Correction: New media, lifestyle transformation, and public health: unraveling the digital divide in China.

[This corrects the article DOI: 10.3389/fpubh.2025.

Nsp2 replicase-mediated viral uncoating in porcine alveolar macrophages contributes to the attenuation of PRRSV-2 live attenuated vaccine.

Type 2 porcine reproductive and respiratory syndrome virus (PRRSV-2) poses a major threat to global swine production. While live attenuated vaccines (LAVs) remain the most effective countermeasure, the molecular mechanisms underlying PRRSV-2 attenuation remain enigmatic. Here, we reveal that PRRSV-2 LAVs exhibit impaired replication in their primary cellular targets-porcine alveolar macrophages (PAMs), with viral uncoating defects being the critical replication barrier.

Synergizing acid-base sites and lattice distortion of amorphous basic cobalt carbonate for transfer hydrogenation.

The amorphous basic cobalt carbonate synthesized a facile precipitation method exhibits much higher activity (97.1% conversion and 98.0% selectivity) in cinnamaldehyde transfer hydrogenation compared to cobalt oxide catalysts, due to the high-density acid-base sites and lattice distortion.

New media, lifestyle transformation, and public health: unraveling the digital divide in China.

New media has profoundly reshaped everyday life in China, particularly influencing leisure lifestyles and raising new public health concerns. As the use of new media continues to rise, its impact on social behavior and well-being has become an urgent area of study. This study uses data from the 2018 Chinese General Social Survey (CGSS) and employs factor analysis and Oaxaca-Blinder decomposition to assess the impact of new media usage on lifestyle diversity across different social groups.

Cryo-EM structural elucidation and molecular mechanism of the GPR133-G13 signaling complex.

GPR133 is an adhesion-class G protein-coupled receptor (GPCR) that has recently been de-orphanized. Its functions are complex and multifaceted. While GPR133 is primarily recognized for coupling with the Gs subunit to mediate elevated intracellular cAMP levels, its potential engagement with alternative signaling pathways remains poorly characterized.

Development of core competency evaluation index system for informatics nurses in China: a Delphi study.

Objective: To develop a scientific and systematic core competency evaluation index system for informatics nurses in China. The goal is to support their training, assessment and performance evaluation.

Methods: An initial set of evaluation indicators was created based on a review of existing literature and semi-structured interviews.

High temperature and ozone co-exposure induces cardiovascular damage in mice: Insights from gut microbiome and plasma metabolomics.

Epidemiological studies have demonstrated associations between heat waves, ozone (O) pollution, and cardiovascular morbidity and mortality. High temperature (HT) and higher levels of O usually co-exist in the atmosphere. However, few studies have investigated the adverse effects of HT and O co-exposure on cardiovascular system.

Transglutaminase-enhanced walnut protein isolate gels: Synergistic effects of double modification on gelation and riboflavin encapsulation.

This study investigated the effects of a double-modification process involving Alcalase hydrolysis (1, 3, and 5 min) and ultrasound treatment (360 W, 15 min) on the functional properties and characteristics of walnut protein isolate (WPI). Among the treatments, WPI hydrolyzed for 3 min and subjected to ultrasound (WEU-3) demonstrated the highest water-holding capacity of 3.66 g/g and solubility of 34.

LncRNA XIST inhibits mitophagy and increases mitochondrial dysfunction by promoting BNIP3 promoter methylation to facilitate the progression of KBD.

The primary mechanisms underlying cartilage destruction in Kashin-Beck disease (KBD) involve excessive chondrocyte death and extracellular matrix (ECM) degradation. While long non-coding RNA XIST (lncRNA XIST) has been implicated in promoting chondrocyte injury in osteoarthritis (OA), its role in KBD-related chondrocyte injury remains poorly understood. In this study, joint tissues were collected from four healthy and four KBD-affected children, as well as five healthy and five KBD-affected adults, to assess the expression of lncRNA XIST.

Macrophage migration inhibitory factor in inflammasome formation and macrophage recruitment by cervical squamous cell carcinoma cells.

Despite the demonstrated efficacy of immune checkpoint blockade therapies in various types of cancer, their efficacy in cervical cancer is limited. A crucial pro-inflammatory cytokine, macrophage migration inhibitory factor (MIF), is highly expressed in various types of cancers and contributes to tumor progression via the regulation of inflammatory responses and the tumor microenvironment. The present study aimed to explore the role of MIF in cervical squamous cell carcinoma (CSCC).

Identification, structure, and agonist design of an androgen membrane receptor.

Androgens, such as 5α-dihydrotestosterone (5α-DHT), regulate numerous functions by binding to nuclear androgen receptors (ARs) and potential unknown membrane receptors. Here, we report that the androgen 5α-DHT activates membrane receptor GPR133 in muscle cells, thereby increasing intracellular cyclic AMP (cAMP) levels and enhancing muscle strength. Further cryoelectron microscopy (cryo-EM) structural analysis of GPR133-Gs in complex with 5α-DHT or its derivative methenolone (MET) reveals the structural basis for androgen recognition.

Improvement of antioxidant capacity, aroma quality, and antifungal ability of cherry by phenyllactic acid treatment during low temperature storage.

Introduction: Sweet cherries ( L.) are highly valued for their taste and nutrients but are prone to decay due to their delicate skin and high respiration rate. Traditional chemical preservatives have drawbacks like residues and resistance, prompting the search for natural alternatives.

Improving the storage quality of sweet cherry by natamycin nanoparticles/chitosan coating.

In this study, natamycin nanoparticles were prepared by anti-solvent method, and natamycin nanoparticles/chitosan coating was prepared and investigated for the preservation of sweet cherry. The results of particle size showed that the prepared natamycin nanoparticles were nano-sized, with a particle size of 209 ± 10 nm. The results of scanning electron microscope (SEM) showed that the apparent morphology was a uniform spherical structure.

Effects of solid-state fermentation product of yeast supplementation on liver and intestinal health, and resistance of common carp () against spring viraemia carp virus.

This study aimed to investigate the effects of solid-state fermentation products of yeast (SFPY) on liver and intestinal health and disease resistance of common carp (). A total of 200 common carp with an initial average weight of 2.55 ± 0.

Characterization of a marine endolysin LysVPB against Vibrio parahaemolyticus.

Currently, there is an urgent to develop safe and environmentally friendly alternatives to antibiotics for combating Vibrio parahaemolyticus. Endolysins are considered promising antibacterial agents due to their desirable range of action and ability to deal with antibiotic-resistant bacteria. While numerous Vibrio phages have been identified, the research on their endolysins is still in its infancy.

Generalized Nash Equilibrium Seeking for Noncooperative Game With Different Monotonicities by Adaptive Neurodynamic Algorithm.

This article proposes a novel adaptive neurodynamic algorithm (ANA) to seek generalized Nash equilibrium (GNE) of the noncooperative constrained game with different monotone conditions. In the ANA, the adaptive penalty term, which acts as trajectory-dependent penalty parameters, evolves based on the degree of constraints violation until the trajectory enters the action set of noncooperative game. It is shown that the trajectory of the ANA enters the action set in finite time benefited from the adaptive penalty term.

Recurrent inhibition refines mental templates to optimize perceptual decisions.

Translating sensory inputs to perceptual decisions relies on building internal representations of features critical for solving complex tasks. Yet, we still lack a mechanistic account of how the brain forms these mental templates of task-relevant features to optimize decision-making. Here, we provide evidence for recurrent inhibition: an experience-dependent plasticity mechanism that refines mental templates by enhancing γ-aminobutyric acid (GABA)-mediated (GABAergic) inhibition and recurrent processing in superficial visual cortex layers.

Bi-modified Cu-Based Catalysts for Acetylene Hydrogenation: Leveraging Dispersion and Hydrogen Spillover.

Removing trace acetylene from the ethylene stream through selective hydrogenation is a crucial process in the production of polymer-grade ethylene. However, achieving high selectivity while maintaining high activity remains a significant challenge, especially for nonprecious metal catalysts. Herein, the trade-off between activity and selectivity is solved by synergizing enhanced dispersion and hydrogen spillover.

The wavelength dependence of oxygen-evolving complex inactivation in Zosteramarina.

Zostera marina, a critical keystone marine angiosperm species in coastal seagrass meadows, possesses a photosensitive oxygen evolving complex (OEC). In harsh environments, the photoinactivation of the Z. marina OEC may lead to population declines.

Collective plasticity of binocular interactions in the adult visual system.

Binocular visual plasticity can be initiated via either bottom-up or top-down mechanisms, but it is unknown if these two forms of adult plasticity can be independently combined. In seven participants with normal binocular vision, sensory eye dominance was assessed using a binocular rivalry task, before and after a period of monocular deprivation and with and without selective attention directed towards one eye. On each trial, participants reported the dominant monocular target and the inter-ocular contrast difference between the stimuli was systematically altered to obtain estimates of ocular dominance.

Potentials of ribosomopathy gene as pharmaceutical targets for cancer treatment.

Ribosomopathies encompass a spectrum of disorders arising from impaired ribosome biogenesis and reduced functionality. Mutation or dysexpression of the genes that disturb any finely regulated steps of ribosome biogenesis can result in different types of ribosomopathies in clinic, collectively known as ribosomopathy genes. Emerging data suggest that ribosomopathy patients exhibit a significantly heightened susceptibility to cancer.

Comprehensive analysis of the effect of etiolated tea cultivars and harvest seasons on volatile compounds and antioxidant capacity in steamed green teas.

To explore the effects of harvest seasons and etiolated cultivars on the volatile compounds of steamed green teas, this study analyzed comprehensively the volatile compounds of steamed green teas using simultaneous distillation extraction-gas chromatography-mass spectrometry (SDE-GC-MS) and chemometrics analytical techniques in combination with odor activity value (OAV). Additionally, the antioxidant capacity of the steamed green teas was evaluated. The results showed that 95 volatile compounds were identified, among which aldehydes, ketones, alcohols, and acids were the main types in steamed green teas made from etiolated tea cultivars.

The Flavor Characteristics, Antioxidant Capability, and Storage Year Discrimination Based on Backpropagation Neural Network of Organic Green Tea () during Long-Term Storage.

The storage period of tea is a major factor affecting tea quality. However, the effect of storage years on the non-volatile major functional components and quality of green tea remains largely unknown. In this study, a comparative analysis of organic green teas with varying storage years (1-16 years) was conducted by quantifying 47 functional components, using electronic tongue and chromatic aberration technology, alongside an evaluation of antioxidative capacity.