Design of Event-Triggered H Fuzzy Integral Controller for Nonlinear Singularly Perturbed Systems With Parametric Uncertainties.

In this article, we proposed a fuzzy controller for nonlinear two-time-scale systems with uncertain system parameters. The designed controller is implemented using integral control and event-triggered strategy to deal with the singularly perturbed system (SPS), which typically operates on both the fast and slow dynamics simultaneously because of the small value parameter, namely, the parasitic parameter ε. Two main challenges of this work are the instability of SPS-caused by the presence of parasitic parameter, the parameter uncertainties and external disturbances-and the data transmission load between the system and the controller.

Efficient solar-driven tandem catalysis for biomass valorization: selective CC bond cleavage to synthesize xylitol.

The Liquid-Sunshine presents a transformative approach for converting biomass into high-value platform chemicals (HPCs). However, conventional photorefineries suffer from low efficiency and excessive byproduct formation due to the inherent incompatibility between biomass and photocatalysts. Herein, we introduce an innovative tandem oxygen-reforming-photocatalysis (TORP) strategy, which first selectively reforms biomass functional groups before driving photocatalytic CC bond cleavage to produce HPCs.

Characteristic volume, texture, and functional connectivity alterations in hypothalamic subunits of adult primary hypothyroidism: a multiparametric MRI analysis.

Purpose: Primary hypothyroidism arises from insufficient production of thyroid hormone (TH), characterized by serum thyroid stimulating hormone levels above the reference range (0.35-4.94 mIU/L) and serum-free thyroxine (FT4) levels normal/reduced the reference value (9.

Underlying mechanisms of Traditional Chinese Medicine in treating metabolic dysfunction-associated steatohepatitis: evidences from preclinical and clinical studies.

Ethnopharmacological Relevance: Traditional Chinese Medicine (TCM) has been employed for thousands of years as an effective treatment for liver diseases. In recent years, it has gained widespread use in the management of metabolic dysfunction-associated steatohepatitis (MASH).

Aim Of The Study: This article reviews the application of TCM in treating MASH, examining its pathogenesis, current treatment strategies, and preclinical (in vitro and in vivo) and clinical studies of TCM on MASH, with the aim to provide TCM-based solutions for MASH treatment.

Drying characteristics and quality enhancement of Moringa oleifera seeds through Ultrasound and Microwave-Assisted germination combined with infrared vacuum drying.

Moringa oleifera (MO), is greatly appreciated for its high nutritional profile. Germination is an efficient technique to enhance the quality profile of seeds. This study examined the effects of germination and various pre-treatments on MO seeds.

Learning Distance Constrained Transformation for Video Tracking in Car-Following.

Recent advances in video tracking with discriminative correlation filters leverage diverse observation models. However, fusing hand-crafted and deep convolutional neural network representations equivalently would overly constrain resolution conditions for template matching, leading to peak response slippage and jittery neighboring search processes, especially problematic in autonomous driving scenarios. This article addresses the inference conservatism issue in multitype feature tracking.

Elevated Histone Lactylation Mediates Ferroptosis Resistance in Endometriosis Through the METTL3-Regulated HIF1A/HMOX1 Signaling Pathway.

Endometriosis (EMs) is a chronic gynecologic condition characterized by the growth of endometrial stromal and glandular tissue outside the uterine cavity of unknown etiology. Currently, ferroptosis resistance, increased glycolysis, and increased lactate production are identified in EMs. Histone lactylation is a lactate-derived posttranslational modification that is recognized primarily for its role in epigenetic regulation.

Pelargonidin-3--galactoside Alleviates Acute Lung Injury Induced by by Targeting CD38-Mediated Pyroptosis.

Antibiotic resistance has amplified the threat of bacterial-induced acute lung injury (ALI) to human health. In the quest for novel therapeutic strategies, natural products have shown promise in mitigating the severity of this condition. In this study, we explored the protective effects of pelargonidin-3--galactoside (Pg3gal) on (KP)-induced ALI and its underlying mechanisms.

Space weathering on the lunar nearside and farside constrained from Si isotopes.

Over long timescales, space weathering processes can modify the compositions of surface materials on the Moon. To assess the effects of space weathering of lunar soils, we study Si isotopes of Chang'E-5 (CE-5) and Chang'E-6 (CE-6) returned samples, and lunar meteorites. Here we show that both bulk soils from CE-5 and CE-6 exhibit heavier Si isotopic compositions than the basalt clasts within the soils and lunar meteorites, indicating that the space weathering obviously increase δSi of lunar soils.

MARCH8 promotes the proteasomal degradation of foot-and-mouth disease virus VP1, VP2, and VP3 to negatively regulate viral replication.

The host cell membrane-associated RING-CH8 protein (MARCH8) functions as an antiviral host factor by targeting viral envelope glycoproteins. Foot-and-mouth disease virus (FMDV) is a non-enveloped, positive-sense, single-stranded RNA virus. The potential impact of MARCH8 on FMDV replication remains uncertain.

Cortical Surface Spatial Analysis Reveals Altered Brain Functional Network Topology in T2DM With Mild Cognitive Impairment.

Objective: Approximately 45.0% of patients who have type 2 diabetes mellitus (T2DM) exhibit mild cognitive impairment (MCI). However, the specific alternations in T2DM with MCI (T2DM-MCI)-related brain functional networks (BFN) remain unclear.

Observer-Based Periodic Event-Triggered Adaptive Fuzzy Control for Networked Nonlinear Systems.

This article addresses the periodic event-triggered adaptive output feedback control problem for networked system with unknown nonlinear dynamics. Based on the output-dependent periodic event-triggered mechanism (PETM), a nonlinear observer is designed to estimate system states, where the fuzzy-logic systems-based approximation method and adaptive technique are employed to approximate and compensate for uncertainties. To enhance resource utilization efficiency in communication channels, a new observer and parameter estimators-dependent parallel PETM is proposed to schedule intermittent packet transmission.

Caffeic acid and chlorogenic acid mediate the ADPN-AMPK-PPARα pathway to improve fatty liver and production performance in laying hens.

Background: Caffeic acid (CA) and its derivative, chlorogenic acid (CGA), have shown promise in preventing and alleviating fatty liver disease. CA, compared to CGA, has much lower production costs and higher bioavailability, making it a potentially superior feed additive. However, the efficacy, mechanistic differences, and comparative impacts of CA and CGA on fatty liver disease in laying hens remain unclear.

Dietary effect of Galega orientalis Lam. flavonoid extract on broilers' growth performance, antioxidant capacity, immune function, and bone metabolism.

This study aimed to evaluate the impact of dietary Galega orientalis Lam. flavonoid extract (GOLFE) on production performance, biological markers, and bone health of white-feather broilers. A total of 540 one-day-old Cobb broilers were randomly assigned to six dietary groups: a negative control group (without additives; G0), four nutritional additive groups supplemented with GOLFE (G1:200 mg, G2: 400 mg, G3:800 mg, and G4:1600 mg), and a positive control group (supplemented with chlortetracycline; G5:100 mg).

Supramolecular discrimination and diagnosis-guided treatment of intracellular bacteria.

Pathogenic intracellular bacteria pose a significant threat to global public health due to the barriers presented by host cells hindering the timely detection of hidden bacteria and the effective delivery of therapeutic agents. To address these challenges, we propose a tandem diagnosis-guided treatment paradigm. A supramolecular sensor array is developed for simple, rapid, accurate, and high-throughput identification of intracellular bacteria.

Less Is More: Donor Engineering of a Stable Molecular Dye for Bioimaging in the NIR-IIb Window.

Fluorescence molecular imaging aims to enhance clarity in the region of interest, particularly in the near-infrared IIb window (NIR-IIb, 1500-1700 nm). To achieve this, we developed a novel small-molecule dye, named , based on classic cyanine dyes (heptamethine or pentamethine is essential for wavelengths beyond 1000 nm). By reducing excessive polymethine to a single methine and disrupting symmetry to form an asymmetric donor-π-acceptor (D-π-A) architecture, we enhanced the donor's electron-donating capability, yielding emission at 1088 nm.

Development and feasibility of an echocardiography-guided tip location program for central venous catheter implantation.

This is a prospective observational study designed to develop an echocardiography-guided tip location program for central venous catheter (CVC) implantation, and to assess the feasibility and the accuracy of the program. First, a multidisciplinary expert committee designed an echocardiography-guided tip location program; then, a pilot prospective observational study was conducted to assess the feasibility of the program in a vascular access clinic in a tertiary hospital. A total of 186 patients participated in the study.

Preparation and application of porcine broadly neutralizing monoclonal antibodies in an immunoassay for efficiently detecting neutralizing antibodies against foot-and-mouth disease virus serotype O.

Neutralizing antibodies provide vital protection against foot-and-mouth disease virus (FMDV). The virus neutralization test (VNT) is a gold standard method for the detection of neutralizing antibodies. However, its application is limited due to the requirement for live virus and unsuitability for large-scale serological surveillance.

Semi-rational design and modification of phosphoketolase to improve the yield of tyrosol in .

Tyrosol is an important component of pharmaceuticals, nutraceuticals, and cosmetics, and their biosynthetic pathways are currently a hot research topic. d-Erythrose 4-phosphate is a key precursor for the biosynthesis of tyrosol in . Hence, the flux of d-Erythrose 4-phosphate determined the yield of tyrosol synthesis.

Enhanced multistress tolerance of with the sugar transporter-like protein Stl1 mutation in the presence of glycerol.

Unlabelled: During microbial industrial production, microorganisms often face diverse stressors, including organic solvents, high salinity, and high sugar levels. Enhancing microorganism tolerance to such stresses is crucial for producing high-value-added products. Previous studies on the mechanisms of 2-phenylethanol (2-PE) tolerance in revealed a potential connection between the sugar transporter-like protein (Stl1) mutation (F427L) and increased tolerance to high sugar and salt stress, suggesting a broader role in multistress tolerance.

Engineering Asymmetric Bimetallic CoM (M = Ni, Fe, Mn, Cu) Nanoparticles Encapsulated in Freestanding Wood-Derived Carbon Electrodes for Enhanced ORR Kinetics in Zinc-Air Batteries.

The electrochemical reduction of oxygen is pivotal for advancing emerging energy technologies. Precise control over morphology and electronic structure is essential for enhancing catalytic activity and stability in the oxygen reduction reaction (ORR). In this study, a freestanding carbon electrode is developed by in-situ growth of carbon nanotube (CNT)-encapsulated bimetallic CoM (M = Ni, Fe, Mn, Cu) nanoparticles (NPs) within a hierarchical carbonized wood matrix (CoM@NWCC).

Analysis on Degradation Mechanism and Product Recycle of Ex-service Wind Turbine Blades by Hydrothermal Liquefaction.

The recycling of ex-service wind turbine blades (EWTBs) presents a significant challenge for the future. Hydrothermal liquefaction (HTL) has emerged as a promising approach for the recovery of resins and glass fibers (GFs) from EWTBs. This study offers a comprehensive analysis of the separation mechanisms and product characteristics under the catalytic effect of an acidic medium during the HTL tests.

Sustainably transforming biomass into advanced carbon materials for solid-state supercapacitors: a review.

Biomass-derived carbon materials (BDCMs) are widely considered as promising and practical candidates for electrode materials of solid-state supercapacitors (SSCs), due to their low cost, good chemical and mechanical stabilities, excellent electrical conductivity, and high deployment feasibility. Numerous investigations have recently been conducted for sustainably transforming biomass into electrode materials with high electrochemical performance in SSCs, even guided by data-driven approaches. Therefore, this review addresses conventional and emerging synthesis routes for BDCM-based electrode materials and discusses recent advances in energy storage mechanisms and electrochemical performance enhancement of BDCMs for SSCs, improving electrode preparation and performance optimization of BDCMs in a practical and efficient manner.