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http://dx.doi.org/10.1016/j.celrep.2025.115692 | DOI Listing |
Carbohydr Polym
November 2025
College of Chemistry and Molecular Sciences, Key Laboratory of Biomedical Polymers of Ministry of Education, Wuhan University, Wuhan 430072, China. Electronic address:
Hemoperfusion is one of the most effective blood purification techniques to quickly remove bilirubin from the blood of patients with kidney or liver failure. Although numerous adsorbent materials with high adsorption capacity have been developed, their clinical application are still limited due to poor biocompatibility and biosafety issues. Herein, biocompatible core-shell structured adsorbents with cellulose microspheres (CMs) as the supporting core and phase-transformed lysozyme (PTL) as the functional shell are fabricated for the removal of bilirubin in hemoperfusion.
View Article and Find Full Text PDFFront Cell Infect Microbiol
September 2025
Department of Laboratory Medicine and Sichuan Provincial Key Laboratory for Human Disease Gene Study, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Objective: This hospital-based case-control study aims to evaluate hematological and biochemical markers for the diagnosis of cystic echinococcosis (CE) in the Tibetan population of Sichuan.
Methods: This study involved 83 patients diagnosed with CE and 45 healthy controls. Diagnosis of CE was confirmed through antibody and imaging tests, followed by an analysis of differences in blood and biochemical markers.
Aquat Toxicol
August 2025
State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining, 810001, China. Electronic address:
Microplastics (MPs) and antibiotics (ATs) accumulating in Qinghai Lake threaten aquatic health, yet their impact on Gymnocypris przewalskii (G.przewalskii) remains unclear.This multi-omics study investigated polypropylene MPs (PP-MPs) and sulfonamide antibiotics (SGD) on G.
View Article and Find Full Text PDFHaematologica
September 2025
Department of Biochemistry and Molecular Genetics, University of Colorado Denver - Anschutz Medical Campus, Aurora, CO, USA; Omix Technologies Inc, Aurora, CO.
Caffeine is the most widely consumed psychoactive substance globally, yet its peripheral physiological effects remain incompletely understood. Leveraging comprehensive data from 13,091 blood donors in the REDS RBC-Omics study, we identify caffeine as a significant modulator of red blood cell (RBC) storage quality and transfusion outcomes. Elevated caffeine levels were reproducible across multiple donations from 643 recalled donors, selected based on their extremes in hemolytic propensity.
View Article and Find Full Text PDFWorld J Gastroenterol
August 2025
Department of Infectious Diseases, The Hebei Medical University Third Hospital, Shijiazhuang 050000, Hebei Province, China.
Background: Acute-on-chronic liver failure (ACLF) is characterized by severe metabolic disturbances; however, the specific metabolomic features and their predictive value on 90-day prognosis remain unclear.
Aim: To identify serum metabolomic changes in patients with ACLF with different prognoses to support clinical prediction of outcomes and treatment decisions.
Methods: This non-interventional, observational case-control study enrolled 58 patients with ACLF.