Building S-Scheme p-n Junction by the In Situ Sulfidation of Cu-TCPP Toward Boosted Photocatalytic Activity for CO Photoreduction and Sterilization.

In this work, an S-type p-n junction is designed and fabricated by in situ interfacial sulfidation of Cu-TCPP. Due to the combination of in situ derived CuS, the light absorption expanded to the full-solar-light spectrum, with expected thermal effect and exponentially increased electrical conductivity. The co-shared Cu atoms inspired intimate atomic-level contact and strong electron cooperation to formulate the high-speed electron/heat transfer channel.

Glucocorticoid Discontinuation in Patients with Rheumatoid Arthritis under Background of Chinese Medicine: Challenges and Potentials Coexist.

Objective: To evaluate the dynamic changes of glucocorticoid (GC) dose and the feasibility of GC discontinuation in rheumatoid arthritis (RA) patients under the background of Chinese medicine (CM).

Methods: This multicenter retrospective cohort study included 1,196 RA patients enrolled in the China Rheumatoid Arthritis Registry of Patients with Chinese Medicine (CERTAIN) from September 1, 2019 to December 4, 2023, who initiated GC therapy. Participants were divided into the Western medicine (WM) and integrative medicine (IM, combination of CM and WM) groups based on medication regimen.

The degree of esterification influences the bioactivity of pectic polysaccharides isolated from .

Pectic polysaccharides are the mainly bioactive components in (sweet tea) leaves. Nevertheless, owing to their diverse and complex chemical structures, the detailed structure-function relationships (SFR) of pectic polysaccharides from sweet tea (STP) are still unclear. Herein, the influence of STP's esterified degree on its diverse biological functions was uncovered.

Prospects of Ganoderma polysaccharides: Structural features, structure-function relationships, and quality evaluation.

Polysaccharides, the primary bioactive compounds found in Ganoderma, are responsible for a multitude of biological activities. The bioactivity of Ganoderma polysaccharides (GPs) closely correlates to their physicochemical properties. Consequently, the accurate characterization and quantification of GPs are essential for the quality control of these compounds.

Primary Study on Effect of Extraction Methods on the Properties and Activities of Polysaccharides from .

, a traditional Miao medicine with significant clinical potential, is rich in polysaccharides. Despite its importance, there is a scarcity of research on the structure and activities of these polysaccharides. In this study, polysaccharides from (GJPs) were extracted using various methods, including heated reflux extraction (HRE), acidic extraction (ACE), alkaline extraction (AAE), microwave-assisted extraction (MAE), enzymatic extraction (EAE), pressurized liquid extraction (PLE), and deep eutectic solvents extraction (DESE).

Telitacicept for refractory cystitis associated with severe systemic lupus erythematosus: A case report.

Background: Lupus cystitis, a severe complication of systemic lupus erythematosus (SLE), presents considerable treatment challenges.

Purpose: This case report describes the use of telitacicept in treating severe SLE with lupus cystitis.

Research Design: A single patient with lupus cystitis.

Bitterness quantification and simulated taste mechanism of theasinensin A from tea.

Theasinensin A is an important quality chemical component in tea, but its taste characteristics and the related mechanism are still unclear. The bitterness quantification and simulated taste mechanism of theasinensin A were researched. The results showed that theasinensin A was significantly correlated with the bitterness of tea.

Cu-MOFs based photocatalyst triggered antibacterial platform for wound healing: 2D/2D Schottky junction and DFT calculation.

Herein, we developed a multimodal antibacterial nanoplatform via synergism effect including knife-effect, photothermal, photocatalytic induced reactive oxygen species (ROS), and Cu inherent attribute. Typically, 0.8-TC/Cu-NS possesses higher photothermal property with the higher photothermal conversion efficiency of 24% and the moderate temperature up to 97 °C.

Low-temperature 3D-printed collagen/chitosan scaffolds loaded with exosomes derived from neural stem cells pretreated with insulin growth factor-1 enhance neural regeneration after traumatic brain injury.

There are various clinical treatments for traumatic brain injury, including surgery, drug therapy, and rehabilitation therapy; however, the therapeutic effects are limited. Scaffolds combined with exosomes represent a promising but challenging method for improving the repair of traumatic brain injury. In this study, we determined the ability of a novel 3D-printed collagen/chitosan scaffold loaded with exosomes derived from neural stem cells pretreated with insulin-like growth factor-1 (3D-CC-INExos) to improve traumatic brain injury repair and functional recovery after traumatic brain injury in rats.

Breast metastasis of cervical cancer: A case report and systematic literature review.

It has been reported that extramammary malignant tumors metastasize to the breast, but cervical cancer metastasis to the breast is very rare. At present, there are only dozens of reports about cervical cancer metastasis to breast in the world. It is difficult to distinguish between primary breast cancer and metastatic breast cancer.

China rheumatoid arthritis registry of patients with Chinese medicine (CERTAIN): Rationale, design, and baseline characteristics of the first 11,764 enrollees.

Background: Chinese medicine (CM) has become a popular interventional treatment for rheumatoid arthritis (RA). However, limited knowledge about general characteristics and long-term clinical outcomes hampers the development of CM for RA.

Purpose: The main objectives of the China Rheumatoid Arthritis Registry of Patients with Chinese Medicine (CERTAIN) were to describe the population of RA patients receiving CM treatment in multiple centers in China using different variables and compare these findings with internationally reported data.

Oxygen Vacancy Induced Boosted Visible-Light Driven Photocatalytic CO Reduction and Electrochemical Water Oxidation Over CuCo-ZIF@Fe O @CC Architecture.

Herein, the obtained Cu Co -ZIF@Fe O @CC-150 heterojunction (termed as Cu Co -ZFC-150) showed high hydrogen and oxygen evolution reaction (HER and OER) activities with low overpotential small Tafel slope. When employed to be the bifunctional anode and cathode, they only needed a cell voltage of 1.62 V.

Trilobatin rescues cognitive impairment of Alzheimer's disease by targeting HMGB1 through mediating SIRT3/SOD2 signaling pathway.

Alzheimer's disease (AD) is a progressive neurodegenerative disorder with cognitive impairment that currently is uncurable. Previous study shows that trilobatin (TLB), a naturally occurring food additive, exerts neuroprotective effect in experimental models of AD. In the present study we investigated the molecular mechanisms underlying the beneficial effect of TLB on experimental models of AD in vivo and in vitro.

Visible-light driven boosting electron-hole separation in CsPbBr QDs@2D Cu-TCPP heterojunction and the efficient photoreduction of CO.

CsPbBr quantum dots (CPB QDs) have great potential in photoreduction of CO to chemical fuels. However, the low charge transportation efficiency and chemical instability of CPB QDs presents a considerable challenge. Herein, we describe the electrostatic assemblies of negatively charged colloidal two dimensional (2D) Cu-Tetrakis(4-carboxyphenyl) porphyrins (Cu-TCPP) nanosheets and positively CPB QDs to construct the hydride heterojunction.

Neuroprotective Effect of Ultrasound Triggered Astaxanthin Release Nanoparticles on Early Brain Injury After Subarachnoid Hemorrhage.

Subarachnoid hemorrhage (SAH) is a fatal disease. Within 72 h of SAH, the intracranial blood-brain barrier (BBB) is destroyed, and the nerve cells have responses such as autophagy, apoptosis, and oxidative stress. Antioxidation is an essential treatment of SAH.

The covalent Coordination-driven BiS@NH-MIL-125(Ti)-SH heterojunction with boosting photocatalytic CO reduction and dye degradation performance.

Herein, the optional and controllable growth of BiS onto NH-MIL-125 via covalent conjunction strategy was reported. The experimental results demonstrate that the obtained heterojunction exhibits boosting photocatalytic reduction CO and organic dye degradation. The 18-BiS@NH-MIL-125-SH displays the highest yield of 12.