Publications by authors named "Xiao-Yu Zhao"

The health of urban trees is jointly influenced by species-specific environmental adaptability and habitat heterogeneity, posing severe challenges for management. We investigated landscaping trees in Beijing, established a five-tier health evaluation system (healthy, sub-healthy, unhealthy, severe decline, and moribund) comprising 14 indicators. Then, we analyzed current health status and the influence of six typical habitats: dense forest, sparse forest, tree belt, tree pond, waterside, and buildingside.

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Background: Atherogenic index of plasma (AIP) is recognized as a marker for atherosclerosis, but the impact of long-term AIP exposure on carotid plaque remains unknown.

Objectives: The objective of the study is to assess the associations of cumulative AIP (cumAIP), incorporating the time course of cumAIP accumulation with the risk of carotid plaque.

Methods: A total of 9,202 participants from the Beijing Health Management Cohort were followed up until December 31, 2021.

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Objective: This study aims to assess the diagnostic efficacy of using a combination of ultrasonic probes including convex array probe, linear array probe, and intracavitary probe, for the detection of adenomyosis at the gallbladder fundus.

Methods: A total of 121 outpatients with suspected diagnosis of gallbladder adenomyosis were enrolled in this study. All patients underwent conventional ultrasound examination of gallbladder floor with convex array probe, linear array probe and intraluminal probe.

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This thesis aims to investigate the role of extracellular vesicles of Lactobacillus plantarum (LPEVs) in the regulation of high-fat diet (HFD)-induced disorders of lipid metabolism.We used ultracentrifugation to obtain LPEVs and performed preliminary characterization. After an obese mouse model was established via HFD feeding, LPEVs were used to treat mice with lipid metabolism disorders, and changes in the body weight, blood lipid levels, tissue levels, intestinal flora structure, differential metabolites, and regulation of key signaling pathway genes in these mice were observed.

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Background: Choledocholithiasis is a common benign disease of the biliary tract. We identified a particular type of choledocholithiasis characterized by sudden narrowing of the common bile duct at the site of impaction, which caused a marked increase in surgical difficulty and risk compared to treatment for typical choledocholithiasis. This phenomenon has not been described in previous studies.

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The quality of eggshells holds substantial economic significance and serves as a critical selection criterion in poultry breeding. Eggshell translucency significantly impairs their aesthetic quality, which is structurally attributed to the thinning of the eggshell membrane or reduced tensile strength. In this study, 836 dwarf white hens were selected, with 45 hens each assigned to the opaque group and the translucent group.

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Maternal exposure to fine particulate matter (PM) and residential greenness both influence fetal growth. No previous studies have examined their sex-specific and interaction effects. We aim to evaluate the sex-specific effects in these associations and exposure interactions.

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Introduction: Double-infrared (IR-D) and laser energy sources (LAS) are two types of newly beak treatment equipment. Although the IR-D and LAS techniques have been developed by changing the number and type of energy sources, their effects on layer chicks are yet to be systematically studied.

Methods: In this study, we placed 4,416 layer chicks into groups subjected to single-infrared energy sources (IR-S), IR-D, and LAS beak treatment on hatching day and a sham untreated control (CON) group; the beak sloughing, growth and histomorphology, body weight (BW), feed intake (FI), and other performance indicators were measured.

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Peroxisomes are vital but often overlooked metabolic organelles. We found that excessive interferon signaling remodeled macrophage peroxisomes. This loss of peroxisomes impaired inflammation resolution and lung repair during severe respiratory viral infections.

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Objective: Carbapenem-resistant Pseudomonas aeruginosa (CRPA) is a major contributor to healthcare-associated infections globally. The aim of this study was the impact of the COVID-19 pandemic on the genomic characteristics of P. aeruginosa, particularly clinical CRPA isolates.

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Somatic cell nuclear transfer (SCNT) has been successfully employed across various mammalian species, yet cloned animals consistently exhibit low pregnancy rates, primarily due to placental abnormalities such as hyperplasia and hypertrophy. This study investigated the involvement of the Hippo signaling pathway in aberrant placental development in SCNT-induced bovine pregnancies. SCNT-derived cattle exhibited placental hypertrophy, including enlarged abdominal circumference and altered placental cotyledon morphology.

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Background: Ependymoma with lipomatous differentiation is a rare type of ependymoma. The ZFTA fusion-positive supratentorial ependymoma is a novel tumor type in the 2021 World Health Organization classification of central nervous system tumors. ZFTA fusion-positive lipomatous ependymoma has not been reported to date.

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Trace organic contaminants (TrOCs) in reclaimed water can pose potential ecological and health risks during long-term reuse, but the current water quality standards have not restricted their limits. For preventing and controlling the potential risks from TrOCs, an integrated method EHL for identifying priority pollutants in reclaimed water was proposed. This method followed three steps: First, a meta-analysis was performed to assess the exposure of TrOCs in reclaimed water, and a database of TrOCs exposure (E) was established.

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Soil microbial communities play a crucial role in maintaining diverse ecosystem functions within the saline-alkali soil ecosystems. Therefore, in this study, we collected various saline-alkaline soils from across the Inner Mongolia Hetao irrigation area. The soil chemical properties were analyzed, and the microbial diversity of bacteria and fungi was measured using 16 S rRNA and ITS rRNA amplicon sequencing.

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Article Synopsis
  • - The study examines the relationship between metabolic dysfunction-associated fatty liver disease (MAFLD) and nonalcoholic fatty liver disease (NAFLD), and their links to the risk of developing peripheral artery disease (PAD) in two large cohort studies.
  • - Results indicate that individuals with MAFLD experience a higher risk of incident PAD compared to those without MAFLD, with the strongest association found in the MAFLD-only group. In contrast, the NAFLD-only group did not show an independent association with PAD risk.
  • - The study concludes that MAFLD and its diabetic subtype are significantly linked to increased PAD incidence, highlighting the need for targeted screening and preventive measures in individuals with these liver conditions to improve
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Article Synopsis
  • Colistin, often used as the last-resort antibiotic against gram-negative bacteria, faces efficacy challenges due to rising resistance, prompting the search for effective adjuvants like paeonol.
  • This study assessed the synergistic effects of paeonol on colistin’s antibacterial activity through various assays and in vivo models, revealing that paeonol significantly enhances colistin's effectiveness, particularly against Klebsiella pneumoniae.
  • The research identified specific structural components of paeonol that contribute to this adjuvant effect and suggested that the combination increases membrane disruption and oxidative damage in bacteria, while also reducing colistin resistance development.
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Rationale: Traumatic brain injury frequently leads to prolonged coma, posing significant medical management challenges. Complementary therapies, including traditional Chinese herbal medicine, have been investigated as potential interventions in comatose patients. Chinese aromatic herbs, such as Borneolum (Bingpian), Moschus (Shexiang), and Acori tatarinowii rhizoma (Shichangpu), have long been believed to be "resuscitation with aromatics" based on traditional Chinese medicines theory.

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Eggshell translucency is a widespread issue in the field of egg quality. Previous research has established that the heritability of eggshell translucency is relatively low or moderate. Scientists have also successfully identified SNP loci related to eggshell translucency on different chromosomes by using gene chips and single-variant GWAS.

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Purpose: To assess the influence of ocular biometric parameters on intraocular lens (IOL) tilt and decentration after cataract surgery.

Methods: Patients scheduled for cataract surgery were screened for inclusion in this prospective cohort study. Tilt and decentration of the crystalline lens and IOL were measured using the CASIA2 (Tomey).

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Few T cells infiltrate into primary brain tumors, fundamentally hampering the effectiveness of immunotherapy. We hypothesized that Toxoplasma gondii, a microorganism that naturally elicits a Th1 response in the brain, can promote T cell infiltration into brain tumors despite their immune suppressive microenvironment. Using a mouse genetic model for medulloblastoma, we found that T.

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Article Synopsis
  • The study investigates the effectiveness of ultrasound in diagnosing thyroid nodules that have a spoke-wheel blood flow pattern by comparing ultrasound data with pathological results.
  • Out of 64 patients studied, 47 had malignant nodules and 17 had benign, with specific ultrasound features such as central scars indicating malignancy and coarse calcification suggesting benignity.
  • The research highlights that combining the detection of central scars and coarse calcification enhances the diagnostic accuracy of standard thyroid imaging reporting systems (ACR TI-RADS and C-TIRADS) for these types of nodules.
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The decrease in eggshell quality seriously affects production efficiency. Guinea fowl (GF) eggs possess strong eggshells because of their unique crystal structure, and few systematic studies have compared laying hen and GF eggs. Sixty eggs were collected from both 40-week-old Dwarf Layer-White (DWL-White) laying hens and GF, and the eggshell quality, ultrastructure, bubble pores, and composition were measured.

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Toxoplasma gondii is an obligate intracellular parasite of rodents and humans. Interferon-inducible guanylate binding proteins (GBPs) are mediators of T. gondii clearance, however, this mechanism is incomplete.

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Objective: To investigate the impact of renin-angiotensin-aldosterone-system (RAAS) inhibitors on complement component 4 (C4) serum levels in patients with immunoglobulin A nephropathy (IgAN).

Methods: A total of 423 patients diagnosed with IgAN at Shanxi Provincial People's Hospital, China, between 1 January 2017 and 31 December 2021 were divided into two groups, a RAAS inhibitor group and a non-RAAS inhibitor group, for comparative analysis.

Results: The RAAS inhibitor group exhibited significantly increased C4 and eGFR levels and had a higher proportion of patients with hypertension compared with the non-RAAS inhibitor group.

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Article Synopsis
  • Floral patterns in rice are vital for its reproductive success, and the gene SL1 encodes a transcription factor important for flower development, though its mechanisms are not fully understood.
  • The study indicates that SL1 interacts with floral homeotic genes, specifically SPW1 and DL, influencing stamen development and maintaining floral meristem destiny.
  • Evidence shows that SL1 directly binds to and activates SPW1 and FON1, forming a regulatory network crucial for specifying floral organ identities and controlling floral meristem fate in rice.
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