Effects of resistance exercise on cognitive function, neurotrophic factors, brain structure, and brain function in older adults: A narrative review.

Cognitive decline is age-specific or related to dementia and Alzheimer's disease (AD), which poses great concern to older adults. Exercise contributes to cognitive gains, with aerobic exercise (AE) being the most commonly studied type. However, other types, such as resistance exercise (RE), have received less attention in exercise-cognition research.

Not primed to agree? Short or no effect of rhythmic priming on typical adults processing number agreement.

Accumulating evidence shows improved syntactic processing after exposure to a rhythmically regular compared to an irregular musical prime, environmental noise, or silence. One potentially shared system between musical rhythm and language processing may be responsible for the construction of hierarchical sequences. Following findings of a shorter-lived rhythmic priming effect in Jabberwocky and more precise neural tracking of linguistic constituents in natural language than in Jabberwocky, the present study hypothesized that (a) hierarchical structure building constitutes a key shared mechanism between rhythm and language processing and (b) semantic information may also play a role in structure building.

"Sisters Are Doin' It for Themselves": Gender Differences in Singles' Well-Being.

The experience of singles has been largely overlooked in relationship science, garnering a need for understanding correlates of singles' well-being. Gender is an important focus of well-being research, and qualitative work on singlehood has suggested that men and women may have experiences of singlehood that differ in important ways. In this study ( = 5941; 50% men; = 31.

Rates of successful conceptions according to COVID-19 vaccination status: Data from the Czech Republic.

BackgroundAdverse effects of COVID-19 vaccination on human menstrual cycle characteristics have been observed, but limited data are available on the relationship between COVID-19 vaccination status and birth rates.ObjectivesTherefore, we used nationwide data from the Czech Republic to examine rates of successful conceptions (SCs), that is, conceptions leading to live births 9 months later, for women who were either vaccinated or unvaccinated against COVID-19 before SC.MethodsSummary monthly COVID-19 vaccination and birth data for women in the Czech Republic aged 18-39 years were retrieved for the period from January 2021 to December 2023.

Higher socioeconomic status is associated with dispensation of monoclonal antibodies against calcitonin gene-related peptide in migraine: A nested case-control study.

BackgroundHigher socioeconomic status (SES) among people with migraine has been associated with an increased use of triptans, but it is undetermined whether high SES is also associated with dispensation of monoclonal antibodies against calcitonin gene-related peptide (CGRPi), a prophylactic treatment against migraine episodes. Our hypothesis was that higher SES is associated with CGRPi dispensation, although the association is expected to be attenuated in a country that generally allows for reimbursement of CGRPi costs.MethodsIn this register-based nested case-control study, the association between SES, categorized into three levels (low, middle and high) and the outcome of a first dispensation of a CGRPi was assessed among people with a migraine diagnosis in Region Stockholm, using univariable and multivariable logistic regression models.

Effects of high doses of statins to prevent contrast-induced acute kidney injury, based on cystatin C levels: A meta-analysis.

ObjectiveThe potential benefit of measures to prevent contrast-induced acute kidney injury (CIAKI) remains uncertain. This uncertainty is partly due to the reliance on serum creatinine, a biomarker influenced by non-renal factors such as muscle mass, hydration status, and age. Therefore, this study aims to evaluate CIAKI prevention based on cystatin C levels-a more stable and earlier biomarker of renal dysfunction, which may improve diagnostic precision and the assessment of therapeutic efficacy.

Poets Over Quants: Automation and AI Threats Increase the Value People Place on Creativity.

We examine how perceived automation and AI threats (the belief that advanced technology threatens humans' career prospects) shape workers' strategies for career preparation. In nine studies ( = 2,320; three preregistered), we find that perceived automation threat drives people to prioritize creative skills over technical and social skills. A pilot study revealed that people view creativity as less prone to automation and more likely to complement automation.

Factors Associated with Intent to Leave and Burnout among Canadian Nurses Amidst the COVID-19 Pandemic: A Quantitative Analysis of the Survey on Health Care Workers' Experiences During the Pandemic.

BackgroundThe increased demands and stressors from the COVID-19 pandemic led to widespread burnout and job stress, prompting concerns about retention rates. This study identifies demographic and occupational predictors of Canadian nurses' intent to leave their jobs due to burnout and job stress during the COVID-19 pandemic.MethodsData was utilized from the Survey on Health Care Workers' Experiences During the Pandemic conducted by Statistics Canada.

Recommending 24-hour attendant care: A qualitative study exploring the clinical decision-making process of occupational therapists in Ontario, Canada.

ObjectiveThis study aims to explore how occupational therapists working in private practices in Canada use clinical indicators and tools to determine if clients require 24-hour attendant care.DesignA qualitative research study.SettingThe setting involved semi-structured, one-on-one interviews with occupational therapists in Canada.

High-Load Strength Training Reduces Injury Incidence and Injury Burden and Improves Physical Fitness in Young Highly Trained Soccer Players.

Background: There is little available information on the reduction of injury incidence and injury burden after strength training programs. This study aimed to analyze the effects of a 12-week high-load strength training program on injury incidence, injury burden, and fitness in young, highly trained, soccer players.

Hypothesis: It was hypothesized that well-targeted high-load training focused on the gluteal and hamstring musculature could aid in injury prevention and increase physical fitness.

Evidence-based guidelines for the pharmacological treatment of migraine.

We here present evidence-based guidelines for the pharmacological treatment of migraine. These guidelines, created by the Italian Society for the Study of Headache and the International Headache Society, aim to offer clear, actionable recommendations to healthcare professionals. They incorporate evidence-based recommendations from randomized controlled trials and expert-based opinions.

Individual and combined contamination of the toxic metals in commercial cat and dog food.

As the long-term accumulation of toxic metals in food poses significant health risks to pets, there is a growing concern among people regarding toxic metal contamination in pet food. In order to investigate the toxic metals levels in pet food in China, we collected a total of 93 imported cat and dog food from the Chinese market produced in 2021-2022, comprising 45 cat food and 48 dog food, and determined the concentrations of lead (Pb), cadmium (Cd), chromium (Cr), mercury (Hg) and arsenic (As) in them. The concentrations of Pb, Cd and Cr were determined by flame atomic absorption spectrometry, while Hg and As were quantified by atomic fluorescence spectrometry.

Allan Kardec's theories and methods to investigate the nature of psychical experiences.

The French educator Allan Kardec (1804-1869) was one of the first researchers to propose the scientific investigation of psychical experiences and was an influential scholar in Europe during the second half of the 19th Century. However, his life and the outcome of his research in this field are currently little known and often misconstrued. This paper briefly presents Kardec's biography and his first steps in the investigation of psychical phenomena, especially mediumship.

A Mixed-Methods Analysis of Negative Patient Experiences in Emergency Department Care: Identifying Challenges and Evidence-Informed Strategies Across the Care Continuum.

This mixed-methods study explores negative patient experiences within emergency departments (EDs), aiming to uncover systemic challenges and propose evidence-informed solutions. Of 2114 shared ED experiences, 306 (14.5%) were reported as "bad" or "very bad.

Cross-national variation in how members of the community define flourishing mental health.

Background: The experience of flourishing (i.e. high wellbeing) is informing our understanding of psychological health beyond psychopathology.

Setting higher standards for migraine prevention: A position statement of the International Headache Society.

Migraine is one of the most prevalent and disabling neurological diseases, significantly affecting quality of life and productivity, as well as contributing to substantial societal costs. Recent innovations, including calcitonin gene-related peptide (CGRP) pathway inhibitors and onabotulinumtoxinA, have transformed migraine prevention by offering high efficacy and excellent tolerability, thus improving adherence. Clinical trials and real-world studies show that significant reductions in migraine frequency and, in some cases, complete migraine freedom is achievable.

Barriers and facilitators to treat-to-target in axial spondyloarthritis in clinical practice: a mixed methods study.

This study aimed to explore the perceptions of patients and rheumatologists about a treat-to-target (T2T) strategy in axial spondyloarthritis (axSpA) and identify the barriers and facilitators to its implementation in clinical practice. A mixed methods design was applied. Patients with axSpA who visited the outpatient clinic with active disease (AxSpA Disease Activity Score [ASDAS] ≥ 2.

Do you have depression? A summative content analysis of mental health-related content on TikTok.

Background: TikTok is a global social media platform with over 1 billion active users. Presently, there are few data on how TikTok users navigate the platform for mental health purposes and the content they view.

Objective: This study aims to understand the patterns of mental health-related content on TikTok and assesses the accuracy and quality of the advice and information provided.

The MED13L Foundation strategic research plan: a roadmap to the future.

A strategic research plan (SRP) serves as a compass for the patient advocacy organizations driving the therapeutic options for their rare disorder. The MED13L Foundation commissioned the SRP in 2022 through COMBINEDBrain, a consortium of patient advocacy organizations of rare neurodevelopmental disorders, working toward clinical trial readiness. The MED13L Foundation SRP is an objective evaluation of MED13L literature including clinical and basic science knowledge interwoven with an assessment of preclinical trial readiness tools necessary for achieving therapeutic interventions.

Overuse of analgesics can affect the fertility biomarker Anti-Müllerian Hormone in females. A translational study.

Background: Medication overuse headache is a prevalent secondary headache due to the overuse of analgesics, mainly over-the-counter analgesics. Over-the-counter analgesics have been associated with disrupted male endocrinology, while the effects on female endocrinology remain nearly unknown. The aim was to understand the effect of long-term analgesic exposure in females with medication overuse headache on Anti-Müllerian hormone, a surrogate measure of female fertility.

Motivation, self-determination, and reflexivity of researchers in comedic public engagement.

Understanding motivation and impact of participation in public engagement programs is crucial for fostering dialogue between researchers and the public. Using Self-Determination Theory and Reflexive Thematic Analysis, in this study we analyzed motivation and impact on identity of researchers participating in Bright Club Ireland, a public engagement project where academic researchers learn to use stand-up comedy as an informal and accessible means of communicating their research, then perform at a public-facing variety night alongside professional comedians. Through semi-structured interviews and focus groups, we found that participation in Bright Club is largely intrinsically motivated, driven by researchers' desire to gain skills, be recognized as experts, and present their own perspectives on their disciplines.

The Use of Nudge Strategies in Improving Physicians' Prescribing Behavior: A Systematic Review and Meta-analysis.

Background: Nudges have been proposed as a method of influencing prescribing decisions.

Purpose: The purpose of this article is to 1) investigate associations between nudges' characteristics and effectiveness, 2) assess the quality of the literature, 3) assess cost-effectiveness, and 4) create a synthesis with policy recommendations.

Methods: We searched health and social science databases.

Implementing Arts on Prescription at Home for People Living With Dementia: A Hybrid-Effectiveness Feasibility Study.

Arts on prescription at home (AoP@Home) is a participatory art-based approach involving a professional artist engaging a person with dementia (and their family carer) in art-making in their own home. This study evaluated the implementation of AoP@Home within a real-world community aged care context. A hybrid effectiveness-implementation design was used to simultaneously test both the AoP@Home intervention and the implementation process.

Setting Appropriateness and Romantic Relationship Initiation Success.

Does the setting in which a relationship initiation attempt occurs matter to its success? Identical initiations could yield differential success if enacted in different settings. Data from five independent samples highlight the role settings play in the perception of (hypothetical) relationship initiation attempts and (expectations of) their success. Study 1a sourced a wide variety of settings for real-world relationship initiations.