Flavor profiling and optimization of large yellow croaker () in recirculating aquaculture systems: Effects of exercise intensity assessed by advanced analytical techniques.

Exercise training is important for improving muscle flavor in RAS-farmed fish, but its effects on the muscle flavor of remain unclear. This study investigated how different swimming intensities (0.4, 0.

A Review of Bioactive Components and Pharmacological Effects of .

, a distinguished traditional medicinal herb, has long been recognized for its purported benefits in promoting physical well-being, enhancing stamina, and boosting vitality. However, the mechanistic underpinnings of its antitumor activities and other therapeutic effects remain incompletely understood. Historically, the activation of host immune responses was widely regarded as the sole mechanism by which exerts its anticancer effects.

CoHMGR2 as a Critical Regulator of Squalene Biosynthesis Key Period in Camellia oleifera Seed Kernels.

Squalene is an extremely valuable medicinal substance. In addition to being valued for its high content of unsaturated fatty acids, Camellia oleifera is also highly regarded for its rich squalene content in the seed kernels. Comparing the squalene contents within Camellia species, it was found that the content in the seed oil of C.

Genome-wide identification of the RALF gene family in Camellia oleifera Abel. and the potentiality of CoRALF50 in pollen tube growth.

Rapid alkalinization factors (RALFs) play meaningful roles in the pollination and fertilization. However, the identification and study of Camellia RALFs is lacking, particularly the function of the RALF family in regulating self-incompatibility pollen tube growth. Herein, we identified 50 RALF genes from Camellia oleifera genome, and classified them into three groups: Clades Ⅰ, Ⅱ, and Ⅲ, with 11, 12, and 27 members being included, respectively.

Effects of grass cultivation on soil fertility and labile carbon fractions in forests.

Exploring the characteristics of soil fertility and labile carbon fractions under different cover crop cultivation modes can provide scientific references for optimizing management of forests. We conducted a three-year field experiment with cover crop of (DD), (SY), (YK), (BJ), with clean tillage as the control (CK), to investigate the changes of physical and chemical properties of topsoil (0-20 cm), the integrated fertility index (IFI), carbon pool management index, labile carbon fractions, and the yield per plant. The results showed that grass cultivation significantly reduced soil bulk density (BD) and increased the content of soil organic carbon (SOC), nitrate-nitrogen, total potassium, and available potassium.

Polygonati Rhizoma polysaccharide suppresses microglial activation and promotes functional recovery of spinal cord via improving intestinal microbiota.

Spinal cord injury (SCI) can disrupt the gut microbiome and metabolites, impacting prognosis, substantially impairing quality of life, and leading to high socioeconomic costs (Jing et al., 2021). Recent studies indicate that plant polysaccharides exhibit antimicrobial, anti-inflammatory, and immune-enhancing properties, contributing positively to various neurological disorders; however, their role in SCI remains uncertain (Hou et al.

[Spatial and Temporal Differences and Influencing Factors of Mobile Genetic Elements in Urban and Suburban River Sediments in Shijiazhuang City].

With the widespread use of antibiotics in medicine and agriculture, the spread of antibiotic resistance genes （ARGs） in the environment has become a serious threat to ecological balance and human health, particularly for its role in facilitating the emergence of multidrug-resistant pathogens. The study of riverine environments as a major transmission route for ARGs and closely related mobile genetic elements （MGEs） is of great importance. MGEs exacerbate the spread of resistance genes by facilitating the horizontal transfer of ARGs in bacterial populations.

Electrochemical detection of tetracycline by zinc oxide modified with molecularly-imprinted polymers.

An efficient electrochemical molecularly imprinted sensor for the detection of tetracycline (TC) was prepared using ZnO/MIP. ZnO nanomaterials with large surface area improved the electrochemical detection performance and also increased the binding sites of the TC molecularly imprinted polymeric membrane. The TC molecularly imprinted polymeric membrane with pyrrole as the functional monomer specifically binds to TC and thus detects TC in the sample.

Peptidomic profiling of mesenchymal stem cell-derived extracellular vesicles and anti-inflammatory activity of degraded peptides.

Mesenchymal stem cell derived extracellular vesicles (MSC-EVs) are key paracrine mediators involved in various autoimmune diseases. While current research on EVs predominantly focuses on their protein and nucleic acid components, small peptides received less attention. In this study, we found IFN-γ-treated MSC-EVs, as engineered EVs, exhibit better anti-inflammatory effects both in vitro and in vivo.

Effects of different shade treatments on Melaleuca seedling growth and physiological properties.

In light of the detrimental effects of global warming, exacerbated by the intense sunlight and high temperatures prevalent during summer in southern China, on the growth of Melaleuca alternifolia (M. alternifolia) seedlings, this study sets out to examine the impact of various shading treatments on the growth and physiological attributes of M. alternifolia seedlings, with the aim of determining the optimum shading level.

De novo assembly of the complete mitochondrial genomes of two Camellia-oil tree species reveals their multibranch conformation and evolutionary relationships.

Camellia-oil trees are economically valuable, oil-rich species within the genus Camellia, family Theaceae. Among these species, C. oleifera, a member of Section Oleifera in the genus, is the most extensively cultivated in China.

Scale-Up of Human Amniotic Epithelial Cells Through Regulation of Epithelial-Mesenchymal Plasticity Under Defined Conditions.

Human amniotic epithelial cells (hAECs) have shown excellent efficacy in clinical research and have prospective applications in the treatment of many diseases. However, the properties of the hAECs and their proliferative mechanisms remain unclear. Here, single-cell RNA sequencing (scRNA-seq) is performed on hAECs obtained from amniotic tissues at different gestational ages and passages during in vitro culture.

Models of fibrolamellar carcinomas, tools for evaluation of a new era of treatments.

Fibrolamellar carcinoma (FLC) is a rare but fatal cancer that occurs primarily in young people. There are currently no known effective treatments, although several promising treatments appear to be in development. Genetic studies have confirmed that almost all FLC tumors have a fusion protein marker (DNAJB1-PRKACA) encoded by a fusion gene (DNAJB1-PRKACA); It is currently accepted as a diagnostic criterion for FLCs.

Hormonally and chemically defined expansion conditions for organoids of biliary tree Stem Cells.

Wholly defined expansion conditions for biliary tree stem cell (BTSC) organoids were established, consisting of a defined proliferative medium (DPM) used in combination with soft hyaluronan hydrogels. The DPM consisted of commercially available Kubota's Medium (KM), to which a set of small molecules, particular paracrine signals, and heparan sulfate (HS) were added. The small molecules used were DNA methyltransferase inhibitor (RG108), TGF- β Type I receptor inhibitor (A83-01), adenylate cyclase activator (Forskolin), and L-type Ca channel agonist (Bay K8644).

Research on the Cell Wall Breaking and Subcritical Extraction of Astaxanthin from .

This study focused on developing an effective cell wall-breaking method for , followed by utilizing subcritical fluid extraction to isolate, extract, and concentrate astaxanthin from the complex fermentation products of . A comprehensive comparison of seven distinct methods for disrupting cell walls, including dimethyl sulfoxide treatment, lactic acid treatment, sodium hydroxide treatment, -glucanase enzymatic digestion, -mannanase enzymatic digestion, and a combined enzymatic treatment involving both -mannanase and -glucanase was conducted. The results identified the lactic acid method as the most effective in disrupting the cell walls of .

[Antibiotic Pollution and Its Effects on the Spatiotemporal Variation in Microbial Community Structure and Functional Genes in Sediment of Baiyangdian Lake].

Microbial communities play an important role in water quality regulation and biogeochemical cycles in lakes, and their community structure and function are affected by environmental factors. Therein, antibiotics affect the abundance, diversity, composition, and function of microbial communities. In this study, Baiyangdian Lake was selected as the study area.

Efficient conversion of distillers grains as feed ingredient by synergy of probiotics and enzymes.

The direct feeding value of distillers grains is low due to the presence of higher cellulose, lignin and anti-nutritional factors such as mannan and xylan. In this study, complex enzymes and probiotic flora based on "probiotic enzyme synergy" technology were used to produce fermented distillers grains. The optimal substrate ratio, moisture content, fermentation time and temperature were determined.

[Spatial and Temporal Distribution of Antibiotic Resistance Genes in Different River Sediments in Typical Cities: A Case Study of Shijiazhuang].

Rivers are important reservoirs of antibiotic resistance genes (ARGs). However, most current studies have focused on the temporal and spatial distribution, and data on the differences in the species and abundance of ARGs between urban and rural rivers is still lacking for certain areas. In view of this, two rural rivers and three urban rivers were selected in Shijiazhuang City.

Source apportionment and specific-source-site risk of quinolone antibiotics for effluent-receiving urban rivers and groundwater in a city, China.

There is a large surface-groundwater exchange downstream of wastewater treatment plants (WWTPs), and antibiotics upstream may influence sites downstream of rivers. Thus, samples from 9 effluent-receiving urban rivers (ERURs) and 12 groundwater sites were collected in Shijiazhuang City in December 2020 and April 2021. For ERURs, 8 out of 13 target quinolone antibiotics (QNs) were detected, and the total concentration of QNs in December and April were 100.

Lagrangian Partition Functions Subject to a Fixed Spatial Volume Constraint in the Lovelock Theory.

We evaluate here the quantum gravity partition function that counts the dimension of the Hilbert space of a simply connected spatial region of a fixed proper volume in the context of Lovelock gravity, generalizing the results for Einstein gravity. It is found that there are sphere saddle metrics for a partition function at a fixed spatial volume in Lovelock theory. Those stationary points take exactly the same forms as in Einstein gravity.

Improvement in caffeic acid and ferulic acid extraction by oscillation-assisted mild hydrothermal pretreatment from sorghum straws.

This work investigated the effect of oscillation-assisted hydrothermal process on extraction of caffeic acid and ferulic acid from sorghum straws. The results showed that the oscillation-assisted hydrothermal process efficiently improved extraction of caffeic acid and ferulic acid. The oscillation-assisted hydrothermal process resulted in the extraction rates of 1275.

[Spatial-temporal Changes and Driving Factors of Soil Microbial Communities in a Typical City of North China Plain].

The structure and function of microbial communities are affected by several environmental factors. To clarify the spatial-temporal changes and main influencing factors of soil microbial communities in a typical pharmaceutical city, it is urgent to study the spatial-temporal changes in microbial communities in soils for typical cities. Shijiazhuang City was selected as the study area, and 12 sampling sites were selected.

[Source Apportionment and Source-specific Risk of Typical Antibiotics in Baiyangdian Lake].

The current situation of antibiotic pollution in lakes is critical. At present, most of the previous studies on antibiotics in lakes have focused on the spatiotemporal distribution and risk assessment, while less attention has been paid to the source apportionment. Ultra-high performance liquid chromatography-mass spectrometry was used to determine the concentration of tetracyclines (TCs), sulfonamides (SAs), and quinolones (QNs) in the samples.

[Source Analysis and Health Risk Assessment of Heavy Metals in the Groundwater of Shijiazhuang, a Typical City in North China Plain].

Increasing attention has been paid to the heavy metal pollution in groundwater. The source analysis and risk assessment of heavy metals will provide data and method support for the targeted control of heavy metal pollution in groundwater. In this study, 20 sampling sites were selected in Shijiazhuang City.