Temperature-dependent transformation of piggery biogas residue pyrolysis products: Balancing resource recovery and environmental safety.

With the rapid growth of large-scale livestock farming in China, the safe disposal and resource utilization of anaerobic biogas residue (BR) have become critical challenges. This study systematically investigated the temperature-dependent (400-700 °C) transformation of piggery biogas residue pyrolysis products (biochar, tar/wood vinegar, pyrolysis gases) and their environmental risks. Results show that pyrolysis temperature significantly affects product distribution and properties: At 600 °C, biochar exhibits the maximum specific surface area (38.

Influence of oropharyngeal therapy with mother's own milk on the microbiome and metabolome of very preterm infants: a pilot study.

Background: Oropharyngeal therapy with mother's own milk (OPT-MOM) may serve as a promising therapeutic approach to elicit immunoprotective and anti-inflammatory benefits for preterm infants.

Objectives: This prospective pilot study aims to investigate whether OPT-MOM alters the oral microbiota, gut microbiota and metabolic profiles in very preterm infants.

Methods: The eligible infants were divided into two groups: the OPT-MOM group and the control group.

Optimization of degradation conditions and elucidation of novel biodegradation pathways for sulfamonomethoxine by a novel strain.

Unlabelled: As a commonly used sulfonamide antibiotic, the efficient reduction of sulfamonomethoxine (SMM) residue in the environment is a critical issue that urgently needs to be addressed. However, there is limited understanding of the microbial conditions needed for efficient SMM degradation and its mechanisms. Therefore, this study screened a new strain, sp.

MR-based evaluation of osseous cervical neural foraminal stenosis (OCNFS) using fast-field-echo resembling CT using restricted echo-spacing (FRACTURE).

Purpose: This study aimed to assess the feasibility of fast-field-echo resembling CT using restricted echo-spacing (FRACTURE) for evaluating osseous cervical neural foraminal stenosis (OCNFS).

Methods: A total of 280 cervical foramina from 28 patients with cervical radiculopathy (CR) were analyzed on oblique sagittal CT, FRACTURE, T1WI, and T2WI from bilateral C2/3 to C6/7 segments by three readers. CT served as the reference standard to identify OCNFS.

The role of peripapillary vessel density and retinal nerve fiber layer thickness in diagnosing and monitoring myopic glaucoma.

Objective: To investigate changes in peripapillary vessel density (pVD) and retinal nerve fiber layer thickness (pRNFL) in highly myopic glaucoma patients compared to non-highly myopic glaucoma patients and healthy controls, and to evaluate their diagnostic capabilities using optical coherence tomography angiography (OCTA), and to explore the relationship between these biomarkers and visual function.

Methods: A total of 382 eyes were recruited, including 101 highly myopic glaucoma eyes, 101 highly myopic control eyes, 90 non - highly myopic glaucoma eyes, and 90 non - highly myopic control eyes. Propensity score matching (PSM) was applied to balance age and axial length between groups.

Corrigendum: Totally laparoscopic total gastrectomy with Uncut Roux-en-Y for gastric cancer may improve prognosis: a propensity score matching comparative study.

[This corrects the article DOI: 10.3389/fonc.2022.

Epstein-Barr virus mRNA vaccine synergizes with NK cells to enhance nasopharyngeal carcinoma eradication in humanized mice.

The close association between nasopharyngeal carcinoma (NPC) and Epstein-Barr virus (EBV) infection highlights the potential of therapeutic vaccination against viral antigens as an attractive immunotherapy for treating EBV NPC. Maximizing vaccine efficacy often requires selecting optimal T cell epitopes and incorporating co-treatment strategies. Here, we analyzed genomic mutations of 283 cancer-associated EBV strains and predicted epitopes with broad human leukocyte antigen (HLA) coverage from high-frequency nonsynonymous mutations.

Integrating microbial community dynamics and emerging contaminants (ECs) for precisely quantifying the sources in groundwater affected by livestock farming.

Livestock farming is a major emission source of emerging contaminants (ECs); improper management of ECs could lead to severe groundwater pollution. However, research on accurately controlling the impact of large-scale livestock pollution in groundwater and quantifying sources of ECs pollution from livestock farming to formulating effective control measures is scarce. For the first time, the groundwater near four livestock farms (broiler, dairy, aquaculture, and pig farms) was selected as the research object to characterize the ECs, analyze the impact of ECs on microbial communities, and identify the pollution sources of livestock groundwater by the fast expectation-maximization of microbial source tracking (FEAST).

New insight into intestinal toxicity accelerated by aged microplastics with triclosan: Inflammation regulation by gut microbiota-bile acid axis.

The combined toxic effects of microplastics (MPs) and their carried contaminants on organisms have been widely concerned; however, the health risks and its mechanism of "gut microbiota-host metabolism (bile acids, BA)" remain unknown. Herein, Xenopus tropicalis were exposured to aged polystyrene MPs carried triclosan (aPS+TCS) and single (a)PS-MPs & TCS, respectively. The bioaccumulation of TCS in the gut of X.

Solothrips brevisetis gen. et sp. nov. with a single pair of ocellar setae (Thysanoptera, Thripidae).

Among Thripinae the number and position of setal pairs around the ocellar triangle is an important diagnostic characteristic. Solothrips brevisetis gen. et sp.

Fine Particulate Matter () and the Blood-Testis Barrier: An and Mechanistic Study.

Background: Fine particulate matter [particulate matter (PM) with aerodynamic diameter of ()] is considered a major component of ambient PM. Exposure to was shown to be associated with male reproductive system injury. Ferroptosis is regarded as an iron-dependent programmed cell death that is associated with the pathological process.

Transcriptomic analysis of the inhibition mechanisms against by antibacterial aptamer B4.

is a common bacterial pathogen in aquaculture, often leading to visceral white spot disease in large yellow croakers (). Previous studies have found that certain aptamers show an efficient antibacterial effect against this pathogen. In this study, we analyzed the transcriptome of to get insights into the antibacterial and inhibitions mechanisms following exposure to the aptamer B4.

Response surface methodology and Box-Behnken design optimization of Sulfaquinoxaline removal efficiency and degradation mechanisms by Bacillus sp. strain DLY-11.

Antibiotic pollution, particularly the persistence of Sulfaquinoxaline (SQ) residues in livestock and poultry farming environments, has emerged as a pressing environmental concern. Despite this, there remains a limited understanding of the optimized conditions and mechanisms for the efficient degradation of SQ by microorganisms. To address this knowledge gap, we isolated Bacillus sp.

Exploring the value of hybrid capture-based next-generation sequencing technology in the suspected diagnosis of bloodstream infections.

Background: Determining the source of infection is significant for the treatment of bloodstream infections (BSI). The gold standard of blood infection detection, blood cultures, have low positive rates to meet clinical needs. In this study, we investigated the ability of hybrid capture-based next generation sequencing technology to detect pathogens in peripheral blood samples collected from patients with suspected BSI.

[Digital Intelligence Drives the High-Quality Development of the Healthcare Service System: Development Mechanisms and Implementation Pathway].

The rapid development of digital intelligence technologies is providing a powerful boost to the high-quality development of the healthcare system. Considering the current state of our healthcare services and guided by General Secretary Xi Jinping's insights on new quality productive forces and the directives from Third Plenary Session of Communist Party of China's 20th Central Committee, the high-quality development of the healthcare service system should focus on digital intelligence technologies such as cloud computing, big data, privacy computing, blockchain, Internet of Things (IoT), mobile computing, and AI. The key measures should include the optimization of production factors, services, and governance.

Engineering cell membrane-camouflaged COF-based nanosatellite for enhanced tumor-targeted photothermal chemoimmunotherapy.

Dendritic cells (DCs) activation is crucial for regulating the antitumor immune response. However, the tumor's immunosuppressive environment significantly impedes antigen presentation and DCs maturation, thereby limiting the effectiveness of cancer immunotherapy. To address this challenge, we developed tumor cell membrane-coated covalent organic framework (COF) nanoparticles, loaded with mannose-modified gold nanoparticles and doxorubicin (Dox).

Air pollution's numerical, spatial, and temporal heterogeneous impacts on childhood hand, foot and mouth disease: a multi-model county-level study from China.

Background: While stationary links between childhood hand, foot and mouth disease (HFMD) and air pollution are known, a comprehensive study on their heterogeneous relationships (nonstationarity), jointly considering numerical, temporal and spatial dimensions, has not been reported.

Methods: Monthly HFMD incidence and air pollution data were collected at the county level from Sichuan-Chongqing, China (2009-2011), alongside meteorological and social environmental covariates. Key influential factors were identified using random forest (RF) under the stationary assumption.

Trimetallic-doped carbon nitride achieves chondroitin sulfate degradation via a free radical degradation strategy.

Traditional Fenton principles for degrading polysaccharides, including chondroitin sulfate (CS), are fraught with limitations, such as strict pH-dependence, higher temperature requirements, desulfurization, and environmentally perilous. In this study, an effective Fenton-like system comprising trimetallic-doped carbon nitride material (tri-CN) with hydrogen-bonded melamine-cyanuric acid (MCA) supramolecular aggregates as its basic skeleton was engineered to overcome the challenges of traditional methods. Detailed material characterizations revealed that, compared to monometallic-doped or bimetallic-doped counterparts, tri-CN offered a larger surface area, higher porosity, and increased metal loading, thereby enhancing reactant accessibility and polysaccharide degradation efficiency.

PM chemical components are associated with in-hospital case fatality among acute myocardial infarction patients in China.

Recent studies have linked the cardiovascular events with the exposure to ambient fine particulate matter (PM); however, the impact of PM chemical components on acute myocardial infarction (AMI) case fatality remains poorly understood. To address this gap, we included 178,340 hospitalised patients with AMI utilising the inpatient discharge database from Sichuan, Shanxi, Guangxi, and Guangdong, China spanning 2014-2019. We evaluated exposure to PM and its components (black carbon (BC), organic matter (OM), sulphate (SO), nitrate (NO), and ammonium (NH)) using bilinear interpolation based on the patient's residential address.

Adjustable focusing property of circular Airyprime beam through Fourier space modulation.

Airyprime beams are known for their powerful autofocusing property, which are further enhanced by the introduction of a circular structure-circular Airyprime beam (CAPB). We derive an asymptotic expression of the CAPB in Fourier space (FS) and verify its accuracy by the numerical Fourier transform (FT) method. Through FS modulation on it, adjustable control of autofocusing property of the FS-modulated CAPB can be achieved, whose lower and upper limits can reach 8.