Microwave-assisted subcritical water extraction of low methoxyl pectin from pistachio industry waste: Optimization, characterization, emulsification, and gelation mechanism.

This study investigates the extraction, optimization, and characterization of pectin from pistachio industry waste (PIW) using microwave-assisted subcritical water extraction (MASWE) without acid. Two different low-methoxyl pectins (LMP) were observed. The first pectin variant (MASWE100) was extracted at a pressure of 3 MPa, a temperature of 100 °C, and an irradiation time of 4 min.

Security practices and insider threats in Spanish healthcare centers: a survey-based risk assessment.

Introduction: Insider threats pose a critical risk in healthcare environments, where Hospital Information Systems (HIS) manage sensitive patients data. Authorized users may intentionally or accidentally compromise data confidentiality, integrity, and availability. This study assessed information security practices from the perspective of healthcare professionals in Spanish medical centers.

Physiological and Phytochemical Responses of L. to End-of-Day Red/Far-Red and Green Light.

L. is a widely used medicinal plant whose secondary metabolism and morphology are influenced by light. This study evaluated the effects of 2 and 4 h end-of-day (EOD) red/far-red (R:FR) and green (G) light on the growth, physiology, and phytochemical profile of hydroponically grown under a constant red/blue light background, compared with a red/blue control without EOD treatment.

Strategic ownership configurations to foster intangible cultural heritage in Japanese football events.

Introduction: This study examines how different configurations of the Ownership Landscape influence the preservation of Intangible Cultural Heritage in sporting events, using Japan as a case study. Drawing on the Resource-Based View, it explores how ownership models act as strategic resources that affect both cultural sustainability and long-term competitiveness.

Methods: A qualitative multiple-case study was conducted on four football-related events: the J.

Impact of Starting Status and Match Outcome on Peak Match Demands in Semiprofessional Soccer Players.

This study aimed to determine the peak locomotor match demands between starters and non-starting soccer players according to playing position and match outcome. Twenty-two young outfield soccer players were observed over 17 official matches. Locomotor performance during the matches was recorded per minute: total distance (TD), high-speed running distance (HSD, >19.

Maximising biodiversity potential in Europe's mines and quarries: A key role for EU Nature Restoration Regulation targets.

Amid the UN Decade on Ecosystem Restoration and the EU's Nature Restoration Regulation (NRR), which aims to restore degraded areas in the coming decades, post-mining sites must be integrated into biodiversity and ecosystem recovery strategies as key contributors. While mining, quarrying, and other extractive activities have considerable environmental impacts, they also present massive opportunities to create valuable habitats, support biodiversity, guide restoration efforts, and contribute to conservation. A strong foundation of scientific and practical knowledge is already in place, yet implementation gaps persist, and regulatory frameworks remain under-utilised for restoring these degraded areas.

Translational biomarkers for integrated cardiovascular disease risk assessment: A multidisciplinary review with applications in precision medicine.

Aims: Cardiovascular disease (CVD) continues to be a leading cause of morbidity and mortality, significantly impacting healthcare systems and individual lives. This pragmatic review focuses on the assessment of CVD utilizing traditional and emerging risk factors that provide a basis for personalized medicine and precision nutrition, highlighting the knowledge and application of these insights for accurate risk diagnosis, individualized interventions, and precise outcome/evaluation prognosis.

Data Synthesis: Critical biochemical markers such as lipid metabolism signatures, inflammatory molecules, endocrine mediators, homeostatic signals (including omics data), and lifestyle factors such as unhealthy dietary habits, physical inactivity, smoking, alcohol abuse, along with anthropometric variables and body composition measurements, play a pivotal role in assessing and managing CVD.

Towards syngas biorefineries: The potential of microbial consortia for syngas valorisation.

Gasification has emerged as a promising platform to cope with recalcitrant organic waste within the framework of biomass-based biorefineries, producing syngas that can be fermented into valuable bioproducts. Despite its potential, syngas fermentation is based predominantly on pure cultures, which faces significant challenges, including the limited portfolio of generated compounds (primarily acetate and ethanol) and their low productivity. To address these bottlenecks, the potential of microbial consortia as effective platforms for syngas conversion has been evaluated.

The Influence of Mediterranean and Western Dietary Patterns on Sensory Perception and Taste Sensitivity: A Study Among University Students.

This study examines the relationship between dietary patterns, specifically the Mediterranean diet (MD) and the Western diet (WD), and sensory perception among nursing students at the University of Valladolid, Spain. The study aims to understand how these dietary patterns affect taste sensitivity and preferences, contributing to the fields of nutrition and sensory science. A total of 41 students participated in this study, following ethical guidelines.

A Machine Learning Approach to Understanding the Genetic Role in COVID-19 Prognosis: The Influence of Gene Polymorphisms Related to Inflammation, Vitamin D, and .

The genetic background influences the outcomes of COVID-19. This study aimed to evaluate the incidence of polymorphisms in genes linked to the RAAS system, cytokine production, and vitamin D on COVID-19 severity, with the goal of gaining a deeper understanding of the genetic etiology related to COVID-19. This study involved 338 COVID-19 patients and employed machine learning methods to identify the genetic variants that most significantly affect COVID-19 severity.

Loneliness and Isolation in the Era of Telework: A Comprehensive Review of Challenges for Organizational Success.

As remote work becomes increasingly prevalent, scholarly and organizational attention has largely centered on stress and workload. However, emerging evidence highlights loneliness and isolation as critical yet underexplored factors with profound implications for employees' mental health and organizational performance. This study conducts a bibliometric review of 65 peer-reviewed articles indexed in the Scopus database, following PRISMA guidelines and employing VOSviewer for data analysis and visualization.

Perceived Physical Literacy Levels in Spanish Adolescents: Differences Between Sexes and Age Groups.

: Perceived physical literacy (PPL) appears to be a relevant strategy for combating the prevalent sedentary lifestyle among young people. Therefore, understanding their PPL levels will facilitate the implementation of appropriate strategies for this purpose. Therefore, this study aimed to analyze the differences in PPL considering the sex dimension (i.

Association Between Oxidative-Inflammation Biomarkers and Incident Chronic Kidney Disease in People with High Cardiovascular Risk: A Nested Case-Control Study.

: To assess oxidative-inflammatory biomarker prediction of incident CKD after 1-year follow-up in a population with overweight/obesity and metabolic syndrome. : Prospective nested case-control study comprising 117 CKD incident cases and 117 matched controls free of CKD after 1-year follow-up conducted in 55-75-year-old participants. Controls were time-matched 1:1 to cases by intervention group, age (≤65 vs.

Theory of Mind Development in Deaf and Hard-of-Hearing Individuals: A Systematic Review.

Theory of Mind (ToM) is a construct that includes a range of connected abilities linked to the understanding of others' mental states. During the last three decades, ToM development has been studied extensively in deaf and hard of hearing (DHH) individuals and performances compared to the typically hearing (TH) population. Given the advances in the early diagnosis of deafness, interventions, and hearing devices over this period, variations in task performance among DHH participants might have been reduced.

Exploring anaerobic fermentation stability against a temperature perturbation: process indicators and recovery strategies.

Anaerobic fermentation (AF) efficiency is highly influenced by temperature, and operational disruptions in industrial settings can lead to severe process failure. In this study, AF of food wastes (FWs) was subjected to a temperature drop from 25 °C to 15 °C to elucidate AF behaviour and proper recovery strategies. The temperature decrease caused a marked decline in volatile fatty acids (VFAs) production from 23.

Intraocular pressure values in the Iberian Peninsula: epidemiological study and influencing factors.

Purpose: The aim of this study is to provide an update on the intraocular pressure measurements in Iberian Peninsula in order to elucidate their relationships with other clinical factors.

Methods: A multicentric cross-sectional prospective study was carried out on patients attending General Optica centres in Spain and Portugal in collaboration with the University of Valladolid. This study included healthy patients with 18 years and older.

Pharmacoproteomics in the development of personalised medicine in Age-related Macular Degeneration (PHARPRO-AMD) study protocol.

Introduction: Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss among people over 55 years of age globally, being neovascular AMD (nAMD) its most aggressive form. Its treatment consists of the use of drugs that block vascular endothelial growth factor (anti-VEGF). Proteomics may allow the identification of differentially expressed proteins between responders and non-responders to each anti-VEGF drug.

Dual-mode optical thermometry based on up- and down-conversion photoluminescence in LiCaLa(MoO):Er/Yb phosphors with high sensitivity.

The integration of down-conversion (DC) and up-conversion (UC) photoluminescence mechanisms has attracted significant attention for applications in optical thermometry and solid-state lighting. Combining both emission processes within a single material enables dual-mode temperature sensing, offering enhanced flexibility and precision. In this study, we report a pioneering investigation of the dual-mode thermometric performance of LiCaLa(MoO) phosphors co-doped with Er (0.

Interlaboratory validation of an optimized protocol for measuring α-amylase activity by the INFOGEST international research network.

The activity of α-amylases is frequently determined using a single-point assay at 20 °C. Previous work within INFOGEST "Working Group 5 - Starch digestion and amylases" identified significant interlaboratory variation with this protocol. The current study aimed to evaluate the repeatability (intralaboratory precision) and reproducibility (interlaboratory precision), measured as coefficients of variation (CVs), of a newly optimized protocol version based on four time-point measurements at 37 °C.

Contrast Sensitivity Comparison of Daily Simultaneous-Vision Center-Near Multifocal Contact Lenses: A Pilot Study.

Our purpose is to evaluate the binocular contrast sensitivity function (CSF) in a presbyopic population and compare the results obtained with four different simultaneous-vision center-near multifocal contact lens (MCL) designs for distance vision under two illumination conditions. Additionally, chromatic CSF (red-green and blue-yellow) was evaluated. A randomized crossover pilot study was conducted.

Effect of transcranial magnetic pulses on cortical network connectivity in schizophrenia.

Introduction: Transcranial magnetic stimulation (TMS) pulses applied to the cortex induce dynamic changes in brain network activity. These changes are useful for the in vivo study of functional connectivity, which may be characterized with the application of network parameters to the pre-stimulus (i. e.

Academic performance and anxiety in the evaluation of health science undergraduate students using osce: a pre- and post-covid-19 cohort study.

Background: The education of health science students requires the use of assessment tools that provide valid and reliable information about the learning of practical skills. The objective and structured clinical evaluation (OSCE) method has been shown to be useful, but it can cause stress and anxiety, which may increase after COVID-19 affects final academic performance. To test whether the OSCE induces an anxiety response in participants, to analyse the cause of this emotional response and to examine the relationship between OSCE scores and students' final performance.

Reducing carbon footprint in high HS emissions: A synergistic microalgal-bacterial solution for sugarcane biorefineries.

Sugarcane vinasse, a major by-product of ethanol production, poses environmental and health risks due to its high sulfate content, promoting severe hydrogen sulfide (HS) formation (up to 50,000 ppm) during acidogenic fermentation. The resulting HS and high carbon dioxide (CO) levels in off-gas create serious hazards, often leading to conventional desulfurization systems' clogging and high maintenance. This study is the first to investigate a Chloroidium-based combined microalgal-bacterial (CMB) system for simultaneous, high-strength HS abatement and CO sequestration from these challenging vinasse fermentation off-gas streams.

Determinants of quality of life in long-COVID patients with new-onset chronic pain.

Chronic pain is highly prevalent in Long-COVID syndrome and significantly impacts quality of life (QoL). Given the complexity of long-COVID, a comprehensive approach is necessary to understand how the interactions of psychosocial, pain and functional factors may influence patients' well-being. This study aimed to explore key factors associated with QoL in long-COVID patients with new-onset chronic pain, and to multidimensionally characterize this population.

Deproteinization and controlled starch prehydrolysis in intact pulse cotyledon cells regulates starch retrogradation and digestion.

Intact pulse cotyledon cells are known for their intact cellular structure and dense protein matrix, leading to slower starch digestibility. However, the retrogradation and digestibility of retrograded intracellular starch has rarely been investigated, and our preliminary results indicated the difficulty of intracellular starch retrogradation. To test mechanistic principles of intracellular starch retrogradation, intact pulse cells were extracted and treated with protease followed by pancreatic α-amylase (0-20 min) and pullulanase (24 h) prehydrolysis, and then controlled retrogradation (4 °C, 5 d).