Relationship between illness perception and post-traumatic stress disorder among adults with burn: The mediation role of cognitive emotion regulation.

Unlabelled: This current study explored the relationship between illness perception (IP) and post-traumatic stress disorder (PTSD), and the mediation role of cognitive emotion regulation (CER) among patients with burns.

Methods: This study is multicenter and cross-sectional. Patients with a history of burn injury at three tertiary hospitals in mainland China were selected through purposeful sampling.

The Long Non-Coding RNA linc01105 Inhibits Gastric Cancer Growth and Metastasis by Regulating the miR-650/TCEA3 Axis.

Gastric cancer (GC) is a widespread cancerous disease with an unfavorable prognosis, linc01105 appears to have a significant connection with the development of GC, but the precise regulatory mechanism remains obscure. Real-time quantitative polymerase chain reaction (RT-qPCR) was utilized to determine the expression of linc01105, miR-650, and TCEA3. Proliferative capacity of GC cells was measured by CCK8.

D-orbital Reconstruction Achieves Low Charge Overpotential in Li-oxygen Batteries.

Charge overpotential for oxygen evolution reaction is a crucial parameter for the energy conversion efficiency of lithium-oxygen (Li-O) batteries. So far, the realization of low charge overpotential via catalyst design is a grand challenge in this field, which usually exceeds 0.25 V.

Balancing Intermediates Formation on Atomically Pd-Bridged Cu/CuO Interfaces for Kinetics-Matching Electrocatalytic C─N Coupling Reaction.

The electrochemical C─N coupling of CO and nitrogenous species provides a promising approach for synthesizing valuable chemicals such as urea, amides, and other C─N compounds. However, the unbalanced formation of C- and N-intermediates results in slow C─N coupling kinetics. Herein, we report an atomically Pd-bridged Cu/CuO (Pd-Cu/CuO) catalyst, synthesized through the in situ electrochemical reconstruction of Pd-CuTe nanosheets.

Causal association between metabolic syndrome and ovarian dysfunction: a bidirectional two-sample mendelian randomization.

Background: The relationship between Metabolic Syndrome (MetS) and ovarian dysfunction has been widely reported in observational studies, yet it remains not fully understood. This study employs genetic prediction methods and utilizes summary data from genome-wide association studies (GWAS) to investigate this causal link.

Methods: We employed a bidirectional two-sample Mendelian Randomization (MR) analysis utilizing MetS and ovarian dysfunction summary data from GWAS.

LncRNA HOTAIR promotes aerobic glycolysis by recruiting Lin28 to induce inflammation and apoptosis in acute lung injury.

Acute lung injury (ALI) is a life-threatening condition with high rates of morbidity and mortality. Recently, there has been growing evidence suggesting a link between lncRNA HOTAIR and ALI. Nonetheless, the precise role and mechanism of lncRNA HOTAIR in ALI remain to be fully elucidated.

The Role of Illness Perception and Help-Seeking Attitudes on Positive Psychological Well-Being and Quality of Life in People With Chronic Wounds.

Chronic wounds are a substantial health burden, adversely affecting patients' overall quality of life. This study explored the association between positive psychological well-being and quality of life and the mediating roles of illness perceptions and attitudes toward medical help-seeking among people with chronic wounds. A total of 208 people with chronic wounds from three hospitals in China were recruited.

Identification of USP2 as a novel target to induce degradation of KRAS in myeloma cells.

Inducing the degradation of KRAS represents a novel strategy to combat cancers with KRAS mutation. In this study, we identify ubiquitin-specific protease 2 (USP2) as a novel deubiquitinating enzyme of KRAS in multiple myeloma (MM). Specifically, we demonstrate that gambogic acid (GA) forms a covalent bond with the cysteine 284 residue of USP2 through an allosteric pocket, inhibiting its deubiquitinating activity.

Interfacial oxygen bridges engineering between NbO and graphene towards advanced sodium ion capacitors.

NbO has become a focus of research for its suitability as an anode material in sodium ion capacitors (SICs), due to its open ionic channels. The integration of NbO with reduced graphene oxide (rGO) is known to boost its electrical conductivity. However, the sluggish interfacial charge transfer kinetics and interface collapse of NbO/rGO pose challenges to its rate capability and durability.

Atomic-Scale Tailoring C-N Coupling Sites for Efficient Acetamide Electrosynthesis over Cu-Anchored Boron Nitride Nanosheets.

Electrochemical conversion of carbon and nitrogen sources into valuable chemicals provides a promising strategy for mitigating CO emissions and tackling pollutants. However, efficiently scaling up C-N products beyond basic compounds like urea remains a significant challenge. Herein, we upgrade the C-N coupling for acetamide synthesis through coreducing CO and nitrate (NO) on atomic-scale Cu dispersed on boron nitride (Cu/BN) nanosheets.

TIGAR relieves PCOS by inhibiting granulosa cell apoptosis and oxidative stress through activating Nrf2.

This study aimed to elucidate the role of TP53-induced glycolysis and apoptosis regulator (TIGAR) in polycystic ovary syndrome (PCOS). A rat model PCOS was constructed by subcutaneous injection with dehydroepiandrosterone (DHEA). Follicular atresia and reduced granular cells (GCs) in ovaries suggested successful modeling.

Quantitative Analysis of the Causes of Falls in Adult Hospitalized Patients Based on the Perspective of Text Mining.

Objective: This study harnesses the power of text mining to quantitatively investigate the causative factors of falls in adult inpatients, offering valuable references and guidance for fall prevention measures within hospitals.

Methods: Employing KH Coder 3.0, a cutting-edge text mining software, we performed co-occurrence network analysis and text clustering on fall incident reports of 2,772 adult patients from a nursing quality control platform in a particular city in Jiangsu Province, spanning January 2017 to December 2022.

Evaluation of the value of Internet platform Enterprises in the digital economy by the big data cooperation asset valuation model.

With the innovation of information technology, the national industry has been adjusted and upgraded, and the development of the Internet industry has had a huge impact on economic development. The investment and financing of network enterprises and the merger and acquisition of network companies need to evaluate the value of network companies. In this regard, this paper evaluated the value of Internet platform enterprises under the digital economy based on the Big Data (BD) cooperation asset valuation model.

Recent advances in dynamic reconstruction of electrocatalysts for carbon dioxide reduction.

Electrocatalysts undergo structural evolution under operating electrochemical CO reduction reaction (CORR) conditions. This dynamic reconstruction correlates with variations in CORR activity, selectivity, and stability, posing challenges in catalyst design for electrochemical CORR. Despite increased research on the reconstruction behavior of CORR electrocatalysts, a comprehensive understanding of their dynamic structural evolution under reaction conditions is lacking.

Predicting the risk of primary Sjögren's syndrome with key N7-methylguanosine-related genes: A novel XGBoost model.

Objectives: N7-methylguanosine (m7G) plays a crucial role in mRNA metabolism and other biological processes. However, its regulators' function in Primary Sjögren's Syndrome (PSS) remains enigmatic.

Methods: We screened five key m7G-related genes across multiple datasets, leveraging statistical and machine learning computations.

Meta-analysis of Palliative Care on End-stage Quality of Life in Cancer Patients.

Objective: This study aimed to investigate the impact of palliative care on the quality of life, depressive state, and physical and psychological symptoms of patients with end-stage cancer.

Methods: A systematic literature search of PubMed, Embase, and Scopus databases was conducted for randomized controlled trials (RCTs) published from May 2000 to June 2023, focusing on the impact of palliative care on end-stage cancer patients. The search utilized terms such as "palliative care," "cancer/tumor/malignancy," "terminal/end-stage/advanced," to identify studies meeting our inclusion criteria.

Challenges of PICC placement via the popliteal vein under ultrasound guidance in a patient with severe burns: A case report.

Peripherally inserted central catheters are widely used in patients with extensive burns, with the guidelines recommending insertion through unburned skin. This case report describes a patient who was burned over 88% of their surface area and suffered severe inhalation injury. For him, the popliteal vein was the only vein on unburned skin available for catheter catheterization.

[Progressive myoclonic epilepsy: a retrospective study of newly-diagnosed adult patients from a single center].

Objective: To retrospectively analyze the clinical phenotype and pathogenic variants in patients with Progressive myoclonus epilepsy (PME).

Methods: Clinical data and results of genetic testing for 11 patients diagnosed with PME at the Department of Neurology, the First Affiliated Hospital of Zhejiang University School of Medicine from June 2017 to December 2022 were collected and analyzed.

Results: All of the patients, including 4 males and 7 females, had predominant action myoclonus.

Dynamic Reconstruction of Two-Dimensional Defective Bi Nanosheets for Efficient Electrocatalytic Urea Synthesis.

Catalyst surface dynamics drive the generation of active species for electrocatalytic reactions. Yet, the understanding of dominant site formation and reaction mechanisms is limited. In this study, we thoroughly investigate the dynamic reconstruction of two-dimensional defective Bi nanosheets from exfoliated BiSe nanosheets under electrochemical CO and nitrate (NO ) reduction conditions.

Coupling ultrafine TiO within pyridinic-N enriched porous carbon towards high-rate and long-life sodium ion capacitors.

Coupling TiO within N-doped porous carbon (NPC) is essential for enhancing its Na storage performance. However, the role of different N configurations in NPC in improving the electrochemical performance of TiO is currently unknown. In this study, melamine is deliberately incorporated as a pore-forming agent in the self-assembly process of metal organic framework precursors (NH-MIL-125(Ti)).

Clinical Experience of Prenatal Chromosomal Microarray Analysis in 6159 Ultrasonically Abnormal Fetuses.

A single-center retrospective study of G-band karyotyping and chromosomal microarray analysis (CMA) for the invasive prenatal diagnosis of 6159 fetuses with ultrasound abnormalities was conducted. This study aimed to investigate the incidence rates of chromosomal abnormalities and pregnancy outcomes and postpartum clinical manifestations by long-term follow-up and to explore the correlation between different types of prenatal ultrasound abnormalities and pathogenic chromosomal abnormalities. The overall incidence of pathogenic chromosomal aberrations in fetuses with ultrasound abnormalities was 7.

Programmable and Reversible Integrin-Mediated Cell Adhesion Reveals Hysteresis in Actin Kinetics that Alters Subsequent Mechanotransduction.

Dynamically evolving adhesions between cells and extracellular matrix (ECM) transmit time-varying signals that control cytoskeletal dynamics and cell fate. Dynamic cell adhesion and ECM stiffness regulate cellular mechanosensing cooperatively, but it has not previously been possible to characterize their individual effects because of challenges with controlling these factors independently. Therefore, a DNA-driven molecular system is developed wherein the integrin-binding ligand RGD can be reversibly presented and removed to achieve cyclic cell attachment/detachment on substrates of defined stiffness.