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Background: Endoscopic retrograde appendicitis therapy (ERAT) is a new method of treating acute appendicitis that has emerged in recent years in children, but the application of radiological examination in the diagnosis and treatment of pediatric diseases is greatly limited. Therefore, high-frequency ultrasonography imaging has attracted more and more attention because of its advantages such as non-invasiveness, no radiation, and a simpler procedure. This study aims to explore the application value of high-frequency ultrasonography in ERAT for pediatric acute appendicitis.
Methods: A retrospective analysis was conducted on 136 children admitted to our hospital from January 2020 to October 2021 who were definitively diagnosed with acute appendicitis and underwent endoscopic retrograde intra-appendiceal irrigation treatment under the guidance of high-frequency ultrasonography. They were divided into the preschool age group (< 6 years) and school age group (≥ 6 years) according to age. Before the operation and at 1-2 days after ERAT, the external diameter of the appendix, as well as the thickness of the intestinal wall, mucosal layer, and muscular layer in each group were measured by high-frequency ultrasonography and recorded in detail. During the operation, a stent was placed under real-time guidance, and the situation in the cavity was observed. The clinical data of the two groups of children before and after the operation were collected, and the recurrence status after treatment was followed up.
Results: Endoscopic treatment was completed in 131 patients with a success rate of 96.32%. There was no significant difference between the two groups in appendix diameter, intestinal wall, or muscular layer after the operation when compared to those before the operation (p > 0.05), but there was a significant difference in the mucosal thickness after operation when compared to before the operation (p < 0.05). Abdominal pain in the two groups was significantly relieved immediately after the operation, and the white blood cell count returned to normal, with a significant difference before and after the ERAT operation (p < 0.05).
Conclusion: Endoscopic intra-appendiceal irrigation under the guidance of high-frequency ultrasonography is a real-time and convenient method that is safe and effective in treating pediatric acute appendicitis.
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http://dx.doi.org/10.1007/s00464-022-09779-6 | DOI Listing |
Front Physiol
August 2025
School of Mechanical Engineering and IEDT, Kyungpook National University, Daegu, Republic of Korea.
Introduction: Quantitative computed tomography (qCT) provides detailed spatial assessments of lung structure and function, while electrical impedance tomography (EIT) offers high temporal resolution for analyzing breathing patterns but lacks structural detail. This study investigates the correlation between qCT-based spatial variables and EIT-based temporal signals to elucidate the physiological relationships between these two modalities.
Methods: Six participants with asthma underwent pulmonary function tests (PFTs) before and after bronchodilator inhalation.
J Eval Clin Pract
September 2025
Department of Orthopedics and Traumatology, Medical Faculty, University of Health Sciences, Antalya, Turkey.
Aims And Objective: The field of medical statistics has experienced significant advancements driven by integrating innovative statistical methodologies. This study aims to conduct a comprehensive analysis to explore current trends, influential research areas, and future directions in medical statistics.
Methods: This paper maps the evolution of statistical methods used in medical research based on 4,919 relevant publications retrieved from the Web of Science.
J Vis Exp
August 2025
Department of Oncology, Shanghai Medical College, Fudan University; Department of Ultrasound, Fudan University Shanghai Cancer Center;
The management of benign thyroid nodules has evolved significantly with the advent of minimally invasive techniques, offering patients effective alternatives to traditional surgery. Among these, radiofrequency ablation (RFA) and microwave ablation (MWA) have emerged as the leading modalities. RFA, the most widely adopted method, uses high frequency alternating current to induce thermal coagulation.
View Article and Find Full Text PDFTop Stroke Rehabil
August 2025
Department of Ultrasound, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Background: Little is known about the use of ultrasonography to evaluate lower-limb function during early stroke-induced hemiparesis rehabilitation.
Objective: To investigate the changes in structural and mechanical parameters using high-frequency ultrasonography to identify parameters correlating with functional improvement.
Methods: Forty-five patients with first-ever stroke within the past 6 months and unilateral lower-limb motor dysfunction were prospectively included.
Postgrad Med J
August 2025
Department of Dermatology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, No. 1678, Dongfang Road, Pudong New District, Shanghai, 200127, China.
Background: Pilomatricoma, albeit benign, may have a potential impact on children's appearance and health. Clinical practice has revealed variations in the clinical manifestations, anatomical locations, and sizes of pilomatricoma among different pediatric patients. However, few studies have comprehensively summarized the correlations between these features and treatment efficacy, which is crucial for enhancing clinicians' understanding and diagnostic accuracy of the disease.
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