Preterm birth rates and risk factors among women with cervical incompetence undergoing prophylactic cerclage: a systematic review and meta-analysis.

Background: Preterm birth is the leading cause of neonatal mortality and long-term health complications. Cervical cerclage (CC) represents a critical intervention for extending pregnancy duration and enhancing neonatal survival in patients diagnosed with cervical insufficiency. The aim of this study was to identify risk factors for preterm birth through a meta-analysis comparing outcomes between preterm and full-term deliveries following non-emergency CC.

Engineering the electronic structure of Fe-MoO@PEG to increase sonodynamic and multi-nanozyme activities for anticancer therapy.

Both sonodynamic therapy (SDT) and nanozymes can be considered specialized forms of catalysis, which are related to the electron structure. In this work, Fe doping was employed to introduce electronic localization and spin polarization toward porous MoO nanospheres to improve the anticancer catalytic efficiency. All the Fe atoms are single-distributed to substitute for some lattice positions of Mo.

AUF1 Is a Novel Negative Regulator for Hepatitis B Virus Replication Acting Through a Posttranscriptional Manner.

Elucidating the molecular mechanisms underlying hepatitis B virus (HBV)-host interactions will hold promise for identifying novel therapeutic targets for HBV. This study aims to investigate the functional interplay and regulatory mechanisms between HBV and the AU-rich element RNA-binding protein 1 (AUF1). We demonstrate that AUF1 inhibits HBV replication and expression in HBV-infected HepG2-NTCP cells, HepG2 cells cotransfected with prcccDNA and pCMV-Cre plasmids, and HepAD38 cells.

Piezoelectric nanofiber-based intelligent hearing system.

Hearing loss, affecting individuals of all ages, can impair education, social function, and quality of life. Current treatments, such as hearing aids and implants, aim to mitigate these effects but often fall short in addressing the critical issue of accurately pinpointing sound sources. We report an intelligent hearing system inspired by the human auditory system: asymmetric well-aligned piezoelectric nanofibers combined with neural networks to mimic natural auditory processes.

GhIAA14-GhARF7 module coordinates auxin-mediated cellulose biosynthesis during secondary cell wall thickening in cotton fibers.

The phytohormone auxin is critical for cotton fiber development, yet its regulatory mechanisms during secondary cell wall (SCW) thickening remain poorly understood. Our investigation revealed that the dynamic patterns of auxin accumulation exhibit stage correlations with fiber development, with lower levels during rapid elongation (5-10 days post-anthesis [DPA]) and significantly higher level during SCW thickening (15-25 DPA). Meanwhile, the auxin content in superior-fiber cotton Gossypium barbadense is higher than in G.

Cardiac shock wave therapy-induced exosome derived from OGD/R-treated H9c2 cells carrying miR-98-5p promote HUVECs angiogenesis.

Cardiac shock wave therapy (CSWT) as an effectual therapy can activate the function of exosomes to a certain extent. Here, we attempted to examine the role of CSWT in exosome released from ischemic cardiomyocytes and its function in myocardial ischemia recovery. The exosomes derived from OGD/R-treated H9c2 (H9c2-OGD/R-Exo) and CSWT-treated OGD/R-stimulated H9c2 (CSWT-H9c2-OGD/R-Exo) were performed with small RNA sequencing to determine miRNAs that differentially expressed.

Impact of the COVID-19 Pandemic on ACO Prevalence Among AECOPD Patients (2019-2023) and Clinical Characteristics by Blood Eosinophil Levels.

Purpose: This study aimed to evaluate changes in the prevalence of Asthma-COPD Overlap (ACO) among patients with Acute Exacerbations of COPD (AECOPD) from 2019 to 2023. It also compared the clinical characteristics of patients across EOS thresholds (50, 150, and 300 cells/μL) to identify disease severity markers and guide individualized treatment strategies.

Patients And Methods: Clinical data from AECOPD and ACO patients hospitalized at the Second Hospital of Hebei Medical University between January 2019 and December 2023 were analyzed.

The relationship between renal function indicators and preeclampsia in the second trimester of pregnancy: a retrospective study.

Background: To investigate the relationship between serum renal function indicators and preeclampsia (PE) in pregnant women at second trimester of pregnancy, determine the optimal critical values of the above indicators, and further identify the independent risk factors of PE.

Methods: We assessed the renal function indicators in second trimesters of 137 pregnant women with PE and 137 normal pregnant women who delivered at Shijiazhuang Fourth Hospital between January 2020 to December 2022. Paired -tests, paired Mann-Whitney U tests, and Chi-square tests were used to evaluate differences of clinical data between the two groups.

A retrospective study of the correlation between high serum ferritin levels and the risk of gestational diabetes mellitus in midpregnant women.

Aims: Gestational diabetes mellitus (GDM) is any degree of glucose intolerance with onset or first detection during pregnancy, with an inconsistent association with serum ferritin (SF). We aimed to ascertain the relationship between SF and the risk of GDM in mid-pregnancy and provide evidence for implementing clinical individualized and reasonable iron supplementation regimens.

Methods: A retrospective study was conducted to investigate 1,052 pregnant women at 24-28 weeks of gestation who were examined in the obstetrics department of The Fourth Hospital of Shijiazhuang from January 2019 to December 2021.

An Investigation of Extended-Dimension Embedded CKF-SLAM Based on the Akaike Information Criterion.

Simultaneous localization and mapping (SLAM) faces significant challenges due to high computational costs, low accuracy, and instability, which are particularly problematic because SLAM systems often operate in real-time environments where timely and precise state estimation is crucial. High computational costs can lead to delays, low accuracy can result in incorrect mapping and localization, and instability can make the entire system unreliable, especially in dynamic or complex environments. As the state-space dimension increases, the filtering error of the standard cubature Kalman filter (CKF) grows, leading to difficulties in multiplicative noise propagation and instability in state estimation results.

PlZAT10 binds to the ABA catabolism gene PlCYP707A2 promoter to mediate seed dormancy release in Paeonia lactiflora.

PlZAT10-PlCYP707A2 module promotes Paeonia lactiflora seeds germination. The herbaceous peony (Paeonia lactiflora) seeds exhibit double dormancy in the epicotyl and hypocotyl, which significantly inhibits the process of cultivation and breeding of new varieties. Nevertheless, the molecular mechanism underlying seed dormancy release in P.

Identification of Rapeseed ( L.) Plant Height-Associated QTL Using BSA-seq and RNA-seq.

Plant height (PH) is a critical agronomic trait in , significantly impacting yield. Consequently, identifying genes associated with plant height is a pivotal objective in oilseed rape breeding. This study employed a combination of bulk segregant analysis sequencing (BSA-seq) and RNA sequencing (RNA-seq) for analysis.

Liquid Crystalline Hydroxyapatite Nanorods Orchestrate Hierarchical Bone-Like Mineralization.

Bone matrix exhibits exceptional mechanical properties due to its unique nanocomposite structure of type I collagen fibrils and hydroxyapatite (HAp) nanoparticles in hierarchical liquid crystalline (LC) order. However, the regeneration mechanism of this LC structure is elusive. This study investigates the role of the LC structure of HAp nanorods in guiding aligned mineralization and its underlying molecular mechanism.

Evaluation of alanine aminotransferase/aspartate aminotransferase ratio and high-density lipoprotein for predicting neonatal adverse outcomes associated with intrahepatic cholestasis of pregnancy.

Background: To determine the association between lipid metabolism and intrahepatic cholestasis of pregnancy (ICP), and explore the value of maternal alanine aminotransferase/aspartate aminotransferase (ALT/AST) and high-density lipoprotein (HDL) in predicting adverse neonatal outcomes in women with ICP.

Methods: A total of 147 pregnant women with ICP admitted to The Fourth Hospital of Shijiazhuang and 120 normal pregnant women in the same period were selected in this study. The Mann-Whitney U test and Chi-square tests were used to compare the differences in clinical data.

Bioinformatic Analysis of the Significance of the KIR2DL4 Gene in Recurrent Implantation Failure.

Related studies have pointed out that Killer immunoglobulin-like receptor 2DL4 (KIR2DL4) was associated with vascular remodeling in early pregnancy, and it might play an important role in immunity. In this study, recurrent implantation failure (RIF)-related GSE58144 dataset was extracted from the Gene Expression Omnibus (GEO) database. Firstly, the immune micro-environment analyses were conducted to analyze the pathogenesis of KIR2DL4 in RIF.

Physiological and transcriptomic responses of silkworms to graphene oxide exposure.

The growing use of nanomaterials has sparked significant interest in assessing the insect toxicities of nanoparticles. The silkworm, as an economically important insect, serves as a promising model for studying how insects respond to harmful substances. Here, we conducted a comprehensive investigation on the impact of graphene oxide (GO) on silkworms using a combination of physiological and transcriptome analyses.

New-onset atrial fibrillation following arteriovenous fistula increases adverse clinical events in dialysis patients with end-stage renal disease.

Background: End-stage renal disease (ESRD) patients have a high potential cardiovascular burden, and cardiovascular disease (CVD) is the leading cause of death in maintenance haemodialysis (MHD) patients. Arteriovenous fistula (AVF) is the preferred vascular access for MHD patients, but AVF significantly affects the haemodynamics of the cardiovascular system, leading to or exacerbating CVD, including atrial fibrillation (AF). This study aimed to evaluate the impact of AVF on cardiac function, especially of the left atrium (LA), in patients with ESRD and to further explore the relationship between AVF establishment and the occurrence of AF.

Unraveling the role of PlARF2 in regulating deed formancy in Paeonia lactiflora.

PlARF2 can positively regulate the seed dormancy in Paeonia lactiflora Pall. and bind the RY cis-element. Auxin, a significant phytohormone influencing seed dormancy, has been demonstrated to be regulated by auxin response factors (ARFs), key transcriptional modulators in the auxin signaling pathway.

A Study on Dimensionality Reduction and Parameters for Hyperspectral Imagery Based on Manifold Learning.

With the rapid advancement of remote-sensing technology, the spectral information obtained from hyperspectral remote-sensing imagery has become increasingly rich, facilitating detailed spectral analysis of Earth's surface objects. However, the abundance of spectral information presents certain challenges for data processing, such as the "curse of dimensionality" leading to the "Hughes phenomenon", "strong correlation" due to high resolution, and "nonlinear characteristics" caused by varying surface reflectances. Consequently, dimensionality reduction of hyperspectral data emerges as a critical task.

Tunable Light-Responsive Polyurethane-urea Elastomer Driven by Photochemical and Photothermal Coupling Mechanism.

Light-driven soft actuators based on photoresponsive materials can be used to mimic biological motion, such as hand movements, without involving rigid or bulky electromechanical actuations. However, to our knowledge, no robust photoresponsive material with desireable mechanical and biological properties and relatively simple manufacture exists for robotics and biomedical applications. Herein, we report a new visible-light-responsive thermoplastic elastomer synthesized by introducing photoswitchable moieties (i.

Knowledge atlas of white matter microstructure: a bibliometric analysis.

Background: White matter microstructure is valued for being an indicator of neural network integrity, which plays an indispensable role in the execution of advanced brain functions. Although the number of publications has increased in the past 10 years, no comprehensive analysis has yet been conducted of this field. Therefore, this study aimed to identify the research hotspots and trends in research on white matter microstructure using a bibliometric analysis of the related literature published from 2013 to 2022.