Publications by authors named "Shanghao Liu"

Background: This study aimed to develop and validate a non-invasive model for screening advanced liver fibrosis and predicting liver-related outcomes in patients with type 2 diabetes mellitus (T2DM).

Methods: This study included patients with T2DM from five tertiary hospitals for the development and internal validation of a non-invasive model. Advanced liver fibrosis was defined as a liver stiffness measurement ≥12 kPa.

View Article and Find Full Text PDF

Background/aims: As the primary anthropometric measure in metabolic dysfunction-associated steatotic liver disease (MASLD), waist circumference (WC) may more accurately reflect the visceral fat distribution than body mass index (BMI). This study aimed to compare the prognostic value of BMI, WC and WC-related indices including waist-hip ratio (WHR), body shape index (BSI) and weight-adjusted-waist index (WWI) in individuals with MASLD.

Methods: The study population was derived from four large-scale cohorts: the National Health and Nutrition Examination Survey (NHANES 2017-2020 and NHANES III), the Kailuan Cohort and the UK Biobank Cohort.

View Article and Find Full Text PDF

Gemini surfactants have many potential applications in the viscosity reduction of heavy oils due to their unique structure, which appears to consist of two single-chain surfactant molecules. This paper introduces the viscosity reduction mechanism of gemini surfactants and the research progress of four types of Gemini surfactants used in the viscosity reduction of heavy oils at home and abroad. The study found that in the formation water containing calcium and magnesium ions with a salinity of more than 30000 mg/L, the added amount of gemini anionic surfactant was 0.

View Article and Find Full Text PDF

Background: Transjugular intrahepatic portosystemic shunt (TIPS) is an established procedure for managing portal hypertension in cirrhotic patients, but the impact of post-TIPS overt hepatic encephalopathy (OHE) on survival remains controversial. While its effect on short-term survival is well-documented, its long-term implications remain unclear.

Aims: This study aims to investigate the long-term impact of post-TIPS OHE on mortality in cirrhotic patients for variceal bleeding, focusing on the timing and predictive value of OHE beyond the first year post-TIPS.

View Article and Find Full Text PDF

Background/aims: A large percentage of patients undergoing esophagogastroduodenoscopy (EGD) screening do not have esophageal varices (EV) or have only small EV. We evaluated a large, international, multicenter cohort to develop a novel score, termed FIB-4plus, by combining the fibrosis-4 (FIB-4) score, liver stiffness measurement (LSM), and spleen stiffness measurement (SSM) to identify high-risk EV (HRV) in compensated cirrhosis.

Methods: This international cohort study involved patients with compensated cirrhosis from 17 Chinese hospitals and one Croatian institution (NCT04546360).

View Article and Find Full Text PDF

Baveno VII criteria (B7C) and Baveno VI criteria (B6C) have been widely used to estimate the risk of hepatic decompensation. However, the impact of age on these criteria warrants further investigation. The international, multicenter cohort study included 1138 patients with compensated cirrhosis (median follow-up of 40.

View Article and Find Full Text PDF
Article Synopsis
  • Minimal hepatic encephalopathy (MHE) significantly affects the quality of life and clinical outcomes in patients with cirrhosis, but it is difficult to diagnose promptly due to complex methods.
  • A study involving 673 healthy individuals and 905 cirrhosis patients established a diagnostic model using the Stroop test (Stroop-CN), which effectively detected MHE prevalence in both test and validation cohorts.
  • Results indicated that patients with MHE, particularly those with severe liver conditions, reported a lower quality of life compared to those without MHE, highlighting the need for accessible diagnostic tools like the Stroop-CN model.
View Article and Find Full Text PDF

Within the current process of large-scale dairy-cattle breeding, to address the problems of low recognition-accuracy and significant recognition-error associated with existing visual methods, we propose a method for recognizing the feeding behavior of dairy cows, one based on an improved RefineMask instance-segmentation model, and using high-quality detection and segmentation results to realize the recognition of the feeding behavior of dairy cows. Firstly, the input features are better extracted by incorporating the convolutional block attention module into the residual module of the feature extraction network. Secondly, an efficient channel attention module is incorporated into the neck design to achieve efficient integration of feature extraction while avoiding the surge of parameter volume computation.

View Article and Find Full Text PDF

Background: Noninvasive and early assessment of liver fibrosis is of great significance and is challenging. We aimed to evaluate the predictive performance and cost-effectiveness of the LiverRisk score for liver fibrosis and liver-related and diabetes-related mortality in the general population.

Methods: The general population from the NHANES 2017-March 2020, NHANES 1999-2018, and UK Biobank 2006-2010 were included in the cross-sectional cohort (n = 3,770), along with the NHANES follow-up cohort (n = 25,317) and the UK Biobank follow-up cohort (n = 17,259).

View Article and Find Full Text PDF

Hepatic venous pressure gradient (HVPG) is the gold standard for evaluating clinically significant portal hypertension (CSPH). However, reliable noninvasive methods are limited. Our study aims to investigate the diagnostic value of serum Golgi protein 73 (GP73) for CSPH in patients with compensated cirrhosis.

View Article and Find Full Text PDF

The cross-linking point of a conventional chemical cross-linking agent is fixed. Therefore, gels that are prepared with a conventional cross-linking agent have poor deformability, strength, shear resistance, and further properties. Some researchers have prepared a new cross-linking agent using cyclodextrin (CD).

View Article and Find Full Text PDF

Lost circulation is a world-class problem, and the contradiction between plugging and unplugging in reservoirs is a problem that needs to be solved urgently. The traditional LCM is not suitable for reservoirs and the complex subsequent operations. Currently, a self-degrading plugging material is proposed.

View Article and Find Full Text PDF

Background Currently, the hepatic venous pressure gradient (HVPG) remains the reference standard for diagnosis of clinically significant portal hypertension (CSPH) but is limited by its invasiveness and availability. Purpose To investigate a vascular geometric model for noninvasive diagnosis of CSPH (HVPG ≥10 mm Hg) in patients with liver cirrhosis for both contrast-enhanced CT and MRI. Materials and Methods In this retrospective study, consecutive patients with liver cirrhosis who underwent HVPG measurement from August 2016 to April 2019 were included.

View Article and Find Full Text PDF

Introduction: Post-hepatectomy liver failure (PHLF) is one of the most serious complications and causes of death in patients with hepatocellular carcinoma (HCC) after hepatectomy. This study aimed to develop a novel machine learning (ML) model based on the light gradient boosting machines (LightGBM) algorithm for predicting PHLF.

Methods: A total of 875 patients with HCC who underwent hepatectomy were randomized into a training cohort (n=612), a validation cohort (n=88), and a testing cohort (n=175).

View Article and Find Full Text PDF

Background And Aims: The prevalence of high-risk varices (HRV) is low among compensated cirrhotic patients undergoing EGD. Our study aimed to identify a novel machine learning (ML)-based model, named ML EGD, for ruling out HRV and avoiding unnecessary EGDs in patients with compensated cirrhosis.

Methods: An international cohort from 17 institutions from China, Singapore, and India were enrolled (CHESS2001).

View Article and Find Full Text PDF

In the study, agricultural waste bagasse was used as a bio-based flame retardant for reducing the flammability of epoxy. Specifically, an interpenetrating network (IPN) was formed through a ring opening reaction between the hydroxyl functional group of bagasse and the epoxy group of triglycidyl isocyanurate (TGIC), forming Bagasse@TGIC. Next, 9, 10-dihydro-9-oxa-10-phosphaphenanthrene 10-oxide (DOPO) was mixed with Bagasse@TGIC, inducing a reaction between the active hydrogen of DOPO and the epoxy group of TGIC, ultimately forming Bagasse@TGIC@DOPO with an IPN structure.

View Article and Find Full Text PDF

Fish scales (FSs) are fishery wastes that can cause environmental pollution. This study aimed to solve this environmental problem. FSs were used as a flame retardant for polymer materials, making them valuable.

View Article and Find Full Text PDF

Objective: To investigate the clinical characteristics, diagnosis and treatment methods of patients with myeloid sarcoma(MS). Methods: The clinical data, laboratory examination, clinical pathology and treatment methods of 15 patients with MS treated in the First Affiliated Hospital of Wannan Medical College from June 2012 to January 2020 were retrospectively analyzed.

Results: Among the 15 cases of MS, including eight males and seven females, the middle age of patients were 53(19 to 72). Among the 15 patients with MS, 4 showed solitary MS, while 11 showed secondary MS.

View Article and Find Full Text PDF

Ionic liquids (ILs) have very low volatility and are consequently considered as a green replacement to the organic solvents that have been widely used to date. The fire and explosion hazards of traditional organic solvents primarily depend on the combustibility of their vapors; therefore, ILs have been regarded as nonflammable for a long time because of their low volatility. However, recent studies have shown that ILs are flammable due to their thermal stability and consequently, the fire and explosion hazards of ILs limit their practical applications.

View Article and Find Full Text PDF