Phosphorylation of Wild Soybean (Glycine soja) Splicing Factor GsSCL30a by GsSnRK1 Regulates Soybean Tolerance to Alkali Stress.

Pre-mRNA splicing is a fundamental process in plant gene expression, and the resulting transcripts may play significant roles in plant development and responses to environmental changes. Wild soybean (Glycine soja), as a close relative of cultivated soybean (Glycine max), has excellent traits such as alkali tolerance and is an ideal material for mining stress-resistant genes. Previous phosphoproteomic analysis identified SR protein GsSCL30a as a potential phosphorylation substrate of GsSnRK1 kinase.

Exploring the Biodiversity and Antibacterial Potential of the Culturable Soil Fungi in Nyingchi, Tibet.

The Qinghai-Tibet Plateau, known as "the third pole" of the Earth, boasts unique climatic conditions with abundant sunlight, low temperature, and significant annual temperature variations, nurturing a diverse array of soil microorganisms with rich metabolic products. In this study, 132 fungal isolates were isolated and identified from the soil samples collected in Nyingchi, Tibet, belonging to 32 genera and 59 species, while Ascomycota, Mucoromycota, and Basidiomycota accounted for 91.7%, 7.

Bioactive Angucyclines/Angucyclinones Discovered from 1965 to 2023.

Angucyclines/angucyclinones, a class of polyketides with diverse chemical structures, display various bioactivities including antibacterial or antifungal, anticancer, anti-neuroinflammatory, and anti-α-glucosidase activities. Marine and terrestrial microorganisms have made significant contributions to the discovery of bioactive angucyclines/angucyclinones. This review covers 283 bioactive angucyclines/angucyclinones discovered from 1965 to 2023, and the emphasis is on the biological origins, chemical structures, and biological activities of these interesting natural products.

Unveiling the economic potential of sports industry in China: A data driven analysis.

The article explains the economic dynamics of the sports industry with adoption of deep learning algorithms and data mining methodology. Despite outstanding improvements in research of sports industry, a significant gap prevails with regard to proper quantification of economic benefits of this industry. Therefore, the current research is an attempt to filling this gap by proposing a specific economic model for the sports sector.

Learning-based real-time imaging through dynamic scattering media.

Imaging through dynamic scattering media is one of the most challenging yet fascinating problems in optics, with applications spanning from biological detection to remote sensing. In this study, we propose a comprehensive learning-based technique that facilitates real-time, non-invasive, incoherent imaging of real-world objects through dense and dynamic scattering media. We conduct extensive experiments, demonstrating the capability of our technique to see through turbid water and natural fog.

Passive imaging through inhomogeneous scattering media.

According to the atmospheric scattering model (ASM), the object signal's attenuation diminishes exponentially as the imaging distance increases. This imposes limitations on ASM-based methods in situations where the scattering medium one wish to look through is inhomogeneous. Here, we extend ASM by taking into account the spatial variation of the medium density, and propose a two-step method for imaging through inhomogeneous scattering media.

Azaphilone pigments from the marine-derived Penicillium sclerotium UJNMF 0503 and their neuroprotective potential against HO-induced cell apoptosis through modulating PI3K/Akt pathway.

Azaphilones represent a particular group of fascinating pigments from fungal source, with easier industrialization and lower cost than the traditional plant-derived pigments, and they also display a wide range of pharmacological activities. Herein, 28 azaphilone analogs, including 12 new ones, were obtained from the fermentation culture of a marine fungus Penicillium sclerotium UJNMF 0503. Their structures were elucidated by MS, NMR and ECD analyses, together with NMR and ECD calculations and biogenetic considerations.

Anisotropic medium sensing controlled by bound states in the continuum in polarization-independent metasurfaces.

Bound states in the continuum (BICs) with infinite quality factor (Q-factor) and significant field enhancement pave the way for realizing highly sensitive optical sensors with enhanced light-matter interactions on the nanoscale. However, current optical sensing methods are difficult to discriminate between isotropic and anisotropic media from resonance spectral lines, resulting in optical sensing methods still being limited to isotropic media. In this work, we demonstrate that BICs can be realized by modulating the period of structural units to convert BICs to QBICs without changing their space group symmetry, and propose a polarization-independent metasurfaces-based realization of highly sensitive refractive index sensors for isotropic and anisotropic media as well as discrimination.

Research on Multiscale Modeling and Experiment of CFRP Milling.

High-quality milling of carbon fiber reinforced polymer (CFRP) composites is of great importance for the high-performance manufacturing of structures made of this hard-to-machine material. In this paper, a multiscale finite element (FE) model, considering the thermal-mechanical coupling effect, was developed to simulate the milling process and reveal its material removal mechanism. The corresponding milling experiments were conducted to validate the simulated cutting forces and temperature, which were in good agreement with the experiment results.

Double U-groove temperature and refractive index photonic crystal fiber sensor based on surface plasmon resonance.

Based on double U-groove photonic crystal fiber (PCF), a surface plasmon resonance sensor with dual parametric detection of temperature and refractive index is proposed. The birefringence of PCF is increased by using germanium ions doped in the core and introducing U-shaped notches on both sides of the D-shaped fiber. The polished surface of the PCF is coated with gold film and PDMS as a temperature sensing channel, and the U-shaped groove is coated with gold film as a refractive index sensing channel.

A Cyclohexapeptide and Its Rare Glycosides from Marine Sponge-Derived sp. OUCMDZ-4539.

Pyridapeptide A (), a cyclohexapeptide containing hexahydropyridazine-3-carboxylic acid (HPDA), 5-hydroxytetrahydropyridazine-3-carboxylic acid (γ-OH-TPDA), and (2,3,4,6)-2-amino-3-hydroxy-8-methylnona-4,6-dienoic acid residues, and its four glycopeptides, pyridapeptides B-E (, respectively), were isolated from the fermentation broth of the marine sponge-derived sp. OUCMDZ-4539. Their structures were determined on the basis of spectroscopic analysis and chemical methods.

High Birefringence D-Shaped Germanium-Doped Photonic Crystal Fiber Sensor.

In this work, a surface plasmon resonance (SPR) sensor based on a D-shaped germanium-doped photonic crystal fiber (PCF) is proposed. The finite element method (FEM) is introduced to analyze the structure parameters, such as germanium-doped concentration, lattice pitch, and air hole size. In addition, the coupling properties and birefringence properties of PCF are also studied.

Tunable liquid crystal core refractive index sensor based on surface plasmon resonance in gold nanofilm coated photonic crystal fiber.

We propose, to the best of our knowledge, a novel kind of tunable liquid crystal core refractive index (RI) sensor based on photonic crystal fiber (PCF) covered with a nanoring gold film. The finite element method is used to discuss and analyze the sensing performance of the RI sensor. Gold is used as the excitation material for surface plasmon resonance, and a gold nanoring is embedded around the first cladding of the PCF.

Detection and Clinical Value of Circulating Tumor Cells as an Assisted Prognostic Marker in Colorectal Cancer Patients.

Background: Circulating tumor cells (CTCs) are cells that have been shed into the vasculature from a primary tumor and circulate in the bloodstream. It has been suggested that detecting CTCs could help the clinician to detect early metastasis or recurrence more effectively. This trial sets out to assess the detection and clinical value of CTCs as an assisted prognostic marker in patients with colon cancer and rectal cancer.

Effect of different reinforcement methods on anastomotic leakage prevention after laparoscopic double anastomosis.

Background And Objectives: To investigate the effects of different suture reinforcement methods for anastomotic leakage and other postoperative complications after the use of a laparoscopic double stapling technique (DST).

Methods: We collected the data of 124 patients who underwent laparoscopic radical resection of colorectal cancer from July 2017 to September 2018 at our institution. Patients were divided into three groups according to the suture reinforcement methods: intermittent, continuous suture reinforcement, and non-reinforcement (n = 41, 41, and 42, respectively).

Identification of 1-phenyl-4-cyano-5-aminopyrazoles as novel ecdysone receptor ligands by virtual screening, structural optimization, and biological evaluations.

Ecdysteroids initiate the molting process in insects by binding to the ecdysone receptor (EcR), which is a promising target for identifying insect growth regulators. This paper presents an in silico/in vitro screening procedure for identifying new EcR ligands. The three-step virtual screening procedure uses a three-dimensional pharmacophore model, docking and Molecular Mechanics/Poisson-Boltzmann Surface Area (MM/PBSA) rescoring routine.

Cytotoxic and antibacterial triterpenoids from the roots of Morinda officinalis var. officinalis.

Seven new pentacyclic triterpenoids including six ursane-type, marinoids A-F (1-6), and one oleanane-type, marinoid G (7), along with five known analogues (8-12), were separated from the roots of Morinda officinalis var. officinalis. Their structures were assigned by spectroscopic means especially analysis of 2D NMR data, with the absolute configurations of 1 and 2 being determined via comparison of their experimental ECD spectra with the computed ones.

Research on tunable distributed SPR sensor based on bimetal film.

In order to overcome the limitations in range of traditional prism structure surface plasmon resonance (SPR) single-point sensor measurement, a symmetric bimetallic film SPR multi-sensor structure is proposed. Based on this, the dual-channel sensing attenuation mechanism of SPR in gold and silver composite film and the improvement of sensing characteristics were studied. By optimizing the characteristics such as material and thickness, a wider range of dual-channel distributed sensing is realized.

Meroterpenoids and Isocoumarinoids from a Fungus Associated with .

Four new meroterpenoids ⁻ and four new isocoumarinoids ⁻, along with five known isocoumarinoids (⁻), were isolated from the fungus sp. OUCMDZ-2784 associated with the salt-resistant medicinal plant, (Apocynaceae). Their structures were elucidated by means of spectroscopic analysis, X-ray crystallography, ECD spectra and quantum chemical calculations.

Natural Products Research in China From 2015 to 2016.

This review covers the literature published by chemists from China during the 2015-2016 on natural products (NPs), with 1,985 citations referring to 6,944 new compounds isolated from marine or terrestrial microorganisms, plants, and animals. The emphasis is on 730 new compounds with a novel skeleton or/and significant bioactivity, together with their source organism and country of origin.

Identification, Bioactivity, and Productivity of Actinomycins from the Marine-Derived .

In the process of profiling the secondary metabolites of actinobacteria isolated from the Saudi coastal habitats for production of antibiotics and anti-cancer drugs, the cultures of strain WH1 that was identified as exhibited strong antibacterial activity against . By means of MS and NMR techniques, the active compounds were characterized as actinomycins X, X, and D, respectively. The research on the productivity of this strain for actinomycins revealed that the highest production of actinomycins X, X, and D was reached in the medium MII within 5% salinity and pH 8.

Diversity and function of the Antarctic krill microorganisms from Euphausia superba.

The diversity and ecological function of microorganisms associated with Euphausia superba, still remain unknown. This study identified 75 microbial isolates from E. superba, that is 42 fungi and 33 bacteria including eight actinobacteria.

[New natural products from the marine-derived Aspergillus fungi-A review].

Marine-derived fungi were the main source of marine microbial natural products (NPs) due to their complex genetic background, chemodiversity and high yield of NPs. According to our previous survey for marine microbial NPs from 2010 to 2013, Aspergillus fungi have received the most of attention among all the marine-derived fungi, which accounted for 31% NPs of the marine fungal origins. This paper reviewed the sources, chemical structures and bioactivites of all the 512 new marine NPs of Aspergillus fungal origins from 1992 to 2014.

Marine natural products sourced from marine-derived Penicillium fungi.

Marine micro-organisms have been proven to be a major source of marine natural products (MNPs) in recent years, in which filamentous fungi are a vital source of bioactive natural products for their large metagenomes and more complex genetic backgrounds. This review highlights the 390 new MNPs from marine-derived Penicillium fungi during 1991 to 2014. These new MNPs are categorized based on the environment sources of the fungal hosts and their bioactivities are summarized.