Unilateral pharyngalgia as the dominant symptom in subacute thyroiditis: Case series and analysis of diagnostic pitfalls in clinical practice.

Subacute thyroiditis is a condition with varied and often misleading symptoms, which can lead to diagnostic delays and inappropriate treatment. This case series focuses on 32 patients who presented with unilateral pharyngalgia as the primary symptom and were ultimately diagnosed with subacute thyroiditis. The patients, aged 28-52 years with a female predominance (23 females and nine males), reported pharyngeal pain that lasted from 7 days to 3 months, with 19 having left-sided and 13 having right-sided initial pain.

Modulating the periodicity of plasmonic lithography by high-repetition-rate laser-driven heat accumulation.

We experimentally demonstrated the fabrication of highly regular laser-induced periodic surface structures (LIPSSs) on an amorphous silicon film coating on a copper substrate. Driven by femtosecond laser-plasmon interference-induced photochemical reactions, we achieved an increase of the LIPSS periodicity from 752 to 870 nm by heating the hybrid film from 298.15 to 368.

Efferocytosis in tissue engineering: A comprehensive review of emerging therapeutic strategies for enhanced tissue repair and regeneration.

This comprehensive review elucidates the critical role of efferocytosis in tissue repair and regeneration processes, while systematically exploring innovative approaches through which tissue engineering strategies can modulate efferocytosis to optimize these biological processes. The manuscript is structured to first establish a fundamental understanding of efferocytosis, encompassing its core concepts, molecular mechanisms, and physiological functions within tissue repair. Subsequently, it provides an in-depth analysis of the regulatory role of efferocytosis in inflammatory response modulation during tissue repair cascades.

SEM characterization technique for air-sensitive all-solid-state lithium battery materials.

Scanning electron microscopy (SEM) is an important tool for investigating the surface morphologies, chemical compositions, and failure mechanisms of functional materials. However, the microstructures of some materials change during the transfer to SEM, resulting in the inability to characterize them accurately because of the air-sensitive nature of the materials (e.g.

High-Rate CO-to-CH Photoreduction by Dual-Proton Hydrogenation Pathway Over Pd-Anchored Oxygen-Deficient ZnO Nanosheets.

Photoreduction of CO into CH usually comprises upto eight proton-coupled electron transfer steps, greatly reducing the conversion performance. Here, we report a new dual-proton hydrogenation pathway for CO-to-CH conversion, which can condense every two proton-coupled electron transfer steps into one single step. Also, we pioneer the use of in situ synchrotron-radiation vacuum ultraviolet photoionization mass spectrometry to distinguish the crucial HCOOH from COOH intermediates, overcoming the limitation of in situ Fourier-transform infrared spectroscopy.

Engineering the Stable BiO Species for Efficient Electroreduction of CO into Formic Acid at Ampere-Level Current.

BiO species have been identified as the most important active species for the electroreduction of CO to HCOOH over Bi-based materials. However, the BiO species are unstable under high reduction current/potential, limiting further industrial application. Herein, we constructed robust BiO species by incorporating sodion (Na) into Bi nanosheets (denoted as Na-Bi nanosheets).

Multifunctional metal-organic frameworks as promising nanomaterials for antimicrobial strategies.

Bacterial infections pose a serious threat to human health. While antibiotics have been effective in treating bacterial infectious diseases, antibiotic resistance significantly reduces their effectiveness. Therefore, it is crucial to develop new and effective antimicrobial strategies.

Role of Site-Specific Iron in Fe-Doped Nickel Hydroxide Toward Water Oxidation Revealed by Spatially Resolved Imaging at the Single-Particle Level.

Water electrolysis driven by renewable electricity is limited by the slow-kinetic oxygen evolution reaction (OER). NiFe-based hydroxides are considered promising non-noble electrocatalysts toward the OER but require profound insight into the role of site-specific iron incorporation. Herein, we determined the critical role of edge sites on single-crystalline NiFe-based hydroxide toward the OER using spatially resolved in situ single-particle imaging techniques.

Seven novel sesquiterpenes with hemostasis activities from leaves of Callicarpa nudiflora.

A pair of epimer with an unprecedented 4/7/6 tricyclic skeleton sesquiterpene (1 and 2) and five novel sesquiterpene (3-7) were isolated from Callicarpa nudiflora Hook. et Arn. Their structures were established by extensive spectroscopic analyses, single crystal X-ray diffraction, experimental electronic circular dichroism (ECD) spectra comparison and DP4+ probability analysis.

Adaptive All-Fiber Actuator for Human-Environment Interaction.

A closed-loop pathway of "efficient actuation-synchronous sensing-multimodal feedback" is crucial for actuators to adapt to complex scenarios and human-environment interactions. Strategies to reconcile mechanics-guaranteed adaptive actuation with multimodal responses and perceptivity remain challenging. Through a continuous electrospinning strategy to construct a reinforced fiber-interlocked interface, a bilayer fiber membrane (TCTR) actuator composed of highly aligned fiber and hierarchical structures is developed to obtain efficient photothermal performance (22.

A Novel Real-Time Threshold Algorithm for Closed-Loop Epilepsy Detection and Stimulation System.

Epilepsy, as a common brain disease, causes great pain and stress to patients around the world. At present, the main treatment methods are drug, surgical, and electrical stimulation therapies. Electrical stimulation has recently emerged as an alternative treatment for reducing symptomatic seizures.

Enhancement of the quality and in vitro starch digestibility of fried-free instant noodles with rapid rehydration using sourdough fermented with exopolysaccharide-producing Weissella confusa.

This study aimed to enhance the rehydration property of fried-free instant noodles using a fermentation method with exopolysaccharide-producing Weissella confusa, thereby improving their quality. The effect of sourdough fermented with W. confusa on the rehydration property, cooking qualities and in vitro starch digestibility of fried-free instant noodles was investigated.

Microfiber Actuators With Hot-Pressing-Programmable Mechano-Photothermal Responses for Electromagnetic Perception.

Electromagnetic radiation (EMR) is a ubiquitous harm and hard to detect dynamically in multiple scenarios. A mechano-photothermal cooperative microfiber film (MFF) actuator is developed that can synchronously detect EMR with high reliability. The programmable actuation is deployed by a hot-pressing methodology, achieving the MFF with moderate modulus (378 MPa) and superior toughness (87.

Paper-Recorded ECG Digitization Method with Automatic Reference Voltage Selection for Telemonitoring and Diagnosis.

In electrocardiograms (ECGs), multiple forms of encryption and preservation formats create difficulties for data sharing and retrospective disease analysis. Additionally, photography and storage using mobile devices are convenient, but the images acquired contain different noise interferences. To address this problem, a suite of novel methodologies was proposed for converting paper-recorded ECGs into digital data.

Atomic Defects Engineering Boosts Urea Synthesis toward Carbon Dioxide and Nitrate Coelectroreduction.

The atomic defect engineering could feasibly decorate the chemical behaviors of reaction intermediates to regulate catalytic performance. Herein, we created oxygen vacancies on the surface of In(OH) nanobelts for efficient urea electrosynthesis. When the oxygen vacancies were constructed on the surface of the In(OH) nanobelts, the faradaic efficiency for urea reached 80.

Three New Steroids from the Roots of Marsdenia tenacissima.

Three undescribed pregnane steroids, 12β-O-4-hydroxybenzoyl tenacigenin D (1), 12β-O-4-hydroxybenzoyl tenacigenin A (2), and 11α-nicotinoyl-17β-marsdenin (3), along with two known analogues (4 and 5), were isolated from the roots of Marsdenia tenacissima. Their structures were elucidated using one- and two-dimensional NMR, high-resolution electron ionization-mass spectrometry, single-crystal X-ray diffraction data, and experimental and density-functional-theory-calculated electronic circular dichroism measurements. All isolated compounds were evaluated for their cytotoxic activities against human lung cancer cells (A549), ovarian carcinoma cells (SKOV-3), gastric cancer cells (MGC 803) and breast cancer cells (MCF-7).

Optimizing the Intermediates Adsorption by Manipulating the Second Coordination Shell of Ir Single Atoms for Efficient Water Oxidation.

The precise regulation of single-atom catalysts (SACs) with the desired local chemical environment is vital to elucidate the relationship between the SACs structure and the catalytic performance. The debate on the effect of the local coordination environment is quite complicated even for the SACs with the same composition and chemical nature, calling for increased attention on the regulation of the second coordination shell. For oxide-supported SACs, it remains a significant challenge to precisely manipulate the second coordination shell of single atoms supported on oxides due to the structural robustness of oxides.

Nitrogen-Mediated Promotion of Cobalt-Based Oxygen Evolution Catalyst for Practical Anion-Exchange Membrane Electrolysis.

Scarce and expensive iridium oxide is still the cornerstone catalyst of polymer-electrolyte membrane electrolyzers for green hydrogen production because of its exceptional stability under industrially relevant oxygen evolution reaction (OER) conditions. Earth-abundant transition metal oxides used for this task, however, show poor long-term stability. We demonstrate here the use of nitrogen-doped cobalt oxide as an effective iridium substitute.

Facile synthesis of a hydrazone-based zinc(ii) complex for ferroptosis-augmented sonodynamic therapy.

Sonodynamic therapy (SDT), as a novel non-invasive cancer treatment modality derived from photodynamic therapy (PDT), has drawn much attention due to its unique advantages for the treatment of deep tumors. Zinc-based complexes have shown great clinical prospect in PDT due to their excellent photodynamic activity and biosafety. However, their application in SDT has lagged seriously behind.

Hydrogel-exosome system in tissue engineering: A promising therapeutic strategy.

Characterized by their pivotal roles in cell-to-cell communication, cell proliferation, and immune regulation during tissue repair, exosomes have emerged as a promising avenue for "cell-free therapy" in clinical applications. Hydrogels, possessing commendable biocompatibility, degradability, adjustability, and physical properties akin to biological tissues, have also found extensive utility in tissue engineering and regenerative repair. The synergistic combination of exosomes and hydrogels holds the potential not only to enhance the efficiency of exosomes but also to collaboratively advance the tissue repair process.

Hydrogel-based immunoregulation of macrophages for tissue repair and regeneration.

The rational design of hydrogel materials to modulate the immune microenvironment has emerged as a pivotal approach in expediting tissue repair and regeneration. Within the immune microenvironment, an array of immune cells exists, with macrophages gaining prominence in the field of tissue repair and regeneration due to their roles in cytokine regulation to promote regeneration, maintain tissue homeostasis, and facilitate repair. Macrophages can be categorized into two types: classically activated M1 (pro-inflammatory) and alternatively activated M2 (anti-inflammatory and pro-repair).

Breaking the Scaling Relationship in C-N Coupling via the Doping Effects for Efficient Urea Electrosynthesis.

Electrochemical C-N coupling reaction based on carbon dioxide and nitrate have been emerged as a new "green synthetic strategy" for the synthesis of urea, but the catalytic efficiency is seriously restricted by the inherent scaling relations of adsorption energies of the active sites, the improvement of catalytic activity is frequently accompanied by the decrease in selectivity. Herein, a doping engineering strategy was proposed to break the scaling relationship of intermediate binding and minimize the kinetic barrier of C-N coupling. A thus designed SrCoRuO catalyst achieves a urea yield rate of 1522 μg h mg and faradic efficiency of 34.