Improvement of gel quality and emulsion stability of high-dose gallic acid-modified myofibrillar protein by zein nanosystems: emphasizing the role of anionic polysaccharides.

The binding of high-dose polyphenols can induce aggregation of myofibrillar protein (MP), which compromises its gelling and emulsifying functionalities. Herein, zein/anionic polysaccharide nanoparticles were fabricated for efficient encapsulation of gallic acid (GA), to inhibit the excessive modification of MP by GA (180 μM/g). The GA encapsulation hindered the aggregation of MP, facilitating more proteins to participate in the construction of a denser and strengthened gel network with more entrapped water, and promoting the diffusion of the proteins to the oil surface, resulting in a lower interfacial tension and a more uniform droplet distribution.

Relationship between coronary artery calcification and plaque vulnerability, a qualitative and quantitative optical coherence tomography study.

Background: Coronary artery calcification (CAC) is an established hallmark of advanced atherosclerosis. The detailed relationship between CAC and plaque vulnerability remains incompletely understood. We aim to investigate the relationship between calcification burden, calcification patterns, and plaque instability features.

Electrocardiographic and clinical predictors for in-hospital mortality in patients with acute myocardial infarction caused by left main coronary artery occlusion.

The data on prediction for early mortality in patients with acute myocardial infarction (AMI) caused by total left main (LM) occlusion are limited. We aim to evaluate predictors for early mortality in these extremely high-risk patients. In this retrospective study, all consecutive patients with total occlusive LM-AMI were included between January 1997 and October 2023.

The relationships between inflammatory biomarkers, plaque characteristics, and macrophage clusters in coronary plaque: a quantitative assessment of macrophages based on optical coherence tomography.

Background: Quantitative assessment of macrophage accumulation is appealing in evaluating plaque inflammation. In optical coherence tomography (OCT) imaging, local macrophage clusters may be a feasible marker for macrophage quantification.

Methods: 404 patients presenting with acute coronary syndrome who underwent OCT evaluation were included.

Engineered cyanobacteria for improving poly-β-hydroxybutyrate production under NaHCO treatment.

Three engineered Synechocystis sp. PCC6803 strains, the OEphaAB (OE) strain, HEphaCAB (HE) strain, and HOphaAB-phaCAB (HO) strain, were constructed by overexpressing native and/or exogenous gene fragments to enhance the PHB synthesis. These strains exhibited a slight reduction in growth compared to the wild-type (WT) algae.

YOLO-SDD: An Effective Single-Class Detection Method for Dense Livestock Production.

Single-class object detection, which focuses on identifying, counting, and tracking a specific animal species, plays a vital role in optimizing farm operations. However, dense occlusion among individuals in group activity scenarios remains a major challenge. To address this, we propose YOLO-SDD, a dense detection network designed for single-class densely populated scenarios.

Enhancing realism in LiDAR scene generation with CSPA-DFN and linear cross-attention via Diffusion Transformer model.

Point cloud diffusion models have found extensive applications in autonomous driving and robotics. However, there is still a big gap between their generated LiDAR scene samples and real-world data in terms of visual quality. This discrepancy primarily arises from the loss of detailed information during the decoding process from latent space and the lack of guidance from global 3D structural information in the point cloud generation process, leading to distortions and artifacts in LiDAR scene samples.

The association between weight-adjusted waist index and respiratory symptoms in U.S adults: A national cross-sectional study.

Objective: This study aimed to evaluate the relationship between the weight-adjusted waist index (WWI) and respiratory symptoms, including cough, wheezing, and dyspnea, as well as the related respiratory diseases, namely chronic obstructive pulmonary disease (COPD) and asthma, in adults.

Methods: This cross-sectional study included 14,760 adults aged over 40 years, drawn from the National Health and Nutrition Examination Survey (NHANES) conducted between 2003 and 2012. Weighted logistic regression analysis was employed to investigate the association between WWI and respiratory symptoms, including cough, wheezing, and dyspnea, as well as related respiratory diseases such as COPD and asthma.

Restoring tumor antigenicity activates the "bystander" T cell immune cycle.

Tumor-specific T cells play a crucial role in tumor immunity. However, these cells are often scarce and functionally exhausted within the tumor microenvironment (TME), leading to the limited efficacy of immunotherapy in many cancer patients. In contrast, increasing evidence suggests that the TME is rich in "bystander" T cells (T), most of which are virus-specific and unrelated to the tumor.

Ferroptosis genes and ST-segment elevation myocardial infarction outcomes: A predictive signature.

Objective: The aim of this paper is to discover differentially expressed genes related to ferroptosis (DEFRGs) in patients with ST-segment elevation myocardial infarction (STEMI) and to construct a reliable prognostic signature that incorporates key DEFRGs and easily accessible clinical factors.

Methods: We did a systematic review of Gene Expression Omnibus datasets and picked datasets SE49925, GSE60993, and GSE61144 for analysis. We applied GEO2R to find DEFRGs and overlapped them among the picked datasets.

Proprotein convertase subtilisin/kexin type 9 inhibitors protect against contrast-associated acute kidney injury in patients with atherosclerotic cardiovascular disease.

Background And Aims: Contrast-associated acute kidney injury (CA-AKI) may occur in patients undergoing medical procedures involving x-rays and radiocontrast media, potentially resulting in prolonged renal impairment. However, no effective treatments are available. Therefore, this study aimed to investigate the efficacy of evolocumab, a proprotein convertase subtilisin/kexin type 9 inhibitor, in reducing CA-AKI incidence among patients with atherosclerotic cardiovascular disease (ASCVD) undergoing percutaneous coronary intervention.

Empagliflozin protects against heart failure with preserved ejection fraction partly by inhibiting the senescence-associated STAT1-STING axis.

Heart failure with preserved ejection fraction (HFpEF) is a mortal clinical syndrome without effective therapies. Empagliflozin (EMPA) improves cardiovascular outcomes in HFpEF patients, but the underlying mechanism remains elusive. Here, mice were fed a high-fat diet (HFD) supplemented with L-NAME for 12 weeks and subsequently intraperitoneally injected with EMPA for another 4 weeks.

Deconvolution Enhancement Keypoint Network for Efficient Fish Fry Counting.

Fish fry counting has been vital in fish farming, but current computer-based methods are not feasible enough to accurately and efficiently calculate large number of fry in a single count due to severe occlusion, dense distribution and the small size of fish fry. To address this problem, we propose the deconvolution enhancement keypoint network (DEKNet), a method for fish fry counting that features a single-keypoint approach. This novel approach models the fish fry as a point located in the central part of the fish head, laying the foundation for our innovative counting strategy.

Unsupervised Sentence Representation Learning with Frequency-induced Adversarial tuning and Incomplete sentence filtering.

Pre-trained Language Model (PLM) is nowadays the mainstay of Unsupervised Sentence Representation Learning (USRL). However, PLMs are sensitive to the frequency information of words from their pre-training corpora, resulting in anisotropic embedding space, where the embeddings of high-frequency words are clustered but those of low-frequency words disperse sparsely. This anisotropic phenomenon results in two problems of similarity bias and information bias, lowering the quality of sentence embeddings.

High-temperature molecular line list of hydroboron monoxide (HBO).

Hydroboron monoxide (HBO) is expected to occur in envelopes of the asymptotic giant branch (AGB), but a lack of spectroscopic data is hampering its possible detection. Using the state-of-the-art method, we present the first, comprehensive molecular line list for HBO which is suitable for temperatures up to = 3000 K. This new line list covers the wavenumber range of 0-9000 cm (wavelengths of ≥ 1.

Pivotal Impact Factors in Photocatalytic Reduction of CO to Value-Added C and C Products.

Over the past decades, CO greenhouse emission has been considerably increased, causing global warming and climate change. Indeed, converting CO into valuable chemicals and fuels is a desired option to resolve issues caused by its continuous emission into the atmosphere. Nevertheless, CO conversion has been hampered by the ultrahigh dissociation energy of C=O bonds, which makes it thermodynamically and kinetically challenging.

An Improved Method for Broiler Weight Estimation Integrating Multi-Feature with Gradient Boosting Decision Tree.

Broiler weighing is essential in the broiler farming industry. Camera-based systems can economically weigh various broiler types without expensive platforms. However, existing computer vision methods for weight estimation are less mature, as they focus on young broilers.

LaenNet: Learning robust GCNs by propagating labels.

Graph Convolutional Networks (GCNs) can be acknowledged as one of the most significant methodologies for graph representation learning, and the family of GCNs has recently achieved great success in the community. However, in real-world scenarios, the graph data may be imperfect, e.g.

Role of serum CAP1 protein in the diagnosis of patients with first-time acute myocardial infarction.

The dysregulation of adenylate cyclase-associated protein 1 (CAP1) is associated with a variety of inflammatory conditions. Here, we aimed to assess the role of serum CAP1 protein in predicting acute myocardial infarction (AMI), and to explore its effect and mechanism in vascular endothelial cells injury. ELISA was utilized to detected CAP1 protein expression in serum from 70 patients with first-time AMI at 0, 6, 12, 24, 48 hours and 7 days of the onset of chest pain.

In-hospital changes in the red blood cell distribution width and mortality in critically ill patients with heart failure.

Aims: A high red blood cell distribution width (RDW) at admission or discharge is associated with a worse prognosis in hospitalized patients with heart failure (HF), and the prognostic value of the in-hospital change in RDW (∆RDW) remains debatable.

Methods And Results: We included 5514 patients with critical illness and HF from the MIMIC-IV database. The ΔRDW was calculated by the RDW at discharge minus that at admission.