Decoupling adsorption affinity and regeneration barrier via dynamic electron redistribution in Fe-Zr metal-organic framework gels.

Amid global efforts toward low-energy gas purification, we present a bimetallic metal-organic framework gel (FeU-1) that overcomes the trade-off between adsorption capacity and regeneration energy. FeU-1 achieves a high toluene uptake of 975 mg/g (P/P = 0.97), while reducing the desorption activation energy from 169.

Exploring Anionic Redox Chemistry of Battery Cathodes with Resonant Inelastic X-Ray Scattering.

High-capacity and reversible cathodes are important for sustainable energy development. Layered oxides present promising options, achieving a high capacity while maintaining manageable production costs. Despite the redox activity of transition metal primarily contributes to the capacity, anionic redox offers additional potential, as evidenced by the subtle voltage plateau at high voltage.

Interface Engineering Assisted 3D Printing of Silicone Composites with Synergistically Optimized Impact Resistance and Electromagnetic Interference Shielding Effectiveness.

Silicone composites have been universally employed in smart devices, flexible electronics, and mechanical metamaterials. However, it remained challenging to develop 3D printable silicone composites with desirable mechanical and electrical properties. Here, an interface engineering strategy is reported, developing heterointerfacial silver-coated hollow glass microspheres (SHGMs), which are integrated with polydimethylsiloxane (PDMS) for 3D printing of impact-resistant, highly conductive, and mechanically robust SHGMs-PDMS (SHP) composites.

The effects of diacylglycerol edible oil intervention in patients with chronic metabolic syndrome combined with asymptomatic hyperuricemia: study protocol for a multicenter, prospective, double-blind, randomized controlled trial.

Background: The aim of this study is to evaluate the efficacy and safety of diacylglycerol (DAG) edible oil intervention in patients with chronic metabolic syndrome complicated by asymptomatic hyperuricemia through a multicenter, prospective, double-blind, randomized controlled clinical trial.

Methods: A multicenter, double-blind, and randomized controlled trial involving 176 patients was designed. All patients with chronic metabolic syndrome complicated by asymptomatic hyperuricemia who meet inclusion and exclusion criteria will be included in the study and will be randomized to either group A or group B.

Dewetting of thin polymer films reveals non-equilibrium conformational difference between substrate and air sides.

The anomalous dynamics of thin polymer films, often attributed to geometrical confinement and interfacial interaction, have aroused considerable interest, particularly with regard to the inherent and processing-induced chain conformation changes. Here, the capillary peeling method is employed to obtain reattached thin polystyrene films with either the substrate or the air side beneath. Compared to traditional dewetting experiments solely conducted on the substrate side of as-cast films, the difference in dewetting behavior between the two sides of films is demonstrated, with the air side showing a faster dewetting velocity in the early stage and a larger apparent residual stress.

PIEZO1 mediates matrix stiffness-induced tumor progression in kidney renal clear cell carcinoma by activating the Ca/Calpain/YAP pathway.

Objective: The significance of physical factors in the onset and progression of tumors has been increasingly substantiated by a multitude of studies. The extracellular matrix, a pivotal component of the tumor microenvironment, has been the subject of extensive investigation in connection with the advancement of KIRC (Kidney Renal Clear Cell Carcinoma) in recent years. PIEZO1, a mechanosensitive ion channel, has been recognized as a modulator of diverse physiological processes.

A compact ion source combining electron-impact and thermal ionization for multiple-reflection time-of-flight mass spectrometry.

A compact ion source combining electron impact and thermal ionization has been developed and commissioned in two Multiple-Reflection Time-Of-Flight Mass Spectrometer (MR-TOF-MS) setups at the Fragment Separator Ion Catcher at the GSI Helmholtz Centre for Heavy Ion Research, Darmstadt, Germany, and at TRIUMF's Ion Trap for Atomic and Nuclear science at TRIUMF Canada's particle accelerator center, Vancouver, Canada. The ion source is notable for its compact dimensions of 50 mm in height and 68 mm in diameter. The ion source is currently in daily operation at both facilities.

Research Progress of Cyanine-Based Near-Infrared Fluorescent Probes for Biological Application.

Cyanine-based near-infrared (NIR) fluorescent probes have played vital roles in biological application due to their low interference from background fluorescence, deep tissue penetration, high sensitivity, and minimal photodamage to biological samples. They are widely utilized in molecular recognition, medical diagnosis, biomolecular detection, and biological imaging. Herein, we provide a review of recent advancements in cyanine-based NIR fluorescent probes for the detection of pH, cells, tumor as well as their application in photothermal therapy (PTT) and photodynamic therapy (PDT).

Central memory CD4+ T cells play a protective role against immune checkpoint inhibitor-associated myocarditis.

Aims: The widespread use of immune checkpoint inhibitors (ICIs) has demonstrated significant survival benefits for cancer patients and also carries the risk of immune-related adverse events. ICI-associated myocarditis is a rare and serious adverse event with a high mortality rate. Here, we explored the mechanism underlying ICI-associated myocarditis.

Farmland pest recognition based on Cascade RCNN Combined with Swin-Transformer.

Agricultural pests and diseases pose major losses to agricultural productivity, leading to significant economic losses and food safety risks. However, accurately identifying and controlling these pests is still very challenging due to the scarcity of labeling data for agricultural pests and the wide variety of pest species with different morphologies. To this end, we propose a two-stage target detection method that combines Cascade RCNN and Swin Transformer models.

Improving the removal efficiency of oxygenated volatile organic compounds by defective UiO-66 regulated with water.

The purification of oxygenated volatile organic compounds VOCs (OVOCs), important precursors of ozone and particulate matters, has triggered intensive research interests. UiO-66 with high photocatalytic activity have shown great potential. However, the lack of active sites severely limited the trapping and degradation of OVOCs.

Large-Scale Fabrication of Freestanding Polymer Ultrathin Porous Membranes for Transparent Transwell Coculture Systems.

Advancements in cell coculture systems with porous membranes have facilitated the simulation of human-like microenvironments for diverse biomedical applications. However, conventional Transwell membranes face limitations in low porosity (ca. 6%) and optical opacity due to their large thickness (ca.

The association between leisure activity and mental health in the older adults in China: amazing Guangchangwu.

Objective: Since the mental health of older adult is an important topic in the aging society, the main purpose of this study is to understand the mental health status of the older adult in China under different conditions. More importantly, although people generally believe that leisure activities can improve mental health, the impact of these activities on older adult has not yet been fully discussed. Hence, this study further explores that what kind of leisure activity is associated with mental health of the older adult given different conditions.

Heating-induced adsorption promoting the efficient removal of toluene by the metal-organic framework UiO-66 (Zr) under visible light.

The removal of indoor/outdoor toluene by photocatalysis has drawn much attention due to its low energy consumption and easy availability. However, light inevitably generates heat, and pollutants desorb from catalysts as the temperature rises, which is not beneficial to degradation. Contrast to the frequently occurred phenomena, we firstly found that the adsorption capacity of UiO-66 (Zr) on toluene increased with increasing temperature as adsorption isotherms and in-situ Fourier transform infrared spectra (in-situ FTIR) showed.

CCT6A dysregulation in surgical prostate cancer patients: association with disease features, treatment information, and prognosis.

Objective: Chaperonin-containing tailless complex polypeptide 1 subunit 6A (CCT6A) involves several solid cancers' development and progression, while its clinical utility in prostate cancer management is rarely revealed. Consequently, the present study intended to investigate the linkage of CCT6A with disease features, treatment information, and prognosis of surgical prostate cancer patients.

Methods: CCT6A in 220 surgical prostate cancer patients was determined via immunohistochemistry.

Skeletal muscle alterations indicate poor prognosis in cirrhotic patients: a multicenter cohort study in China.

Introduction: We aimed to determine the diagnostic criteria of myosteatosis in a Chinese population and investigate the effect of skeletal muscle abnormalities on the outcomes of cirrhotic patients.

Methods: Totally 911 volunteers were recruited to determine the diagnostic criteria and impact factors of myosteatosis, and 480 cirrhotic patients were enrolled to verify the value of muscle alterations for prognosis prediction and establish new noninvasive prognostic strategies.

Results: Multivariate analysis showed age, sex, weight, waist circumference, and biceps circumference had a remarkable influence on the L3 skeletal muscle density (L3-SMD).

Serum vitamin C levels and risk of non-alcoholic fatty liver disease: results from a cross-sectional study and Mendelian randomization analysis.

Background And Aims: Vitamin C, as an antioxidant, may play a role in the treatment of NAFLD. This research aimed to investigate the association of serum vitamin C levels with the risk of NAFLD and to further examine the causal relationship by Mendelian randomization (MR) method.

Methods: The cross-sectional study selected 5,578 participants of the National Health and Nutrition Examination Survey (NHANES), 2005-2006 and 2017-2018.

Efficacy and safety of abrocitinib for moderate-to-severe atopic dermatitis in adolescents and adults: Meta-analysis.

This study aims to investigate the safety and efficacy of abrocitinib in treating moderate-to-severe AD in adolescents and adults. Pubmed, Cochrane, Embase, and Web of science data base were searched from inception to 9 August 2022. All randomized controlled trials (RCTs) evaluating the efficacy and safety of abrocitinib in moderate to severe AD were included in the meta-analysis.

Metagenomic analysis of the relationship between the microorganisms and the volatiles' development in the wines during spontaneous fermentation from the eastern foothills of the Ningxia Helan mountains in China.

Background: The natural fermentation of multispecies microbial communities is responsible for unique flavors of winery regions of the eastern foothills of the Ningxia Helan Mountains in China. However, the participation of different microorganisms in the metabolic network for the development of important flavor substances is not clearly defined. Microbial population and diversity on different fermentation phases of Ningxia wine were analyzed by metagenomic sequencing approach.

An Integrated Plasma-Photocatalytic System for Upcycling of Polyolefin Plastics.

Nondegradable polyolefin plastics, which account for >60 % of total plastic waste, trigger severe global concerns and thus demand effective management technologies. However, owing to the chemical inertness of non-polar C-C backbones in the polyolefin structure, efficient upcycling of polyolefin plastics under ambient conditions remains a great challenge. This study introduces an integrated plasma-photocatalytic technology, coupling plasma treatment with solar-driven reforming under mild conditions, for the efficient upcycling of polyolefin plastics into value-added hydrogen and gaseous fuels.

The effects of biogenic amines in Chinese Huangjiu on the behavior of mice and hangover headache-related indices.

Huangjiu (Chinese rice wine) is a popular and traditional alcoholic beverage in China; however, the consumption of Huangjiu readily results in hangover symptoms. The aim of this study was to identify the main components associated with behavioral inhibition, headache, and the relevant mechanisms by using a mice hangover model. The results of an open-field experiment revealed that the key biogenic amine associated with mice behavior was histamine, which inhibited the behavior activity of mice in a dose-dependent manner.

The gelatin-based liquid marbles for cell cryopreservation.

As an alternative and a straightforward cryopreservation biotechnological tool, liquid marble provides a promising cryopreservation approach. Currently, effective cell preservation mainly based on the addition of dimethyl sulfoxide (DMSO) and fetal bovine serum (FBS). As state-of-the-art cryoprotectant (CPA), DMSO, has intrinsic toxicity, which is the bottleneck of its widespread application.

Can online health information sources really improve patient satisfaction?

Internet information has become the main way for individuals to obtain health information. The purpose of this paper is to explore the role online information sources play in health decision-making. Specifically, we investigated the relationship between online information sources and patient satisfaction, as well as their moderating effects as compared to those of other information sources.