Effect of intraoperative mitomycin C application at different concentrations on corneal densitometry after SmartSurf transepithelial photorefractive keratectomy.

Purpose: This study aimed to investigate corneal densitometry (CD), visual, and refractive outcomes after transepithelial photorefractive keratectomy (TPRK) using smart pulse technology (SPT), known as the SmartSurface procedure, in patients treated with or without mitomycin C (MMC) at concentrations of 0.01% and 0.02%.

Cross-national differences in the association between estimated cardiorespiratory fitness and depressive symptoms among older adults: findings from three nationwide cohort studies.

Background: Cardiorespiratory fitness (CRF) is a modifiable risk factor for chronic diseases, but its association with depressive symptoms remains unclear, particularly across different populations. We aimed to investigate the link between estimated CRF (eCRF) and incident depressive symptoms among individuals over 50 years old, and to explore potential cross-country variations in this association.

Methods: Data were retrieved from three national cohorts: the Health and Retirement Study (HRS, United States), the English Longitudinal Study of Ageing (ELSA, England), and the China Health and Retirement Longitudinal Study (CHARLS, China).

The impact of age, gender, and ocular parameters on corneal biomechanics in Chinese refractive candidates.

We aimed to quantify the distribution of corneal biomechanics in healthy, myopic Chinese candidates for refractive surgery using an ocular response analyzer, and explore factors that influence corneal biomechanics. In this retrospective cross-sectional study, 1,090 eyes from 1090 myopic patients scheduled for refractive surgery at the Refractive Center of Dalian Third People's Hospital between January 2021 and May 2022 were examined. Participants were categorized into three groups based on spherical equivalent power: low myopia (SE> -3.

Vector analysis valuation of astigmatism in the cornea after femtosecond laser-assisted corneal astigmatism incision in cataract surgery.

Background: The aim of this article is to evaluate the effectiveness of anterior penetrating femtosecond laser-assisted astigmatism keratotomy (FS-AK) using vector analysis.

Methods: This retrospective before-after study included 68 patients with corneal astigmatism > 1D who underwent FLACS at Dalian Third People's Hospital between June 2023 and July 2024 as research participants. All patients received monofocal non-spherical intraocular lenses.

Knowledge mapping of posterior capsular opacification from 2011 to 2023: A bibliometric analysis.

This bibliometric analysis explores the current status and trends of global research on posterior capsular opacification (PCO). A search of the Web of Science Core Collection (WoSCC) database was conducted to identify publications on PCO from 2011 to 2023. Bibliometric analysis was used to explore publication trends in PCO-related research.

Non-inferiority trials in clinical ophthalmology: a systematic review.

Purpose: To summarize the characteristics and methodology of non-inferiority trials in ophthalmology, aiding researchers in understanding the applications and limitations of such trials in ophthalmic diseases.

Methods: PubMed, Web of Science, Embase and Scopus were searched for literature on non-inferiority randomized trials in ophthalmology published between 2000 and November 5 2023. Data on the basic characteristics were extracted and summarized.

[Progress in the therapy of corneal neovascularization].

Corneal neovascularization, a severe pathologic change of the ocular surface, is usually caused by complex pathogeneses, and leads to severe vision damage and eventually corneal blindness. The applications of anti-inflammatory and anti-angiogenic drugs as well as keratoplasty have proved to have certain therapeutic effects. However, there are still numerous barriers that have not yet been fully overcome, prompting a trend towards treatment with multidisciplinary techniques.

Management of delayed corneal epithelial healing after refractive surgery: five case reports.

Background: Transepithelial photorefractive keratectomy using Smart Pulse Technology (SPT-TransPRK) is currently the leading method for superficial refractive surgery, offering advantages such as a non-contact procedure, shorter operation times, and excellent patient cooperation. Laser ablation of the corneal epithelium, Bowman's membrane, and the stroma can effectively correct refractive errors. Thus, the complete healing of the corneal epithelium post-surgery is essential for ensuring good vision.

Analysis of the relevant factors for corneal graft rejection in the southern Liaoning region from 2019 to 2023.

Background: The study aimed to review the etiology of corneal blindness and investigate the relative risk of corneal graft rejection (CGR) in the southern Liaoning region.

Methods: The clinical records of 359 patients (394 eyes) who underwent corneal transplantation at the Department of Keratoconus of the Third People's Hospital of Dalian from January 2019 to December 2023 were retrospectively analyzed. The data included patients' age, gender, occupation, diagnosis, surgical procedure, postoperative immune rejection, and neovascularization.

Atypical conjunctival sporotrichosis secondary to Mooren's ulcer: a case report.

Background: Conjunctival sporotrichosis is a rare fungal infection, typically presenting as granulomatous lesions. Its manifestations can be atypical, particularly in immunosuppressed patients. Here, we present a rare case of a Mooren's ulcer patient with bulbar conjunctival Sporotrichosis presenting as a salmon-pink tumor.

Surface ablation laser surgery: Bibliometric and visualized analysis from 2004 to 2023.

Surface ablation laser surgery has resurged in popularity recently because of its safety in correcting myopia and favorable postoperative corneal biomechanical properties. This study aimed to investigate the current focal points and future trends in surface ablation laser surgery over the last 2 decades. The Web of Science Core Collection was used as the primary data source to retrieve literature related to surface ablation laser surgery.

Fighting against biofilm: The antifouling and antimicrobial material.

Biofilms are groups of microorganisms protected by self-secreted extracellular substances. Biofilm formation on the surface of biomaterial or engineering materials becomes a severe challenge. It has caused significant health, environmental, and societal concerns.

Drug-eluting contact lenses: Progress, challenges, and prospects.

Topical ophthalmic solutions (eye drops) are becoming increasingly popular in treating and preventing ocular diseases for their safety, noninvasiveness, and ease of handling. However, the static and dynamic barriers of eyes cause the extremely low bioavailability (<5%) of eye drops, making ocular therapy challenging. Thus, drug-eluting corneal contact lenses (DECLs) have been intensively investigated as a drug delivery device for their attractive properties, such as sustained drug release and improved bioavailability.

Causal relationships between height, screen time, physical activity, sleep and myopia: univariable and multivariable Mendelian randomization.

Background: This study aims to investigate the independent causal relation between height, screen time, physical activity, sleep and myopia.

Methods: Instrumental variables (IVs) for exposures and outcome were obtained from the largest publicly available genome-wide association studies (GWAS) databases. First, we performed a bidirectional univariate MR analysis using primarily the inverse variance weighted method (IVW) with height, screen time, physical activity and sleep as the exposure and myopia as the outcome to investigate the causal relationship between exposures and myopia.

Bibliometric and visualized analysis of posterior chamber phakic intraocular lens research between 2003 and 2023.

Introduction: Myopia is causing a major public health concern, with its prevalence increasing globally. This study aimed to discuss posterior chamber phakic intraocular lens (pIOL) research publication trends and hotspots over the past 20 years.

Methods: Bibliometric analysis was performed using the Web Science Core Collection to investigate posterior-chamber pIOL research publication trends.

Fourier analysis of corneal irregular astigmatism after small-incision lenticule extraction and transepithelial photorefractive keratectomy: A comparative study.

To compare changes in the spherical component, regular astigmatism, and irregular astigmatism of the anterior surface of the cornea after small-incision lenticule extraction (SMILE) and transepithelial photorefractive keratectomy (TransPRK). Fifty-six patients underwent SMILE in 56 eyes, and 68 patients underwet TransPRK in 68 eyes. The right eye was chosen to enter the group.

Observation of the effect of posterior scleral reinforcement combined with orthokeratology and 0.01% atropine in the treatment of congenital myopia: a case report.

Background: Myopia has recently emerged as a significant threat to global public health. The high and pathological myopia in children and adolescents could result in irreversible damage to eye tissues and severe impairment of visual function without timely control. Posterior scleral reinforcement (PSR) can effectively control the progression of high myopia by limiting posterior scleral expansion, improving retrobulbar vascular perfusion, thereby stabilizing the axial length and refraction of the eye.