs. 527.98 ± 381.32 ml, P < 0.001), and a reduced postoperative hospital stay (3.76 ± 2.08 days vs. 4.69 ± 1.45 days, P < 0.001).Although the MS group exhibited a higher mean estimated blood loss, this difference did not reach statistical significance (58.87 ± 77.57 ml vs. 44.27 ± 55.35 ml, P = 0.051). Additionally, tumor size was significantly smaller in the MS cohort (8.67 ± 2.82 mm vs. 10.41 ± 4.08 mm, P < 0.001). Complete (R0) resection was achieved in all cases. The modified RATS segmentectomy offers significant benefits compared to conventional segmentectomy, such as shorter operative duration, reduced postoperative drainage, and a shorter postoperative hospital stay. These findings demonstrate the technical feasibility and potential advantages of this approach. However, further studies are needed to evaluate long-term oncological outcomes.
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http://dx.doi.org/10.1007/s11701-025-02640-7 | DOI Listing |
J Eat Disord
September 2025
Center for Nutrition and Therapy (NuT), University of Applied Sciences Muenster, Corrensstraße 25, 48149, Muenster, Germany.
Eating disorders are primarily associated with women and an obsession with thinness. Recent research and social media content show that men are also concerned about their body image, striving for a muscular and athletic physique. To investigate eating disorder tendencies among male content creators with a mesomorphic body type (N = 26), a social media analysis was conducted on Instagram and TikTok over four weeks.
View Article and Find Full Text PDFBMC Neurol
September 2025
Department of Neurology, University Hospital Schleswig-Holstein, Kiel, Germany.
Background: Parkinson's disease (PD) is characterized by motor symptoms altering gait domains such as slow walking speed, reduced step and stride length, and increased double support time. Gait disturbances occur in the early, mild to moderate, and advanced stages of the disease in both backward walking (BW) and forward walking (FW), but are more pronounced in BW. At this point, however, no information is available about BW performance and disease stages specified using the Hoehn and Yahr (H&Y) scale.
View Article and Find Full Text PDFSurg Endosc
September 2025
Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Background: Surgical resection is the cornerstone for early-stage non-small cell lung cancer (NSCLC), with lobectomy historically standard. Evolving techniques have spurred debate comparing lobectomy and segmentectomy. This study analyzed early postoperative patient-reported symptoms and functional status in patients with early NSCLC undergoing either procedure.
View Article and Find Full Text PDFBr J Cancer
September 2025
Centre for Cancer Screening, Prevention and Early Diagnosis, Wolfson Institute of Population Health, Queen Mary University of London, London, E1 1HH, UK.
Background: Multi-cancer detection (MCED) blood tests have the potential to screen for early-stage cancers. Understanding how people experience an MCED cancer signal result is vital prior to any future implementation. We explored experiences in a trial context.
View Article and Find Full Text PDFSignal Transduct Target Ther
September 2025
State Key Laboratory of Molecular Oncology & Department of Medical Oncology & Department of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Small-cell lung cancer (SCLC), an aggressive neuroendocrine tumor strongly associated with exposure to tobacco carcinogens, is characterized by early dissemination and dismal prognosis with a five-year overall survival of less than 7%. High-frequency gain-of-function mutations in oncogenes are rarely reported, and intratumor heterogeneity (ITH) remains to be determined in SCLC. Here, via multiomics analyses of 314 SCLCs, we found that the ASCL1/MKI67 and ASCL1/CRIP2 clusters accounted for 74.
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