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Article Abstract

In this study, BiCl-promoted and KSO-mediated synthesis of diverse bis-sulfonyl 2,6-diarypyridines was developed one-pot stepwise (2C + 2C + 1C + 1N) annulation of two molecules of β-ketosulfone and ,-dimethylacetamide (DMAC). In the entire process, DMAC acts as the synthon of one carbon and one nitrogen in the construction of the pyridine skeleton cascade formation of single (C-C/C-N) and double (CC/CN) bonds under refluxing DMAC conditions.

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http://dx.doi.org/10.1039/d4ob01681eDOI Listing

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