Passively Ultra Cooling Patch Enabling High-Efficiency Power-Water Cogeneration.

Photovoltaic (PV) systems, which accounted for 75% of global renewable energy capacity in 2023, are limited by the substantial waste heat generated through the photothermal effect, reducing both electricity generation efficiency and panel longevity. In this work, a passive cooling strategy using an ultra-cooling patch (UCP) that effectively cools down the PV panel is presented, thus achieving an exceptionally high cooling power of nearly 700 W m and facilitating the recovery of over 70% of waste heat for freshwater production. The flexibility and adhesive properties of UCP allow for easy integration with various PV configurations, including flexible panels.

Vermicular Eutectic Multi-Principal Element Alloy with Exceptional Strength and Ductility.

Eutectic multi-principal element alloys (EMPEAs), with multiple main elements in compositions and eutectic microstructures, are considered promising high-performance materials for structural applications. The microstructure of EMPEAs usually exhibits a mixture of soft and hard phases in straight rod-like or lamellar morphology, which contribute to a balanced synergy of strength and ductility. However, such conventional morphology may also constrain the possible space for further improving their mechanical properties, and the question proposed is whether the straight morphology can be kinked to unlock a new space for achieving better mechanical properties.

Transforming Waste into Valuable Resources: MoC Nanoparticles Modified Waste Pinecone-Derived Carbon as an Effective Sulfur Host for Lithium-Sulfur Batteries.

In this paper, the natural waste pinecone as a carbon precursor for the generation of satisfactory sulfur host materials in lithium-sulfur batteries was realized by introducing molybdenum carbide nanoparticles into the derived carbon structure. The conductive pinecone-derived carbon doped with N, O reveals an expansive specific surface area, facilitating the accommodation of a higher sulfur load. Moreover, the integration of MoC nanoparticles also significantly enhances its chemical affinity and catalytic capacity for polysulfides (LiPSs) to alleviate the shuttle effect and accelerate sulfur redox conversion.

Post-TIPS Overt Hepatic Encephalopathy Increases Long-Term but Not Short-Term Mortality in Cirrhotic Patients With Variceal Bleeding: A Large-Scale, Multicenter Real-World Study.

Background: Transjugular intrahepatic portosystemic shunt (TIPS) is an established procedure for managing portal hypertension in cirrhotic patients, but the impact of post-TIPS overt hepatic encephalopathy (OHE) on survival remains controversial. While its effect on short-term survival is well-documented, its long-term implications remain unclear.

Aims: This study aims to investigate the long-term impact of post-TIPS OHE on mortality in cirrhotic patients for variceal bleeding, focusing on the timing and predictive value of OHE beyond the first year post-TIPS.

Simultaneous Salt Rejection and Heat Localization Via Engineering Macrochannels in Morning Glory-Shaped 3D Evaporator.

Solar desalination is a promising solution for alleviating water scarcity due to its low-cost, environmentally friendly, and off-grid capabilities. However, simultaneous salt rejection and heat localization remain challenging, as the rapid salt convection often results in considerable heat loss. Herein, this challenge is overcome via a facile design: i) isolating high-temperature and high-salt zones by rationally designing morning glory-shaped wick structures and ii) bridging high-salt zones and bulk water with low-tortuosity macrochannels across low-temperature surfaces.

Small Transjugular Intrahepatic Portosystemic Shunt Plus Variceal Embolization for Gastric Varices: A Multicenter Cohort Study.

Background & Aims: The effect of transjugular intrahepatic portosystemic shunt (TIPS) plus variceal embolization for treating gastric varices (GVs) remains controversial. This nationwide multicenter cohort study aimed to evaluate whether adding variceal embolization to a small diameter (8-mm) TIPS could reduce the rebleeding incidence in patients with different types of GVs.

Methods: This retrospective cohort study involved 629 patients who underwent 8-mm TIPS for gastric varices at 7 medical centers.

Risk factors for suspected pulmonary embolism in children: Complication of Mycoplasma pneumoniae pneumonia.

Purpose: Pulmonary embolism (PE) is not a rare complication of Mycoplasma pneumoniae pneumonia (MPP) in children. We sought to determine the incidence of PE in children with MPP who underwent clinically indicated CT pulmonary angiography (CTPA) and to evaluate the risk factors for PE.

Methods: All 106 children with MPP who were clinically suspected of having PE and who underwent CTPA were retrospectively enrolled from June 2018 to December 2021.

Amplified Assembly of G-Quadruplex-Decorated DNA Network Nanostructure toward AIE Signaling-Based Sensitive Biosensing.

Aggregation-induced emission (AIE) has offered a promising approach for developing low-background fluorescent methods; however, its applications often suffer from complex probe synthesis and poor biocompatibility. Herein, a novel AIE biosensing method for kanamycin antibiotic assays was developed by utilizing a DNA network nanostructure assembled from an aptamer recognition reaction to capture a large number of tetraphenylethylene fluorogen-labeled signal DNA (DTPE) probes. Due to the excellent hydrophilicity of the oligonucleotides, DTPE exhibited excellent water solubility without obvious background signal emission.

B3galt5 deficiency attenuates hepatocellular carcinoma by suppressing mTOR/p70s6k-mediated glycolysis.

Hepatocellular carcinoma (HCC) is one of the most common malignancies with high morbidity and mortality. Beta-1,3-galactosyltransferase 5 (b3galt5) plays crucial roles in protein glycosylation, but its function in HCC remains unclear. Here, we investigated the role and underlying mechanism of b3galt5 in HCC.

TMP195 Exerts Antitumor Effects on Colorectal Cancer by Promoting M1 Macrophages Polarization.

Studies have shown that epigenetic enzymes such as histone deacetylase (HDAC) are closely related to cancers and that several HDAC inhibitors exert antitumor effects. Studies have further suggested that class IIa HDAC inhibitors are related to immune functions, including immune responses and the expression of chemokines and complement pathway components. TMP195, a selective class IIa HDAC inhibitor, has been reported to be effective against breast cancer.

CD3CD4CD8 (Double-Negative) T Cells in Inflammation, Immune Disorders and Cancer.

The crucial role of CD4 and CD8 T cells in shaping and controlling immune responses during immune disease and cancer development has been well established and used to achieve marked clinical benefits. CD3CD4CD8 double-negative (DN) T cells, although constituting a rare subset of peripheral T cells, are gaining interest for their roles in inflammation, immune disease and cancer. Herein, we comprehensively review the origin, distribution and functions of this unique T cell subgroup.