Biocontrol Potential of Rhizosphere Bacteria Against Root Rot in Cowpea: Suppression of Mycelial Growth and Conidial Germination.

The cultivation of cowpea (), a vital vegetable crop, faces significant threats from spp.-induced root rot. In this study, three fungal pathogens ( HKFf, HKFi, and HKFo) were isolated from symptomatic cowpea plants, and we screened 90 rhizobacteria from healthy rhizospheres using six culture media.

Regulation of alkyl hydroperoxidase D by AhpdR in the antioxidant enzyme system of Pseudomonas aeruginosa.

An overabundance of reactive oxygen species (ROS) can disrupt the initial redox equilibrium within cells, resulting in metabolic issues, cellular harm, and potentially death. Pseudomonas aeruginosa is a widespread gram-negative environmental pathogen that causes serious infectious diseases in humans. P.

A machine learning-based model to predict intravenous immunoglobulin resistance in Kawasaki disease.

Accurate prediction of intravenous immunoglobulin (IVIG) resistance is crucial for the effective treatment of Kawasaki disease(KD). This study aimed to develop a predictive model for IVIG resistance in patients with Kawasaki disease and to identify the key predictors. The training set underwent cross-validation, and models were constructed using six machine learning algorithms.

Eosinophilic duodenitis misdiagnosed as acute pancreatitis in a child: a case report.

Background: Eosinophilic Gastrointestinal Disorders beyond Eosinophilic Esophagitis (non-EoE EGIDs) are chronic rare inflammatory disorders characterized by eosinophilic infiltration of the gastrointestinal (GI) tract.

Case Presentation: We report the first pediatric case of eosinophilic duodenitis (one type of the non-EoE EGIDs) with concomitant pancreatic reaction that was misdiagnosed as acute pancreatitis (AP). A 13-year-old girl was admitted to our hospital for a week of abdominal distension, vomiting, and epigastric pain that worsened recently.

Phase separation of Nur77 mediates XS561-induced apoptosis by promoting the formation of Nur77/Bcl-2 condensates.

The orphan nuclear receptor Nur77 is a critical regulator of the survival and death of tumor cells. The pro-death effect of Nur77 can be regulated by its interaction with Bcl-2, resulting in conversion of Bcl-2 from a survival to killer. As Bcl-2 is overexpressed in various cancers preventing them from apoptosis and promoting their resistance to chemotherapy, targeting the apoptotic pathway of Nur77/Bcl-2 may lead to new cancer therapeutics.

The role of IBV PL1pro in virus replication and suppression of host innate immune responses.

Background: Coronavirus papain-like proteases (PLpros) play a crucial role in virus replication and the evasion of the host immune response. Infectious bronchitis virus (IBV) encodes a proteolytically defective remnant of PL1pro and an active PL2pro. However, the function of PL1pro in IBV remains largely unknown.

A Lightweight Visual Simultaneous Localization and Mapping Method with a High Precision in Dynamic Scenes.

Currently, in most traditional VSLAM (visual SLAM) systems, static assumptions result in a low accuracy in dynamic environments, or result in a new and higher level of accuracy but at the cost of sacrificing the real-time property. In highly dynamic scenes, balancing a high accuracy and a low computational cost has become a pivotal requirement for VSLAM systems. This paper proposes a new VSLAM system, balancing the competitive demands between positioning accuracy and computational complexity and thereby further improving the overall system properties.

Removal of methylene blue by acrylic polymer adsorbents loaded with magnetic iron manganese oxides: Synthesis, characterization, and adsorption mechanisms.

Dyes pose significant risks for aquatic environments and biological health in general owing to their non-biodegradable nature, carcinogenicity, and toxicity. The effective treatment of dye wastewater has become an important research topic. In this study, acrylic polymers (AP) loaded with magnetic iron manganese oxides (MIMO) (AP/MIMO) were prepared and used for the first time for the adsorption of methylene blue (MB).

Feasibility study of on-line monitoring gadolinium based on neutron induced gamma activation.

Gadolinium is a soluble neutron poison for ensuring criticality safety of nuclear facility. A neutron induced gamma activation device was developed for the on-line measurement of gadolinium. The experimental device consisted of an Am-Be neutron source, six He detectors and a liquid scintillation detector.

SAR study of oxidative DIMs analogs targeting the Nur77-mediated apoptotic pathway of cancer cells.

Nur77, an orphan nuclear receptor, is implicated in regulating diverse cellular biological processes including apoptosis and inflammation. We previously identified BI1071 (DIM-C-pPhCFMeSO), an oxidized methanesulfonate salt of (4-CF-Ph-C-DIM), was a direct ligand of Nur77, which could activate the Nur77-Bcl-2 apoptotic pathway. To obtain more effective compounds targeting the Nur77-mediated apoptotic pathway, we designed and synthesized a series of BI1071 analogs by introducing various substituent groups in the indolyl-rings of BI1071.

Global trends in anesthetic research over the past decade: a bibliometric analysis.

Background: Anesthesia is the reversible inhibition of function of the central and/or peripheral nervous system using drugs or other means to ensure a successful operation. This inhibition is mainly manifested as a loss of sensation, especially pain.

Methods: Bibliometric analysis was used to identify the characteristics, hotspots, and frontiers of global anesthesiology scientific output during the past 10 years.

Extracellular vesicle-derived miR-1249-5p regulates influenza A virus-induced acute lung injury in RAW246.7 cells through targeting SLC4A1.

Acute lung injury (ALI) is characterized by tissue damage that leads to pulmonary epithelial membrane dysfunction and macrophage activation. Currently however, the exact mechanism by which the initial mediators of mouse lung epithelial (MLE-12) cells induce inflammation remines unclear. We constructed co-culture systems of MLE-12 cells with mouse macrophage cells RAW246.

Phase separation of Nur77 mediates celastrol-induced mitophagy by promoting the liquidity of p62/SQSTM1 condensates.

Liquid-liquid phase separation promotes the formation of membraneless condensates that mediate diverse cellular functions, including autophagy of misfolded proteins. However, how phase separation participates in autophagy of dysfunctional mitochondria (mitophagy) remains obscure. We previously discovered that nuclear receptor Nur77 (also called TR3, NGFI-B, or NR4A1) translocates from the nucleus to mitochondria to mediate celastrol-induced mitophagy through interaction with p62/SQSTM1.

The clinical characteristics and underlying causes of liver damage in patients with COVID-19 infection: Retrospective analysis.

Objectives: 2019-nCoV has become a global threat to human health. The primary objective of this study was to examine the hepatic damage in 2019-nCoV infected patients and the associated underlying causes.

Methods: In this retrospective study, a total of 68 laboratory-confirmed and 20 suspected COVID-19 cases from 23 January 2020 to 15 February 2020 were included.

The spatial organization of microbial communities during range expansion.

Microbes in nature often live in dense and diverse communities exhibiting a variety of spatial structures. Microbial range expansion is a universal ecological process that enables populations to form spatial patterns. It can be driven by both passive and active processes, for example, mechanical forces from cell growth and bacterial motility.

The complete chloroplast genome of an endangered species (Orchidaceae).

S. C. Chen & K.

The complete chloroplast genome of (Orchidaceae).

Schltr., is a critically Endangered orchid (IUCN). In this study, we report the first complete chloroplast (cp) genome of to provide the underlying information for genetic breeding and conservation studies of this species.

Adhesive Bacteria in the Terminal Ileum of Children Correlates With Increasing Th17 Cell Activation.

Humans and symbiotic bacteria are interdependent and co-evolved for millions of years. These bacteria communicate with human hosts in the gut in a contact-independent metabolite. Because most intestinal bacteria are non-adhesive, they do not penetrate the mucus layer and are not directly in contact with epithelial cells (ECs).

Adaptive slip ratio estimation for active braking control of high-speed trains.

Active braking control systems in high-speed trains are vital to ensure safety and are intended to reduce brake distances and prevent the wheels from locking. The slip ratio, which represents the relative difference between the wheel speed and vehicle velocity, is crucial to the design and successful implementation of active braking control systems. Slip ratio estimation and active braking control are challenging owing to the uncertainties of wheel-rail adhesion and system nonlinearities.

A Study on the Expression of SPRED1 and PBRM1 (Baf180) and their Clinical Significances in Patients with Gastric Cancer.

Background: To evaluate SPRED1 and PBRMl expression in patients with gastric cancer and determine the biological relationships of SPRED1 and PBRM1 with the occurrence and development of gastric cancer.

Methods: Tissue specimens of patients with gastric cancer at Jingzhou First People's Hospital were gathered from April 2016 to August 2018. SPRED1 and PBRMl (Baf180) protein expression levels were detected in the excised cancerous tissues and normal tissues (control group) of 80 patients with gastric cancer by immunohistochemical methods.

Foreign Object Intrusion Detection on Metro Track Using Commodity WiFi Devices with the Fast Phase Calibration Algorithm.

With continuous development in the scales of cities, the role of the metro in urban transportation is becoming more and more important. When running at a high speed, the safety of the train in the tunnel is significantly affected by any foreign objects. To address this problem, we propose a foreign object intrusion detection method based on WiFi technology, which uses radio frequency (RF) signals to sense environmental changes and is suitable for lightless tunnel environments.

A Rescue-Assistance Navigation Method by Using the Underground Location of WSN after Disasters.

A challenging rescue task for the underground disaster is to guide survivors in getting away from the dangerous area quickly. To address the issue, an escape guidance path developing method is proposed based on anisotropic underground wireless sensor networks under the condition of sparse anchor nodes. Firstly, a hybrid channel model was constructed to reflect the relationship between distance and receiving signal strength, which incorporates the underground complex communication characteristics, including the analytical ray wave guide model, the Shadowing effect, the tunnel size, and the penetration effect of obstacles.

An evolutionarily stable strategy to colonize spatially extended habitats.

The ability of a species to colonize newly available habitats is crucial to its overall fitness. In general, motility and fast expansion are expected to be beneficial for colonization and hence for the fitness of an organism. Here we apply an evolution protocol to investigate phenotypical requirements for colonizing habitats of different sizes during range expansion by chemotaxing bacteria.

[Age distribution characteristics of intestinal segmented filamentous bacteria and their relationship with intestinal mucosal immunity in children].

Objective: To investigate the age distribution characteristics of intestinal segmented filamentous bacteria (SFB) in children and their relationship with intestinal mucosal immunity.

Methods: The fresh feces of 177 children and the ileocecal fluid of 47 children during colonoscopy were collected. The SFB was determined by real-time PCR.