Colloidal InSb quantum dots (QDs) hold significant promise in infrared photodetection. However, the current InSb QDs suffer from poor carrier mobility and limited spectral response (<1.8 μm) due to complex surface structure and high sensitivity to hydrolysis and oxidation.
View Article and Find Full Text PDFSmall Methods
August 2025
Zinc selenide (ZnSe) quantum dots (QDs) emerge as promising eco-friendly materials for generating pure blue light emission due to their suitable bandgap. However, conventional synthetic methods of ZnSe QDs face persistent challenges in achieving isotropic growth and morphological uniformity. In this study, the roles of additives and precursors in the homogeneous growth of ZnSe QDs via a seed-mediated growth strategy are systematically investigated.
View Article and Find Full Text PDFWater-soluble quantum dots (QDs) face the challenges of photoluminescence (PL) blinking accompanied by photodegradation due to ligand desorption, which pose barriers to the implementation of QDs in their optical and optoelectronic applications. Here, we demonstrate the critical role of ligand adsorption/desorption dynamics in modulating PL blinking behaviors and photostability of water-soluble InP-based QDs at the single-dot level. Pre-adding excess ligands to water-soluble QDs can redirect ligand adsorption/desorption dynamics toward adsorption dominance and effectively passivate surface traps induced by dilution, converting PL blinking types from band-edge carrier blinking (BC-blinking) to Auger-blinking dominance.
View Article and Find Full Text PDFObjective: Microcirculatory disturbance is pathologically critical to acute pancreatitis (AP), which can be effectively alleviated by traditional Chinese medicine (TCM) formulas that activate blood flow. However, there has been no evidence-based research to date. Therefore, a well-designed systematic review and meta-analysis is necessary to elucidate the therapeutic transformative benefit of improving microcirculation during AP.
View Article and Find Full Text PDFAmid the rapid advancement in modern photonics and artificial intelligence, optoelectronic devices with enhanced functionalities and high performance hold great promise for complex photonic integrated circuits. Herein, a novel tunable differential photodetector (DPD) is developed based on a wide-/narrow-bandgap semiconductor heterojunction, featuring a large conduction band offset at the heterojunction interface. Benefiting from the unique band alignment at the heterojunction interface, this device exhibits interesting characteristics:1) It offers two tunable operational modes, freely switchable between "differential mode" and "normal mode" only by adjusting the bias voltages; 2) While operating in "differential mode" under zero bias, the DPD exhibits high detectivity (4.
View Article and Find Full Text PDFMotivation: The task of designing optimized messenger RNA (mRNA) sequences has received much attention in recent years, thanks to breakthroughs in mRNA vaccines during the COVID-19 pandemic. Because most previous work aimed to minimize the minimum free energy (MFE) of the mRNA in order to improve stability and protein expression, which only considers one particular structure per mRNA sequence, millions of alternative conformations in equilibrium are neglected. More importantly, we prefer an mRNA to populate multiple stable structures and be flexible among them during translation when the ribosome unwinds it.
View Article and Find Full Text PDFMultiplexed bioanalysis and deciphering their regulatory relationships have great significance for the diagnosis and treatment of diseases. In this study, a composite fluorescence encoding technology (CFET) combining spectrum and intensity was developed with tetrahedral DNA frameworks (TDFs) as carriers and four Alexa Fluor dyes (AF, AF, AF, and AF) as tags. Sixty-nine CFET codes could be established by altering the types and numbers of AF dyes at the vertexes of TDF.
View Article and Find Full Text PDFis the causative pathogen of infectious coryza. Isolates of obtained from China between 2008 and 2022 were characterized using 16S rRNA, , multilocus sequence typing, and biochemical tests to assess their genetic and biochemical diversity. All field isolates belonged to the same phylogenetic cluster together based on their 16S rRNA sequences.
View Article and Find Full Text PDFBACKGROUND Hashimoto's thyroiditis is a common autoimmune disease. There are currently few studies utilizing multi-parametric magnetic resonance imaging (MRI) to investigate diffuse thyroid lesions such as Hashimoto's thyroiditis. This study aims to explore the value of multi-parametric MRI in assessing the progression of Hashimoto's thyroiditis.
View Article and Find Full Text PDFTraditional manual sorting has problems such as low efficiency, low automation level and increased costs, which are difficult to meet the sorting challenges brought by the rapid development of logistics industry. In addition, it is difficult for existing parcel box detection algorithms to strike a balance between identification efficiency, identification accuracy and deployment cost. In this paper, we propose a 3D localization algorithm for rectangular packaging boxes based on deep learning, and design a lightweight parcel box detection model, the Efficient Object detection Network (EODNet).
View Article and Find Full Text PDFBackground: Plecanatide is a novel guanylate cyclase-C agonist for the treatment of functional constipation (FC). Its efficacy may vary across different racial populations.
Objective: This study aimed to comprehensively evaluate the efficacy, safety, and pharmacokinetics of plecanatide in Chinese patients with FC.
This paper presents a multifunctional terahertz device based on a dual-tunable structure incorporating graphene and vanadium oxide (VO). This device enables the switching between narrowband perfect absorption and ultra-broadband performance through the phase transition characteristics of VO and the adjustment of graphene Fermi level. Simulation results demonstrate that when VO is in its metallic state, the THz device exhibits ultra-broadband absorption, achieving a high absorption rate exceeding 0.
View Article and Find Full Text PDFStromal interaction molecule 1 (STIM1) is a Ca sensor in the endoplasmic reticulum (ER) membrane. The protein plays a crucial role in store-operated Ca entry (SOCE) by transducing ER Ca depletion signals to Ca release-activated Ca channel protein 1 (ORAI1) at the plasma membrane. Myotubularin related protein 7 (MTMR7) is a lipid phosphatase that dephosphorylates phosphoinositides.
View Article and Find Full Text PDFThe development of novel camouflage technologies is of great significance, exerting an impact on both fundamental science and diverse military and civilian applications. Effective camouflage aims to reduce the recognizability of an object, making it to effortlessly blend with the environment. For infrared camouflage, it necessitates precise control over surface emissivity and temperature to ensure that the target blends effectively with the surrounding infrared background.
View Article and Find Full Text PDFWe report the case of an 18-year-old female patient with bipolar disorder who developed recurrent acute myasthenia after taking lithium. The myasthenia resolved upon discontinuation of lithium, and this occurred twice. The results of the cranial magnetic resonance imaging (MRI), multiple sleep latency test, polysomnography, ambulatory electroencephalogram (EEG), and other tests were all negative.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
June 2025
Colloidal InSb quantum dots (QDs) are promising mid-infrared (MIR) photodetection materials due to their suitable bandgap, unparalleled room temperature electronic properties, environmental-friendly elemental composition, and facile solution processability. However, current InSb QDs suffer from limited spectral absorption within 2 µm, polydisperse QDs populations, and complex size-selective precipitation for further use, due to the lack of applicable growth theory and synthetic method. Here, we present a novel synthetic strategy for InSb QDs, which is featured by the initial formation of an amorphous intermediate and a subsequent stepwise crystallization process.
View Article and Find Full Text PDFThe joint use of multiple modalities for medical image processing has been widely studied in recent years. The fusion of information from different modalities has demonstrated the performance improvement for a lot of medical tasks. For nephropathy diagnosis, immunofluorescence (IF) is one of the most widely-used multi-modality medical images due to its ease of acquisition and the effectiveness for certain nephropathy.
View Article and Find Full Text PDFColloidal quantum dots (QDs) are promising emitters for biological applications because of their excellent fluorescence, convenient surface modification, and photostability. However, the toxic cadmium composition in the state-of-the-art QDs and their inferior properties in the aqueous phase greatly restrict further use. The performance of water-soluble indium phosphide (InP) QDs lags far behind those of Cd-containing counterparts due to the lack of effective surface protection.
View Article and Find Full Text PDFOpt Express
January 2025
Infrared (IR) photodetectors play a crucial role in modern technologies due to their ability to operate in various environmental conditions. This study developed high-performance InSe/GaAs interdiffusion heterostructure photodetectors with broadband response using liquid-phase method. It is believed that an InGaAs layer and InSe have been formed at the interface through the mutual diffusion of elements, resulting in a detection spectral range spanning from 0.
View Article and Find Full Text PDFThe task of RNA design given a target structure aims to find a sequence that can fold into that structure. It is a computationally hard problem where some version(s) have been proven to be NP-hard. As a result, heuristic methods such as local search have been popular for this task, but by only exploring a fixed number of candidates.
View Article and Find Full Text PDFNanophotonics
May 2024
Camouflage is a common technique in nature, enabling organisms to protect themselves from predators. The development of novel camouflage technologies, not only in fundamental science, but also in the fields of military and civilian applications, is of great significance. In this study, we propose a new type of deep-subwavelength four-layered meta-coating consisting of Si, Bi, Si, and Cr from top to bottom with total thickness of only ∼355 nm for visible-infrared compatible camouflage.
View Article and Find Full Text PDFThe heteroepitaxy of 2D materials with engineered bandgaps are crucial to broaden the spectral response for their integrated optoelectronic devices. However, it is a challenge to achieve the high-oriented epitaxy and integration of multicomponent 2D materials with varying lattice constants on the same substrate due to the limitation of lattice matching. Here, in-plane adaptive heteroepitaxy of a series of high-oriented 2D cesium bismuth halide (CsBiX X = I, Br, Cl) single crystals with varying lattice constants from 8.
View Article and Find Full Text PDFJ Endocrinol Invest
April 2025
Adv Sci (Weinh)
December 2024
As unique building blocks for advancing optoelectronics, 2D semiconducting transition metal dichalcogenides have garnered significant attention. However, most previously reported MoS photodetectors respond only to visible light with limited absorption, resulting in a narrow spectral response and low sensitivity. Here, a surrounding homojunction MoS photodetector featuring localized p-type nitrogen plasma doping on the surface of n-type MoS while preserving a high-mobility underlying channel for rapid carrier transport is engineered.
View Article and Find Full Text PDFFront Psychiatry
September 2024