Microbiologic analysis of 140 patients undergoing revision total knee arthroplasty due to periprosthetic joint infection and aseptic loosening: droplet digital PCR analysis.

Objective: The primary reasons for postoperative joint prosthesis revision after total knee arthroplasty (TKA) are periprosthetic aseptic prosthesis loosening and joint infection (PJI). The objective of this study is to analyze the predominant microbial species responsible for PJI while also discussing was related.

Methods: A retrospective analysis was conducted on patients who underwent TKA revision surgery for the treatment of PJI and aseptic loosening of joint prostheses at our institution.

Study on the structure characterisation and swelling properties of the CMSM.

In order to further understand the potential applications of cellulose membrane materials in adsorption, drug delivery, and biomedical applications, to optimise their material properties, improve their performance, and expand their application fields, carboxymethyl Salix powder (CMS) was prepared by etherification reaction using Salix powder (SPP) as the raw material. Carboxymethyl Salix powder membrane (CMSM) was subsequently prepared through wet spinning technology. The swelling properties of CMSM were investigated.

Cluster structure evolution in binary TMS-HO/DO mixtures: Insights into molecular interactions.

The hydrogen bonding network of tetramethylene sulfone (TMS)-water/heavy water binary solutions with different volume ratios was investigated using spontaneous and stimulated Raman spectra. The results indicate that, as the concentration of V increases, TMS does not engage in hydrogen bonding with water or heavy water. However, it influences the system by altering the molecular clustering of water and heavy water.

MXene-Based Microneedle Electrode for Brain-Computer Interface in Diverse Scenarios.

In this study, we introduce a brain-computer interface (BCI) framework incorporating MXene microneedle EEG electrodes, tailored for versatile deployment. The dry electrodes, configured as 1 mm microneedles, underwent meticulous processing to establish a cohesive integration with the MXene conductive material. The microneedle architecture facilitates epidermal penetration, yielding low contact impedance, enabling the recording of spontaneous EEG and induced brain activity, and ensuring high precision in steady-state visual evoked potential (SSVEP) speller.

Hydrogen bonding state of THF-HO solution analyzed by 2D Raman-COS spectroscopy.

In this study, three distinct hydrogen bonding (HB) states of tetrahydrofuran (THF)-aqueous solutions at varying concentrations were characterized and analyzed using Raman spectroscopy coupled with two-dimensional correlation Raman (2D-COS) analysis. Specifically, in the range of 10%≤N≤ 30%, the solution exhibits cluster structures characterized by free THF-5HO and THF-4HO tetrahedral configurations; in the range of 40%≤N≤ 70%, the cluster structures within the solution consisted of THF·2HO and THF·HO configurations, following the fragmentation of tetrahedral structures; in 80%≤N the disruption of the tetrahedral structure of water enters the second stage, resulting in the formation of 2THF·HO and low-dimensional self-aggregated structures of THF. Combined with density functional theory, a further discussion on the changes in bond lengths and bond angles was conducted.

A new way to combine carboxymethyl cellulose with Fe: Application and mechanism analysis.

A new, effective powdered adsorbent (CMCFe) for removing oxytetracycline (OTC) was synthesized successfully in an acidic environment using a thermal fusion technique. CMC-Fe underwent comprehensive SEM, EDS, FT-IR, XRD, XPS, TGA, and BET analyses before and after adsorbing OTC. These studies systematically examined preparation variables such as CMC and FeCl ratios, acetic acid quantity, reaction duration, and temperature.

Ultrasensitive detection of SCCA employing a graphene oxide integrated microfiber ring laser biosensor.

Squamous cell carcinoma antigen (SCCA) is one of the most commonly detected cancer biomarkers for a variety of cancers. In this paper, a microfiber ring laser biosensor with a graphene oxide linking layer for SCCA detection was proposed and experimentally demonstrated. SCCA antibody immobilized on graphene oxide surface binds specifically to SCCA, and induces refractive index variation over the surface of the microfiber biosensor, which leads to a wavelength shift of the microfiber ring laser biosensor.

Preparation and Selective Adsorption Performance of the Carboxymethyl Salix psammophila Wood Powder-Imprinted Membrane for Tetracycline.

Carboxymethyl wood powder-imprinted membranes (CMSM-MIPs) were prepared by using wet spinning technology and molecular-imprinting technology for the selective removal of tetracycline from wastewater. Scanning electron microscopy, X-ray diffraction, thermogravimetry, and X-ray photoelectron spectroscopy characterizations demonstrate that CMSM-MIPs retain the membranous structure of Carboxymethyl wood powder membranes, successfully encapsulate thin layers of imprinted polymers on the membrane surface, and exhibit excellent thermal stability. The adsorption results showed that CMSM-MIPs had the highest selective adsorption capacity for tetracycline, which was 253.

Efficacy analysis of clinical serological indicators in the diagnosis of postoperative periprosthetic joint infection in patients with rheumatoid arthritis or osteoarthritis.

Purpose: To investigate the incidence of periprosthetic joint infection (PJI) in patients with rheumatoid arthritis (RA) or osteoarthritis (OA) after primary joint arthroplasty; to analyze the optimal cut-off values of clinical serum markers C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and D-dimer for the diagnosis of PJI in RA patients; and to explore their diagnostic efficacy and clinical significance.

Methods: Clinical data of 15,702 patients with RA (578) or OA (15,124) who underwent total joint arthroplasty from 2013 to 2021 were retrospectively analyzed. Serum CRP, ESR, and D-dimer were recorded for each patient, and subject characteristic curves were used to determine the optimal threshold values of CRP, ESR, and D-dimer for RA-PJI and OA-PJI and to compare the areas under the curves to assess the diagnostic efficacy of the optimal threshold values of serologic indices for RA-PJI.

Adsorption performance of ammonium molybdate modified Salix wood flour biochar for the treatment of monosodium glutamate wastewater.

The problem of wastewater pollution in the production of monosodium glutamate (MSG) is becoming more and more serious. A novel type of chemically modified Salix psammophila powder charcoal (SPPC) was synthesized to address the chemical oxygen demand (COD) and ammonia nitrogen (NH-N) in MSG wastewater. SPPC was prepared by carbonization method, in which inorganic ammonium molybdate (AM) was used as modifier and Salix psammophila powder (SPP) was used as raw material.

Study on the structure characterization and swelling properties of the FeO/CMS composite membrane.

In order to improve the functionality of cellulosic materials research and development of high performance soluble materials. Therefore, the FeO/CMS composite membrane was prepared by using carboxymethyl salix powder (CMS) and FeO as raw materials, 1-propenyl-3-methylimidazolium chloride and dimethyl sulfoxide as dissolution system. The effects of swelling time, swelling temperature, pH and ionic strength on the swelling performance of FeO/CMS composite membranes and the swelling kinetics of the composite membranes were studied.

Exploring the dynamic changes in hydrogen bond structure of water and heavy water under external perturbation of DMF.

The Raman spectra of DMF-water/heavy water binary solutions at different volume ratios are measured to investigate the hydrogen bond structure between N, N-dimethylformamide (DMF) and water/heavy water. It was observed that when V below 40 %, DMF reinforces the hydrogen bond among water molecules through the substitution of a small amount of water molecules within the tetrahedral structure. However, a similar enhancement phenomenon is not observed in heavy water.

Enhancement of stimulated Raman scattering of a weak vibration mode in tetrahydrofuran through the energy-transfer resonance of lycopene.

A method of energy-transfer resonance of lycopene used to enhance stimulated Raman scattering (SRS) of a weak vibration C-O mode in tetrahydrofuran (THF) was developed in this study. Only C-H SRS was observed in pure THF at high energies. When lycopene was added, the C-O SRS located at 915 cm of the weak vibration mode in THF was observed.

D-shaped photonic crystal fiber sensor based on the surface plasmon resonance effect for refractive index detection.

In this paper, a photonic crystal fiber (PCF) sensor based on the surface plasmon resonance (SPR) effect for refractive index (RI) detection is proposed. We design a D-shaped polished PCF structure consisting of air holes arranged in a hexagonal lattice. The silver film is coated on the middle channel of the polished surface of the PCF.

Effect of lignocellulose/montmorillonite immobilized Bacillus sp. on monosodium glutamate wastewater.

A group of Bacillus sp. was extracted from monosodium glutamate wastewater. Lignocellulose/montmorillonite composite was selected as the carrier.

Pose and Color-Gamut Guided Generative Adversarial Network for Pedestrian Image Synthesis.

Tremendous transfer requirements in pedestrian reidentification (Re-ID) tasks have greatly promoted the remarkable success in pedestrian image synthesis, to relieve the inconsistency in poses and lighting. However, existing approaches are confined to transferring in a particular domain and are difficult to combine, since pose and color variables locate in two independent domains. To facilitate the research toward conquering this issue, we propose a pose and color-gamut guided generative adversarial network (PC-GAN) that performs joint-domain pedestrian image synthesis conditioned on certain pose and color-gamut through a delicate supervision design.

Study on the cyclic adsorption performance of biomass composite membrane for Hg(II).

(SPPM) with high adsorption capacity and good cycle adsorption performance was prepared by wet spinning technology. The SPPM was characterised by the scanning electron microscope (SEM), specific surface area test (BET), energy dispersive spectrum (EDS) thermal gravimetric analysis (TGA), fourier transform infrared spectroscopy (FT-IR), and x-ray photoelectron spectroscopy (XPS). The results showed that the surface of SPPM is rough and porous, with good pore structure and thermal stability, and mercury ions (Hg(II)) have been successfully adsorbed on SPPM.

Uptake of iron oxide nanoparticles inhibits the photosynthesis of the wheat after foliar exposure.

Iron oxide nanoparticles (nFeO)-filled materials have been widely employed in various products and their effects on plants have attracted considerable attention because of their potential release into the environment. Currently, numerous studies reporting the influences of iron-bearing nanoparticles on plants are focused on root or seed exposure. However, plants exposed to atmospheric iron-bearing nanoparticles through the leaves and their impacts on plants are still not well understood.

Intramedullary Nailing Versus Minimally Invasive Plate Osteosynthesis for Distal Tibial Fractures: A Systematic Review and Meta-Analysis.

To evaluate the application, safety and efficacy of the patients treated with intramedullary nailing (IMN) and minimally invasive plate osteosynthesis (MIPO) in distal tibia fractures. Following the Preferred Reporting Items for Systematic Reviews and Meta Analysis (PRISMA) guidelines, we searched databases PubMed, Cochrane library, EMBASE and Web of Science from inception of the database up to 10 October 2018, using the keywords "distal tibia fractures", "plate", "intramedullary nailing" and "RCT" to identify randomized clinical trials about distal tibia fractures. The included studies were assessed by two researchers according to the Cochrane risk-of-bias criteria.

Metallothionein-1 suppresses rheumatoid arthritis pathogenesis by shifting the Th17/Treg balance.

It is now well accepted that an imbalance between the Th17 and regulatory T-cell responses is closely associated with the development of rheumatoid arthritis (RA). However, the precise regulatory mechanism for the differentiation of Th17 and Treg in RA is not well characterized. The present study showed that metallothionein-1 (MT-1), which is a low molecular weight protein that is involved in the detoxification of heavy metals and scavenging of free radicals, was upregulated in RA.

Notoginsenoside R7 suppresses cervical cancer via PI3K/PTEN/Akt/mTOR signaling.

Notoginsenoside R7 was isolated from , a plant used commonly in traditional Chinese medicine. We investigated the anti-cancer effects of R7 in HeLa cells and , and explored the underlying mechanisms of action. R7 dose-dependently inhibited HeLa cell proliferation and induced apoptosis , docking-based screening assays showed that R7 can directly bind Akt.

IL-37 is associated with osteoarthritis disease activity and suppresses proinflammatory cytokines production in synovial cells.

The objective of this study is to investigate the correlation between IL-37 level and osteoarthritis activity and to determine the anti-inflammatory effects of IL-37 in peripheral blood mononuclear cells (PBMCs) and synovial cells (SCs) from osteoarthritis (OA) patients, which including 32 patients with erosive inflammatory OA (EIOA) and 40 patients with primary generalized OA (PGOA), 40 age and sex matched healthy volunteers were recruited as healthy controls (HCs). The protein and relative mRNA levels of IL-37 were significant increased in the blood of EIOA patients compared with those of PGOA patients and HCs. Serum IL-37 levels of OA patients were positively correlated with VAS score, as well as with CRP, ESR in blood.

Functional and transcriptomic analysis of the key unfolded protein response transcription factor HacA in Aspergillus oryzae.

HacA is a conserved basic leucine zipper transcription factor that serves as the master transcriptional regulator in the unfolded protein response (UPR). To comprehensively evaluate the role of HacA in Aspergillus oryzae, a homokaryotic hacA disruption mutant (HacA-DE) and a strain that expressed a constitutively active form of HacA (HacA-CA) were successfully generated, and transcriptome analyses of these mutants were performed. Growth and phenotypic profiles demonstrated that hyphal growth and sporulation were impaired in the HacA-DE and HacA-CA strains that were grown on complete and minimal media, and the growth impairment was more pronounced for the HacA-CA strain.

Interleukin-37 is increased in ankylosing spondylitis patients and associated with disease activity.

Background: Interleukin-37 (IL-37) has been known to play an immunosuppressive role in various inflammatory disorders, but whether it participates in the regulation of pathogenesis of ankylosing spondylitis (AS) has not been investigated. Here, we examined the serum levels of IL-37 and its clinical association in AS, and explored the anti-inflammatory effects of IL-37 on peripheral blood mononuclear cells (PBMCs) from AS patients.

Methods: The mRNA levels of IL-37, TNF-α, IL-6, IL-17, and IL-23 in PBMCs and their serum concentrations from 46 AS patients were examined by real-time polymerase chain reaction (RT-PCR) and enzyme-linked immunoassay (ELISA), respectively.