V-Induced Low-Spin State Mn Suppresses Jahn-Teller Distortion for High-Performance Aqueous Zinc Ion Batteries.

The Jahn-Teller distortion caused by high-spin state Mn (t e ) is a major limiting factor for improving both the specific capacity and cycling stability of MnO cathodes in aqueous zinc-ion batteries. Thus, an intrinsic strategy for optimizing MnO involves the effective elimination of the high-spin state Mn (t e ) during electrochemical process. Herein, we focus on structural design that constructed NHVO-coated MnO (Mn@V) nanorods to achieve the low-spin state of Mn (t e ) and inhibit the Jahn-Teller distortion.

A Large-Scale Image Repository for Automated Pavement Distress Analysis and Degradation Trend Prediction.

In recent years, automated detection technologies for large-scale pavement distress have become a focal point of research in the transportation sector. With the rapid advancement of deep learning technologies, data-driven artificial intelligence recognition algorithms have gradually emerged as the industry mainstream. The effectiveness of such algorithms largely depends on the reliability and quantity of the samples.

A large intraplate hydrogen-rich hydrothermal system driven by serpentinization in the western Pacific: Kunlun.

The Kunlun hydrothermal system near the Mussau Trench in the western Pacific consists of 20 large round/oval craters of hundreds of meters in diameter. The total area is 11.1 square kilometers, i.

Toxicity assessment of N, N-Diethyl-meta-toluamide (DEET) in zebrafish embryos.

N, N-Diethyl-meta-toluamide (DEET) is a widely used insect repellent that can be detected in water and soil worldwide. Although adverse reactions have been reported following the use of DEET - containing products, there are few toxicity studies. In this study, zebrafish were exposed to 0, 0.

Circulating T cell atlas in Moyamoya disease: insights into immunopathogenesis of cerebrovascular disorders.

Background: Moyamoya disease (MMD) is a chronic cerebrovascular disorder characterized by progressive stenosis or occlusion of the intracranial arteries, accompanied by the formation of fragile collateral vessels, ultimately leading to ischemic or hemorrhagic strokes. Immune dysregulation, particularly involving T cell abnormalities and mitochondrial dysfunction, plays a critical role in the pathogenesis of MMD; however, their precise relationship remains unclear.

Methods: Peripheral blood mononuclear cells (PBMCs) from patients with MMD and healthy controls were analyzed using mass cytometry (CyTOF) and transcriptomic profiling.

Radiomics-clinical nomogram for preoperative tumor-node-metastasis staging prediction in breast cancer patients using dynamic enhanced magnetic resonance imaging.

Background: Breast cancer is one of the most commonly diagnosed malignancies in women worldwide, and the disease burden continues to aggravate. The tumor-node-metastasis (TNM) staging information is crucial for oncology physicians to develop appropriate clinical strategies. This study aimed to investigate the value of a radiomics-clinical model for predicting TNM stage in breast cancer patients using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI).

Elevated accumulation of lutein and zeaxanthin in a novel high-biomass yielding strain Dunaliella sp. ZP-1 obtained through EMS mutagenesis.

Background: Dunaliella microalgae, such as Dunaliella salina riching in β-carotene and Dunaliella bardawil rich in lutein and α-carotene, have been used in aquaculture, supplements, cosmetics, and feed industries. The genus Dunaliella is diverse; therefore, characterization of novel strains and isolation of new varieties through mutagenesis technology will promote natural carotenoid bioproduction.

Results: Salt stress test demonstrated that the newly isolated microalgae strain ZP-1 was a halotolerant strain.

Boron-Fluoride Dual-atom Synergistic Regulated Interface Coating Enables Stable Zn-Metal Anodes.

Aqueous zinc-based batteries provide promising opportunities for next-generation rechargeable batteries. Nevertheless, Zn anode encounters severe challenges, such as Zn dendrite formation, surface corrosion, and hydrogen evolution reaction (HER). Here, we report a strategy to spontaneously construct a boron-fluoride dual-atom regulated SEI (ZnBOF), which involves the formation of a B-compound coating through an etching process followed by an in situ F substitution during the initial electrochemical cycling.

Integrated bulk RNA sequencing and mass cytometry analysis reveal the circulating immune landscape in ischemic and hemorrhagic Moyamoya disease.

Background: Moyamoya disease (MMD) is increasingly recognized as being influenced by chronic inflammation, with circulating immune cells playing a role in its progression. However, research on the immune characteristics of different MMD subtypes is limited. This study aims to compare the peripheral immune profiles of ischemic and hemorrhagic MMD patients.

Integrated Analysis to Reveal Heterogeneity of Tumor-Associated Neutrophils in Glioma.

Background: Glioma, characterized by its cellular and molecular heterogeneity, presents formidable challenges in treatment strategy and prognostic assessment. The tumor microenvironment (TME) profoundly influences tumor behavior and treatment response, with tumor-associated neutrophils (TANs) playing a complex but understudied role. This study aimed to investigate the heterogeneity and role of TANs in glioma and to develop a prognostic model.

Variant and Infectious Burden Associated With Intracranial Artery Stenosis in Moyamoya Disease.

Background: The mechanisms driving the progression of moyamoya disease (MMD) remain unrecognized. There is evidence suggesting that genetic and environmental factors may be associated with intracranial artery stenosis. Here, we aimed to investigate the characteristics of infectious exposure and the association of the (RING finger protein 213) variant and infectious burden (IB) with intracranial artery stenosis of MMD.

A Comprehensive Framework for Evaluating Cycling Infrastructure: Fusing Subjective Perceptions with Objective Data.

As cities increasingly prioritize green and low-carbon transportation, the development of effective cycling infrastructure has become essential for alleviating traffic congestion and reducing environmental impacts. However, the service quality of bike lanes remains inadequate. To address this gap, this study proposes a multi-data-fusion framework for evaluating bike lane "cycling friendliness", integrating subjective perceptions with objective metrics.

Taurine levels and long-term adverse cerebrovascular risk in moyamoya disease: A prognostic perspective study.

Background: Taurine has been proven to play a significant role in cardiovascular and cerebrovascular diseases, but its relationship with moyamoya disease (MMD) remains unclear. This study aims to investigate the association between serum taurine levels and long-term adverse cerebrovascular events in patients with MMD after revascularization.

Methods: This study involved 352 patients with MMD, from whom comprehensive clinical data and blood samples were collected.

Serum Creatine Levels as a Predictive Factor for Postoperative Cerebrovascular Events in Patients With Moyamoya Disease.

Background: Creatine is essential for energy storage and transfer within and outside cells. However, its relationship with cerebrovascular disease has not been fully explored. This study examined the association between serum creatine levels and postoperative cerebrovascular events, including transient ischemic attack (TIA), ischemic stroke, and hemorrhagic stroke, in patients with moyamoya disease (MMD).

Partially amorphous vanadium oxysulfide for achieving high-performance Li-ion batteries.

Vanadium-based materials exhibit a high theoretical capacity and diverse valence states, rendering them promising candidate anodes for lithium-ion batteries (LIBs). However, the cycling and rate performance are limited by their weak structural stability and electrical conductivity. Herein, a rational amorphization strategy has been developed to construct dual-anion vanadium oxysulfide nanoflowers (VSO NFs) with partial amorphous components and abundant oxygen vacancies as anode material for LIBs.

Association Between Folate Metabolism Risk, Collateral Circulation, and Hemorrhagic Risk in Moyamoya Disease.

Methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) polymorphisms are known risk factors for vascular diseases due to the impact on folate metabolism dysfunction and homocysteine (Hcy) accumulation. This study aimed to investigate the association between folate metabolism risk and hemorrhagic risk in moyamoya disease (MMD). In this prospective study, we enrolled 350 MMD patients with complete genotype data for MTHFR and MTRR.

miR-1224 Controls Mammal Cerebral Cortex Development by Targeting the 3'-UTR of the Dlx1 mRNA.

Neural precursor cells (NPCs) are a group of cells with self-renewal and multi-differentiation potential. MicroRNAs are required for neurogenesis in the central nervous system (CNS). Recent reports suggest that miR-1224 is important in human CNS diseases.

Crosstalk between CD180-overexpression macrophages and glioma cells worsens patient survival through malignant phenotype promotion and immunosuppressive regulation.

Background: Understanding the molecular mechanisms in immunosuppressive regulation is crucial for improving immunotherapeutic strategies. Macrophages, the major immune cells in tumor microenvironment (TME), play a dual role in tumor progression. CD180, primarily expressed in macrophages, remains unclear and requires further investigation.

Innate Immune Cell Profiling in Peripheral Blood Mononuclear Cells of Patients with Moyamoya Disease.

Moyamoya disease (MMD) is a rare cerebrovascular disease characterized by stenosis or occlusion of the internal carotid artery, thus leading to ischaemic and haemorrhagic strokes. Although genetic studies have identified ring finger protein 213 (RNF213) as a susceptibility gene, the low disease penetrance suggests that a secondary trigger, such as infection, may initiate disease onset. This study aimed to characterize the innate immune cell profile of peripheral blood mononuclear cells (PBMCs) of MMD patients via mass cytometry (CyTOF).

Prognostic value of morphology and hemodynamics in moyamoya disease for long-term outcomes and disease progression.

To explore the relationship between morphological and hemodynamic parameters, baseline characteristics, and long-term outcomes in patients with moyamoya disease (MMD) using a computational fluid dynamics model. We retrospectively reviewed 129 patients at Beijing Tiantan hospital between July 2020 and December 2021. Perioperative clinical variables and Suzuki stage were recorded.

Delayed predictive inference integration with and revision by low-competitive inference alternatives in Chinese narrative text reading.

When readers encounter information conflicting with the predictive inferences made earlier, they may update the outdated ones with new ones, a process known as predictive inference revision. The current study examined the revision of disconfirmed predictive inferences by the primarily weakly activated, thus low-competitive inference alternatives during Chinese narrative text reading among Chinese native speakers. We conducted an event-related brain potential (ERP) experiment to study the predictive inference revision with increasingly supportive information for the low-competitive predictive inference alternatives.

Single-cell mapping of peripheral blood mononuclear cells reveals key transcriptomic changes favoring coronary artery lesion in IVIG-resistant Kawasaki disease.

Background: Intravenous immunoglobulin (IVIG)-resistant Kawasaki disease (KD) poses a considerable challenge to patients and their families due to its severe complications. Previous researches have highlighted the critical role of immune disorders in its pathogenesis. However, fragmented studies based on isolated cases hinder a comprehensive understanding of this deadly illness.

Systemic immune-inflammatory markers and long-term prognosis after revascularization in Moyamoya disease: a retrospective study.

Background: Systemic immune-inflammatory markers combine various individual inflammatory cell parameters to comprehensively explore their relationship with the development and long-term outcomes of cardiovascular, cerebrovascular, and oncological disorders. The systemic immune-inflammatory marker index has not been extensively studied in terms of its impact on the long-term prognosis following cerebral revascularization in MMD patients. Our research aims to address this gap and improve the prediction of long-term outcomes for these patients.