Passivity and Synchronization for Fuzzy Coupled Reaction-Diffusion Neural Networks With Multiweights.

This article is concerned with passivity and synchronization for fuzzy coupled reaction-diffusion neural networks (FCRDNNs) with multistate couplings or multiple spatial-diffusion couplings. First, by utilizing an adaptive state feedback controller, several passivity criteria for the FCRDNNs with multistate couplings are obtained. Moreover, a sufficient condition to guarantee the synchronization for the multistate coupled FCRDNNs is also given on the basis of the devised adaptive state feedback control scheme.

Kidney supportive care in advanced chronic kidney disease: a qualitative meta-synthesis of healthcare professionals perspectives and attitudes.

Aims: This study systematically reviews and synthesizes healthcare professionals' perspectives on Kidney Supportive Care (KSC) to establish an evidence base for enhancing its clinical dissemination and implementation.

Background: KSC enhances end-of-life care quality for renal patients through a patient-centered framework integrating shared decision-making and advance care planning. This anticipatory transition management in advanced kidney disease seeks to alleviate patient/family distress while optimizing end-of-life care experiences.

Bipartite Synchronization for Coupled Fractional-Order Reaction-Diffusion Neural Networks With Multiple Weights.

This article deals with the bipartite synchronization in coupled fractional-order reaction-diffusion neural networks (CFRNN) with multiple state or multiple spatial diffusion couplings. A bipartite synchronization condition is derived for the multiple state CFRNN (MSCFRNN) with the help of the Lyapunov functional combined with inequality techniques, and an adaptive state-feedback control scheme is also devised to ensure the bipartite synchronization of the MSCFRNN. Similarly, several sufficient conditions are also given to guarantee the bipartite synchronization in the multiple spatial diffusion CFRNN (MSDCFRNN).

Placebo response in sham acupuncture therapy trials for simple obesity: A systematic review and meta-analysis.

Background: Acupuncture has shown potential therapeutic benefits for individuals with simple obesity. However, some researchers argue that some of the effectiveness of acupuncture may be due to the placebo response.

Objective: To understand the placebo response of acupuncture treatment in simple obesity, a systematic review and meta-analysis was designed based on the comparison between sham acupuncture before and after treatment.

Development and Validation of Ultrasound Hemodynamic-based Prediction Models for Acute Kidney Injury After Renal Transplantation.

Rationale And Objectives: Acute kidney injury (AKI) post-renal transplantation often has a poor prognosis. This study aimed to identify patients with elevated risks of AKI after kidney transplantation.

Materials And Methods: A retrospective analysis was conducted on 422 patients who underwent kidney transplants from January 2020 to April 2023.

Cloning, Expression, and Functional Characterization of three 6-hydroxyalizarin Glycosyltransferases from Rheum palmatum.

Glycosyltransferases are key enzymes responsible for the glycosylation of natural products in plants. The roots and rhizomes of Rheum palmatum Diels, commonly known as rhubarb, are well-established in traditional Chinese medicine and are rich in diverse glycoside natural products. Despite this, no glycosyltransferase from R.

TfO/DMSO-Promoted Umpolung Phosphorylation for C(sp)-P or C(sp)-P Bond Formation.

We have developed an umpolung method utilizing the TfO/DMSO-based system for C(sp)-P bond or C(sp)-P bond formation. This method employs both P(O)-H and P(O)-OH compounds as phosphorus sources and demonstrates excellent compatibility with a wide range of Grignard reagents. Without the requirement of precious transition metals or additives, this one-pot protocol provides a practical and efficient synthetic pathway to a variety of aryl and alkyl phosphine oxides.

Land cover classification of high-resolution remote sensing images based on improved spectral clustering.

Applying unsupervised classification techniques on remote sensing images enables rapid land cover classification. Using remote sensing imagery from the ZY1-02D satellite's VNIC and AHSI cameras as the basis, multi-source feature information encompassing spectral, edge shape, and texture features was extracted as the data source. The Lanczos algorithm, which determines the largest eigenpairs of a high-order matrix, was integrated with the spectral clustering algorithm to solve for eigenvalues and eigenvectors.

OAB-14 alleviates mitochondrial impairment through the SIRT3-dependent mechanism in APP/PS1 transgenic mice and N2a/APP cells.

Alzheimer's disease (AD) is a progressive degenerative disease that affects a growing number of elderly individuals worldwide. OAB-14, a novel chemical compound developed by our research group, has been approved by the China Food and Drug Administration (FDA) for clinical trials in patients with AD (approval no. YD-OAB-220210).

Optimized Machine Learning Model for Predicting Compressive Strength of Alkali-Activated Concrete Through Multi-Faceted Comparative Analysis.

Alkali-activated concrete (AAC), produced from industrial by-products like fly ash and slag, offers a promising alternative to traditional Portland cement concrete by significantly reducing carbon emissions. Yet, the inherent variability in AAC formulations presents a challenge for accurately predicting its compressive strength using conventional approaches. To address this, we leverage machine learning (ML) techniques, which enable more precise strength predictions based on a combination of material properties and cement mix design parameters.

Advancements in enzymatic reaction-mediated microbial transformation.

Enzymatic reaction-mediated microbial transformation has emerged as a promising technology with significant potential in various industries. These technologies offer the ability to produce enzymes on a large scale, optimize their functionality, and enable sustainable production processes. By utilizing microbial hosts and manipulating their genetic makeup, enzymes can be synthesized efficiently and tailored to meet specific industrial requirements.

Stimulation of an entorhinal-hippocampal extinction circuit facilitates fear extinction in a post-traumatic stress disorder model.

Effective psychotherapy of post-traumatic stress disorder (PTSD) remains challenging owing to the fragile nature of fear extinction, for which the ventral hippocampal CA1 (vCA1) region is considered as a central hub. However, neither the core pathway nor the cellular mechanisms involved in implementing extinction are known. Here, we unveil a direct pathway, where layer 2a fan cells in the lateral entorhinal cortex (LEC) target parvalbumin-expressing interneurons (PV-INs) in the vCA1 region to propel low-gamma-band synchronization of the LEC-vCA1 activity during extinction learning.

The CYP3A inducer dexamethasone affects the pharmacokinetics of sunitinib by accelerating its metabolism in rats.

Sunitinib, a novel anti-tumor small molecule targeting VEGFR, is prescribed for advanced RCC and GISTs. Sunitinib is primarily metabolized by the CYP3A enzyme. It is well-known that dexamethasone serves as a potent inducer of this enzyme system.

Up-regulating GABA transporter-3 in the zona incerta prevents surgery-induced memory impairment in mice.

Clinical surgery can lead to severe neuroinflammation and cognitive dysfunctions. It has been reported that astrocytes mediate memory formation and postoperative cognitive dysfunction (POCD), however, the thalamic mechanism of astrocytes in mediating POCD remains unknown. Here, we report that reactive astrocytes in zona incerta (ZI) mediate surgery-induced recognition memory impairment in male mice.

Comparison of three-dimensional heads-up system versus traditional microscopic system in medical education for vitreoretinal surgeries: a prospective study.

Background: To compare the value and efficiency of the three-dimensional (3D) heads-up surgical system and traditional microscopic (TM) system in teaching and learning vitreoretinal surgeries.

Methods: Twenty ophthalmologists and scrub nurses were recruited as teachers, and 45 junior ophthalmology residents and trainee doctors, trainee nurses, and medical students were recruited as observers. Each teacher and observer were assigned to both a 3D-assisted and TM-assisted vitreoretinal surgery and then asked to complete satisfaction questionnaires for both surgical systems at the end of each surgery.

Central and Peripheral Changes in Retinal Vein Occlusion and Fellow Eyes in Ultra-Widefield Optical Coherence Tomography Angiography.

Purpose: To explore the central and peripheral retinal and choroidal changes in retinal vein occlusion (RVO) and fellow eyes using ultra-widefield swept-source optical coherence tomography angiography (UWF-SS-OCTA).

Methods: Fifteen ischemic central RVO (CRVO), 15 branch RVO (BRVO), and 15 age-matched healthy controls were prospectively recruited. Retinal and choroidal parameters, including retinal vessel flow density (VFD) and vessel linear density (VLD), choroidal vascularity volume (CVV), choroidal vascularity index (CVI), and VFD in the large and medium choroidal vessels (LMCV-VFD), were measured in the central and peripheral regions of the 24 × 20-mm UWF-SS-OCTA images.

Glutamatergic Projection from the Ventral Tegmental Area to the Zona Incerta Regulates Fear Response.

Innate defensive behavior is important for animal survival. The Vglut neurons in the ventral tegmental area (VTA) have been demonstrated to play important roles in innate defensive behaviors, but the neural circuit mechanism is still unclear. Here, we find that VTA - zona incerta (ZI) glutamatergic projection is involved in regulating innate fear responses.

Impacts of angiotensin II on retinal artery changes in apolipoprotein E deficient mice.

Aim: To investigate the impacts of angiotensin II (Ang II) on retinal artery changes in apolipoprotein E deficient () mice.

Methods: male mice were infused by minipumps with Ang II at 1000 ng/kg·min (Ang II group) or saline (control group) for 28d. They were underwent ophthalmic fundus examination on day 0, 14, and 28 of infusion.

[Quality of moxa with different leaf-to-moxa ratios based on correlation analysis of thermogravimetric properties, cellulose content, and microscopic characteristics of non-secretory trichomes].

The quality of moxa is a key factor affecting the efficacy of moxibustion. Traditional moxa grades are evaluated by the leaf-to-moxa ratio, but there is a lack of support from scientific data. Scanning electron microscopy(SEM), Image Pro Plus, Van Soest method, and stimultaneous thermal analysis(TGA/DSC) were used to characterize the scientific implication of the combustion differences between moxa with different leaf-to-moxa ratios(processed by crusher).

Abrogation of ATR function preferentially augments cisplatin-induced cytotoxicity in PTEN-deficient breast cancer cells.

Targeting replication stress response is currently emerging as new therapeutic strategy for cancer treatment, based on monotherapy and combination approaches. As a key sensor in response to DNA damage, ataxia telangiectasia and rad3-related (ATR) kinase has become a potential therapeutic target as tumor cells are to rely heavily on ATR for survival. The tumor suppressor phosphatase and tensin homolog (PTEN) plays a crucial role in maintaining chromosome integrity.

The incidence, risk factors, management and prognosis of postoperative systemic complications after ophthalmic surgery: a retrospective study at a tertiary, academic referral hospital over a decade.

Purpose: To explore the incidence, risk factors, management and prognosis of systemic complications after ophthalmic surgeries.

Methods: A retrospective review of hospitalized patients undergoing ophthalmic surgeries between 2012 and 2022 at Peking Union Medical College Hospital was performed to summarize and analyse the postoperative systemic complications. Multivariate logistic and linear regression analyses were conducted to clarify the risk factors of postoperative systemic complications and factors associated with the severity of adverse events.

[Spatial-temporal Changes and Driving Factors of Soil Microbial Communities in a Typical City of North China Plain].

The structure and function of microbial communities are affected by several environmental factors. To clarify the spatial-temporal changes and main influencing factors of soil microbial communities in a typical pharmaceutical city, it is urgent to study the spatial-temporal changes in microbial communities in soils for typical cities. Shijiazhuang City was selected as the study area, and 12 sampling sites were selected.

[Source Apportionment and Source-specific Risk of Typical Antibiotics in Baiyangdian Lake].

The current situation of antibiotic pollution in lakes is critical. At present, most of the previous studies on antibiotics in lakes have focused on the spatiotemporal distribution and risk assessment, while less attention has been paid to the source apportionment. Ultra-high performance liquid chromatography-mass spectrometry was used to determine the concentration of tetracyclines (TCs), sulfonamides (SAs), and quinolones (QNs) in the samples.