Multiomics analysis of gibberellin involved in far-red light-regulated internode elongation in cucumber seedlings.

GA participates in FR light-induced internode elongation of cucumber by regulating the expression of genes/proteins related to aquaporins, expansins, cell wall biosynthesis, hormone metabolism, and signal transduction. This study investigated the effects of the interaction between far-red (FR) light and gibberellin (GA) on the internode elongation of cucumber (Cucumis sativus L. 'Zhongnong No.

The Role of in the Pathogenicity of Avian Pathogenic .

The genotoxin colibactin, a complex secondary metabolite, targets eukaryotic cell cycle machinery and contributes to neonatal sepsis and meningitis. Avian pathogenic (APEC) XM, which produces this genotoxin, is an agent of poultry diseases with zoonotic potential. In this study, we confirmed that was necessary for the APEC XM strain to produce colibactin, but it did not affect the growth, adhesion, or invasion of cells.

Dynamic interface catalysis and carbon dioxide reduction of liquid metals.

Liquid metal (LM) catalysis has been demonstrated to have obvious potential in the fields of energy conversion and environmental catalysis due to its unique dynamic interface, adjustable electronic structure and regenerative ability of active sites. Compared with traditional solid-state catalysts, the atomic-level degrees of freedom and fluidity of typical gallium-based LMs exhibit advantages such as anti-poisoning, interface self-repair, and dynamic regulation of reaction pathways. Based on the fundamental characteristics and mechanisms of LM catalysis, this work systematically expounds the phase structure regulation corresponding to achieving low-temperature fluidity.

Fining Crystal Facet and Oxygen Vacancy Engineering of Bifunctional BiOBr Facilitates Excellent Photocatalytic Hydrogen Evolution and Phenol Hydroxylation.

The most cost-effective and environmentally benign method of producing hydrogen fuel from water is solar-driven hydrogen production, using efficient photocatalysts with low-energy photons. Engineering such a photocatalyst remains highly challenging. In this work, BiOBr(001) and BiOBr(010) nanosheets were synthesized using the hydrothermal method.

Improving long-term stability of optoelectronic oscillators using genetic algorithm-optimized dual-parameter control.

We demonstrate a dual-parameter control strategy that simultaneously modulates laser temperature and current to enhance the long-term frequency stability of optoelectronic oscillators (OEOs). A simulation environment was developed to model the frequency control dynamics, within which proportional-integral-derivative (PID) parameters were optimized using a genetic algorithm before hardware development. Experimental results show that the proposed approach expands the effective compensation range to 2.

In situ unravelling surface plasmon resonance subject-object role of BiVO@Ag in photocatalytic water splitting.

Surface plasmon resonance (SPR) of noble metal particles has been recognized to play a significant role in photocatalysis. We designed the BiVO@Ag system by photo-deposition to prove the special role of Ag nanoparticles (NPs) in promoting water splitting. The BiVO@Ag considerably increases light absorption by the SPR effect of Ag NPs.

Modification of Spanish Mackerel () Surimi Gels by Three Anionic Polysaccharides.

This study investigated the gel performance of Spanish mackerel surimi gels (SMSGs) modified by three anionic polysaccharides: κ-carrageenan (KC), ι-carrageenan (IC), and gellan gum (GG). By incorporating polysaccharides, SMSGs showed a 24.9-103.

Differential phenological responses of permanently vs. intermittently inundated wetlands to climate warming in Northeast China.

Global warming tends to alter vegetation phenology and prolong the growing season. However, the influence of permanent and intermittent inundation on wetland vegetation responses to climate warming remains uncertain. In this study, we explored the phenological dynamics of wetland vegetation-specifically the start of the growing season (SOS) and end of the growing season (EOS)-across Northeast China from 2001 to 2020 using satellite-derived normalized difference vegetation index (NDVI) data.

Porous Core-Shell CoO@CuCoO Derived from Metal-Organic Frameworks as the Cathode Material for Lithium-Oxygen Batteries.

Nonaqueous lithium-oxygen (Li-O) batteries, owing to their ultrahigh theoretical energy density, have attracted extensive research attention. However, the commercialization of these systems is limited by the sluggish kinetics, necessitating advanced catalyst design. Herein, ZIF-67 is utilized as a self-sacrificial template to fabricate dual spinel CoO@CuCoO with a porous core-shell structure via a simple solvothermal-calcination process, which is designed as a highly efficient cathode electrocatalyst for the Li-O battery.

Gel properties of grass carp (Ctenopharyngodon idella) surimi treated by different calcium salts as sodium chloride substitutes.

This study investigated the effect of various calcium salts [calcium chloride (CaCl), calcium sulfate (CaSO), calcium β-hydroxy-β-methylbutyrate (CaHMB), calcium acetate (CaAc)] on gel properties of grass carp (Ctenopharyngodon idella) surimi gels (GCSGs). CaHMB and CaAc obviously improved the textural properties of GCSGs by 31.3 %-55.

Experimental validation, molecular docking, proteomic analysis and network pharmacology reveal Morroniside promoting neurogenesis and improving cognitive impairment via Notch1/Hes1 pathway in intracerebroventricular-streptozotocin mice.

Ethnopharmacology Relevance: Alzheimer's disease (AD) is a widely occurred neurodegenerative disease and Notch1/Hes1 pathway based neural stem cell (NSC) proliferation and neurogenesis are very crucial to restore cognitive ability. Cornus officinalis Sieb. et Zucc, a famous traditional Chinese herb remedy was widely used to tonify kidney and essence to ameliorate AD symptoms.

Emerging cell-free DNA scavenging biomaterials for inflammatory diseases: From mechanisms to therapies.

Cell free deoxyribonucleic acids (cfDNA), fragments of DNA released by cell death or active secretion, has emerged as an inflammatory mediator closely associated with many inflammatory diseases. cfDNA-scavenging biomaterials could effectively capture or degrade cfDNA in body fluids, avoiding the activation of cellular innate and adaptive immune responses and thus inhibiting the development of inflammatory process. The development of cfDNA-scavenging biomaterials is in its infancy yet fast-growing.

Hydrogen Therapy and Lipopolysaccharide Trapping with MgB2@Inulin Gel for Reversing Colitis and Its Associated Psychiatric Complications via the Gut-Brain Axis.

Individuals diagnosed with inflammatory bowel disease (IBD) frequently encounter dysbiosis of the intestinal microbiota and are predisposed to psychiatric comorbidities, such as depression and anxiety. The development of oral therapeutics that concurrently attenuate intestinal inflammation, modulate gut microbiota, and ameliorate psychiatric symptoms is imperative for effective IBD management. This study introduced an orally administered Inulin gel incorporating magnesium diboride nanosheets (MgB@Inulin gel).

The role of green credit in energy resilience: A quasi-natural experiment from China.

Green credit policy is an important practice of financial regulation, and its possible effect on energy resilience cannot be ignored. This article adopts theoretical derivation and empirical strategies to study the effect and mechanism of green credit on energy resilience. The promulgation of "green credit guidelines" is used as a quasinatural experiment, and the findings indicate that green credit can significantly improve energy resilience.

Lateral connection convolutional neural networks for obstructive sleep apnea hypopnea classification.

Despite the successful operation of convolutional neural networks (CNN) with obstructive sleep apnea hypopnea (OSAHS) classification, the interpretability of these models is poor. The limited capacity to understand models hinders the comprehension of end-users, including sleep specialists. At the same time, these models need labeled data; however, this is a time-consuming, labor-intensive, and costly process.

Large Yellow Croaker Roe Protein Isolates/Gellan Gum Hydrogels Improve the Alleviating Effect of Curcumin on DSS-Induced Colitis.

In this study, large yellow croaker () protein isolates/gellan gum (PG) binary hydrogels with dense microstructure were used for embedding and delivery curcumin (Cur). The colitis-relieving effects of PG-Cur were further investigated using the dextran sulfate sodium (DSS)-induced ulcerative colitis (UC) mouse model. Following PG-Cur treatment, weight loss, diarrhea, and shortening of the colon were significantly alleviated.

Whirlwind Acoustic Vortex-Regulated Intelligent Microbots for Enhanced Uniform Drug Bioaccumulation to Boost Systemic Immunity Against Large Tumors.

Engineered bacteria as intelligent microbots preferentially targeting and colonizing tumors have overcome the poor delivery efficacy of nanomedicines toward large hypoxic tumors. In this study, Escherichia coli (E.coli) filled with gas vesicles is modified with drugs-loaded liposomes via amide condensation to achieve synergistic sono-chemotherapy.

Improvement of anti-inflammatory efficacy of apigenin by shrimp (Penaeus vannamei) powder/κ-carrageenan hydrogel in dextran sulfate sodium-induced colitis.

Shrimp (Penaeus vannamei) powder/κ-carrageenan (SP/KC) hydrogel was used to improve the anti-inflammatory efficacy of apigenin (API) with elastic gel properties and dense honeycomb microstructures. Ulcerative colitis (UC) mice were gavaged with API and SP/KC/API, respectively, to evaluate the effectiveness of SP/KC. Compared with API group, the weight loss and colon shortening of UC mice in the SP/KC/API group were alleviated from 35.

EFTUD2 Regulates Cortical Morphogenesis via Modulation of Caspase-3 and Aifm1 Splicing Pathways.

Elongation Factor Tu GTP-Binding Domain Containing 2 (EFTUD2), a core spliceosomal GTPase associated with Mandibulofacial Dysostosis with Microcephaly (MFDM), plays a mechanistically undefined role in cerebral development. To investigate its pathophysiological contributions, murine models are generated through conditional Eftud2 ablation and in utero electroporation of human pathogenic EFTUD2 variants into cortical neural stem cells (NSCs). Embryonic NSC-specific Eftud2 knockout resulted in cortical disorganization and microcephaly, while pathogenic variants led to significant neuronal loss.

Modification of functionalities and in vitro digestibility of clam Mactra chinensis powder upon ultrasound treatment.

Background: Abundant protein and amino acids have been found in clam Mactra chinensis powder (MCp), while the functionalities and in vitro digestibility of MCp are not clear. Meanwhile, ultrasound treatment is wildly used in modification of proteins. In this study, ultrasound was used to modify MCp at amplitudes from 30% to 90%, and the functionalities and in vitro digestibility of MCp upon ultrasound treatment were evaluated.

[Diagnosis and treatment of vocal cord leukoplakia].

As narrow band imaging（NBI） technology and research for vocal fold leukoplakia have advanced, the diagnostic and therapeutic paradigms for this condition have evolved significantly. This paper provides insight into the challenges of clinical management of vocal fold leukoplakia, drawing on our empirical findings to clarify the etiology, differential diagnosis, pathological grading, morphological characteristics, and recent therapeutic developments of this condition.

Optimization and evaluation of an experimental subarachnoid hemorrhage model in mice.

Subarachnoid hemorrhage (SAH) occurs when blood enters the subarachnoid space, typically due to aneurysm rupture, triggering complex pathophysiological processes. A reliable animal model is crucial for simulating SAH and investigating mechanisms of brain white matter injury. SAH was induced in C57BL/6J mice using an intraluminal perforation technique.

van der Waals Complementary Barrier Infrared Detector.

Infrared photodetectors have garnered significant attention in modern optoelectronics due to various applications. However, uncooled infrared photodetectors based on narrow-bandgap materials suffer from high dark current arising from thermal carrier excitation, posing a major challenge in achieving state-of-the-art infrared photodetectors with a blackbody response. In this work, we propose a van der Waals (vdW) complementary barrier infrared detector (CBD), which is composed of an electron barrier from gold/black phosphorus (Au/BP) Schottky contact and a hole barrier from molybdenum disulfide (MoS).

Brain circuits that regulate social behavior.

Social interactions are essential for the survival of individuals and the reproduction of populations. Social stressors, such as social defeat and isolation, can lead to emotional disorders and cognitive impairments. Furthermore, dysfunctional social behaviors are hallmark symptoms of various neuropsychiatric disorders, including autism spectrum disorder (ASD) and post-traumatic stress disorder (PTSD).