Deep learning signature to predict postoperative anxiety in patients receiving lung cancer surgery.

This study aims on establishing and validate a deep learning signature based on magnetic resonance imaging (MRI) to predict postoperative anxiety in patients receiving lung cancer surgery. In the current study, 202 patients receiving lung cancer surgery were included. Preoperative MRI-T1WI images were collected to train the deep learning signature utilized the ResNet-152 algorithm.

Biocompatible Discopodium Ppenninervium loaded chitosan-PVA electrospun fibrous scaffold wound dressing.

Biocompatible electrospun fibrous scaffolds that mimic the extracellular matrix (ECM) have significant potential in tissue engineering and wound healing applications. This study aimed to develop a novel scaffold by incorporating Discopodium penninervium (DP) leaf extract into chitosan-polyvinyl alcohol (CH-PVA) scaffolds via electrospinning and evaluate their biocompatibility, antibacterial properties, and efficacy in wound healing. Gas chromatography-mass spectrometry (GC-MS) analysis identified bioactive compounds in the DP extract, including phenolic acids, phytol, linolenic acid, and gamma-sitosterol, which are known for their anti-inflammatory, antioxidant, and skin-regenerative properties.

Integration of high strength, flexibility, and room-temperature plasticity in ceramic nanofibers.

The developing cutting-edge technologies involving extreme mechanical environments, such as high-frequency vibrations, mechanical shocks, or repeated twisting, require ceramic components to integrate high strength, large bending strain, and even plastic deformation, which is difficult in conventional ceramic materials. The emergence of ceramic nanofibers (CNFs) offers potential solutions; unfortunately, this desirable integration of mechanical properties in CNFs remains unrealized to date, due to challenges in precisely modulating microstructures, reducing cross-scale defects, and overcoming inherent contradictions between mechanical attributes (particularly, high strength and large deformation are often mutually exclusive). Here, we report a nucleation regulation strategy for crystalline/amorphous dual-phase CNFs, achieving an extraordinary integration of high strength, superior flexibility, and room-temperature plasticity.

All-stage targeted nanodiscs for glioma treatment by inducing cuproptosis and apoptosis of cancer cells and cancer stem cells.

There remain several intractable challenges for chemotherapy in glioma treatment, including the blood-brain barrier (BBB), blood-brain tumor barrier (BBTB), and tumor heterogeneity caused by cancer stem cells (CSCs), which are resistant to conventional chemotherapy. Here, we established a nano strategy to kill glioma cells and CSCs, combining carfilzomib and bis(diethyldithiocarbamate)copper. The synergistic drug combination disturbed cell protein metabolism at different stages and induced apoptosis and cuproptosis.

A study on the functional design and comfort of knee pads for delivery workers.

In this study, four types of functional knee pads with structure partitions were designed for delivery workers based on leg movement patterns during delivery. By selecting three characteristic points of the knee, experiments were conducted with the subjects to objectively analyze the effects of the knee pads with different fabrics on thermal and pressure comfort. The results showed that the structural partition of the knee pads with different fabrics had a significant effect on temperature; sample 3 had the highest temperature at the end of the experiment, which increased by 0.

Facile synthesis of rapid hemostatic powder based on sodium alginate for promoting hemostasis and wound healing.

Uncontrollable bleeding and excessive blood loss are the primary causes of death on the battlefield and in accidents. However, commercial hemostatic materials possess individual drawbacks for hemostasis. Here, we present a rapid hemostatic powder (SACC-GO) with high biosafety, which is fabricated by a facile ball milling method using inexpensive raw materials (sodium alginate (SA), calcium chloride, cerium nitrate and graphene oxide (GO)).

Mineralized cellulose nanofibers reinforced bioactive hydrogel remodels the osteogenic and angiogenic microenvironment for enhancing bone regeneration.

Slow osteogenesis and insufficient vascularization remain significant challenges in achieving effective bone repair and functional restoration with tissue-engineered scaffolds. Herein, a novel mineralized nanofibers reinforced bioactive hydrogel was designed to enhance bone regeneration inspired from the structural and functional properties of the bone tissue extracellular matrix (ECM). This bioactive hydrogel integrated enzymatically mineralized TEMPO-oxidized bacterial cellulose (m-TOBC) nanofibers and mesoporous silica nanoparticles (MSNs) loaded with the angiogenic drug dimethyloxalylglycine (DMOG) into gelatin methacryloyl (GelMA).

Heteroatom decorated C2N monolayer for gas-sensing application: Insight from first-principles.

Development of novel gas-sensing materials is essential to high-performance gas sensors for monitoring target gases in industrial production and environmental protection. Herein, we investigate two types of the heteroatom-decorated C2N monolayer, denoted as M@C2N (M = Mn and Ni) and B-C2N, for their gas-sensing functionality toward seven small gaseous molecules (H2, O2, N2, CO, CO2, NH3, and H2O). The key gas-sensing characteristics concerning chemiresistive (CR) and field-effect transistor (FET) gas sensing have been thoroughly explored.

Experimental Study on Ultrasonic Vibration-Assisted Grinding of SiCp/Al Composites Grinding.

Aluminum matrix composites reinforced with silicon carbide particles (SiCp/Al) are widely used in aerospace fields with excellent properties, such as high specific strength, high specific stiffness, and high thermal conductivity. Due to the heterogeneous structure, its microstructure is one of the determinants of workpiece life, and ultrasonic vibration can improve the surface quality after grinding. Therefore, in this study, ultrasonic vibration-assisted grinding (UVAG) orthogonal tests were designed to study the surface morphology of SiCp/Al and the form of SiC particle removal under different machining parameters based on the SEM observation of the material surface, and to analyze the percentage of different kinds of grinding forces.

Electrospun Fiber Membranes Modified with Heparin and Parathyroid Hormone Derivative To Promote Diabetic Wound Healing.

The repair of diabetic wounds is a global challenge due to elevated levels of blood sugar and microvascular disorders. Parathyroid hormone (PTH) and its derivatives show great potential for wound healing, but corresponding delivery strategies are still limited. Herein, a novel electrospun fiber membrane whose surface is modified with heparin is fabricated to deliver a PTH derivative named parathyroid hormone related peptide-1 (PTHrP-1) for the healing of diabetic wounds.

NiO/ZnO Nanocomposites for Multimodal Intelligent MEMS Gas Sensors.

Gas sensor arrays designed for pattern recognition face persistent challenges in achieving high sensitivity and selectivity for multiple volatile organic compounds (VOCs), particularly under varying environmental conditions. To address these limitations, we developed multimodal intelligent MEMS gas sensors by precisely tailoring the nanocomposite ratio of NiO and ZnO components. These sensors demonstrate enhanced responses to ethylene glycol (EG) and limonene (LM) at different operating temperatures, demonstrating material-specific selectivity.

A binuclear zinc complex (ZnL) as ratiometric probe for the pyrophosphate (PPi) sensing.

Phosphate anion (PPi) as hydrolysis products of adenosine triphosphate (ATP), is related to various biochemical reactions, particularly energy storage and transfer, nucleotide metabolism, and cellular signaling. In this paper, a binuclear zinc complex (ZnL) was prepared for the PPi sensing in Tris-HCl solution. The results showed a clear fluorescence change from blue to green (425 nm → 500 nm) with the addition of PPi to the probe.

Higher order volatile fatty acid metabolism and atypical polyhydroxyalkanoate production in fermentation-enhanced biological phosphorus removal.

Enhanced biological phosphorus removal (EBPR) is an established wastewater treatment process, but its wider implementation has been limited by factors like high temperature and low carbon availability. Fermentation-enhanced EBPR (F-EBPR) processes have shown promise in addressing these limitations, but the underlying mechanisms are not fully understood. This study investigates the metabolism of higher order (C) volatile fatty acids (VFAs) in F-EBPR systems using a combination of carbon isotope labelling and shotgun metagenomic sequencing analyses.

Development of highly robust polyurethane elastomers possessing self-healing capabilities for flexible sensors.

Traditional flexible electronic sensing materials have fallen short in meeting the diverse application needs and environments of modern times. Hence, we require a multi-functional elastomer material to improve the overall performance and expand the functionality of flexible electronic sensors. In this study, we fabricated a multi-block polyurethane (PU) elastomer based on semi-crystalline polycaprolactone (PCL) chain segments and highly flexible polydimethylsiloxane (PDMS) chain segments, which showcases outstanding mechanical properties, self-healing capabilities, and recyclability.

Weakly coupled relaxor construction in lead-free ferroelectrics with simple composition for superior energy-storage performance.

The development of advanced environmentally friendly energy storage capacitors is critical to meet escalating demands of pulsed power systems. However, challenges persist in enhancing both the recoverable energy density () and efficiency () simultaneously. In the present study, a strategy involving domain configuration modulation, achieved by simple single rare earth ion doping, was proposed to enhance the energy-storage performance of BaTiO.

Constructing chelating organic macrocycles inside the pores of hybrid mesoporous silica to intensify the toxic metal recovery ability.

Inorganic-organic hybrid mesoporous silicas have been considered some of the most effective matrices for the adsorption of potentially toxic species from aqueous and non-aqueous media. Among them, SBA-15 porous silica is superior due to its all-connected large pores associated with the intrinsic high surface area of this class of materials. Herein, we take advantage of the high pore volume of SBA-15 and form large organic macrocycles containing basic centres inside the mesopores to potentialize the toxic metal adsorption ability from aqueous waste water.

Research on the impact of tourism cooperation on urban public health.

Introduction: Tourism cooperation is increasingly recognized as a key driver of regional economic development, playing a crucial role in facilitating internal circulation and enhancing urban public health. This study examines the relationship between tourism cooperation and urban public health development, with a focus on China.

Methods: Using data from 284 Chinese cities over the period 2011-2022, this research measures both the degree of tourism cooperation and the level of urban public health development.

Solving Minimum Spanning Tree Problems Based on DNA Chemical Reaction Networks.

Introduction: DNA strand displacement reactions are emerging as a promising biocomputing tool. The minimum spanning tree problem is fundamental in graph theory. This paper explores the use of DNA strand displacement reaction networks for addressing the minimum spanning tree problem.

Promoting Healthy Aging: Physical Activity and Its Dual Effects on Physical Health and Cognitive Function in Chinese Older Adults.

Background: With the acceleration of societal aging, the physical health and cognitive function issues of seniors have increasingly garnered widespread attention. This article explores the impact of physical activity on the physical health and cognitive performance of seniors, aiming to provide a theoretical basis for health management and related policy formulation for seniors, which holds significant academic value and social significance.

Methods: This study constructs an ordered logit regression model to analyze the effects of physical activity on the physical health and cognitive performance of seniors, serving as the baseline model, and conducts a parallelism test to verify the model's applicability.

Deciphering decarbonization trajectories in China by spatiotemporal-accumulation modeling of electricity carbon footprint.

Recent climate-trade policies emphasize managing carbon embedded in goods, with electricity carbon footprints as a key metric. However, the rapid energy transition complicates this evaluation. An innovative spatiotemporal model, accounting for dynamically-installed low-carbon energy infrastructure (LCPI), was developed to assess electricity decarbonization trajectories.

Sustainable and robust polypyrrole/carbon nitride/regenerated cellulose fiber with visible-light-enhanced capacitance and bacterial inactivation.

With the rise of wearable devices, it is important but challenge to develop flexible energy storage materials that combine excellent mechanical properties, good electrochemical properties, and other functions. Here, a polypyrrole (PPy)/carbon nitride (CN)/regenerated cellulose composite fiber (PCCF) was firstly fabricated through a straightforward in situ polymerization and wet spinning process. The results show that PCCF can well balance mechanical properties, visible light antibacterial property and energy storage when compared to PPy/regenerated cellulose composite fiber (PCF).

Recent advances and perspectives in bioresorbable metal coronary drug-eluting stents.

Intervention without implantation has become a requirement for developing percutaneous coronary intervention for coronary heart disease. In this paper, the recent advances of three representative types of bioresorbable metal coronary drug-eluting stents (DESs) are reviewed, and the material composition, structural design, mechanical properties and degradability of iron-based, magnesium-based and zinc-based bioresorbable metal coronary DES are analyzed. The methods of regulating the radial strength and degradation rate of the coronary stents are summarized, and the/performance evaluation methods and ideal testing systems of the bioresorbable metal coronary DES are analyzed.

A Localized Scalable DNA Logic Circuit System Based on the DNA Origami Surface.

DNA (Deoxyribonucleic Acid) logic circuit systems provide a powerful arithmetic architecture for the development of molecular computations. DNA nanotechnology, particularly DNA origami, provides a nanoscale addressable surface for DNA logic circuit systems. Although molecular computations based on DNA origami surfaces have received significant attention in research, there are still obstacles to constructing localized scalable DNA logic circuit systems.

Effect of Structurally Modified Toluene Diisocyanate-Based Polyurethane Pads on Chemical Mechanical Polishing of 4H Silicon Carbide Substrate.

This study investigates the impact of polycarbonate diol (PCDL)-modified toluene diisocyanate (TDI)-based polyester polyurethane polishing pads on the chemical mechanical polishing of 4H silicon carbide (4H-SiC) substrates. Employing a unique metho, PCDL alters the ratio of polyurethane soft and hard segments, facilitating the one-step synthesis of a polishing pad via chemical foaming. The extent of the reaction of isocyanate groups was characterized by Fourier transform infrared spectroscopy, while the changes in the glass transition temperature of the material before and after modification were evaluated using differential scanning calorimetry.

Enhanced Piezoelectric Performance of Highly-Aligned ZnO Nanorods Embedded in P(VDF-TrFE) Nanofiber Membranes.

Flexible and wearable electronics often rely on piezoelectric materials, and Poly(vinylidene fluoride-trifluoroethylene) (P(VDF-TrFE)) membranes are popular for this application. However, their electromechanical performance is limited due to a relatively low piezoelectric coefficient. To address this, this study investigates the incorporation of zinc oxide (ZnO) nanorods (NRs) into a P(VDF-TrFE) nanofiber membrane matrix.